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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.ebi.ac.uk/Tools/sss/wublast/
Tool to find regions of sequence similarity within selected protein databases quickly, with minimum loss of sensitivity.
Proper citation: WU-BLAST (RRID:SCR_011824) Copy
http://www.ebi.ac.uk/ena/search/
A nucleotide sequence similiary search tool which is far faster than BLAST for large datasets, with only a marginal loss in search sensitivity.
Proper citation: ENA Sequence Search (RRID:SCR_013170) Copy
https://github.com/wilsonGW/SomaDetection
Source code for a machine learning method to detect somas on confocal microscopic images of the Drosophila brain. The method can be applied to the original raw images where the noises are not removed and the number of somas is unknown.
Proper citation: SomaDetection (RRID:SCR_015717) Copy
http://www.benoslab.pitt.edu/comir/
Data analysis service that predicts whether a given mRNA is targeted by a set of miRNAs. ComiR uses miRNA expression to improve and combine multiple miRNA targets for each of the four prediction algorithms: miRanda, PITA, TargetScan and mirSVR. The composite scores of the four algorithms are then combined using a support vector machine trained on Drosophila Ago1 IP data.
Proper citation: ComiR (RRID:SCR_013023) Copy
A web-server for fast comparative functional profiling of metagenomes.
Proper citation: CoMet (RRID:SCR_011925) Copy
http://tools.genxpro.net/omiras/
A web server for the annotation, comparison and visualization of interaction networks of non-coding RNAs derived from small RNA-Sequencing experiments of two different conditions.
Proper citation: omiRas (RRID:SCR_010833) Copy
http://phylopythias.bifo.helmholtz-hzi.de/index.php?phase=wait
Web Server for Taxonomic Assignment of Metagenome Sequences that is a fast and accurate sequence composition-based classifier that utilizes the hierarchical relationships between clades. Taxonomic assignments with the web server can be made with a generic model, or with sample-specific models that users can specify and create. Several interactive visualization modes and multiple download formats allow quick and convenient analysis and downstream processing of taxonomic assignments.
Proper citation: PhyloPythiaS (RRID:SCR_011923) Copy
http://compbio.med.harvard.edu/CGHweb/
Data analysis service enabling users to analyse their array-CGH data with multiple algorithms simultaneously.
Proper citation: CGHweb (RRID:SCR_010923) Copy
http://agvgd.iarc.fr/index.php
A freely available, web-based program that combines the biophysical characteristics of amino acids and protein multiple sequence alignments to predict where missense substitutions in genes of interest fall in a spectrum from enriched delterious to enriched neutral.
Proper citation: Align-GVGD (RRID:SCR_010772) Copy
https://figshare.com/articles/phi_toolbox_zip/3203326
Toolkit of MATLAB functions for computing integrated information ('phi' or 'Φ') from neural data. The toolbox consists of downloadable codes that perform practical computation.
Proper citation: Phi Toolbox (RRID:SCR_015549) Copy
http://www.mutationtaster.org/
Evaluates disease-causing potential of sequence alterations.
Proper citation: MutationTaster (RRID:SCR_010777) Copy
http://bioconductor.org/packages/EGSEA/
Method developed for RNA-sequencing data. EGSEA combines results from twelve algorithms and calculates collective gene set scores to improve the biological relevance of the highest ranked gene sets.
Proper citation: EGSEA (RRID:SCR_015036) Copy
http://www.cdtdb.brain.riken.jp/CDT/Top.jsp
Transcriptomic information (spatiotemporal gene expression profile data) on the postnatal cerebellar development of mice (C57B/6J & ICR). It is a tool for mining cerebellar genes and gene expression, and provides a portal to relevant bioinformatics links. The mouse cerebellar circuit develops through a series of cellular and morphological events, including neuronal proliferation and migration, axonogenesis, dendritogenesis, and synaptogenesis, all within three weeks after birth, and each event is controlled by a specific gene group whose expression profile must be encoded in the genome. To elucidate the genetic basis of cerebellar circuit development, CDT-DB analyzes spatiotemporal gene expression by using in situ hybridization (ISH) for cellular resolution and by using fluorescence differential display and microarrays (GeneChip) for developmental time series resolution. The CDT-DB not only provides a cross-search function for large amounts of experimental data (ISH brain images, GeneChip graph, RT-PCR gel images), but also includes a portal function by which all registered genes have been provided with hyperlinks to websites of many relevant bioinformatics regarding gene ontology, genome, proteins, pathways, cell functions, and publications. Thus, the CDT-DB is a useful tool for mining potentially important genes based on characteristic expression profiles in particular cell types or during a particular time window in developing mouse brains.
Proper citation: Cerebellar Development Transcriptome Database (RRID:SCR_013096) Copy
http://hyperbrowser.uio.no/hb/
A generic web-based system, providing statistical methodology and computing power to handle a variety of biological inquires on genomic datasets.
Proper citation: Genomic HyperBrowser (RRID:SCR_010909) Copy
http://weizhong-lab.ucsd.edu/metagenomic-analysis/
A customizable web server for fast metagenomic analysis.
Proper citation: WebMGA (RRID:SCR_011951) Copy
An ELN (electronic lab notebook) software application where researchers can record and organize their data by recording, dragging, and dropping elements. Users can utilize tools and features such as image annotation, search and filter, protocol templates, and team communication. The format of the ELN is customizable and can be rearranged at any point.
Proper citation: labfolder (RRID:SCR_013974) Copy
Database and repository of tissues relating to mouse models of breast cancer. Users can search and share models, and members can enter details of available material to share on a collaborative basis.
Proper citation: SEARCHBreast (RRID:SCR_014826) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 31,2023.
Proper citation: Australian Prostate Cancer Tissue Bank (RRID:SCR_013221) Copy
Provides access to large scale cell culture at reasonable cost. The Cell Culture Center has experience with the production of over 1700 cell lines. Numerous common cell lines, such as HeLa, CHO, 293, BHK, and hybridomas are routinely produced at the Center. We will adapt your cell line or custom protocol to large scale production then deliver the cells in the quantity and frequency you need. Large Scale Production Services: Mammalian cells: Suspension culture (1 to 400 liters per day), Anchorage dependent culture (1 to 200 roller bottles per batch), Purified monoclonal antibodies (10 mg to 100 grams), Non-hybridoma cell secreted proteins, Conditioned media Secreted proteins from suspension cultures can be produced in automated hollow fiber bioreactor systems. These systems may be considered after initial static culture production yields are determined. Upon determining the quantities requested by the investigator, the appropriate automated system will be used. For more information on the automated instrumentation available for the use of secreted protein production, please refer to the Biovest International web page (www.biovest.com). Working with our experienced personnel and quality controlled, state-of-the-art facilities also permits access to large quantities of cells or protein so you aren''t limited by the cell culture capacities of your own laboratory. The Center fulfills the needs of small research laboratories as well as those of larger institutions. Customers from all sectors of the research and industrial community are welcome to inquire about our services. If you''d like to inquire about using our services, use the contact infromation below. Key words: Cell, cells, culture, monoclonal, antibodies, antibody.
Proper citation: National Cell Culture Center (RRID:SCR_013467) Copy
A web-based application designed with an easy-to-use interface to facilitate the high-throughput assessment and prioritization of genes and missense alterations important for cancer tumorigenesis.
Proper citation: CRAVAT (RRID:SCR_012776) Copy
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