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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
MindSpec is a nonprofit organization that utilizes innovative bioinformatics strategies to accelerate research on common neurodevelopmental disorders. With our research we hope to foster discovery and development of treatments that alleviate the symptoms of affected individuals. Our core mission at MindSpec is to advance research on neurodevelopmental conditions. Founded in 2006, MindSpec is an independent, non-profit research organization established to facilitate the discovery of a cure for autism. Although the initial focus was autism, we have gradually expanded our scope to other neurological disorders. We develop bioinformatics strategies using current information technology platforms to build disease specific databases. At MindSpec we place a strong emphasis on translational research, that is, closing the gap between basic science discoveries and practical treatments with the potential of benefiting people who have autism. Goals: * Build an integrated, up-to-date, relevant, searchable resource on autism, AutDB. * Build a community of scientists, practitioners, educators, policymakers and people affected by autism to share and disseminate knowledge of autism. * Identify gaps in autism research around the world. * Identify priority areas in autism research based on real-world needs. * Build an autism dictionary and digital information library. * Address cultural differences in treatments for autism, a social disease. * Build knowledge about autism for immediate use.
Proper citation: MindSpec: Informatics for Neurodevelopmental Conditions (RRID:SCR_004439) Copy
CRBS is a UCSD organized research unit (ORU) that exists to provide human resources, high technology equipment, and administrative services to researchers engaged in fundamental research on cell structure and function relationships in central nervous system processes, cardiovascular networking, and muscular contraction through multiple scales and modalities. CRBS scientists investigate these processes through invention, refinement, and deployment of sophisticated technologies, especially: - High-powered electron microscopes that reveal three-dimensional cell structures - State-of-the-art X-ray crystallography and magnetic resonance analysis that provide detail on protein structures at high-resolution - Laser-scanning and confocal light microscopes that reveal molecules tagged with fluorescent markers as they traffic within cells and pass transfer signals within and between cells - High performance computing and grid-based integration of distributed data CRBS facilitates an interdisciplinary infrastructure in which people from biology, medicine, chemistry, and physics can work with those from computer science and information technologies in collaborative research. Researchers share interests in the study of complex biological systems at many scales, from the structures of enzymes, proteins, and the body's chemical communications network at atomic and molecular levels, to an organism's physiology, strength, and support at cellular and tissue levels. The CRBS infrastructure integrates resources for high-performance computing, visualization, and database technologies, and the grid-integration of large amounts of archival storage data. The California Institute for Telecommunications and Information Technology (Cal-IT2) and the San Diego Supercomputer Center (SDSC) are collaborators in simulating the activity of biological systems, analyzing the results, and organizing the growing storehouse of biological information. CRBS is an entity evolving as research evolves. It forges interactions with biotechnology and biocomputing companies for technology transfer. Interaction, collaboration, and multiscale research produce new perspectives, reveal fruitful research topics, lead to the development of new technologies and drugs, and train a new generation of researchers in biological systems. Sponsors: CRBS is supported by the University of California at San Diego.
Proper citation: Center for Research in Biological Systems (RRID:SCR_002666) Copy
The Digital Enterprise Research Institute is an internationally recognized institute in semantic web research, education and technology transfer. DERI brings together academic and industrial partners to boost innovation in science and technology, which directly contributes to the Irish government''s plan of transforming Ireland into a competitive knowledge economy.
Proper citation: Digital Enterprise Research Institute (RRID:SCR_004802) Copy
http://www.ncbi.nlm.nih.gov/pubmedhealth/
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on September 9, 2022. A consumer health database that provides up-to-date information on diseases, conditions, injuries, drugs, supplements, treatment options, and healthy living, with a special focus on comparative effectiveness research from institutions around the world. PubMed Health includes * consumer guides summarizing comparative effectiveness research * fact sheets on diseases and conditions * information on drugs and supplements * encyclopedic overviews of health topics * links to external Web sites PubMed Health has a special focus on comparative effectiveness research, in particular that research which evaluates the available evidence of the benefits and harms of different treatment options for different groups of people. In Comparative Effectiveness Research, experts often synthesize the evidence from dozens, or even hundreds, of individual studies.
Proper citation: PubMed Health (RRID:SCR_000512) Copy
http://researchprojects.kth.se/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. The KTH Research Project Database is intended to contain all the currently on-going projects at KTH. Sponsors: This resource is supported by the Royal Institute of Technology, Sweden,
Proper citation: Royal Institute of Technology: Research Project Database (RRID:SCR_000751) Copy
A database of neuroscience-related concepts that utilizes visualization tools for the purpose of research, education and knowledge discovery. The data comes from PubMed abstracts and an algorithm that assumes related terms will appear together. The topics can include computational modeling, behavioral functions and neurological degeneration.
Proper citation: brainSCANr (RRID:SCR_000500) Copy
https://www.jax.org/news-and-insights/2004/june/app-mouse-models-for-alzheimers-disease-research
An information resource about several models for mice to develop Alzheimer's-related characteristics as they age.
Proper citation: Mouse Models For Alzheimer's Disease Research (RRID:SCR_000708) Copy
http://www.calacademy.org/academy/blogs/
Academy scientists, journalists, adventurers and other staff members are blogging their stories and inviting questions and comments. Read current science news, hear from researchers in the field (Philippines, Sao Tome, Papua New Guinea), ask a question of an Academy naturalist, and much more.
Proper citation: California Academy of Sciences Blogs (RRID:SCR_000694) Copy
The DSMZ - Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (German Collection of Microorganisms and Cell Cultures) is the most comprehensive biological resource center in Europe. With more than 18.000 microorganisms, 1.200 plant viruses, 600 human and animal cell lines, 770 plant cell cultures and more than 7.100 cultures deposited for the purposes of patenting, DSMZ has demonstrated their obligation to serve science for decades. Main functions of DSMZ are: - to collect, maintain and store microorganisms and cell lines, as well as other biological material of relevance for applied biology, biotechnology, microbiology, teaching and other areas of research and general application; - to keep the scientific and industrial community informed on the contents of the collections by the means of catalogs, special lists, databases or electronic media; - to supply scientists and institutions with DSMZ cultures, in accordance with national and international laws such as the Infektionsschutzgesetz (Act dealing with protection against infection), the Genetic Engineering Act, the Foreign Trade Laws, the Convention on Biological Diversity as well as the DSMZ terms of supply; - to function as an internationally recognized collection center for the deposit of microorganisms, cell lines, and other biological material which have been cited in scientific literature or which are used in national or international test procedures (e.g. type strains, reference strains for national and international quality control regulations or susceptibility tests, strains with special properties, such as the production of enzymes, degradation of pollutants, host strains for plasmids, etc.); - to act as an International Depositary Authority (IDA) for the deposit of biological material for patent purposes according to the Budapest Treaty; - to act, in a confidential manner, as a center for the safe deposit of biological material; - to act as an advisory center for the scientific community and to offer teaching and service facilities. The DSMZ collections contain over 26 000 cultures (including 6500 patent deposits) representing more than 16 000 cultures of microorganisms (Archaea, Bacteria, plasmids, phages, yeasts, fungi), 750 plant cell cultures, 600 plant viruses, 700 antisera and 580 human and animal cell lines. Unique subcollections are held in the prokaryotes groups of acidophiles, alkaliphiles, halophiles, methanogens, phototrophs, thermophiles, and sulfate reducers. The research is focused on collection related fields which include: - Taxonomy - Evolution - Phylogeny - Microbial diversity and molecular assessment of diversity - Molecular systematics - Research on pathobiological aspects of leukemia-lymphoma cell lines applying classical and molecular genetics, immunological and cell biological methods * Development of cultivation and preservation methods for biological material * Characterization and identification of biological material
Proper citation: German Collection of Microorganisms and Cell Cultures (RRID:SCR_001711) Copy
https://catalog.data.gov/dataset?groups=research9385#topic=research_navigation
A catalog of high-value public science and research data sets from across the Federal Government.
Proper citation: Data.gov Science and Research Data Catalog (RRID:SCR_003927) Copy
FRAXA's mission is to accelerate progress toward effective treatments and ultimately a cure for Fragile X, by directly funding the most promising research. FRAXA also supports families affected by Fragile X and raises awareness of this important but relatively unknown disease. FRAXA was founded in 1994 by three parents of children with Fragile X, Katie Clapp, Michael Tranfaglia MD, and Kathy May, to support scientific research aimed at finding a treatment and a cure for Fragile X. Fragile X research is drastically underfunded, considering its high prevalence, prospects for a cure, and the promise that this research holds for advancing understanding of other disorders like autism, Alzheimer's disease, and X-linked mental retardation. FRAXA funds grants and fellowships at universities all over the world. We have funded more than $17 million dollars in top-notch science. FRAXA's management expenses have always been just 4% or less of income, as we have just one full-time staff, three part time staff, and hundreds of volunteer parents. Since FRAXA was founded, the Fragile X field has grown tremendously, due in large part to our grass-roots efforts. You can help us accomplish much more. FRAXA is a 501c3 tax-exempt organization; Tax ID 04-3222167
Proper citation: FRAXA Research Foundation (RRID:SCR_003125) Copy
http://bioinformatics.aecom.yu.edu/index.htm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 6, 2023. Primary informatics resource for joint research efforts of the Albert Einstein College of Medicine and Montefiore Medical Center to facilitate the study and understanding of biological processes, clinical disorders, pathologic abnormalities, and the relationships among them, using a wide variety of informatics techniques, applications, and user training. Their services include: * Collaboration on research design to enable effective data management throughout all phases of a project * Provision of management capability for large volumes of data generated by microarrays and related technologies * Provision and supports a software toolchest for data capture, retrieval, and analysis * Design and implementation of custom interfaces to incorporate existing or separately designed databases into the central data management architecture * Support for data management for the Biorepository, to enhance specimen storage, identification, and linkage with clinical data * Ensuring conformity of data elements and structures to national standards via participation in standards organizations, facilitating intramural and extramural collaboration * Providing individualized support to end-users with bioinformatics training needs * Serving as a bioinformatics liaison to other research institutes and organizations * Providing data management support for clinical research * Providing a common, secure repository for clinical, experimental, and biosample storage data
Proper citation: Einstein-Montefiore ICTR Research Informatics Core (RRID:SCR_003451) Copy
http://www.thesciencejobs.com/
An international career website for vacancies in academic, research and related professions in Science, Technology and Engineering. Announcements on upcoming conferences, workshops, training courses, etc are also available in the site. Job seekers can subscribe for email alerts on latest jobs/event postings. Employers can post jobs free of cost. The site can be viewed in about 35 world languages. About 500 jobs, fellowships and conference announcements are made available to the site every month. Users belong to more than 120 countries.
Proper citation: TheScienceJobs.com (RRID:SCR_005160) Copy
Brain tissue donation program at the UT Southwestern Memory Clinic that aims to utilize these contributions for research on Alzheimer's. Diagnosis of Alzheimer's disease or other dementias are made through autopsy, the results of which are available to family members.
Proper citation: UT Southwestern ADC Brain Tissue Donation Program (RRID:SCR_008837) Copy
http://accelrys.com/products/collaborative-science/biovia-pipeline-pilot/
Software used to automate the process of accessing, analyzing and reporting scientific data. This software can be used by a person with little or no software development experience can create scientific protocols that can be executed through a variety of interfaces including: BIOVIA Web Port, other BIOVIA solutions such as BIOVIA Electronic Lab Notebook, Isentris, Chemical Registration and third-party applications such as Microsoft SharePoint. The protocols aggregate and provide immediate access to volumes of research data, they automate the scientific analysis of data and allow researchers to explore, visualize and report results.
Proper citation: Pipeline Pilot (RRID:SCR_014917) Copy
A federally funded research and development center dedicated to biomedical research. NCI-Frederick partners with university, government, and corporate scientists to speed the translation of laboratory research into new diagnostic tests and treatments for cancer and HIV/AIDS. NCI-Frederick is comprised of more than 2,800 government- and contractor-employed biomedical researchers, laboratory technicians, and support staff and several cancer research centers. The FNLCR provides quick response capabilities and meets special long-term research and development needs for NCI that cannot be met as effectively by existing in-house or contractor resources.
Proper citation: NCI-Frederick (RRID:SCR_004880) Copy
Bio-Mixer is a web-based environment that supports the flexible exploration of biomedical ontologies. The concepts in the ontologies and their mappings can be explored in different views such as graph views, lists and timeline views. Drag-and-drop interaction can be used to show items and collections in different views, to create filtered views and to synchronize selections. Bio-Mixer enhances drag and drop with a new drop target highlighting and preview approach to make working with multiple collections and views easy. Bio-Mixer also provides support for ontology annotation and workspace sharing between collaborators. For more information, visit code.google.com/p/bio-mixer/
Proper citation: Bio-Mixer (RRID:SCR_004809) Copy
http://wiringthebrain.blogspot.com/
This blog highlights and comments on current research and hypotheses relating to how the brain wires itself up during development, how the end result can vary in different people and what happens when it goes wrong. It includes discussions of the genetic and neurodevelopmental bases of traits such as intelligence and personality characteristics, as well as of conditions such as schizophrenia, autism, dyslexia, epilepsy, synaesthesia and others.
Proper citation: Wiring the Brain (RRID:SCR_005528) Copy
BrainImmune is a free web-based reference that provides comprehensive and up-to-date information on the broad spectrum of medical research related to brain-immune interactions and their impact on health and disease. BrainImmune is written collaboratively by experts in the field from all around the world. Here, concise summaries of basic and clinical research describe how the brain and the immune system ''talk'' to each other in order to maintain homeostasis. BrainImmune is continually updated, with articles and opinions on history, the present state of the art, and new ideas and conceptual frameworks for the neurohormonal- and stress-immune interactions and their implications for common human diseases. Our goal in developing BrainImmune is to facilitate and advance neuroendocrine-immunology research, and the communication and collaborations in this vast interdisciplinary area.
Proper citation: BrainImmune (RRID:SCR_005418) Copy
http://science.kqed.org/quest/blog/
A blog that explores local science, nature, and environment issues & experiences in Northern California. A collaborative effort, our many writers come from local museums, zoos, science centers and research institutions, as well as KQED''s TV and Radio producers covering stories in the field.
Proper citation: QUEST Community Science Blog (RRID:SCR_005202) Copy
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