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http://sunnybrook.ca/research/?page=sri_core_tbank_home
Sunnybrook Research Institute''s tumour bank provides a mechanism for the optimal collection, storage and distribution of human tissue for investigative purposes. We collect both freshly frozen and formalin-fixed paraffin-embedded tumour and normal samples, retrospectively and prospectively (informed consent and confidential consent is obtained from patients before sample collection). We offer the 1. Distribution of tissue and data to interested investigators after approval from the institutional research ethics board and 2. Collaboration with various research investigators. Our mandate is to design, implement and manage the structures and processes to ensure the timely provision of tissue samples and associated data. We are currently building bank on four disease sites: breast, prostate, colorectal, gynecological. We are also creating and maintaining a database with a tissue tracking and inventory system, using TissueMetrix software.
Proper citation: Sunnybrook Tumour Bank (RRID:SCR_004138) Copy
http://www.lerner.ccf.org/gmi/gmb/
A biorepository is a place where investigators can deposit and store biological material, in this case samples derived from patients. Moreover, the Genomic Medicine Institute (GMI) takes this basic concept and elevates it to make the Genomic Medicine Biorepository (GMB) a full-service processing and banking laboratory that serves as the foundation for evidence-based research for the GMI, the Cleveland Clinic, and our collaborators. The process relies on a team of multi-disciplinary professionals coordinating their efforts in order to streamline medical research. This begins with dedicated physicians and genetic counselors identifying individuals with specific medical conditions indicating the possibility of genetic involvement. Once identified, biological material (e.g. blood, tissue, or saliva) is collected under the care of the patient''s doctor or by our clinicians and sent to the GMB. Once in the lab, the patient and their samples are assigned a unique identifier (to protect the patient''s personal information) and logged into a central database. This unique identifier accompanies all samples processed and banked for that individual. The specimens are then processed into research-relevant samples using proven laboratory techniques and state-of-the-art quality control practices. These samples include the isolation of DNA and RNA from white blood cells for genetic studies; collection of plasma for proteomic studies; and initiated immortalized cell lines from lymphocytes for in-vitro studies and biochemical research. These cell lines are able to be indefinitely stored in cryogenic suspension and are invaluable as a renewable resource for genetic and biochemical research. The GMB also processes genetic material from various tissues (both fresh and archived). Charis Eng, MD, PhD, Chair and Director of the GMI, has been the faculty oversight person of a human biorepository for the last eight years. Since then, our biorepository has received, cataloged, processed, and banked, in excess of 25,000 specimens. These samples are of numerous tissue types from patients and their family members located all over the world. Our biorepository has managed samples that have resulted in more than 150 original peer reviewed articles and greater than $25 million total direct costs in extramural funding over the last four years alone.
Proper citation: Cleveland Clinic Genomic Medicine Biorepository (RRID:SCR_004136) Copy
https://www.bips-institut.de/en/research/biobank.html
Biobank that contains more than 50,000 blood, urine and saliva samples as well as tissue materials from epidemiological field studies. The samples and DNA collected in various studies are increasingly being used for the investigation of genetic, environmental and life-style associated factors in the etiology and prognosis of cancer and other chronic diseases such as obesity, diabetes and metabolic syndrome.
Proper citation: Leibniz Institute for Prevention Research and Epidemiology Biobank (RRID:SCR_004094) Copy
http://www.lionseyeinstitute.org/about-us/
A nonprofit ocular research center with the largest eye bank in the world that provides eye tissue for research and transplantation to ophthalmic specialists and surgeons nationwide. They empower researchers to conduct real-time studies of healthy and diseased ocular tissue leading to a greater understanding of the events that lead to blindness. Their mission is to improve visual outcomes and quality of life for those who are blind or visually impaired through innovative ocular endeavors.
Proper citation: Lions Eye Institute for Transplant and Research (RRID:SCR_004008) Copy
Lifesharing Tissue Services provides the opportunity to improve and extend lives through the procurement, processing, storage and distribution of human tissue for transplantation and research. Originally established in 1984 to support the Burn Center at UCSD Medical Center, Lifesharing Tissue Services is a non-profit organization serving San Diego and Imperial counties in Southern California. The majority of tissues recovered by Lifesharing Tissue Services stay in this region to enable physicians to provide the best possible care for critically ill patients. Tissue grafting not only reduces pain and speeds recovery, but it also improves a patient''s quality of life. Fully accredited by the American Association of Tissue Banks (AATB) and the Food and Drug Administration (FDA), Lifesharing Tissue Services works to ensure the highest quality of tissue and technical service. Lifesharing is a member of the United Network for Organ Sharing (UNOS).
Proper citation: Lifesharing Tissue Services (RRID:SCR_004325) Copy
Database containing information on marketed medicines and their recorded adverse drug reactions. The information is extracted from public documents and package inserts. The available information include side effect frequency, drug and side effect classifications as well as links to further information, for example drug-target relations. The SIDER Side Effect Resource represents an effort to aggregate dispersed public information on side effects. To our knowledge, no such resource exist in machine-readable form despite the importance of research on drugs and their effects. The creation of this resource was motivated by the many requests for data that we received related to our paper (Campillos, Kuhn et al., Science, 2008, 321(5886):263-6.) on the utilization of side effects for drug target prediction. Inclusion of side effects as readouts for drug treatment should have many applications and we hope to be able to enhance the respective research with this resource. You may browse the drugs by name, browse the side effects by name, download the current version of SIDER, or use the search interface.
Proper citation: SIDER (RRID:SCR_004321) Copy
The Louisiana Organ Procurement Agency (LOPA) is the federally-designated organ procurement organization for the State of Louisiana. The agency focuses on educating the medical community and the general public about organ and tissue donation issues, working with families through the donation process, recovering donated organs and tissue, and placing the organs and tissue for transplant. Our mission is to save and enhance lives through organ and tissue donation. We envision a world in which no one suffers due to a lack of donor organs or tissues. LOPA has its main office in Metairie, with regional offices in Lafayette, and Shreveport. Additionally, LOPA has representatives in Baton Rouge, Alexandria, Lake Charles, and Monroe.
Proper citation: Louisiana Organ Procurement Agency - LOPA (RRID:SCR_004442) Copy
http://www.hgsc.bcm.tmc.edu/content/hapmap-3-and-encode-3
Draft release 3 for genome-wide SNP genotyping and targeted sequencing in DNA samples from a variety of human populations (sometimes referred to as the HapMap 3 samples). This release contains the following data: * SNP genotype data generated from 1184 samples, collected using two platforms: the Illumina Human1M (by the Wellcome Trust Sanger Institute) and the Affymetrix SNP 6.0 (by the Broad Institute). Data from the two platforms have been merged for this release. * PCR-based resequencing data (by Baylor College of Medicine Human Genome Sequencing Center) across ten 100-kb regions (collectively referred to as ENCODE 3) in 712 samples. Since this is a draft release, please check this site regularly for updates and new releases. The HapMap 3 sample collection comprises 1,301 samples (including the original 270 samples used in Phase I and II of the International HapMap Project) from 11 populations, listed below alphabetically by their 3-letter labels. Five of the ten ENCODE 3 regions overlap with the HapMap-ENCODE regions; the other five are regions selected at random from the ENCODE target regions (excluding the 10 HapMap-ENCODE regions). All ENCODE 3 regions are 100-kb in size, and are centered within each respective ENCODE region. The HapMap 3 and ENCORE 3 data are downloadable from the ftp site.
Proper citation: HapMap 3 and ENCODE 3 (RRID:SCR_004563) Copy
http://toc.lbg.ac.at/en/research-program/project-tumor-bank
As a basis for the experimental cluster projects, and for further future projects a collection of various biological specimens of cancer patients shall be established. All participating Ludwig Boltzmann Institutes (LBIs) are supplying biological specimens from tumor patients and clinical documentation. At the LBI for Gynecology and Gynecologic Oncology a tumor bank for biological specimens from gynecologic cancer patients already exists. All the procedures for sample processing and storage are well established. Existing equipment for storing tissue specimens at -196 degrees C can be used. Materials from the following malignant diseases are collected: Breast cancer Colorectal cancer Neuroendocrine tumors (NET) (Small cell lung cancer (SCLC) and Carcinoid tumors) Types of biological materials: Tissue (fresh frozen) Bone marrow Blood (serum/plasma/cell fractions) Pleural effusions Ascitic fluids Sputum Bronchial lavage Stool The biological specimens are initially processed at the respective LBIs or at their connected lab facilities. Enrichment of blood samples for disseminated tumor cells is done at the LBI for Gynecology and Gynecologic oncology. Long time storage of all materials is done at appropriate temperatures at the same institution. This LBI also coordinates the logistics. All relevant sample-specific and clinical data are surveyed at the respective LBIs and stored centralized in an on-line data bank in anonymized form, respecting all relevant regulations on data protection and security.
Proper citation: Ludwig Boltzman Tumour Bank (RRID:SCR_004322) Copy
Established in 1970, the University of Miami Tissue Bank (UMTB) is the oldest academic institution of its kind in the United States. UMTB came about and evolved in an effort to provide safe and effective bone and soft tissue grafts to patients long before allograft bone transplantation was widely accepted. UMTB has always been focused on safety and the advancement of knowledge in allograft use. More scientific peer-reviewed articles, book chapters and innovations have come from UMTB either directly or indirectly than from any other organization of its kind. UMTB continues to be a leader in transplantation research and has maintained an impeccable safety record. As the only university-run tissue bank, UMTB works closely with surgeons and basic science investigators to advance the field of bone and soft tissue transplantation. Our scientific endeavors include clinical trials to confirm and improve graft efficacy for oral surgery, orthopedic tumor and spine surgery, and sports injuries. When warranted, we engage commercial entities for these studies. As a multidisciplinary organization of surgeons, pathologists, scientists and technicians, we have safely recovered, processed, distributed and implanted aseptically processed bone, cartilage and soft tissue grafts in thousands of patients. We make extraordinary efforts to ensure aseptic recovery and processing to protect the biologic activity, integrity, bio attributes, and safety of the graft. We believe that the American Association of Tissue Banks (AATB) has adopted appropriate guidelines for Tissue Banking in the United States and the University of Miami is a proud member of this organization.
Proper citation: University of Miami Tissue Bank (RRID:SCR_004560) Copy
The Center for Organ Recovery & Education (CORE) is one of 58 federally designated agencies in the United States known as a not-for-profit organ procurement organization (OPO). CORE is dedicated to promoting donation, education and research for the purpose of saving and improving the quality of life through organ, tissue and corneal transplantation. An innovative, responsive OPO, CORE plays a pivotal role between potential donors and patients awaiting transplantation. In addition to talking with families about the opportunity to donate, CORE coordinates the surgical recovery of organs, tissue and corneas, as well as the computerized matching of donated organs and placement of corneas. In 1995, CORE created the first donor card database in Pennsylvania. In 1996, the organization added tissue recovery and eye banking services to its organ recovery component. It enhanced its line of services by opening an internal laboratory in 1997, where CORE performs the necessary tests to help determine if the organs, tissue and corneas are healthy for transplantation. Since its inception more than 30 years ago, CORE has helped to provide more than 300,000 organs, tissue and corneas for transplantation. The chances for renewed health provided through CORE would not be possible without those who have said yes to donation.
Proper citation: Center for Organ Recovery and Education - CORE (RRID:SCR_004317) Copy
Established in 1987, LifeGift is a not-for-profit organ procurement organization that recovers organs and tissue for individuals needing transplants in 109 Texas counties in North, Southeast and West Texas. Our Role * Help grieving families consider the decision to give the gift of life. Inform families of registered donors of their loved ones����?? wishes to donate. * Coordinate the organ and tissue recovery process with surgeons, other transplant professionals and transplant centers. Collect data for use in transplantation research. * Partner with hospitals to continually develop effective, government-regulated donation systems to help increase the number of donated organs available for transplant. * Educate the public about the need for organ and tissue donation. Serve the African-American, Latino and Asian minority communities with specific educational programs. * Continue to support and maintain contact with donor families following the donation process, facilitating communication between recipients and donor families, if both parties desire.
Proper citation: LifeGift Organ Donation Center (RRID:SCR_004555) Copy
http://allograftinnovations.com/
Allograft Innovations was formed in 2006 to facilitate quality biologic grafts for surgery. We are committed to providing quality tissue to enhance patients'' health, mobility and quality of life nationwide and across the globe. Our goal is to provide the safest, most clinically effective allografts available. The health of tissue recipients is top priority to us, and we take every possible step to ensure safety and integrity during all processes. Allograft Innovations partners with federally designated OPO''s (Organ Procurement Organization), as well as Tissue recovery agencies that comply with all 21 CFR 1270 and 1271 FDA Standards, and have achieved AATB accreditation.
Proper citation: Allograft Innovations, LLC (RRID:SCR_004435) Copy
http://ehs.sph.berkeley.edu/holland/biorepository/
Established in 2004, SPH Biorepository was built to create a centralized facility for many research programs, as well as for new ones; more effective use of the available storage space; development of new database management tools; and quality control of sample processing and banking. While maintaining ultimate control of the samples accumulated in their research projects, PIs will have the assurance of competent handling of their biological samples, reliable access, safe storage, and expert advice from the Biorepository personnel. In the long-term, the Biorepository will provide: * Safe and orderly storage of banked samples * Samples diversification in case of a major disaster *Leverage for additional funding for the new projects Over 145,000 thousands of various biological and environmental samples have been stored and archived through the CHAMACOS, Vitamin, FACES, IBD, and other projects. The Biorepository (Holland - Director) has accumulated substantial expertise in the development of customized databases to barcode and monitor sample location, transfer, and use.
Proper citation: SPH Biorepository (RRID:SCR_004551) Copy
http://www.bionet.umn.edu/tpf/home.html
Procure and distribute human tissue and other biological samples in support of basic, translational, and clinical cancer research at the University of Minnesota. The TPF is a centralized resource with standardized patient consent, sample collection, processing, storage, quality control, distribution, and electronic record maintenance. Since the 1996 inception of the TPF, over 61,000 tissue samples including well-preserved samples of malignant and benign tumors, organ-matched normal tissue, and other types of diseased tissues, have been collected from surgical specimens obtained at the University of Minnesota Medical Center-Fairview (UMMC-F) University Campus. Surgical pathologists are intellectually engaged in TPF functions, providing researchers with specimen-oriented medical consultation to facilitate research productivity. Prior to surgery, TPF personnel identify and consent patients for procurement of tissue, blood, urine, saliva, and ascites fluid. Within the integrated working environment of the surgical pathology laboratory, freshly obtained tissues not needed for diagnosis are selected and provided by pathologists to TPF personnel. Tissue samples are then assigned an independent code and processed. TPF staff can also work with researchers to individualize the procurement of tissues to fit specific research needs.
Proper citation: University of Minnesota Tissue Procurement Facility (RRID:SCR_004270) Copy
To meet the strategic objectives of ongoing and future scientific and medical research, Biostor Ireland designed and constructed a technologically advanced repository for storage and distribution of biological materials. It offers secure, certified realtime biostorage of valuable biological materials for medical / scientific research, healthcare, medical device, pharmaceutical and biopharmaceutical sectors. This facility has been inspected by the Irish Medicines Board (IMB) and complies with the requirements of the EU Directive 2004/23/EU for storage and distribution of Human Tissues and Cells. Biostor also complies with the principals of current Good Manufacturing Practice (GMP), FDA requirements 21 CFR Part 1271 and ISBER (International Society of Biological and Environmental Repositories) Best Practices for Repositories. Outsourcing biostorage makes sense * Increase Workspace * Reduce Storage Costs * Peace of Mind * Expand your Business * Reduce Labor Costs * Uniform Maintenance * Improve Productivity * Tailored Storage * Delegate
Proper citation: Biostor Ireland (RRID:SCR_004428) Copy
http://www.nimhans.kar.nic.in/neuropathology/neuropath2.htm#brainbank
A National Facility to promote research in Neurobiology using human nervous tissues. The brain tissues collected with informed consent of close relatives within 4-24 hours following death are frozen for Biochemical, Immuno-histochemical and Molecular Biological studies. A large number of formalin fixed brain tissues from various Neurological, Neurosurgical and Psychiatric disorders are also available for study.
Proper citation: Bangalore Brain Bank (RRID:SCR_004227) Copy
http://www.communitytissue.org/
Community Tissue Services (CTS), a not-for-profit tissue bank, was founded in Dayton, Ohio in 1986 as a division of the Community Blood Center. The tissue bank was established to help patients in need of life saving or life enhancing tissue grafts. CTS'' goal is to educate the community of the importance of tissue donation so that families can make informed decisions about the options of donation. CTS serves the public through recovery, processing and distribution of human tissue grafts used for transplantation. Since 1994, CTS has expanded its Dayton, Ohio operations into Texas, Oregon, California, Indiana, Pennsylvania and Tennessee, with over 300 employees nationwide. CTS is an accredited member of the American Association of Tissue Banks and CTS-CTIR is ISO 13485 certified. Strongly committed to providing the highest quality of tissues for transplantation, the tissue bank complies with all federal and state regulations. CTS is currently one of the largest US tissue banks, distributing nearly 10% of the tissue grafts in the United States. CTS is the largest nonprofit provider of skin grafts to surgeons for severe burn patients.
Proper citation: Community Tissue Services - CTS (RRID:SCR_004582) Copy
http://tissuebank.stanford.edu/
The Stanford Tissue Bank was established with seed funding from the Bio-X Program and the Department of Pathology, and currently receives support from the Stanford Cancer Institute. The goal of the Tissue Bank is to facilitate biomedical research using tissues at Stanford, by providing services for the procurement, storage, distribution, and study of tissues. Current Tissue Bank activities and services include collecting and banking freshly-frozen tissue specimens from excess surgical material and from autopsy, providing fresh tissue specimens for viable cell studies, processing and banking blood components, maintaining a tissue database with links to clinicopathological data, performing histological staining and pathological review, and coordinating patient consent and assuring regulatory compliance. As a centralized shared resource, the Tissue Bank adds value through experience, efficiency, standardization, accountability, protection of patient confidentially, and timely completion of research. An oversight committee serves to guide policies, prioritize resources, and review service requests to ensure equitable usage.
Proper citation: Stanford Tissue Bank (RRID:SCR_004615) Copy
http://www.albertahealthservices.ca/services.asp?pid=service&rid=2044
The Southern Alberta Organ and Tissue Donation Program is an integrated donation program for organs, occular tissue and non-occular tissue. These services are provided by the Southern Alberta Organ Donation Program, Lions Eye Bank & the Southern Alberta Tissue Program. This service provides: * coordination of donation, allocation, recovery and distribution of organs for transplantation for Southern Alberta; * recovery, processing, storage and distribution of occular and non-occular tissues for transplantation; * public , professional education and awareness; * research and statistics; * bereavement support.
Proper citation: Southern Alberta Organ and Tissue Donation Program (RRID:SCR_004577) Copy
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