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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://livercenter.ucsf.edu/cell-biology-core
Core whose purpose is providing primary and immortalized liver cells for experimental use as well as other material such as human liver cells, primary hepatocytes, and immortalized cell lines.
Proper citation: UCSF Liver Center Cell Biology Core (RRID:SCR_015600) Copy
http://www.uchicagoddrcc.org/research-cores/integrated-translational-research-core
Core that serves as both a central repository for all the samples and data shared by the other cores and a catalyst for interdisciplinary research.
Proper citation: University of Chicago Digestive Diseases Research Core Center Integrated Translational Research Core (RRID:SCR_015606) Copy
Encyclopedia of white and brown adipocyte secretome in mouse models and humans as key prerequisite to elucidating role of these mediators in normal physiology and disease.
Proper citation: Secrepedia (RRID:SCR_022590) Copy
https://github.com/FunctionalUrology/SpheroScan
Software tool for analyzing images of spheroids. Designed to streamline process of spheroid segmentation, area calculation, and downstream analysis of spheroid image data, and can help to standardize and accelerate analysis of spheroid assay results.
Proper citation: SpheroScan (RRID:SCR_023886) Copy
https://cran.rstudio.com/web/packages/accucor/index.html
Software as isotope natural abundance correction algorithm that is needed especially for high resolution mass spectrometers. Natural abundance correction of mass spectrometer data.
Proper citation: AccuCor (RRID:SCR_023046) Copy
https://github.com/compbiolabucf/APA-Scan
Software Python tool for detection and visualization of annotated and potential alternative polyadenylation events in downstream 3'-UTR of gene among two different biological conditions. Used for detection and visualization of 3'-UTR alternative polyadenylation with RNA-seq and 3'-end-seq data.
Proper citation: APA-Scan (RRID:SCR_022974) Copy
https://generanger.maayanlab.cloud/gene/A2M?database=ARCHS4
Web server application that provides access to processed data about expression of human genes and proteins across human cell types, tissues, and cell lines from several atlases. Used to explore single gene expression across tissues and cell types.
Proper citation: GeneRanger (RRID:SCR_023622) Copy
https://targetranger.maayanlab.cloud/
Web server application that identifies targets from user inputted RNA-seq samples collected from cells we wish to target. By comparing inputted samples with processed RNA-seq and proteomics data from several atlases, TargetRanger identifies genes that are highly expressed in target cells while lowly expressed across normal human cell types, tissues, and cell lines.
Proper citation: TargetRanger (RRID:SCR_023621) Copy
https://crispresso.pinellolab.partners.org/submission
Software suite of tools to qualitatively and quantitatively evaluate outcomes of genome editing experiments in which target loci are subject to deep sequencing and provides integrated, user friendly interface. Used for analysis of CRISPR-Cas9 genome editing outcomes from sequencing data. CRISPResso2 provides accurate and rapid genome editing sequence analysis.Used for analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments.
Proper citation: CRISPResso (RRID:SCR_021538) Copy
http://www.type2diabetesgenetics.org/
Portal and database of DNA sequence, functional and epigenomic information, and clinical data from studies on type 2 diabetes and analytic tools to analyze these data. .Provides data and tools to promote understanding and treatment of type 2 diabetes and its complications. Used for identifying genetic biomarkers correlated to Type 2 diabetes and development of novel drugs for this disease.
Proper citation: Accelerating Medicines Partnership Type 2 Diabetes Knowledge Portal (AMP-T2D) (RRID:SCR_003743) Copy
https://www.proteinspire.org/MOPED/
An expanding multi-omics resource that enables rapid browsing of gene and protein expression information from publicly available studies on humans and model organisms. MOPED also serves the greater research community by enabling users to visualize their own expression data, compare it with existing studies, and share it with others via private accounts. MOPED uniquely provides gene and protein level expression data, meta-analysis capabilities and quantitative data from standardized analysis utilizing SPIRE (Systematic Protein Investigative Research Environment). Data can be queried for specific genes and proteins; browsed based on organism, tissue, localization and condition; and sorted by false discovery rate and expression. MOPED links to various gene, protein, and pathway databases, including GeneCards, Entrez, UniProt, KEGG and Reactome. The current version of MOPED (MOPED 2.5) The current version of MOPED (MOPED 2.5, 2014) contains approximately 5 million total records including ~260 experiments and ~390 conditions.
Proper citation: MOPED - Model Organism Protein Expression Database (RRID:SCR_006065) Copy
Research center for hematology research. It provides services through four scientific core facilities: the Experimental Mouse Resources Core, the Optical Microscopy Services Core, the Angiogenesis Core, and the Flow Cytometry Core in addition to the Enrichment Program of the Center.
Proper citation: Indiana University Cooperative Center of Excellence in Hematology (RRID:SCR_015343) Copy
http://zfrhmaps.tch.harvard.edu/cemh/
Research center investigating molecular hematology through mouse and zebrafish models.
Proper citation: Boston Children's Hospital Center of Excellence in Molecular Hematology (RRID:SCR_015348) Copy
http://www.cumc.columbia.edu/derc/
Research center which provides research support for investigators pursuing research on diabetes and metabolic disorders.
Proper citation: Columbia Diabetes Research Center (RRID:SCR_015075) Copy
http://hms-dbmi.github.io/scde/index.html
Software package that implements a set of statistical methods for analyzing single-cell RNA-seq data, including differential expression analysis (Kharchenko et al.) and pathway and geneset overdispersion analysis (Fan et al.)
Proper citation: SCDE (RRID:SCR_015952) Copy
http://www.cfrc.pitt.edu/index.html
Research center whose goal is to understand and translate the basic mechanisms of cystic fibrosis. It uses the molecular and cell biology of CFTR, CFTR mutants, infection, and inflammation with the overall theme of translating preclinical science into clinical investigations.
Proper citation: Cystic Fibrosis Center University of Pittsburgh (RRID:SCR_015400) Copy
Center that includes over seventy investigators engaged in basic and translational research in diabetes and related metabolic disorders, and their complications. It contains four Research Cores that serve for innovative and translational research.
Proper citation: Indiana Diabetes Research Center (RRID:SCR_015080) Copy
Network helps to organize and support collaborative research related to loss of functional beta cell mass in Type 1 Diabetes (T1D). Project consists of four independent research initiatives: Consortium on Beta Cell Death and Survival (CBDS), Consortium on Human Islet Biomimetics (CHIB), Consortium on Modeling Autoimmune Interactions (CMAI), Consortium on Targeting and Regeneration (CTAR), and Human Pancreas Analysis Program (HPAP).
Proper citation: Human Islet Research Network (HIRN) (RRID:SCR_014393) Copy
http://www.einstein.yu.edu/centers/diabetes-translational-research/timc/
Core facility that supports research that addresses the prevention and control of diabetes using a social-ecological approach to address the dynamic interrelations of biological, psychological and social factor at a personal and environmental level.
Proper citation: New York Regional Center for Diabetes Translation Research Translational Intervention Methodology Core (RRID:SCR_015180) Copy
Core that provides Liver Research Center investigators an extensive array of customized viral and non-viral vectors, viral and non-viral vectors for reprogramming somatic cells, generating special non-viral vectors, consultation for study design and, if appropriate, data analysis.
Proper citation: Marion Bessin Liver Research Center Genetic Engineering and Gene Therapy (RRID:SCR_015186) Copy
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