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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PeakSeq
 
Resource Report
Resource Website
10+ mentions
PeakSeq (RRID:SCR_005349) PeakSeq software resource A software program for identifying and ranking peak regions in ChIP-Seq experiments. It takes as input, mapped reads from a ChIP-Seq experiment, mapped reads from a control experiment and outputs a file with peak regions ranked with increasing Q-values. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Yale University; Connecticut; USA
PMID:19122651 biotools:peakseq, OMICS_00453 https://bio.tools/peakseq SCR_005349 2026-09-19 12:50:52 39
Anne O'Tate
 
Resource Report
Resource Website
1+ mentions
Anne O'Tate (RRID:SCR_005340) Anne O'Tate service resource A web based search tool to help you gain an overview of the set of articles (up to 25,000 most recent articles) retrieved by a PubMed query. Once you enter a query, you can select different types of summary information to view: Important words, Topics, Authors, Affiliations, Journals, Year, Clustered by topic. database is listed by: OMICtools
is related to: PubMed
has parent organization: University of Illinois at Chicago; Illinois; USA
PMID:18279519 OMICS_01171 SCR_005340 2026-09-19 12:50:51 2
GEM
 
Resource Report
Resource Website
10+ mentions
GEM (RRID:SCR_005339) GEM software resource Java software for studying protein-DNA interaction using ChIP-seq / ChIP-exo data. It links binding event discovery and motif discovery with positional priors in the context of a generative probabilistic model of ChIP data and genome sequence, resolves ChIP data into explanatory motifs and binding events at unsurpassed spatial resolution. GEM reciprocally improves motif discovery using binding event locations, and binding event predictions using discovered motifs. chip-seq, chip-exo, genome, event, motif, protein-dna interaction, java, transcription factor, genome sequence, motif discovery, binding event calling is listed by: OMICtools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
PMID:22912568 OMICS_00441 SCR_005339 Genome wide Event finding and Motif discovery, GEM: ChIP-Seq and ChIP-exo analysis tool 2026-09-19 12:50:51 12
Hiclib
 
Resource Report
Resource Website
10+ mentions
Hiclib (RRID:SCR_005535) Hiclib software resource An Software resource is listed by: OMICtools OMICS_00521 SCR_005535 2026-09-19 12:50:55 22
SHRiMP
 
Resource Report
Resource Website
100+ mentions
SHRiMP (RRID:SCR_005496) SHRiMP software resource A software package for aligning genomic reads against a target genome. next generation sequencing, alignment is used by: Jambalaya
is listed by: OMICtools
is related to: Jambalaya
is related to: Proovread
has parent organization: University of Toronto; Ontario; Canada
PMID:21278192 OMICS_00685 SCR_005496 SHRiMP - SHort Read Mapping Package 2026-09-19 12:50:54 208
SMALT
 
Resource Report
Resource Website
500+ mentions
SMALT (RRID:SCR_005498) SMALT software resource Software that aligns DNA sequencing reads with a reference genome. Reads from a wide range of sequencing platforms, for example Illumina, Roche-454, Ion Torrent, PacBio or ABI-Sanger, can be processed including paired reads. is listed by: OMICtools
is related to: Sequence Search and Alignment by Hashing Algorithm
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
OMICS_00686 SCR_005498 2026-09-19 12:50:54 516
TIGRFAMS
 
Resource Report
Resource Website
100+ mentions
TIGRFAMS (RRID:SCR_005493) JCVI TIGRFAMS, TIGRFAM data or information resource, data set, database Consists curated multiple sequence alignments, Hidden Markov Models (HMMs) for protein sequence classification, and associated information designed to support automated annotation of (mostly prokaryotic) proteins. Starting with release 10.0, TIGRFAMs models use HMMER3, which provides excellent search speed as well as exquisite search sensitivity. See the "TIGRFAMs Complete Listing" page to review the accession, protein name, model type, and EC number (if assigned) of all models. TIGRFAMs is a member database in InterPro. The HMM libraries and supporting files are available to download and use for free from our FTP site. sequence alignment, hidden markov model, protein sequence, classification, protein, protein family, sequence homology, sequence, homology, function, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: InterPro
is related to: InterPro
has parent organization: J. Craig Venter Institute
PMID:23197656 Free nif-0000-03560, OMICS_01700, biotools:tigrfams https://bio.tools/tigrfams http://www.tigr.org/TIGRFAMs SCR_005493 TIGRFAMs 2026-09-19 12:50:54 142
Segemehl
 
Resource Report
Resource Website
10+ mentions
Segemehl (RRID:SCR_005494) Segemehl software resource A software to map short sequencer reads to reference genomes. It is able to detect not only mismatches but also insertions and deletions. Furthermore, it is not limited to a specific read length and is able to mapprimer- or polyadenylation contaminated reads correctly. segemehl implements a matching strategy based on enhanced suffix arrays (ESA). Segemehl now supports the SAM format, reads gziped queries to save both disk and memory space and allows bisulfite sequencing mapping and split read mapping. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: ANNOgesic
has parent organization: University of Leipzig; Saxony; Germany
PMID:24512684
PMID:22581174
PMID:19750212
DOI:10.1371/journal.pcbi.1000502
Acknowledgement requested, Free, Public biotools:segemehl, OMICS_00683 https://bio.tools/segemehl, https://sources.debian.org/src/segemehl/ SCR_005494 segemehl - short read mapping with gaps 2026-09-19 12:50:54 48
PASS
 
Resource Report
Resource Website
1000+ mentions
PASS (RRID:SCR_005490) PASS software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 19, 2020.A program to align short sequences that has been developed with an innovative strategy to perform fast gapped and ungapped alignment onto a reference sequence. It supports several data formats and allows the user to modulate very finely the sensitivity of the alignments. The program is designed to handle huge amounts of short reads generated by ILLUMINA, SOLiD and Roche-454 technology. The optimization of the internal data structure and a filter based on precomputed short-word alignments allow the program to skip false positives in the extension phase, thus reducing the execution time without loss of sensitivity. The final alignment is performed by dynamic programming., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: PASS-bis
has parent organization: University of Padua; Padua; Italy
PMID:19218350 THIS RESOURCE IS NO LONGER IN SERVICE biotools:pass, OMICS_00673 https://bio.tools/pass SCR_005490 PASS: a program to align short sequences 2026-09-19 12:50:54 2085
Fulcrum
 
Resource Report
Resource Website
1+ mentions
Fulcrum (RRID:SCR_005523) Fulcrum software resource Software to collapse identical and near-identical Illumina and 454 reads (such as those from PCR clones) into single error-corrected sequences; it can process paired-end as well as single-end reads. Fulcrum is customizable and can be deployed on a single machine, a local network or a commercially available MapReduce cluster, and it has been optimized to maximize ease-of-use, cross-platform compatibility and future scalability. Sequence datasets have been collapsed by up to 71%, and the reduced number and improved quality of the resulting sequences allow assemblers to produce longer contigs while using less memory. illumina, 454, read, paired-end read, single-end read, high-throughput sequencing, redundant read, genome, transcriptome, ultra high throughput sequencing is listed by: OMICtools
has parent organization: Stanford University School of Medicine; California; USA
PMID:22419786 BSD-like license OMICS_01049 http://pringlelab.stanford.edu/protocols.html SCR_005523 Fulcrum Read Collapser 2026-09-19 12:50:55 4
Maq
 
Resource Report
Resource Website
50+ mentions
Maq (RRID:SCR_005485) Maq software resource A set of programs that map and assemble fixed-length Solexa/SOLiD reads in a fast and accurate way. command-line, curses/ncurses, opengl, c, c++, perl, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: SourceForge
DOI:10.1101/gr.078212.108 GNU General Public License, v2 OMICS_00668, biotools:maq https://bio.tools/maq, https://sources.debian.org/src/maq/ SCR_005485 mapass2, Mapping and Assembly with Quality, Mapping and Assembly with Qualities, Maq: Mapping and Assembly with Qualities 2026-09-19 12:50:54 74
MOSAIK
 
Resource Report
Resource Website
50+ mentions
MOSAIK (RRID:SCR_005486) MOSAIK software resource A reference-guided assembler comprising of two main modular programs: MosaikBuild and MosaikAligner. MosaikBuild converts various sequence formats into Mosaik?s native read format. MosaikAligner pairwise aligns each read to a specified series of reference sequences and produces BAMs as outputs. At this time, the workflow consists of supplying sequences in FASTA, FASTQ, Illumina Bustard & Gerald, or SRF file formats and producing results in the BAM format. Unlike many current read aligners, MOSAIK produces gapped alignments using the Smith-Waterman algorithm. MOSAIK is written in highly portable C++ and currently targetted for the following platforms: Microsoft Windows, Apple Mac OS X, FreeBSD, and Linux operating systems. Other platforms can easily be supported upon request. MOSAIK is multithreaded. If you have a machine with 8 processors, you can use all 8 processors to align reads faster while using the same memory footprint as when using one processor. MOSAIK supports multiple sequencing technologies. In addition to legacy technologies such as Sanger capillary sequencing, our program supports next generation technologies such as Roche 454, Illumina, AB SOLiD, and experimental support for the Helicos Heliscope. next-generation sequencing, alignment, smith-waterman algorithm, c++, computational biology, reference guided aligner is listed by: OMICtools
is listed by: Debian
is related to: 1000 Genomes: A Deep Catalog of Human Genetic Variation
has parent organization: Google Code
Free, Freely available OMICS_00669 https://sources.debian.org/src/mosaik-aligner/ SCR_005486 mosaik-aligner 2026-09-19 12:50:54 87
MACE
 
Resource Report
Resource Website
1000+ mentions
MACE (RRID:SCR_005520) MACE software resource A bioinformatics tool dedicated to analyze ChIP-exo data: 1) Sequencing depth normalization and nucleotide composition bias correction. 2) Signal consolidation and noise reduction. 3) Single base resolution border detection. 4) Border matching. is listed by: OMICtools
has parent organization: SourceForge
OMICS_00520 SCR_005520 MACE: Model based Analysis of ChIP-exo 2026-09-19 12:50:55 1192
NextGenMap
 
Resource Report
Resource Website
100+ mentions
NextGenMap (RRID:SCR_005488) NGM software resource A mapping program for Next Generation Sequencing reads that is more than twice as fast as BWA, while achieving a mapping sensitivity similar to Stampy or Bowtie2. NextGenMap uses a memory efficient index structure (hash table) to store the positions of all 13-mers present in the reference genome. This index enables a quick identification of potential mapping regions for every read. Unlike other methods, NextGenMap dynamically determines for each read individually how many of the potential mapping regions have to be evaluated by a pairwise sequence alignment. Moreover, NextGenMap uses fast SIMD instructions (SSE) to accelerate the alignment calculations on the CPU. If available NextGenMap calculates the alignments on the GPU (using OpenCL/CUDA) resulting in a runtime reduction of another 20 - 50 %, depending on the underlying data set. next-generation sequencing is listed by: OMICtools
has parent organization: University of Vienna; Vienna; Austria
OMICS_00672 SCR_005488 Nextgenmap - A mapping method for Next Generation Sequencing reads 2026-09-19 12:50:54 179
ea-utils
 
Resource Report
Resource Website
100+ mentions
ea-utils (RRID:SCR_005553) ea-utils software resource Command-line software tools for processing biological sequencing data. Barcode demultiplexing, adapter trimming, etc. Primarily written to support an Illumina based pipeline - but should work with any FASTQs. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.2174/1875036201307010001 MIT License OMICS_01041, biotools:ea-utils https://bio.tools/ea-utils, https://sources.debian.org/src/ea-utils/ SCR_005553 ea-utils: FASTQ processing utilities 2026-09-19 12:50:55 289
BSeQC
 
Resource Report
Resource Website
1+ mentions
BSeQC (RRID:SCR_005428) BSeQC software resource A quality control software package specially for bisulfite sequencing experiments. It can comprehensively evaluate the quality of BS-seq experiments and automatically trim nucleotides with potential technical biases. In addition, BSeQC also support removing duplicate reads and keeping one copy of the overlapping segment in paired-end sequencing. bisulfite sequencing, bisulfite, sequencing is listed by: OMICtools Artistic License, GNU General Public License OMICS_00572 SCR_005428 BSeQC: Quality Control of bisulfite sequencing experiments 2026-09-19 12:50:53 6
NGSQC
 
Resource Report
Resource Website
100+ mentions
NGSQC (RRID:SCR_005459) NGSQC software resource Software pipeline that provides a set of novel quality control measures for quickly detecting a wide variety of quality issues in deep sequencing data derived from two dimensional surfaces, regardless of the assay technology used. It also enables researchers to determine whether sequencing data related to their most interesting biological discoveries are caused by sequencing quality issues. NGSQC can help to ensure that biological conclusions, in particular those based on relatively rare sequences, are not caused by low quality sequencing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. next generation sequencing, quality control is listed by: OMICtools
has parent organization: University of Michigan; Ann Arbor; USA
PMID:21143816 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01064 SCR_005459 Next Generation Sequencing Quality Control, NGSQC: Next Generation Sequencing Quality Control 2026-09-19 12:50:53 129
MSC
 
Resource Report
Resource Website
MSC (RRID:SCR_005450) MSC software resource A classification software for DNA methylation profiling with bisulphite next-generation sequencing data. classification, dna methylation, bisulfite, next-generation sequencing, methylation, r is listed by: OMICtools PMID:24273245 OMICS_00610 SCR_005450 Methylation Status Calling 2026-09-19 12:50:53 0
MLML
 
Resource Report
Resource Website
1+ mentions
MLML (RRID:SCR_005449) MLML software resource A software tool to simultaneously estimate hydroxymethylation (5hmC) and methylation (5mC) levels from BS-seq, oxBS-seq and TAB-seq experiments. It generates consistent estimates across experiment types. is listed by: OMICtools
has parent organization: University of Southern California; Los Angeles; USA
OMICS_00609 SCR_005449 2026-09-19 12:50:53 7
MethylExtract
 
Resource Report
Resource Website
10+ mentions
MethylExtract (RRID:SCR_005446) MethylExtract software resource A user friendly software tool to generate i) high quality, whole genome methylation maps and ii) to detect sequence variation within the same sample preparation. bisulfite sequencing, methylation map, methylation, sequence variation, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Granada; Granada; Spain
Acknowledgement requested biotools:methylextract, OMICS_00605 https://bio.tools/methylextract SCR_005446 High-Quality methylation maps and SNV calling from BS-Seq experiments 2026-09-19 12:50:53 14

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