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The REasons for Geographic and Racial Differences in Stroke (REGARDS) project, sponsored by the National Institutes of Health (NIH), is a national study focusing on learning more about the factors that increase a person''s risk of having a stroke. REGARDS is an observational study of risk factors for stroke in adults 45 years or older. 30,239 participants were recruited between January 2003 and October 2007. They completed a telephone interview followed by an in-home physical exam. Measurements included traditional risk factors such as blood pressure and cholesterol levels, and an echocardiogram of the heart. At six month intervals, participants are contacted by phone to ask about stroke symptoms, hospitalizations and general health status. The study is ongoing and will follow participants for many years. The purpose of the REGARDS project is to understand why people in some parts of the country develop more strokes than people in other parts of the country, and why blacks develop more strokes than whites. We hope to learn how to reduce the number of people having strokes.
Proper citation: REGARDS - REasons for Geographic and Racial Differences in Stroke (RRID:SCR_007228) Copy
Bone Marrow Donors Worldwide (BMDW) is the continuing effort to collect the HLA phenotypes of volunteer stem cell donors and cord blood units, and is responsible for the co-ordination of their worldwide distribution. Participants are 63 stem cell donor registries from 44 countries, and 43 cord blood banks from 25 countries. The current number of donors and cord blood units in the BMDW database is: 14,605,618 (14,178,976 donors and 426,642 CBU''s The original goal to collect the HLA phenotypes of volunteer stem cell donors and cord blood units, and to co-ordinate their world-wide distribution remain their primary goals. But new initiatives have been added: - To maximise the chance of finding a stem cell donor or cord blood unit by providing access to all stem cell donors and cord blood units available in the world. - To minimise the effort required for stem cell donor or cord blood unit searches: only registries with potential stem cell donors or cord blood units need to be contacted. - To provide an estimate of the chance of finding a stem cell donor or cord blood unit for a given patient. - To provide advanced search programs to identify partially matched stem cell donors or cord blood units. - To facilitate search advice requests via the Internet. - To facilitate improvements in family search strategies. - To provide relevant general information for the benefit of the patient. - To provide statistics on the increase of different registries, the number of DNA typed donors, etc. Sponsors: Bone Marrow Donors Worldwide is an initiative of the Immunobiology Working Party of the European Group of Blood and Marrow Transplantation (EBMT) in 1988. Keyworss: Bone marrow, Donor, Cell, Phenotype, Stem cell, Cord blood unit,
Proper citation: Bone Marrow Donors Worldwide (RRID:SCR_007186) Copy
Welcome to CPAN, where you you will find All Things Perl. CPAN is the Comprehensive Perl Archive Network, a large collection of Perl software and documentation. You can begin exploring from either http://www.cpan.org/, http://www.perl.com/CPAN/ or any of the mirrors listed at http://www.cpan.org/SITES.html. Note that CPAN is also the name of a Perl module, CPAN.pm, which is used to download and install Perl software from the CPAN archive. This FAQ covers only a little about the CPAN module and you may find the documentation for it by using perldoc CPAN via the command line or on the web at http://search.cpan.org/dist/CPAN/lib/CPAN.pm. Sponsors: CPAN works with the generosity and cooperation of hundreds of developers, over 100 participating mirrors, funet.fi donating the network bandwidth, storage space and computing power, volunteers who help keep everything together and users whose interest in Perl keep the archive alive and growing. Keywords: Comprehension, Perl, Archive, Software, Documentation,
Proper citation: Comprehensive Perl Archive Network (RRID:SCR_007253) Copy
http://www.ebi.ac.uk/Tools/emboss/cpgplot/indexhtml
This portal allows for the detection of regions of genomic sequences that are rich in the CpG pattern is important because such regions are resistant to methylation and tend to be associated with genes which are frequently switched on. Regions rich in the CpG pattern are known as CpG islands. The function of the program cpgplot is to plot CpG rich areas, and cpgreport to report all CpG rich regions. The nuclear genomes of vertebrates are mosaics of isochores, very long stretches of DNA that are homogeneous in base composition and are compositionally correlated with the coding sequences that they embed. Isochores can be partitioned in a small number of families that cover a range of GC levels. Program isochore plots GC content over a sequence. Sponsors: This resource is supported by European Bioinformatics Institute. Keywords: Software, Plotting, Pattern, CpG, Gene, Function, Isochore, DNA, Genome, Homogeneous, Coding, Sequence, Family, Sequencing,
Proper citation: EMBOSS CpGPlot/CpGReport/Isochore (RRID:SCR_007254) Copy
http://cardiogenomica.altervista.org/CARDIOGENOMICS/CardioGenomics%20Homepage.htm
The primary goal of the CardioGenomics PGA is to begin to link genes to structure, function, dysfunction and structural abnormalities of the cardiovascular system caused by clinically relevant genetic and environmental stimuli. The principal biological theme to be pursued is how the transcriptional network of the cardiovascular system responds to genetic and environmental stresses to maintain normal function and structure, and how this network is altered in disease. This PGA will generate a high quality, comprehensive data set for the functional genomics of structural and functional adaptation of the cardiovascular system by integrating expression data from animal models and human tissue samples, mutation screening of candidate genes in patients, and DNA polymorphisms in a well characterized general population. Such a data set will serve as a benchmark for future basic, clinical, and pharmacogenomic studies. Training and education are also a key focus of the CardioGenomics PGA. In addition to ongoing journal clubs and seminars, the PGA will be sponsoring symposia at major conferences, and developing workshops related to the areas of focus of this PGA. Information regarding upcoming events can be found in the Events section of this site, and information about training and education opportunities sponsored by CardioGenomics can be found on the Teaching and Education page. The CardioGenomics project came to a close in 2005. This server, cardiogenomics.med.harvard.edu, remains online in order to continue to distribute data that was generated by investigators under the auspices of the CardioGenomics Program for Genomic Applications (PGA). :Sponsors: This resource is supported by The National Heart, Lung and Blood Institute (NHLBI) of the NIH., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: CardioGenomics (RRID:SCR_007248) Copy
http://www.genes2cognition.org/
A neuroscience research program that studies genes, the brain and behavior in an integrated manner, established to elucidate the molecular mechanisms of learning and memory, and shed light on the pathogenesis of disorders of cognition. Central to G2C investigations is the NMDA receptor complex (NRC/MASC), that is found at the synapses in the central nervous system which constitute the functional connections between neurons. Changes in the receptor and associated components are thought to be in a large part responsible for the phenomenon of synaptic plasticity, that may underlie learning and memory. G2C is addressing the function of synapse proteins using large scale approaches combining genomics, proteomics and genetic methods with electrophysiological and behavioral studies. This is incorporated with computational models of the organization of molecular networks at the synapse. These combined approaches provide a powerful and unique opportunity to understand the mechanisms of disease genes in behavior and brain pathology as well as provide fundamental insights into the complexity of the human brain. Additionally, Genes to Cognition makes available its biological resources, including gene-targeting vectors, ES cell lines, antibodies, and transgenic mice, generated for its phenotyping pipeline. The resources are freely-available to interested researchers.
Proper citation: Genes to Cognition: Neuroscience Research Programme (RRID:SCR_007121) Copy
http://www-sequence.stanford.edu/group/candida/
The Stanford Genome Technology Center began a whole genome shotgun sequencing of strain SC5314 of Candida albicans. After reaching its original goal of 1.5X mean coverage of the haploid genome (16Mb) in summer, 1998, Stanford was awarded a supplemental grant to continue sequencing up to a coverage of 10X, performing as much assembly of the sequence as possible, using recognizable genes as nucleation points. Candida albicans is one of the most commonly encountered human pathogens, causing a wide variety of infections ranging from mucosal infections in generally healthy persons to life-threatening systemic infections in individuals with impaired immunity. Oral and esophogeal Candida infections are frequently seen in AIDS patients. Few classes of drugs are effective against these fungal infections, and all of them have limitations with regard to efficacy and side-effects.
Proper citation: Sequencing of Candida Albicans (RRID:SCR_013437) Copy
http://www.physci.ucla.edu/research/GomezPinilla/
We are interested on the mechanisms by which environmental factors affect neuronal health. We have found that trophic factors endogenous to the brain and spinal cord can be induced by the practice of select behaviors. We have recently reported that physical activity, learning, and nutritional factors control neurotrophins in the brain. These findings opened the exciting possibility that regulation of trophic factors by behavior can be a pivotal mechanism by which specific experiences can impact the structure and function of the CNS. It may account for the improvement of CNS function after trauma provided by rehabilitative therapies. On the contrary, it may explain the decay in function in aging or degenerative diseases following a lack of stimulation. These two avenues provide direction for my research program: 1) How trophic factors induced by activity can help functional recovery following brain and spinal cord trauma. We are using several exercise models to boost the production of trophic factors in the brain and spinal cord. Our goal is to provide critical information to guide the design of behavioral therapies for the reduction of the severity of insult or disease, and to increase CNS function. 2) We are evaluating the effects of lifestyle on trophic factor production, with resulting effects on circuit remodeling, synaptic function, and cognition. We believe that changes in trophic factor as a result of select experiences can affect neuronal health with profound consequences for cognitive function. :lab :
Proper citation: Neurotrophic Lab (RRID:SCR_013572) Copy
http://orwh.od.nih.gov/cfs.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. This website endeavors to provide information on the Chronic Fatigue Syndrome Working Group (CFSWG) and its programs that is helpful to researchers, health care providers, people with CFS and their families, and the general public. :The mission of the Trans-NIH Working Group for Research on Chronic Fatigue Syndrome is to: :* Stimulate and support research on CFS within the context of the missions of all Institutes, Centers and Offices. :* Collaborate and coordinate the research agendas of all Institutes, Centers and Offices to issue on a regular basis joint Program Announcements or theme related Request for Applications to further interdisciplinary research in CFS. :* Present new knowledge to and facilitate novel theoretical approaches to CFS among NIH scientists. :* Plan and sponsor scientific symposia to foster awareness, provoke new scientific interest, and generate interdisciplinary collaboration on CFS among both the NIH and Academic medical community.
Proper citation: Chronic Fatigue Syndrome (RRID:SCR_013641) Copy
https://www.plos.org/article-level-metrics
A portal which provides access to article level metrics, PLOS news, and videos and presentations. PLOS ALMs provides altmetrics for every article published in PLOS. Researchers can stay up-to-date with their published work and share information about the impact of their publications with collaborators, funders, institutions, and the research community at large.
Proper citation: PLOS Article-Level Metrics (RRID:SCR_014022) Copy
http://hbatlas.org/pages/publications
A research paper with supplementary materials reporting the generation and analysis of exon-level transcriptome and associated genotyping data. The experiment represented both males and females of multiple ethnicities and examines gene regulation and expression in different areas of the brain. A data set on the human brain transcriptome as well as insights into the transcriptional foundations of human neurodevelopment is provided.
Proper citation: Spatio-temporal transcriptome of the human brain (RRID:SCR_013743) Copy
A web application which allows users to collect data, perform complex analyses, and generate results. Users can upload data sets from their computer or from the internet for data analysis and graph creation which can be saved, printed, and downloaded. More than 15,000 statistical data sets are available.
Proper citation: StatCrunch (RRID:SCR_013992) Copy
Collection of bioactive drug-like small molecules that contains 2D structures, calculated properties and abstracted bioactivities. Used for drug discovery and chemical biology research. Clinical progress of new compounds is continuously integrated into the database.
Proper citation: ChEMBL (RRID:SCR_014042) Copy
http://www.nitrc.org/projects/nusdast
A repository of schizophrenia neuroimaging data collected from over 450 individuals with schizophrenia, healthy controls and their respective siblings, most with 2-year longitudinal follow-up. The data include neuroimaging data, cognitive data, clinical data, and genetic data.
Proper citation: Northwestern University Schizophrenia Data and Software Tool (NUSDAST) (RRID:SCR_014153) Copy
Elixir Interoperability Platform to help people and machines to discover, access, integrate and analyse biological data. Encourages life science community to adopt standardized file formats, metadata, vocabularies and identifiers and works internationally to achieve its goals. Bioinformatics resource registry that provides scientific and technical information about analytical tools and data services for bioinformatics. Gateway to databases and tools for life science data analysis.Provides comprehensive and up-to-date catalogue of resources that are interactive and downloadable, and that offer programmatic access. The registry also allows the community to upload their own resources to the registry following a simple log in procedure.
Proper citation: ELIXIR Tools and Data Services Registry (RRID:SCR_014556) Copy
http://www.brainsimagebank.ac.uk
A searchable collection of anonymised images and associated clinical data. It includes normal individuals at all ages (from prenatal to old age). The image bank contains integrated data sets already collected as part of research studies which include control subjects. New data is added as they become available.
Proper citation: BRAINS Imagebank (RRID:SCR_014576) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 29,2025. Database built up with software and services that maintains multiple versions of terminologies, map sets, and values sets concurrently. HDD Access has superseded Concept Hub.
Proper citation: HDD Access (RRID:SCR_014581) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. This laboratory facilities contain core research space for monoclonal antibody production, oligonucleotide and peptide synthesis, gene cloning, DNA sequencing, high performance liquid chromatography, tissue culture, positron emission tomography, magnetic resonance spectroscopy and electron microscopy.
Proper citation: The Biomedical Research Foundation - Current Research (RRID:SCR_001564) Copy
VHL is a library, a decentralized and dynamic information-source collection, designed to provide equitable access to scientific knowledge on health. This collection operates as an Internet network of products and services, structured to progressively meet the need for information on health on the part of authorities, administrators, researchers, professors, students, professionals, the media and the general public. It sets itself apart from other information sources available on the Internet due to its selection criteria and quality control. The Virtual Health Library is envisioned as the broad of scientific and technical knowledge based in health-entered, organized, and stored in electronic format in the countries of the Region, universally accessible on the Internet and compatible with international databases. The VHL is a common space shared by information users, producers and intermediaries. It is based on the information paradigm set by the Internet, where users may interact with networks of information sources and with other users. The most important consequence of this paradigm is the convergence of functions and activities of production, intermediation and use of information sources. It will also be possible to enrich, schedule, reformulate, and/or translate the basic information sources into new information products and services, with value added, in order to meet more efficiently the information needs of users from specific communities. BIREME has established a plan of action to implement the Virtual Health Library based on 5 lines of action: promotion and marketing; realignment of traditional products and services; production of electronic publications; development of tools for integrating and locating information; and development of other Virtual Health Library components. Sponsors: VHL is supported by the Latin-American and Caribbean Center on Health Sciences Information.
Proper citation: Virtual Health Library (RRID:SCR_001676) Copy
http://www.neurologychannel.com/
A topical portal which provides information about conditions that affect the nervous system (brain, spinal cord, nerves, and muscles), such as stroke (brain attack), Alzheimer's disease, and back pain. It is a physician developed and monitored source of neurology information for consumers. Additionally, it contains comprehensive condition and treatment information, as well as interactive tools.
Proper citation: Neurologychannel (RRID:SCR_001597) Copy
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