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http://www.utsouthwestern.edu/research/core-facilities/obrien-kidney/core-services/animal-core.html

Core that generates and distributes several kidney-specific Cre recombinase and tetracycline-inducible activator and repressor lines to be crossed to floxed or tet responder lines provided by co-investigators.

Proper citation: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Animal Models Core (RRID:SCR_015292) Copy   

•   Source: SciCrunch Registry

http://www.utsouthwestern.edu/research/core-facilities/obrien-kidney/core-services/physiology-core.html

Core that provides measurement of serum and or urine Creatinine by Capillary Electrophoresis, measurement of serum and urine citrate by capillary electrophoresis, Microanalysis of serum and urine electrolytes by: Flame photometry, Atomic absorption or Ion-Selective Electrode, and Klotho IP-IB Assay.

Proper citation: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Physiology Core (RRID:SCR_015266) Copy   

•   Source: SciCrunch Registry

http://www.dukekidneycenter.org/cores/animal-models-core

Core facility that provides access to a range of experimental models of kidney, heart and vascular diseases. It also provides comprehensive phenotyping services for kidney functions, blood pressure and other cardiovascular functions.

Proper citation: Duke O'Brien Center for Kidney Research Animal Models Core (RRID:SCR_015267) Copy   

•   Source: SciCrunch Registry

https://digestivediseasescenters.org/content/ddrc-uab-gnotobiotic-and-genetically-engineered-mouse-core

Core facility which generates and provides gnotobiotic and genetically engineered mice to research projects. It also provides specialized breeding, marker-assisted genotyping, and histopathologic evaluation services for studies using these mice.

Proper citation: Mucosal HIV and Immunobiology Center Gnotobiotic and Genetically-Engineered Mouse Core (RRID:SCR_015263) Copy   

•   Source: SciCrunch Registry

http://www.uab.edu/medicine/hrfdcc/cores/b

Core whose goals include Generation of New Animal and Cell Models of HRFDs, to establish In Vivo Biosensors to Study Signaling Pathways Involved in HRFD Ciliopathies, and to generate and distribute HRFD Related Biologicals to the Center?s Investigator Base.

Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Engineered Models Resource (RRID:SCR_015310) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/obriencenter/cores/pre-clinical-studies-of-aki

Core that provides services such as expertise in development and training in the use of rodent models of AKI, specifically in the setting of ischemia/reperfusion (I/R) injury, sepsis and renal transplantation, gamma-ray imaging (gamma camera, microSPECT/CT, microPET/CT), metabolic assessments of kidney O2 consumption, and technical expertise in isolation of primary renal and vascular cell in culture.

Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Pre-Clinical Studies of AKI (RRID:SCR_015278) Copy   

•   Source: SciCrunch Registry

http://www.uc.edu/labs/mmpc/select-test/cardiovascular-services.html

Core that offers services in testing animal physiological variables such as blood pressure, heart rate, pulse pressure and activity after inserting a PA-C10 telemetry device in them.

Proper citation: MMPC-University of Cincinnati Medical Center Cardiovascular and Renal Function Core (RRID:SCR_015360) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org/GIConteCenter/pages/cores/integratedPhysiology.html

Core facility that provides Center investigators and their laboratories the tools and advice needed to establish and study mouse (including transgenic and knockout) and human (i.e. GI organoids) physiology of GI disease.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Integrated Physiology Core (RRID:SCR_015591) Copy   

•   Source: SciCrunch Registry

http://norc.ucsf.edu/mouse-metabolism-and-imaging-core-b

Core that provides access to instrumentation used in metabolic studies. Instruments include a 12-chambered Comprehensive Lab Animal Monitoring System (CLAMS), an EchoMRI, and dual energy X-ray absorptiometry.

Proper citation: University of California San Francisco Nutrition and Obesity Research Center Mouse Metabolism and Imaging Core (RRID:SCR_015450) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/cysticfibrosis/about/cell-model-core

Core that assists with patch clamp and single channel analysis relevant to ion channel gating. The core also provides primary murine airway epithelial cells.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cell Model and Evaluation Core (RRID:SCR_015395) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/umpc/cores/analytical/

Core that provides analysis of hormones, cytokines, chemokines, metabolites, and electrolytes across multiple platforms (serum, tissues, homogenates, and cells) as well as liver function analysis through instrumentation.

Proper citation: MMPC-University of Massachusetts Medical School Analytical Core (RRID:SCR_015365) Copy   

•   Source: SciCrunch Registry

http://www.uc.edu/labs/mmpc/select-test/lipid-metabolism.html

Core that provides services based on the testing and analysis of fat lipids, intestinal lipid absorption, and cholesterol in tissues.

Proper citation: MMPC-University of Cincinnati Medical Center Lipid Lipoprotein and Glucose Metabolism Core (RRID:SCR_015363) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=34

Core which provides services and facilities for stable, biocontainment housing, husbandry, and health care of mice. The Core manages transfer of mice from the user's institution and testing of mice for the quarantine process.

Proper citation: MMPC-University of Massachusetts Medical School Animal Care Core (RRID:SCR_015368) Copy   

•   Source: SciCrunch Registry

http://umassmed.edu/umpc/cores/cardiovascular/

Core that provides phenotyping of cardiovascular system in mouse models of metabolic disease and an easily accessible cardiovascular disease model pipeline. It services include 2D and M-mode echocardiography in lightly-anesthetized mice to non-invasively assess cardiac structure and function using state-of-the-art high-frequency, high-resolution in vivo digital imaging platform as well as Transverse Aortic Constriction (TAC) model to investigate pressure-overload hypertrophy, congestive heart failure, and aortic stenosis.

Proper citation: MMPC-University of Massachusetts Medical School Cardiovascular Core (RRID:SCR_015375) Copy   

•   Source: SciCrunch Registry

https://medicine.uiowa.edu/genetherapy/research-cores/animal-models-core

Core that provides support to investigators who use animal models to study the pathogenesis of cystic fibrosis and who develop gene and other molecular therapies for cystic fibrosis. Specifically, it provides centralized production, care, breeding, genotyping, and quality control of cystic fibrosis mouse and ferret models used by investigators in the Center.

Proper citation: University of Iowa Center for Gene Therapy Animal Model Core (RRID:SCR_015413) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=50

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2025. Core whose mission is to provide analytical tools to investigators to permit determination of the structure of the microbiome in mouse models of disease and assistance in the cultivation of microbes that will permit hypothesis testing in murine models including the germfree animals that are available in the Animal Care Core.

Proper citation: MMPC-University of Michigan Medical School Microbiome Core (RRID:SCR_015378) Copy   

•   Source: SciCrunch Registry

https://medicine.uiowa.edu/genetherapy/research-cores/comparative-pathology-core

Core facility which provides comprehensive necropsy, histology, and pathology services for animal models in order to facilitate translational research in animal models of cystic fibrosis. It also houses instrumentation which allows for high-throughput optimization of immunostaining protocols and has access to morphologic equipment that allow for the scanning of large tissue areas and morphometric quantification of histologic endpoints.

Proper citation: University of Iowa Center for Gene Therapy Comparative Pathology Core (RRID:SCR_015411) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10820/community_id/1418

Core that consists of three subcores: Hormone Assay and Analytical Services, Lipids, Lipoproteins, and Atherosclerosis, and Mouse Pathology. The Hormone Assay and Analytical Services provides analyses that facilitate research in diabetic, cardiovascular, and obese animal models. Lipids and Lipoproteins Subcore provides quantitative and qualitative measurements of plasma and tissue lipids and lipoproteins to researchers who use mice to study atherosclerosis, dyslipidemia, diabetes, obesity, hypertension, and other metabolic diseases. Mouse Pathology services include standard pathology testing in hematology, clinical chemistry, parasitology, microbiology, serology, molecular diagnostics, necropsy, and research histology and pathology expertise and counseling.

Proper citation: MMPC-Vanderbilt University School of Medicine Analytical Resources Core (RRID:SCR_015379) Copy   

•   Source: SciCrunch Registry

http://www.uc.edu/labs/mmpc/select-test/energy-balance.html

Core that specializes in total body/carcass analysis, measurement of oxygen consumption and carbon dioxide production, meal pattern analysis, and feeding mass/bouts, drinking volume, VO2 and VCO2.

Proper citation: MMPC-University of Cincinnati Medical Center Energy Metabolism Food Intake and Body Weight Regulation Core (RRID:SCR_015371) Copy   

•   Source: SciCrunch Registry

http://www.med.umich.edu/mgpc/cores/maic.htm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 8,2025. Core whose services include consultation, Nucleic Acid Isolation, Microbiome (16S) Data Analysis, MiSeq-base 16S rRNA Gene Sequencing, Genomic/Metagenomic shotgun sequencing, Bacterial transcriptomics and metatranscriptomics, Multiplatform Metabolomic Profiling, Metabolomic sample preparation, and Germ-free & Gnotobiotic Mouse Facilities.

Proper citation: University of Michigan Center for Gastrointestinal Research Microbiome and Metabolomics Core (RRID:SCR_015611) Copy   

•   Source: SciCrunch Registry