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http://jsu.eagle-i.net/i/0000012a-2505-aadb-b307-36d480000000

Core facility that provides the following services: Flow cytometry and microarray training service. The Cellomics and Toxicogenomics Research Laboratory (CTRL) has been established to provide RCMI investigators and other JSU faculty and students with state-of-the art instrumentation that would allow them to perform laser-based flow cytometric analysis and cell sorting, as well as microarray analysis of gene expression in connection to human diseases. Hence, the application of flow cytometry and modern genomic DNA microarray-based technology is providing an excellent opportunity to CTRL users to examine alterations in gene expression patterns associated with environmental exposure, as well as to study the molecular mechanisms and biochemical effects associated with cellular responses to toxic exposures.(http://www.jsums.edu/cset/rcmi/ctrl.htm)

Proper citation: JSU Cellomics and Toxicogenomics Research Core Laboratory (RRID:SCR_009889) Copy   

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http://harvard.eagle-i.net/i/0000012e-01e7-f2ed-b2b9-4d8780000000

The molecular electron microscopy facility at Harvard Medical School is predominantly used for our own research and can therefore not be considered a service facility. We are, however, committed to make our technology available to as many research groups in the community as possible. If you are interested to use molecular electron microscopy, please contact us by phone or email.

Proper citation: HMS Molecular Electron Microscopy Facility (RRID:SCR_009802) Copy   

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http://harvard.eagle-i.net/i/00000142-0084-cc9f-89f9-43eb80000000

Core facility that provides the following services: Instrument operation and data analysis.

Instrumentation for this facility includes an Agilent 6520 Accurate-Mass quadrupole time-of-flight (Q-TOF) LC/MS system with great mass accuracy, mass resolution, and sensitivity for small molecule mass identification/quantitation and metabolomics experiments. It is equipped with an Agilent 1200 series HPLC with DAD UV/V is detection for normal flow LC/MS and nitrogen CID for MS/MS. The Q-TOF LC/MS is located in laboratory of Dr. Suzanne Walker in the Department of Microbiology and Immunobiology.

Proper citation: HMS Microbiology and Immunobiology Biological Chemistry Mass Spec Facility (RRID:SCR_009800) Copy   

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http://jsu.eagle-i.net/i/0000012a-2505-e99e-b307-36d480000000

Core facility that provides the following services: Spectrofluorometry service, FTIR service, Atomic absorption spectrometry service, Raman spectrometry service, Gas chromatography service, GC/MS service, HPLC service, LC/MS/MS service, Capillary electrophoresis/mass spectrometry service, FPLC service. The Analytical Core Laboratory objectives are to: 1) provide spectroscopic and chromatographic equipment to investigators of pilot projects in the RCMI Program as well as investigators in other programs in the College of Science, Engineering and Technology for their research needs, 2) to acquire new analytical instruments as well as computers and printers to satisfy the needs of the user community, 3) to respond to the needs for obtaining analytical information in a timely manner, 4) To offer workshops for using major equipment including LC/MS/MS, CE/MS/MS, LC-ICP/MS, Raman microscope system, and FT-IR as well as other conventional instruments at least once each semester for each instrument.

Proper citation: JSU Analytical Core Laboratory (RRID:SCR_009885) Copy   

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http://harvard.eagle-i.net/i/0000012e-6e37-beec-55da-381e80000000

Core facility that provides the following services: Hematology/immunology assay service. The major objective of the Specialized Assay Core is to create greater efficiency by providing radioimmunoassays (RIAs), enzyme-linked immnosorbent assays (ELISA), bead based multiplex assays, and other basic biochemical assays to support human and animal studies performed by individual investigators at the Joslin Diabetes Center and external users who do not have access to Core Facilities. The Core allows more economic use of expensive or limited materials, provides for training of junior investigators, fosters interactions among research fellows and provides a basis for generating productive collaborative studies between institutions.

Proper citation: JDC Specialized Assay Core (RRID:SCR_009884) Copy   

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http://harvard.eagle-i.net/i/0000012e-c086-517c-cb22-be8c80000000

The main objective of the Joslin''s Media Core is to reduce the cost and labor of making tissue culture media and other reagents required by the Joslin investigators. By centralizing preparation of these reagents, the Core provides high quality reagents at a significantly reduced cost to the investigators. In addition, the Core provides services to overcome labor intensive reagent needs, like plate pouring services and preparation of specialized buffers and reagents for cell and molecular studies. The Media Core makes and provides over 10 different mammalian tissue culture media to the Joslin investigators for their studies. In addition, the Core prepares and provides several buffers and solutions to the Joslin investigators. The core also makes a variety of broths and agars for growing bacterial cultures, and provides agar plates and plate pouring service to the investigators. Over the past five years (2006-2010), by preparing and providing over 6250 liters of media and 2850 agar plates per year to the Joslin investigators the Media Core serves an important function in the efforts of these investigator to find cure for diabetes and its complications.

Proper citation: JDC Media Core (RRID:SCR_009882) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c0-1e2d-db6e-7a3f80000000

Core facility that provides the following services: Complex protein mixture analysis service, Project consultation service, Data analysis service, Protein identification service, Posttranslational modification site determination service, N-terminal Edman Sequence Analysis Service, C-terminal sequence analysis service, De novo sequence analysis service, Quantitative proteomics service, Labeled quantitative proteomics - SILAC, Labeled quantitative proteomics - ICAT service, Labeled quantitative proteomics - iTRAQ service, Labeled quantitative proteomics - AQUA service, Intact molecular weight determination service, Low resolution GC/MS service, Low resolution GC/MS/MS service, Exact mass MS & MS/MS electrospray for structural elucidation service. The FAS Center for Systems Biology Mass Spectrometry and Proteomics Resource Laboratory provides mass spectrometry and strategic consulting in Proteomics and Small Molecule analysis for Life Science and Chemistry researchers as well as others worldwide. This resource brings together the state-of-the-art expertise and instrumentation of the Microchemistry and Proteomics, CCB Mass Spectrometry, and Bauer Center Core laboratories, leveraging our breadth of experience to provide the best possible support for your research.

Proper citation: Harvard FAS Bauer Core: Mass Spectrometry and Proteomics Core Laboratory (RRID:SCR_009837) Copy   

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http://harvard.eagle-i.net/i/00000130-756e-db1e-1971-4f2080000000

Core facility that provides the following services: Nanofabrication cleanroom and instrumentation access, instrument training, staff assistance. The Center for Nanoscale Systems'' Nanofabrication Facility (CNS-NF), offers resource and staff support for fabricating and characterizing nanoscale devices and structures. The facility currently operates the 10,000 sq.ft. LISE Cleanroom with leading-edge equipment capable of electron-beam and optical lithography, physical and chemical vapor deposition, dry and wet processing, metrology, and device characterization.

Proper citation: Harvard CNS Nanofabrication Facility (RRID:SCR_009832) Copy   

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http://harvard.eagle-i.net/i/00000130-7574-3d13-1971-4f2080000000

The National Nanotechnology Infrastructure Network?s computational activity (NNIN/C) is the computational counterpart of the NNIN experimental initiative. Like the NNIN experimental program, NNIN/C is a multi-university initiative, funded by the National Science Foundation (NSF). Harvard University serves as the coordinating hub of NNIN/C, the object of which is to establish a national computing resource that provides hardware resources and simulation tools dedicated to nanoscience research for the academic and industrial research communities. Strong technical and scientific support is provided by staff experts so that the tools and resources can benefit interdisciplinary research. The software tools include commercial software packages for design, characterization and analysis of nanometer scale devices as well as some of the latest academic advances in nanoscale modeling and simulation software. The goals and strategies of NNIN/C are: * Assemble and create a wide suite of robust software that addresses critical issues related to the physical, chemical, and biological properties of artificial and natural nanoscale structures. * Maintain and, where necessary, modify these simulations to address a broad range of research problems. * Provide strong technical support and thorough instruction on the software tools so that even novice users can rapidly develop solutions to their own unique research problems. * Provide web-based graphical user interfaces (GUIs) for user-friendly access to simulation tools as well as web-based resources for instruction and feedback to the community of researchers employing the same tools

Proper citation: Harvard CNS NNIN/C Computational Facility (RRID:SCR_009830) Copy   

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https://iccb.med.harvard.edu/

Facility is small molecule and functional genomics high-throughput screening laboratory. It is built around modular work stations and most assays are performed in 384-well plates. There are over 500,000 small molecules available for screening at ICCB-Longwood and compound collection is continuously growing. Whole human and mouse genome siRNA libraries, arrayed sgRNA libraries, lncRNA siRNA libraries, as well as miRNA mimic and inhibitor libraries, are also available for screening. These libraries can be screened at the genome level or in focused subsets.

Proper citation: Harvard Medical School ICCB-Longwood Screening Core Facility (RRID:SCR_009798) Copy   

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http://harvard.eagle-i.net/i/0000012e-a18b-7386-55da-381e80000000

Characterization of mineralized tissues, natural or synthetic, is a challenging task, since these materials are comprised of organic and mineral constituents, each with strikingly different physical and chemical properties. The function of the Forsyth Mineralized Tissue Analysis (MTA) Core is to provide a comprehensive structural, physical, and chemical analysis of wild type, mutant and engineered mineralized tissues, including teeth (enamel, dentin, cementum), cartilage and bone. The strengths of the MTA Core include a unique combination of specialized instrumentation, techniques, and expertise based on more than 30 years of experience in this field.

Proper citation: Forsyth Mineralized Tissue Analysis Core Facility (RRID:SCR_009791) Copy   

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http://harvard.eagle-i.net/i/00000130-08fe-236a-de5a-673e80000000

Core facility that provides the following services: Flow cytometer equipment access, Flow cytometry consultation, Immunofluorescence analysis, Cellular sorting, Measurement of intracellular calcium signaling, DNA cell cycle analysis, Apoptosis assay service.

The purpose of this Immunology Flow Cytometry Core of the Boston Area Diabetes Endocrinology Research Center (BADERC) is to provide flow cytometric techniques in a cost effective manner to the diabetes research community. The core is committed to providing to investigators both training and a diversity of state-of-the-art flow cytometric techniques. The Core will assist investigators in applying a variety of tough and cumbersome immunologic techniques and offers in-depth training of new methods.

Proper citation: HMS BADERC Flow Cytometry Core (RRID:SCR_009792) Copy   

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http://harvard.eagle-i.net/i/00000139-68dd-9dd3-f016-703c80000000

The Forsyth Institute established the micro computed tomography core in 2011. The Facility is located in the 4th floor of the Forsyth research building. The core now accepts samples from outside academic institutions and for-profit organizations.

Proper citation: Forsyth Micro Computed Tomography (RRID:SCR_009790) Copy   

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http://harvard.eagle-i.net/i/00000130-7562-84f7-1971-4f2080000000

Center for Nanoscale Systems facility dealing with SEM, TEM, ESEM, sample prep etc.

Proper citation: Harvard CNS Imaging and Analysis Facility (RRID:SCR_009829) Copy   

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http://harvard.eagle-i.net/i/0000012e-5e87-861a-55da-381e80000000

Core for data driven projects related to basic, clinical and translational research, with a particular emphasis on diabetes. Aims to ensure that researchers take advantage of the most modern and robust methods available in the field of Bioinformatics and Biostatistics.

Proper citation: Harvard Bioinformatics Core at Joslin Diabetes Center (RRID:SCR_009827) Copy   

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http://harvard.eagle-i.net/i/0000012e-34f9-f51d-550e-f59280000000

The Exposure and Environmental Analyzes Service provides exposure assessment equipment, design of experimental apparatus, laboratory analyzes of environmental and biological samples, support for methods development and pilot data, as well as training for researchers and students. The service maintains facilities such as clean rooms and exposure chambers. Specific services are provided by the four affiliated laboratories.

Proper citation: HSPH Exposure and Environmental Analysis Service (RRID:SCR_009824) Copy   

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http://harvard.eagle-i.net/i/0000012e-352f-0669-550e-f59280000000

The EM Lab supports study relating to aerobiology. The laboratory has the capability to generate, sample, and analyze fungal, bacterial, and viral microbes.

Proper citation: HSPH Environmental Microbiology Lab (RRID:SCR_009821) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-358b-059e-550e-f59280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core provides intellectual guidance for quantitative aspects of the design and analysis of center studies and expertise in biostatistical methods, environmental risk assessment, Geographic Information System (GIS) , spatial statistics, molecular biology, bioinformatics and statistical genetics. Core runs a regular seminar series and often sponsors short courses on specialized topics of interest to the community.

Proper citation: Harvard School of Public Health Environmental Statistics and Bioinformatics Core Facility (RRID:SCR_009822) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-34e3-d4ba-550e-f59280000000

The aims of the EGS are: to assist Center investigators in preparing genomic DNA from blood/buccal swabs collected in their human population studies. This activity involves assistance in the proper collection, extraction, concentration, quality testing and hand or robotic plating for candidate gene and even Genome-Wide studies of gene-environment interaction; to assist Center investigators in creating a genomic DNA biorepository for DNA for genotyping and for epigenetics studies; to assist investigators in obtaining efficient genotyping and epigenetic services either in-house or through partner organizations in the Harvard system; and to assist Center investigators in selection of SNP''s, haplotypes, genotyping platforms and for environmental genetic and epigenetic studies of human populations.

Proper citation: HSPH Environmental Genomics Service Facility (RRID:SCR_009820) Copy   

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http://harvard.eagle-i.net/i/0000012e-a5a6-62bc-55da-381e80000000

The Biostatistics Core collaborates with clinical and laboratory investigators providing support for experimental design, statistical methods, data analysis and data management for epidemiologic studies, clinical trials and laboratory investigations. Collaborations have included Center grants, Program Projects and numerous individual investigator grants. These studies have largely focused on oral health research, particularly dental caries and periodontitis, with an emphasis on the microbial and immunologic aspects as well as diagnosis and treatment of these conditions and use of high throughput technologies in their evaluation.

Proper citation: Forsyth Biostatistics Core Facility (RRID:SCR_009784) Copy   

•   Source: SciCrunch Registry