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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on April 14,2022. Database of comprehensive information on the approximately 600 prokaryote species that are present in the human oral cavity. The majority of these species are uncultivated and unnamed, recognized primarily by their 16S rRNA sequences. The HOMD presents a provisional naming scheme for the currently unnamed species so that strain, clone, and probe data from any laboratory can be directly linked to a stably named reference entity. The HOMD links sequence data with phenotypic, phylogenetic, clinical, and bibliographic information. Full and partial oral bacterial genome sequences determined as part of this project and the Human Microbiome Project, are being added to the HOMD as they become available. HOMD offers easy to use tools for viewing all publicly available oral bacterial genomes. Data is also downloadable.
Proper citation: HOMD (RRID:SCR_012770) Copy
Open-access database of antibodies against human proteins developed through collaboration between Antibodypedia AB and the Nature Publishing Group. It aims to provide the scientific community and antibody distributors alike with information on the effectiveness of specific antibodies in specific applications--to help scientists select the right antibody for the right application. Antibodypedia's mission is to promote the functional understanding of the human proteome and expedite analysis of potential biomarkers discovered through clinical efforts. To this end, they have developed an open-access, curated, searchable database containing annotated and scored affinity reagents to aid users in selecting antibodies tailored to specific biological and biomedical assays. They envisage Antibodypedia as a virtual repository of validated antibodies against all human, and ultimately most model-organism, proteins. Such a tool will be exploitable to identify affinity reagents to document protein expression patterns in normal and pathological states and to purify proteins alone and in complex for structural and functional analyses. They hope to promote characterization of the roles and interplay of proteins and complexes in human health and disease. They encourage commercial providers to submit information regarding their inventory of antibodies with links to quality control data. Independent users can submit their own application-specific experimental data using standard validation criteria (supportive or non-supportive) developed with the assistance of an international advisory board recruited from academic research institutions. Users can also comment on specific antibodies without submitting validation data.
Proper citation: Antibodypedia (RRID:SCR_012782) Copy
https://github.com/NKI-GCF/XenofilteR
Software tool for computational deconvolution of mouse and human reads in tumor xenograft sequence data.
Proper citation: XenofilteR (RRID:SCR_026196) Copy
https://www.skinresearch.northwestern.edu/cores/stem-core.html
Core provides services in human skin tissue procurement, isolation, and culture of human and murine skin-derived primary cells, 3D organotypic skin cultures, tissue processing, and basic histologic stains. The Core trains researchers in the development and use of these various techniques.
Proper citation: Northwestern University School of Medicine SBDRC Skin Tissue Engineering and Morphology Core Facility (RRID:SCR_026414) Copy
https://bioconductor.org/packages/release/data/experiment/html/dorothea.html
Software R package for storing the regulons. Gene regulatory network containing signed transcription factor (TF) - target gene interactions. DoRothEA regulons, the collection of TF and its transcriptional targets, were curated and collected from different types of evidence for both human and mouse. Confidence level was assigned to each TF-target interaction based on number of supporting evidence.
Proper citation: DoRothEA (RRID:SCR_027126) Copy
https://www.augusta.edu/mcg/pathology/research/index.php
Core offers pathology services to prepare and stain animal and human tissue for basic and clinical research.
Proper citation: Augusta University Medical College of Georgia Pathology Research Services Core Facility (RRID:SCR_027309) Copy
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