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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Hollings Cancer Center Tissue Biorepository and Research Pathology Services Shared Resource
 
Resource Report
Resource Website
1+ mentions
Hollings Cancer Center Tissue Biorepository and Research Pathology Services Shared Resource (RRID:SCR_004626) HCC Tissue Biorepository cell repository, material resource, biomaterial supply resource The Hollings Cancer Center Tissue Biorepository & Research Pathology Services Shared Resource provides investigators with a centralized infrastructure that promotes biomedical research involving the use and study of human biospecimens. The shared resource is comprised of four integrated components: Biospecimens and data bank, Laser Capture Microdissection, Tissue Microarray, and Research Pathology Services. These components, along with extensive staff expertise, offer a comprehensive means by which researchers can utilize valuable human biospecimens and cutting edge technology to support basic, translational and clinical research. Services: * Biospecimen and Data Bank ** Collecting, processing, and banking of tissue, saliva, urine, blood, plasma, serum, and other tissue derivatives; including those for protocol driven studies ** Retrieval of banked specimens linked to clinicopathologic data, while maintaining patient confidentiality, for research use ** Quality control of collected tissue by the Tissue Biorepository Director, a trained pathologist: verification of diseased state and assessment of tumor purity, etc ** Quality control of DNA/RNA/protein isolated from collected tissue using the Agilent Bioanalyzer * Laser Capture Microdissection ** Identification, localization, and microdissection of targeted cell populations (from human and animal tissue sources) ** Extraction of DNA/RNA/protein from microdissected samples. ** Quality analysis and quality control of isolated nucleic acid using Agilent Bioanalyzer * Tissue Microarray ** Create custom and standard TMAs ** Consultation and technical support in the construction and analyses of TMA * Research Pathology Services ** Macrodissection of tissue prior to isolation of DNA/RNA/protein to increase tumor purity ** Immunohistochemistry and In-situ hybridization ** Quantitative image analysis on conventional and TMA sections, including tissue scoring, Ki-67 labeling index, microvascular density counting, and tissue microarray scoring, etc. * Bio-molecular Assessment ** Cellular DNA, RNA and protein prepared by the Tissue Repository from banked specimens or any other biomolecules submitted by investigators can be qualitatively assessed by Agilent Bioanalyzer, prior to use for downstream applications such as microarray and/or qRT-PCR analysis cancer, leukemia, lymphoma, myeloma, solid tumor, tumor, tissue, saliva, urine, blood, plasma, serum, dna, rna, protein, clinicopathologic data, immunohistochemistry, in-situ hybridization, macrodissection, tissue microarray, paraffin, frozen, oct embedded, block, h & e staining, slide, malignant, bodily fluid is listed by: One Mind Biospecimen Bank Listing
has parent organization: Medical University of South Carolina; South Carolina; USA
Cancer, Leukemia, Lymphoma, Myeloma, Solid tumor, Tumor Public: Prices listed for HCC, MUSC, And outside MUSC. nlx_62775 http://hcc.musc.edu/research/sharedresources/biorepository/index.htm SCR_004626 Hollings Cancer Center Tissue Biorepository Research Pathology Services Shared Resource 2026-08-04 09:41:11 2
STRAP
 
Resource Report
Resource Website
100+ mentions
STRAP (RRID:SCR_005675) STRAP data processing software, software application, software resource Software program that automatically annotates a protein list with information that helps in the meaningful interpretation of data from mass spectrometry and other techniques. It takes protein lists as input, in the form of plain text files, protXML files (usually from the TPP), or Dat files from MASCOT search results. From this, it generates protein annotation tables, and a variety of GO charts to aid individual and differential analysis of proteomics data. It downloads information from mainly the Uniprot and EBI QuickGO databases. STRAP requires Windows XP or higher with at least version 3.5 of the Microsoft .NET Framework installed. Platform: Windows compatible protein, gene, annotation, mass spectrometry, proteomics, visualization, browser, differential analysis, analysis, ontology or annotation browser, ontology or annotation visualization, differential analysis of proteomics data sets, windows, protein annotation, data visualization, c#, pathway, FASEB list is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: UniProt
is related to: QuickGO
has parent organization: Boston University School of Medicine; Massachusetts; USA
NHLBI contract N01 HV28178;
NCRR P41 RR10888
PMID:19839595 Open unspecified license, Acknowledgement requested OMICS_02277, nlx_149115 SCR_005675 Software Tool for Rapid Annotation of Proteins, STRAP for GO Annotation, STRAP - Software Tool for Rapid Annotation of Proteins 2026-08-04 09:41:25 120
Washington University Basic Local Alignment Search Tool
 
Resource Report
Resource Website
1000+ mentions
Washington University Basic Local Alignment Search Tool (RRID:SCR_008285) data processing software, software application, software resource It is used to compare a novel sequence with those contained in nucleotide and protein databases by aligning the novel sequence with previously characterized genes. evolutionary, fragment, function, functional, gene, genetic code, algorithm, align, alignment, blast, local, novel, nucleotide, pair, protein, region, segment, sensitivity, sequence, similarity, structure, tool has parent organization: European Molecular Biology Laboratory nif-0000-23905 SCR_008285 WU-BLAST2 2026-08-04 09:42:07 3631
Integrated Biobank of Luxembourg
 
Resource Report
Resource Website
1+ mentions
Integrated Biobank of Luxembourg (RRID:SCR_004211) IBBL biomaterial supply resource, material resource, tissue bank An independent, not-for-profit biobanking and biotechnology foundation designed to facilitate new, high quality medical research. The IBBL collects, stores, and analyzes biological samples and associated data, which are then made available to research organizations investigating new treatments for diseases. It houses a biospecimen collection and biorepository that contains high quality tissues and maintains quality control of the specimens and the clinical data associated with the tissue samples, while maintaining biobanking ethical standards. It also provides biorefinery analyses and research services that can make analytes from tissues (e.g. DNA, RNA and protein), maintains technology for high throughput gene sequencing and gene expression, and conducts biospecimen research. An informatics platform maintains the clinical and biospecimens data in a secure fashion for additional analysis. Samples are collected by IBBL personnel from hospitals in a targeted manner. The IBBL collaborates with research and health organizations in North America, Europe and the Middle East, and with the major international biobanking societies. biobank, biorepository, clinical data, tissue, dna, rna, protein, cancer, type 2 diabetes, parkinsons disease, biotechnology is listed by: One Mind Biospecimen Bank Listing Cancer, Type 2 diabetes, Parkinson's disease Public nlx_23314 SCR_004211 2026-08-04 09:41:05 5
UCL/UCLH Biobank for Studying Health and Disease
 
Resource Report
Resource Website
UCL/UCLH Biobank for Studying Health and Disease (RRID:SCR_004610) UCL Biobank for studying Health and Disease biomaterial supply resource, material resource, tissue bank The UCL/UCLH Biobank for Studying Health and Disease has been primarily established to support the Research Programme and scientific needs, of the Pathology Department UCLH & the UCL Cancer Institute. The establishment of the core programme enables a centralised approach to the management and integration of all research groups working within these institutions, providing appropriate structure and support. The biobank has policies and guidelines to guarantee compliance with HTA legislation and to ensure quality standards will be maintained. The biobank stores normal and pathological specimens, surplus to diagnostic requirements, from relevant tissues and bodily fluids, as well as human tissue used in xenograft experiments. Stored tissues include; snap-frozen or cryopreserved tissue, formalin-fixed tissue, paraffin-embedded tissues, and slides prepared for histological examination. Tissues include resection specimens obtained surgically or by needle core biopsy. Bodily fluids include; whole blood, serum, plasma, urine, cerebrospinal fluid, milk, saliva and buccal smears and cytological specimens such as sputum and cervical smears. Fine needle aspirates obtained from tissues and bodily cavities (eg. pleura and peritoneum) are also collected. Where appropriate the biobank also stores separated cells, protein, DNA and RNA isolated from collected tissues and bodily fluids described above. Some of the tissue and aspirated samples are stored in the diagnostic archive. specimen, pathology, tissue, bodily fluid, human tissue, xenograft, tissue, blood, serum, plasma, urine, cerebral spinal fluid, milk, saliva, buccal smear, sputum, cervical smear, pleura, peritoneum, cell, protein, dna, rna, snap-frozen, cryopreserved, formalin-fixed, paraffin-embedded, slide, normal, disease, cancer, frozen is listed by: One Mind Biospecimen Bank Listing
has parent organization: University College London; London; United Kingdom
Normal, Disease, Cancer Private / Partners: The aim is to support primarily, Research in the Pathology Department, UCLH and the UCL-Cancer Institute but it will also support other UCLH partners. nlx_143838 SCR_004610 UCL/UCLH Biobank for Studying Health Disease, UCL Biobank for studying Health Disease, UCL / UCLH Biobank for Studying Health Disease 2026-08-04 09:41:10 0
AutoEVM
 
Resource Report
Resource Website
AutoEVM (RRID:SCR_017556) data processing software, software application, software resource Software tool as Autorun Evidence Modeler. Requires EVidenceModeler (aka EVM) software which combines ab into gene predictions and protein and transcript alignments into weighted consensus gene structures. Autorun, Evidence, Modeler, gene, prediction, protein, transcript, elignment, weighted, gene, structure Free, Available for download, Freely available SCR_017556 Autorun EVidence Modeler 2026-08-04 09:44:11 0
HOLLOW
 
Resource Report
Resource Website
10+ mentions
HOLLOW (RRID:SCR_005729) HOLLOW data processing software, data visualization software, software application, software resource HOLLOW facilitates the production of surface images of proteins. HOLLOW is a portable command-line utility written in Python 2.4-2.7; it does not have any other dependencies (although running under the PyPy JIT interpreter, it runs much faster). The input is a PDB file. The output is a PDB file of dummy water atoms that forms a cast of the voids and channels of a protein. HOLLOW generates a surface from a cast of the protein surface. HOLLOW fills the interior spaces of a protein structure with dummy atoms defined on an overlapping grid. The surface generated by these dummy atoms can be shown to reproduce the surface of the protein at the ideal limit. The use of the surface of the dummy atoms allows us to focus on a specific piece of the interior surface. Simply by deleting dummy atoms, the interior surface can be trimmed to produce a custom portion of the interior space. For advanced coloring of the surface, the B-factor of the dummy atoms can be calculated as the average of the B-factor of the protein atoms surrounding the dummy atoms. This allows various colorings of the surface to be conveyed through the B-factor field of the PDB files. The volume filling representation facilitated by HOLLOW is meant to complement other programs that identify voids, pockets and channels, such as SPHGEN and CASTp, which identify binding sites but cannot produce output that can be rendered in standard molecular graphics software. HOLLOW can be used to help render these binding pockets. surface image, protein, protein image, protein structure, image, channel surface, electrostatic surface, interior pathway surface, ligand-binding surface, molecular structure, python is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: University of California at San Francisco; California; USA
has parent organization: SourceForge
Center for Membrane Protein Structure ;
Membrane Protein Expression Center ;
Howard Hughes Medical Institute
PMID:19014592 nlx_149186 SCR_005729 HOLLOW - Volume Filling of Protein Structures, HOLLOW: Generating Accurate Representations of Channel and Interior Surfaces in Molecular Structures 2026-08-04 09:41:26 37
PONDR
 
Resource Report
Resource Website
50+ mentions
PONDR (RRID:SCR_023691) data access protocol, software resource, web service Web tool to predict order and disorder from amino acid sequence. Used to predict of natural disordered regions in proteins. amino acid sequence, predict sequence order and disorder, protein natural disordered regions prediction, protein, NLM R01 LM06916;
NSF ;
DOE ;
MRC of Canada
DOI:10.1016/S1093-3263(00)00138-8 Free, Freely available SCR_023691 Predictor of Natural Disordered Regions 2026-08-04 09:45:19 90
FuzDrop
 
Resource Report
Resource Website
10+ mentions
FuzDrop (RRID:SCR_023675) data access protocol, software resource, web service Web tool to predict probability of proteins to undergo liquid-liquid phase separation.Used to perform sequence based identification of both droplet promoting regions and of aggregation promoting regions within droplets. Used to predict droplet promoting regions and proteins, which can spontaneously phase separate. protein, liquid-liquid phase separation, separation prediction, sequence based identification, droplet promoting regions, aggregation promoting regions, is related to: UniProtKB Hungarian Academy of Sciences PMID:33318217 Free, Freely available SCR_023675 2026-08-04 09:45:19 15
ToRNADo
 
Resource Report
Resource Website
50+ mentions
ToRNADo (RRID:SCR_002706) data processing software, data visualization software, software application, software resource A software application for animating and visualising RNA and other macromolecular structures. Users are able to use their intuition to interactively refold RNA structures and produce morphs from one structure to another. It allow researchers to explore and manipulate molecular structures Imported from BiositeMaps registry, to better understand structure:function relationships, folding pathways, and molecular motion. duplex, protein, rna, visualization has parent organization: Stanford University; Stanford; California NIH ;
NIGMS R01GM107340;
NIGMS U54GM072970
Free, Available for download, Freely available nif-0000-23335 SCR_002706 2026-08-04 09:40:43 95
National Resource for the Mass Spectrometric Analysis of Biological Macromolecules
 
Resource Report
Resource Website
National Resource for the Mass Spectrometric Analysis of Biological Macromolecules (RRID:SCR_009007) National Resource for the Mass Spectrometric Analysis of Biological Macromolecules biomedical technology research center, training resource Biomedical technology research center that develops cutting-edge mass spectrometric tools for analyzing peptides and proteins. It makes its software tools developed for data analysis freely available. systems biology technology center, mass spectrometric, analysis, peptide, protein, software, proteomic, cellular function has parent organization: Rockefeller University; New York; USA NIGMS nlx_152683 SCR_009007 2026-08-04 09:42:15 0
eXpression2Kinases
 
Resource Report
Resource Website
1+ mentions
eXpression2Kinases (RRID:SCR_016307) X2K software application, software resource Software tool to produce inferred networks of transcription factors, proteins, and kinases predicted to regulate the expression of the inputted gene list by combining transcription factor enrichment analysis, protein-protein interaction network expansion, with kinase enrichment analysis. It provides the results as tables and interactive vector graphic figures. inferred, network, transcription, factor, protein, kinase, regulate, expression, gene, analysis, combine, bio.tools is listed by: Debian
is listed by: bio.tools
NIGMS P50 GM071558;
NIDDK R01 DK088541;
NLM RC2 LM010994;
NIDDK P01 DK056492;
NIDDK RC4DK090860;
NCRR KL2 RR029885
PMID:22080467 Open source, Free, Freely available, Available for download biotools:x2k https://bio.tools/x2k, http://www.maayanlab.net/X2K/ SCR_016307 eXpression2Kinases, X2K 2026-08-04 09:43:52 4
Batch Entrez
 
Resource Report
Resource Website
10+ mentions
Batch Entrez (RRID:SCR_016634) software application, software resource Software program for loading numbers of genome records. Allows the retrieval of a large number of nucleotide sequences or protein sequences, in a batch mode, by importing a file containing a list of the desired GI or accession numbers. load, number, genome, record, retrieval, nucleotide, sequence, protein, batch, mode has parent organization: NCBI
works with: Entrez
Public, Free, Freely available SCR_016634 2026-08-04 09:43:57 47
Aline
 
Resource Report
Resource Website
1+ mentions
Aline (RRID:SCR_016886) software application, software resource Software interactive perl/tk application which can read common sequence alignment formats which the user can then alter, embellish, markup etc to produce the kind of sequence figure commonly found in biochemical articles. Extensible WYSIWYG protein sequence alignment editor for publication quality figures. protein, sequence, alignment, editor, publication, quality, alter, embellish, markup, biochemistry, bioinformatics is related to: University of Dundee; Scotland; United Kingdom
is related to: University of Western Australia; Perth; Australia
PMID:19390156 Free, Available for download, Freely available SCR_016886 2026-08-04 09:44:00 2
DOMAINATRIX
 
Resource Report
Resource Website
DOMAINATRIX (RRID:SCR_016084) software application, software resource Software for protein domain search. It is a part of Embassy software package. protein, domain, search, molecular, biology is listed by: Debian Free, Available for download, Freely available http://emboss.sourceforge.net/what/, https://sources.debian.org/src/embassy-domainatrix/ SCR_016084 Embassy-domainatrix 2026-08-04 09:43:48 0
e-Driver
 
Resource Report
Resource Website
1+ mentions
e-Driver (RRID:SCR_002674) software application, standalone software, software resource Software tool to identify cancer driver genes based on linear annotations of biological regions such as protein domains.Uses information on three-dimensional structures of mutated proteins to identify specific structural features. Then algorithm analyzes whether these features are enriched in cancer somatic mutations and are candidate driver genes. Identify cancer driver genes, candidate driver genes, perl, protein, mutated proteins, cancer somatic mutations, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Cancer PMID:25064568 Free, Available for download, Freely available biotools:e-Driver, OMICS_05288 https://bio.tools/e-Driver SCR_002674 2026-08-04 09:40:42 5
TraDES
 
Resource Report
Resource Website
1+ mentions
TraDES (RRID:SCR_006142) TraDES software application, software resource With Trajectory Directed Ensemble Sampling (TraDES) create large ensembles of high-quality protein structures quickly, ranging from near-native to partially unfolded to intrinsically unfolded. TraDES is a system for directly controlling and sampling protein conformational space. TraDES has been previously used for measuring the vastness of protein conformational space and testing the hypothesis of a brute force solution to the protein folding problem. Over 10 Billion protein structures have been produced by TraDES software in previous distributed computing experiments. The package is comprised of binary executable programs and accessory programs and scripts as well as protein structure data files that map out protein conformational space in a probabilistic way. The main programs are: * trades - generates protein structures following the Trajectory Distribution (see below) * seq2trj - makes Trajectory Distributions from sequences for sampling * str2tr - makes Trajectory Distributions from 3D structures for sampling Trajectory Distributions - Controlling the Sampling of Conformational Space The concept of the trajectory distribution may be new to many protein scientists. A trajectory distribution is simply a map of available conformational space at an amino acid residue. NMR scientists are the primary users of the TraDES package. protein, protein structure, structure, trajectory, sequence, protein folding has parent organization: Christopher Hogues Research Lab at the National University of Singapore PMID:11746699
PMID:10737933
Open-source nlx_151632 SCR_006142 Trajectory Directed Ensemble Sampling, TraDES - Trajectory Directed Ensemble Sampling 2026-08-04 09:41:31 6
MapMan
 
Resource Report
Resource Website
1000+ mentions
MapMan (RRID:SCR_003543) MapMan software application, software resource Software tool that displays large genomics datasets (e.g. gene expression data from Arabidopsis Affymetrix arrays) onto diagrams of metabolic pathways or other biological processes. metabolic pathway, biological process, genomics, pathway, array, visualization, gene, transcript, protein, enzyme, metabolite is related to: GoMapMan
has parent organization: Max Planck Institute of Molecular Plant Physiology; Golm; Germany
PMID:19389052
PMID:14996223
PMID:16009995
PMID:16649112
nlx_157682 SCR_003543 MapMan Application Software 2026-08-04 09:40:56 1225
GPCR Network
 
Resource Report
Resource Website
GPCR Network (RRID:SCR_014286) data or information resource, data repository, project portal, portal, database, storage service resource, service resource A protein family specific platform that works closely with the GPCR community to determine the high resolution structure and function of GPCRs. Structures are available in the glutamate, secretin, frizzled/TAS2, adhesion, and rhodopsin branches of the protein phylogenetic tree. Users can access a list of protein structure targets and completed protein structures. protein family structure platform, high resolution structure, gprc, function, glutamate, secretin, frizzled/TAS2, adhesion, rhodopsin, protein has parent organization: University of Southern California; Los Angeles; USA PMID:23237917 Public, Open data SCR_014286 2026-08-05 10:46:07 0
Mascot
 
Resource Report
Resource Website
5000+ mentions
Mascot (RRID:SCR_014322) data processing software, signal processing software, software application, standalone software, software resource A software package and server used to identify and characterize proteins from primary sequence databases using mass spectrometry data. Mascot integrates peptide mass fingerprinting, sequence querying, and MS/MS ion searching in order to search for proteins in databases like SwissProt, NCBInr, EMBL EST divisions, contaminants, and cRAP. If a license is purchased, users may: search data sets that exceed the 1200 spectrum limit of the free version; set up automated, high throughput work; add and edit proteins and quantification methods; and search a preferred collection of sequence databases. The software package works with instruments from AB Sciex, Agilent, Bruker, Jeol, Shimadzu, Thermo Scientific, and Waters. server, software package, mass spectrometry, protein, identify, characterize, bio.tools is used by: MSQuant
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: MascotScan
Free, Can be licensed for in-house use, Available for download biotools:MASCOT http://www.matrixscience.com/search_intro.html, https://bio.tools/MASCOT SCR_014322 Mascot Server 2026-08-05 10:46:07 6896

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