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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.georgiahealth.edu/cancer/shared/tumor/index.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. The MCG Tumor Tissue and Serum Repository or tumor bank, located in the Department of Pathology, Murphey Pathology Building, was established with support from the Georgia Cancer Coalition (GCC). Its mission is to provide researchers access to high quality annotated specimens, an essential requirement for cancer research. The repository collection includes a variety of specimen types, such as tumor tissue and cells, blood and other biofluids as well as normal specimens used as controls. The quality of all specimens is reviewed by a pathologist, and the information is captured in the tumor bank''s database. An imaging system will be used in the future to capture this information. Human-derived specimens are a very precious resource, and therefore the operations of the tumor bank are overseen by an advisory board, representing GHSU and other stakeholders, to ensure that the specimens are properly utilized and the privacy of specimen donors is protected.
Proper citation: Medical College of Georgia Tumor Bank (RRID:SCR_004336) Copy
http://www.bloodandtissue.org/
The Blood and Tissue Center of Central Texas is a 501(c)(3) not-for-profit organization. Its mission is to safeguard the community''s gifts of blood and tissue with uncompromising quality and excellence in customer service. The Center is licensed by the US Food and Drug Administration, accredited by the American Association of Blood Banks and American Association of Tissue Banks, and is a proud member of America''s Blood Centers. The Blood and Tissue Center today is the exclusive provider and guardian of the community blood supply for more than 37 medical facilities in a ten-county service area of Central Texas. In 2010, over 56,000 whole blood donations and 7,700 apheresis platelet donations were collected. These donations are tested extensively to assure suitability for transfusion and processed into life saving components: red blood cells, plasma, and platelets, which go to help Central Texas patients. The Center works with the Marrow Donor Program of Central and South Texas to increase the number of Central Texans on the National Marrow Donor Registry. The Tissue Services division was established in 1985 due to the increasing demand for allograft tissue. Today, The Tissue Center surgically recovers tissue from approximately 300 donors each year and assists with donor family services. The Tissue Center''s main facility is located in Austin with a satellite office in Corpus Christi.
Proper citation: Blood and Tissue Center of Central Texas (RRID:SCR_004578) Copy
http://www.tumorbank.unibe.ch/
Tumorbank Bern - TBB collects high quality clinical samples since 2003 for translational research selected by expert pathologists under controlled conditions of normal and diseased tissue from different origin. The Tumor Bank is approved by the Ethical Commission of Bern, we only collect samples with written informed patient consent. Origin of Tissue: Thoracic Surgery, Gynecology, Urology, Visceral Surgery, Orthopedic Surgery, Head and Neck Surgery, Neurosurgery Tumorbank Bern TBB holds 12,000 samples from 3600 Patients. Please contact us to check if we have samples for your field of research.
Proper citation: Tumorbank Bern (RRID:SCR_004611) Copy
Donor Network of Arizona is the federally designated, not-for-profit, organ procurement organization for the state of Arizona and a tissue and eye recovery organization. DNA serves five organ transplant centers in Arizona with the combined capacity to perform heart, lung, kidney, pancreas and liver transplants. * Our Mission: We make the most of life through the gift of organ and tissue donation. * Our Vision: We challenge ourselves and others everyday to realize Arizona''s potential to save and improve lives. DNA shares organs regionally and nationally through the United Network for Organ Sharing''s (UNOS) national network. DNA is accredited by the Association of Organ Procurement Organization, American Association of Tissue Banks and the Eye Bank Association of America.
Proper citation: Donor Network of Arizona (RRID:SCR_004330) Copy
http://www.walescancerbank.com/
The Wales Cancer Bank aims to collect samples of tumour, normal tissue and blood from all patients in Wales who are undergoing an operation to remove tissue where cancer is a possible diagnosis. These samples will be banked to build up a research resource that will be used by research groups to help understand the molecular mechanisms involved in cancer and work towards the selection of optimum targeted treatment for individuals. The Wales Cancer Bank is licensed by the Human Tissue Authority (license 12107) to store human tissue for research and has ethics approval from the Wales Multicentre Research Ethics Committee to collect and issue samples for cancer related research.
Proper citation: Wales Cancer Bank (RRID:SCR_004331) Copy
http://www.m2gen.com/pages/biorepository.cfm
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The M2Gen Biorepository offers the world's largest cancer-focused tissue biobank linked to longitudinal clinical and molecular data. We provide well-annotated, high quality tissue and clinical data to support research and clinical partnerships. M2Gen's Biorepository team includes dedicated pathologists, biobanking specialists and licensed laboratory staff. Quality control assessment is performed by board-certified pathologists.
Proper citation: M2Gen Biorepository (RRID:SCR_004332) Copy
http://www.biobank-gso.org/apex/f?p=200:1:2527679222961463
The Virtual Tumour Bank of the Canceropole Grand Sud-Ouest''s mission is to federate the cancer research of four French regions: Aquitaine, Languedoc-Roussillon, Limousin and Midi-Pyrenees. This site allows access to an inventory of the specimens stored in the tumor banks of the Greater South-West region, within the laboratories of Pathology of the University Hospital Centers and Cancer Centers of Bordeaux, Limoges, Montpellier, Nimes and Toulouse. You may search by disease or multiple criteria. These specimens are removed from patients primarily to confirm and accurately characterize their cancer diagnosis, and are therefore stored by the tumor bank for diagnostic and/or therapeutic purposes. These samples can be re-qualified for scientific research pending that a number of conditions are met, including the absence of refusal from the person (in compliance with French regulations). So far, the tumor bank is a major tool for cancer treatment and research. This inventory is a further evidence of the coordination effort between the eight concerned tumor banks that have been mobilized at the service of patients and research within the framework of the Canceropole Grand Sud-Ouest programs. These biological resources are made available to research groups that conduct basic or translational programs in the field of oncology. They will not be made available for projects in fields other than oncology.
Proper citation: Southwest France Tumour Bank (RRID:SCR_004574) Copy
http://www.cornellsurgery.org/pro/services/burn-surgery/skin-bank.html
Established nearly 30 years ago, the New York Firefighters Skin Bank is the only comprehensive skin bank in New York State, providing allograft skin grafts to patients throughout the region. Allograft skin grafts enable burn victims to fight infection, maintain their fluids and body heat, and control pain. The Skin Bank also provides cryopreservation services so that patients can bank their own skin for future autologous transplantation.
Proper citation: New York Firefighters Skin Bank (RRID:SCR_004604) Copy
For 35 years, Mid-America Transplant Services (MTS) has served as the regional organ and tissue procurement organization for eastern Missouri, southern Illinois, and northeast Arkansas, serving 4.3 million people in 84 counties. From our founding goal to assist in the coordination of kidney donations, we have grown to become a multi-faceted organization dedicated to saving lives and enhancing the quality of all donated organs and tissues currently available for transplant. MTS''s primary service offering is to facilitate and coordinate the organ and tissue donation process. With a mission to save lives through excellence in organ and tissue donation, we have been at the forefront of enhancing the quality of organs and tissue for transplant. Throughout our history, we have relentlessly pursued our core values of compassion, quality, teamwork, and honesty to create a positive donation experience for Donor Families, which is at the heart of what matters most to MTS. Located in Saint Louis, Missouri, MTS is one of 58 federally designated organizations of its kind in the United States. Incorporated in the State of Missouri, MTS is a private, not-for-profit 501(c)(3). To fulfill our mission, we work closely with the four transplant centers and over 110 donor hospitals located within our service area.
Proper citation: Mid-America Transplant Services (RRID:SCR_004400) Copy
http://s213659397.onlinehome.us/lifetek.org/lifetek_Welcome.html
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. LifeTek is a full service International Tissue Bank, with recovery and processing partners in the United States, Spain and Mexico. Our goal is to provide safe, quality allograft implants, therefore serving donor families, physicians and recipients. Following regulations established by state and federal agencies, including the United States Food and Drug Administration, specific steps are taken to ensure donor suitability, including serologic testing performed by CLIA certified laboratories. LifeTek aseptically process tissues in Class 100 Cleanrooms, significantly reducing the risk of airborne contaminants. Equipment and reagents used are sterilized in steam autoclaves. Grafts are further processed and sterilized using Clearant Technology. LifeTek allografts are provided either freeze-dried or frozen. Freeze-dried allografts are stored at ambient temperatures, while frozen allografts are stored at -40 degrees C or colder. Freeze-dried allografts are provided with a maximum of two years expiration, frozen allografts are provided with a maximum of five years expiration.
Proper citation: LifeTek OrthoBiologics (RRID:SCR_004488) Copy
https://reich.hms.harvard.edu/software
Software application that finds skews in ancestry that are potentially associated with disease genes in recently mixed populations like African Americans. It can be downloaded for either UNIX or Linux.
Proper citation: Ancestrymap (RRID:SCR_004353) Copy
A provincial biobank resource to support translational cancer research at the BC Cancer Agency, across Canada and internationally. This biobank collects biospecimens (tissues and blood), and clinical information and processes these to create anonymous cases that can be studied by cancer researchers to understand how cancer develops, how it grows, how it spreads, and how it responds to treatment. These tissues and data are obtained from patients who undergo surgery to treat a tumor and who have generously provided their consent for the TTR to collect tissues that are unused after diagnosis has been completed. The TTR is a provincial program that currently comprises a core biobank at the Vancouver Island Center, Victoria, that offers participation in the program to patients in Victoria and Nanaimo. The TTR works with other banks and expert translational research groups in BC, to create expanded capacity for collection and opportunities for research access to tissue resources. The TTR operates under the management and oversight of the director, a scientific advisory board, and the UBC BCCA Research Ethics Board. The TTR operates within organizational policies and a commitment to protection of donor privacy that is embodied in all standard operating procedures and aspects of the repository. The TTR is also a founding member and contributor to the development of provincial (BC BioLibrary) and national (CTRNet) initiatives to promote biobanking.
Proper citation: British Columbia Tumour Tissue Repository (RRID:SCR_004597) Copy
http://www.nsabp.pitt.edu/NSABP_Pathology.asp
The NSABP (National Surgical Adjuvant Breast and Bowel Project) Tissue Bank is the central repository of tissue samples (stained and unstained slides, tissue blocks, and frozen tissue specimens) collected from clinical trials conducted by the NSABP. The main scientific aim of the NSABP Division of Pathology is to develop clinical context-specific prognostic markers and predictive markers that predict response to or benefit from specific therapeutic modality. To achieve this aim, the laboratory collects the tumor and adjacent normal tissues from cancer patients enrolled into the NSABP trials through its membership institutions, and maintain these valuable materials with clinical follow-up information and distribute them to qualified approved investigators. Currently, specimens from more than 90,000 cases of breast and colon cancer are stored and maintained at the bank. Paraffin embedded tumor specimens are available from NSABP trials. We currently do not bank frozen tissues. All blocks are from patients enrolled in prospective NSABP treatment protocols and complete clinical follow up information as well as demographic information is available. Depending on the project, unstained tissue sections of 4-micrometer thickness, tissue microarrays, or stained slides are provided to the investigators in a blinded study format. Any investigators with novel projects that conform to the research goals of NSABP may apply for the tissue. Please refer to the NSABP Tissue Bank Policy to determine if your project conforms to these goals. Priority is given to NSABP membership institutions who regularly submit tissue blocks.
Proper citation: National Surgical Adjuvant Breast and Bowel Project Tissue Bank (RRID:SCR_004506) Copy
At BioStorage Technologies, our mission is to provide our clients with world class, biorepository services, exceeding clients����?? expectations of service, value and quality while setting the industry standard for the storage, management & logistics of samples. Offering onsite or outsourced management of sample assets, BioStorage Technologies manages the complete life-cycle of samples. With a team of global sample experts, state-of-the-art temperature-controlled storage facilities, and a real-time web-based sample intelligence and tracking system, the company supports customers in maximizing opportunities, minimizing risk and reducing the cost of sample management. The unique advantages of BioStorage Technologies * Consulting����??Expert consulting on Good Storage Practices, global transport standards, standard operating procedures and business continuity planning to mitigate risk and optimize your resources * Consolidation����??Comprehensive management of the sample lifecycle through consolidation of sample data into one technology system for faster retrieval, more flexible tracking and enhanced security * Control����??Enhanced control of sample asset data within one technology system, ISISS, for faster go/no-go decisions and expansion into future research * Compliance����??Improved chain of custody of your samples and easier audit trail tracking for adherence to quality and regulatory compliance standards in order to support product approvals * Cost-Reduction����??Reduced cost of sample management and increased project ROI through more efficient sample and data management processes, enabling you to refocus resources on your core competencies BioStorage Technologies, Inc. was founded in 2002 and is privately held and headquartered in North America in Indianapolis, Indiana with an additional full-service site in Europe near Frankfurt, Germany.
Proper citation: BioStorage Technologies (RRID:SCR_004302) Copy
https://www.dtmi.duke.edu/for-researchers/technology-cores/duke-biobank
The Duke Biobank is an institutional resource that combines well-annotated clinical data with a standardized, regulation compliant, cost efficient repository for both fluid and tissue, connected via information systems to a large scale, long-term biobank in Kannapolis, in order to foster breakthroughs in research; while ensuring the strictest adherence to ethical standards and regulations. Our goal is to work with investigators to maintain biorepository collections which are in compliance with all relevant local, regional and national and IRB biobanking standards. Capabilities * Provide expert consultation in planning and design of biobanking programs * Access, process, aliquot, store and distribute a wide array of liquid and tissue biological samples * Maintain informatics capabilities to accurately and efficiently track samples and link to clinical and laboratory assay data * Use the Duke Biobanking Guidelines document (in development) as guidance on scientific, ethical/legal, and operational to ensure quality and standardization of biospecimen collection * Minimize redundancy of infrastructure, as appropriate, across Duke Medicine. Duke University offers both on- and off-campus options for investigators seeking biobanking services. Our biobanking facilities are: * The Center for Human Genetics (CHG). Serves as the primary on-campus biobank for liquid sample storage for Duke Medicine, and as a portal between Duke and the LabCorp Biobank. * Duke Hospital South Tissue Bank. Serves as a sample portal for the Duke Biobank, and as the primary facility for tissue storage for Duke Medicine. ** DCCC Tissue & Blood Procurement ** IGSP Biospecimen Repository * LabCorp Biorepository. Located in Kannapolis, NC, this is the preferred storage center for large-scale, infrequently accessed sample collections
Proper citation: Duke Biobank (RRID:SCR_004304) Copy
Established in 1985, LifeLink Tissue Bank is a not-for-profit organization dedicated to serving patients in need of transplantation therapy. It is one of five divisions of the LifeLink Foundation and the largest not-for-profit tissue bank in the Southeast and one of the largest in the United States. LifeLink Tissue Bank is inspected and accredited by The American Association of Tissue Banks (AATB). Our goal is to provide the safest, most clinically effective allografts while remaining cognizant of the rising cost of medical care. Donors and their families are the core of our organization. We treat them with respect, show them compassion, and offer them comfort in knowing that their confidentiality is protected and their gifts optimally utilized. Our allografts are utilized by surgeons and hospitals that trust LifeLink to provide them with safe and clinically effective allografts. Every effort is made to ensure that our allografts are placed back in the hospitals of the communities that we serve with organ and tissue recovery services.
Proper citation: LifeLink Tissue Bank (RRID:SCR_004546) Copy
http://www.ucl.ac.uk/cancer/medical-genomics/clinepi
Aims to carry out an integrated (epi)genomic analysis of the NET BioBank established at the Royal Free and UCL Hospitals to identify new biomarkers for translation into diagnostics and therapeutics. The Neuroendocrine Tumour (NET) Unit at the Royal Free Campus of UCL Hospitals has an international reputation for the management of neuroendocrine tumor patients. It currently receives around 10 new referrals per month and has an active patient cohort of over 800 patients. We receive referrals from across the UK as well as from abroad. It is the designated center for NETs within the North London Cancer Network. In order to improve both treatment and outcome in Neuroendocrine Tumors (NETs), better understanding of their biology and the biological pathways involved is imperative (reviewed in (Modlin et al., 2008)). Currently, the use of targeted treatments is limited and management challenging due to the lack of knowledge of the molecular pathogenesis and mechanistic regulation of these tumors (Barakat et al., 2004). Due to the rarity of NETs and difficulty in obtaining fresh tissue and archival samples, very little is known about the (epi)genetic and germline mutations associated with neuroendocrine tumors ����?? which encompass a clinically and genetically heterogeneous group. To date, studies have been small and under-powered. Clinical trials have included small patient numbers and are often non-randomized phase II trials comparing a new therapy against a non-standardized first line treatment. Initially we will undertake genome-wide methylation analysis on our entire cohort of neuroendocrine tumors in order to determine the methylation profiles of differing NET types. This will improve diagnostic accuracy and potentially identify new therapeutic targets and biomarkers. These studies will be performed on high-throughput analysis platforms based on micoarrays and next-generation sequencing. In parallel, we will analyze the mRNA expression profiles of these tumors to enable integrated (epi)genomic analysis of these intriguing tumors.
Proper citation: Neuroendocrine Tumors Biobank (RRID:SCR_004380) Copy
http://www.uab.edu/medicine/tcbf/sporebb-tpsfsidebar
A biomaterial supply resource which stores and provides ovarian, breast, pancreatic, and cervical tissue samples and fluids to cancer researchers. The UAB Tissue Collection and Banking Facility collects tissue samples for the UAB Ovarian, Breast, Pancreatic, and Cervix SPORE banks. Samples from the former Ovarian SPORE bank are available to UAB Cancer Center members via the Tissue Procurement Shared Facility, and to other researchers via the Cooperative Human Tissue Network.
Proper citation: UAB SPORE Biorepository Banks (RRID:SCR_004419) Copy
http://htrc.uchicago.edu/biospecimen_bank.php
Biospecimen banking (BSB) involves collecting, processing, storing and distributing of human or animal tissues and body fluids of molecular grade. Human tissues and body fluids are banked in compliance with IRB approved protocols without compromising the diagnostic process and maintaining donor confidentiality (HIPAA compliant). Investigator-driven biobanking initiatives are of paramount importance at the University. The BSB provides investigators with the infrastructure to establish organ-specific biobanks in a centralized location. This arrangement allows for minimal duplication of costs, as well as establishing a working template for all tissue collections. The BSB has grown exponentially, and has a strong team of experienced personnel banking tissues for clinical trials, investigator-driven projects, and future biospecimen-based research. In addition, the BSB now collects and stores saliva, urine, blood, plasma, serum, and derivatives. The BSB is a complex process, requiring multiple interacting systems to ensure the scientific quality of procured tissue, and body fluids, patient confidentiality, adherence to good clinical practices, and regulated disbursement of biospecimens to approved investigators. They are also aware that policies, HIPAA guidelines, and federal and state tissue procurement regulations may change, and will be fully compliant with all new regulations.
Proper citation: University of Chicago Human Tissue Resource Center Biospecimen Banking (RRID:SCR_004418) Copy
https://healthsciences.ucsd.edu/research/moores/shared-resources/biorepository/Pages/default.aspx
The Biorepository contains plasma, serum, RNA stabilized buffy coat, urine, viable tumor samples, and formalin-fixed paraffin-embedded tumor; all with associated clinical information. These can be provided to investigators with Cancer Sample Banking Committee approval (IRB approval is also required for projects requesting ongoing sample collection or clinical annotation.) Urine and blood-derived specimens are available from a wide variety of cancer cases and cancer-free controls. Tumor sample availability is more limited and predominately from breast and gastrointestinal malignancies. Samples are collected from consented subjects and de-identified clinical information on the subjects is collected over time. Subjects are consented for research germ line genotyping. Access to the clinical annotation is determined based on need as justified in each investigator''s request or protocol. Anonymized samples from the biorepository are available compliant with UCSD HRPP exempt category 4.
Proper citation: UC San Diego Biorepository (RRID:SCR_004256) Copy
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