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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Platform for multilevel and longitudinal data.Provide researchers such as behavioral and social scientists with tools and education related to study design including Calculating power and sample size for any univariate or multivariate test for general linear multivariate model, assuming fixed predictors;Producing confidence intervals on power estimates for designs with fixed predictors;Producing power calculations for designs with single Gaussian covariate;Supporting designs with unequal group sizes, and complicated covariance structures;Creating basic power curves.
Proper citation: Sample Size Shop (RRID:SCR_021747) Copy
Integrated platform for designing clinical trials.
Proper citation: Trialdesign (RRID:SCR_021749) Copy
https://www.microns-explorer.org/
Portal to release connectivity and functional imaging data collected by consortium of laboratories led by groups at Allen Institute for Brain Science, Princeton University, and Baylor College of Medicine, with support from broad array of teams, coordinated and funded by IARPA MICrONS program. Data include large scale electron microscopy based reconstructions of cortical circuitry from mouse visual cortex, with corresponding functional imaging data from those same neurons.
Proper citation: Microns Explorer (RRID:SCR_021678) Copy
Catalog provides uniformly processed gene expression and splicing QTLs from all available public studies on human. Expression and splicing QTLs recomputed from public datasets.
Proper citation: eQTL Catalogue (RRID:SCR_021700) Copy
Website devoted to papers that contain machine learning datasets, code, methods and evaluation tables. Done together with community, supported by NLP and ML.All content on this website is openly licenced under CC-BY-SA and everyone can contribute.Also operates specialized portals for papers with code in astronomy, physics, computer sciences, mathematics and statistics.
Proper citation: Papers with Code (RRID:SCR_021800) Copy
Platform facilitates comprehensive discovery of and access to multidisciplinary microbiome data in order to unlock new possibilities with microbiome data science. Multi organizational effort to integrate microbiome data across diverse areas in medicine, agriculture, bioenergy, and environment. Founded to support long term advancement of microbiome science.
Proper citation: National Microbiome Data Collaborative (RRID:SCR_022161) Copy
https://evofunvm.dcsr.unil.ch/
Database of metadata and assembly quality metrics for all Arthropod assemblies on NCBI.
Proper citation: Arthropoda Assembly Assessment Catalog (RRID:SCR_021864) Copy
MDAR Framework establishes minimum set of requirements in transparent reporting applicable to studies in life sciences. MDAR checklist is tool for authors, editors and others seeking to adopt MDAR framework for transparent reporting in manuscripts and other outputs and designed to provide harmonizing principle for reporting requirements currently in use at various journals.
Proper citation: MDAR (RRID:SCR_022038) Copy
http://connect-tbi.med.upenn.edu/
Portal for traumatic brain injury data. Common Data Elements (CDEs) and Unique Data Elements (UDEs) for digital neuropathological data and clinical data that will be collected in all CONNECT-TBI center projects. Goal is to establish multi-center, digital neuropathological data and clinical data reporting network with case accrual from each center project. Collected neuropathological data and clinical data available by sharing with center site investigators approved by Administrative Core and by submitting into FITBIR. Central TBI data repository by collecting digital neuropathological data and clinical data from TBI cases and normal controls at each center and posting library of their holdings.
Proper citation: Connect TBI (RRID:SCR_022009) Copy
https://www.hupo.org/human-antibody-initiative/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 19, 2022.The mission of the Human Antibody Initiative (HAI) aims to promote and facilitate the use of antibodies for proteomics research. The initiative consists of two separate activities; (1) the generation of a catalogue of validated antibodies from many different sources and (2) a protein atlas for the expression and localization of human proteins in normal and disease tissue. The two separate activities have as their primary deliverables to generate databases with free public accessibility. The Antibody Resource database (www.antibodypedia.org) is aimed to produce a comprehensive catalogue of validated antibodies towards human proteins. This initiative depends on input from a large number of academic groups and commercial companies. The Protein Atlas initiative (www.proteinatlas.org) is aimed to provide comprehensive and annotated database of high-resolution images showing tissue profiles in normal and cancer tissues. Both databases will be open to the public without restriction (no passwords).
Proper citation: HUPO Antibody Initiative (RRID:SCR_004568) Copy
RIKEN Brain Science Institute (BSI) has a mission to produce innovative research and technology leading to scientific discoveries of the brain. In addition, BSI aims to develop domestic and international brain researchers by creating an environment that will integrate various intellectual disciplines and from that convergence find solutions that will ultimately benefit society in the realms of medicine, engineering, business, and education. In striving toward this goal, BSI has become a leading international center for brain research with a reputation for discovery, innovation, training, and globalization of the scientific enterprise. Brain science is valuable not only for the advancement of science but also because it can greatly impact our society and economy. To meet these expectations, the Brain Science Institute (BSI) was established in 1997 as part of RIKEN, an independent research institution supported by the Japanese government.
Proper citation: RIKEN Brain Science Institute (RRID:SCR_004796) Copy
A network of specialized rehabilitation programs serving Veterans and Service Members with both combat and civilian related Traumatic Brain Injury (TBI) and polytrauma. Services available include: interdisciplinary evaluation and treatment, development of a comprehensive plan of care, case management, patient and family education and training, psychosocial support, and application of advanced rehabilitation treatments and prosthetic technologies.
Proper citation: VA Polytrauma / TBI System of Care (RRID:SCR_004697) Copy
Fonstein, Kogan, Osterman, Overbeek and Vonstein found the non-profit Fellowship for Interpretation of Genomes (FIG) to follow their vision of seeking advances in understanding through comparative analysis of the growing body of genomic data. The team at FIG began a new open source comparative genomics environment, the SEED. The Project to Annotate 1000 Genomes is a central goal of FIG. FIG is a nonprofit organization devoted to providing support for those analyzing genomes. It focuses on organizing the data needed to support interpretation of genomes, providing the infrastructure needed by the world community in its efforts to achieve understanding. FIG offers the key services required to architect and implement a comparative framework for interpreting genomes. In addition, we pick specific, critical problems and attempt to actively participate in the unraveling of the secrets within these amazing entities. It is only by merging the work of building infrastructure with the applications that use it that we will more deeply understand what is needed at each step.
Proper citation: Fellowship for Interpretation of Genomes (RRID:SCR_004821) Copy
https://knightadrc.wustl.edu/center-events/
Videos of Knight ADRC related events for educational and informational purposes. A link to additional Center produced media is provided to access the Knight ADRC YouTube Channel. Videos are in HTML5 mp4 format and are available in 1080p or 4K resolution.
Proper citation: WU Knight ADRC Multimedia Presentations (RRID:SCR_005147) Copy
http://noble.gs.washington.edu/proj/percolator/
Percolator post-processes the results of a shotgun proteomics database search program, re-ranking peptide-spectrum matches so that the top of the list is enriched for correct matches. Shotgun proteomics uses liquid chromatography-tandem mass spectrometry to identify proteins in complex biological samples. We describe an algorithm, called Percolator, for improving the rate of peptide identifications from a collection of tandem mass spectra. Percolator uses semi-supervised machine learning to discriminate between correct and decoy spectrum identifications, correctly assigning peptides to 17% more spectra from a tryptic dataset and up to 77% more spectra from non-tryptic digests, relative to a fully supervised approach. The yeast-01 data is available in tab delimetered format. The SEQUEST parameter file and target database for the yeast and worm data are also available.
Proper citation: Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets (RRID:SCR_005040) Copy
https://www.har.mrc.ac.uk/about/mammalian-genetics-unit
It is now widely known that animals share many genes with humans and can suffer from the same diseases, for example diabetes or deafness. Investigating these diseases in animals can provide vital leads to understanding both their causes and ways to treat them in humans. This approach to medical research lies at the heart of work at the MRC Mammalian Genetics Unit (MGU) at Harwell in Oxfordshire. In 1995 the MRC Radiobiology Unit was reconstituted to form two new units, the Radiation and Genome Stability Unit and the MGU. These opened in January 1996, together with the UK Mouse Genome Centre which is now part of MGU, making MRC Harwell a unique campus for multi-disciplinary genetics research. Since MGU's Director Steve Brown took the reins in 1996, the unit has dramatically expanded its scientific scope and increased its personnel from 40 to over 100. It now has 13 research programs encompassing molecular genetics, genomics, genetic manipulation and data analysis at all levels, from single genes to the whole genome. With a combination of cutting-edge facilities and expertise unrivaled in Europe, MGU Harwell has become firmly established as one of the world's leading academic centres for mouse genetics.
Proper citation: MRC Mammalian Genetics Unit (RRID:SCR_005378) Copy
http://hnrc.hivresearch.ucsd.edu/
The mission of the HIV Neurobehavioral Research Center (HNRC) is to increase our understanding of how HIV and other diseases affect the human nervous system. The HNRC conducts local, national, and international research devoted to advancing our knowledge of the prevention, diagnosis and treatment of HIV-related diseases as they affect the brain and nervous system, and result in impairment of everyday functioning. Research areas of the Center include: - The incidence, prevalence, and features of neurocognitive impairment caused by HIV - The attributes of the virus, host, and host-virus interactions that determine the presentation of HIV-associated neurocognitive disorders - Possible molecular and cellular mechanisms of nervous system impairment, including the mechanisms by which host-virus factors generate neural injury and neurobehavioral disorders - The cerebrospinal fluid (CSF) as a window on CNS events * The role of co-pathogens and comorbidities in neuroAIDS (e.g., hepatitis C infection, methamphetamine abuse) - Real life implications of neurocognitive impairment in terms of work, daily life, and survival - The effects of HIV disease and neurocognitive impairment on family and social adaptation - NeuroAIDS in resource limited settings - Treatments for neurocognitive impairment and behavioral interventions HNRC also has a Developmental Grants Program (DGP), the primary goal of which is the initiation of innovative studies by junior faculty and trainees at UCSD or affiliated institutions with the following objectives: 1. Recruitment to neuroAIDS research of new investigators or established investigators without prior experience in the field; 2. Generation and pilot testing of new research initiatives; 3. Fostering collaboration among investigators from throughout Southern California. The program provides to qualified investigators and trainees any appropriate combination of the following forms of support: 1. Small, 1-2 year grants to support pilot studies; 2. Access to HNRC core resources such as data, specimens, participants, equipment, administrative support, or expert consultation and technical assistance. Lastly, The the NHRC Mentored Investigator Program recruits, supports, and follows the progress of graduate students, postdoctoral (Ph.D. or M.D.) fellows, and junior faculty in disciplines relevant to HNRC research. The HNRC is committed to tailoring our training opportunities to the backgrounds and interests of candidates from a variety of disciplines who join us with various levels of training and experience in research. We have and will continue to provide training and mentoring of medical students, doctoral students in clinical psychology, and postdoctoral fellows in Medicine, Psychiatry, Neurology, and Psychology. Sponsors: The Center is supported by public funding from the National Institutes of Health, the State of California, and other sources.
Proper citation: HIV Neurobehavioral Research Center (RRID:SCR_005370) Copy
The research of the group concentrates on the molecular biology of Gram-positive bacteria, with Bacillus subtilis and Lactococcus lactis as the main model organisms. A number of important (human) pathogens are also investigated: Bacillus cereus, Streptococcus pneumoniae and Enterococcus faecalis. The nature of the research is both fundamental and application-oriented. Transcript- and protein profiling by high-throughput technologies such as DNA microarrays and proteomics tools are being used. The very large data sets generated are analyzed by employing existing and novel bioinformatics tools. Major lines of research are in the field of functional genomics of these organisms, using systems- and synthetic biology approaches.
Proper citation: MolGen (RRID:SCR_005700) Copy
http://www.solvetherapies.co.uk
Our hope and aims are to empower those affected by common life difficulties such as Anxiety, Depression, low Self-Esteem etc to overcome their obstacles and achieve their full and true potential. Our core approach is client-centred and we aim to convey to each client the ''core conditions'' of empathy, congruence and unconditional positive regard. Using Compassion focused Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT) among other approaches we gear all therapy treatments towards clients unique needs and goals. Passionate about research in all therapeutic and associated fields, we want to continue to keep our fingers on the pulse of developments in this area of work. We at Solve Therapies strive to empower all of our clients to choose helpful, rational thoughts and actions and to do so with less shame and self-criticism through the use of Cognitive Behavioural Therapy and Compassion-focused techniques. We offer a confidential, professional therapeutic service using Cognitive Behavioural Therapy and other forms of counseling/psychotherapy. All therapists are accredited and regulated by the British Association of Counselling & Psychotherapy (BACP) and/or British Association of Behavioural and Cognitive Psychotherapy (BABCP), the professional bodies who regulate, inform and ensure ethical practice. We also provide useful information on common difficulties and on how you can learn how to become your own therapist and manage your difficulties in the long term, with counselling venues throughout Northern Ireland including Belfast, Portrush, Antrim and Portglenone in order to provide flexibility for client appointments. ''''''S''''''olution-focused ''''''O''''''ptions ''''''L''''''ife-change ''''''V''''''alidation ''''''E''''''mpathy
Proper citation: Solve Therapies (RRID:SCR_005590) Copy
Data resource catalog that collates metadata on bioinformatics Web-based data resources including databases, ontologies, taxonomies and catalogues. An entry includes information such as resource identifier(s), name, description and URL. ''''Query'''' lines are defined for each resource that describe what type(s) of data are available, in what format, how (by what identifier) the data can be retrieved and from where (URL). DRCAT was developed to provide more extensive data integration for EMBOSS, but it has many applications beyond EMBOSS. DRCAT entries (including ''''Query'''' lines) are annotated with terms from the EDAM ontology of common bioinformatics concepts.
Proper citation: DRCAT Resource Catalogue (RRID:SCR_005931) Copy
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