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The 16 affiliated Model System centers throughout the United States are responsible for gathering and submitting the core data set to the national database as well as conducting research studies on traumatic brain injury (TBI) both in collaboration with the other centers and within our own site. Through our research we hope to learn more about TBI and about the issues and concerns of people with TBI. Our goals are to improve the outcome and quality of life for people who have had brain injuries and for those who are caring for the person with a TBI. The North Texas Traumatic Brain Injury Model System (NT-TBIMS) pools the efforts and talents of individuals from the Departments of Neurosurgery, Neurology, Physical Medicine and Rehabilitation, Psychiatry (Neuropsychiatry), and Neuroradiology of the two leading medical institutions in the North Texas region. To be a patient involved in the research being conducted by the North Texas Traumatic Brain Injury Model System you must have suffered a TBI, be at least 16 years of age, have received initial treatment for the TBI at either Parkland Health and Hospital System or Baylor University Medical Center and then have received rehabilitative care at either Parkland, University Hospital Zale-Lipshy, or Baylor Institute for Rehabilitation. The patient must also be able to understand and sign an informed consent to participate or, if unable, have a family member or a legal guardian who understands the form sign the informed consent for the patient.
Proper citation: North Texas Traumatic Brain Injury Model System (RRID:SCR_005879) Copy
UTRdb/UTRsite is a portal to other databases, including Nucleotide Sequence Databases, Protein Sequence Databases, other Sequence databanks, Untranslated Nucleotide Sequence Databases, Mitochondrial Databases, Mutation Databases, and others. The site also allows users to start long-term permanent projects or just to do quick searches, depending on the user''s needs.
Proper citation: UTRdb/UTRsite (RRID:SCR_005868) Copy
http://www.alzheimers.org/clinicaltrials/
A database of Alzheimer's disease and dementia clinical trials currently in progress at centers throughout the U.S.
Proper citation: AD Clinical Trials Database (RRID:SCR_005863) Copy
SIMILE, a joint project conducted by the MIT Libraries and MIT CSAIL, was focused on developing robust, open source tools that empower users to access, manage, visualize and reuse digital assets. SIMILE seeks to enhance interoperability among digital assets, schemata/vocabularies/ontologies, metadata, and services. A key challenge is that the collections which must inter-operate are often distributed across individual, community, and institutional stores. We seek to be able to provide end-user services by drawing upon the assets, schemata/vocabularies/ontologies, and metadata held in such stores. SIMILE will leverage and extend DSpace, enhancing its support for arbitrary schemata and metadata, primarily though the application of RDF and semantic web techniques. The project also aims to implement a digital asset dissemination architecture based upon web standards. The dissemination architecture will provide a mechanism to add useful views to a particular digital artifact (i.e. asset, schema, or metadata instance), and bind those views to consuming services. To guide the SIMILE effort we will focus on well-defined, real-world use cases in the libraries domain. Since parallel work is underway to deploy DSpace at a number of leading research libraries, we hope that such an approach will lead to a powerful deployment channel through which the utility and readiness of semantic web tools and techniques can be compellingly demonstrated in a visible and global community. The SIMILE Project and its members are fully committed to the open source principles of software distribution and open development and for this reason, it releases the created intellectual property (both software and reports) under a BSD-style license. The SIMILE Project Team Members gladly welcome community efforts.
Proper citation: SIMILE (RRID:SCR_005862) Copy
http://idp1.force.cs.is.nagoya-u.ac.jp/pscdb/
Database for protein structural change upon ligand binding that are classified into 7 classes in terms of the ligand binding sites and the location where the dominant motion occurs. # Coupled Domain motions are the domain motions induced upon ligand binding. # Independent Domain motions are the observable domain motions regardless of ligand binding. # Coupled Local motions are the local motions induced upon ligand binding. # Independent Local motions are the observable local motions regardless of ligand binding. # Burying ligand motions are imaginable motions required to hold ligand protein-inside. # No significant motions mean just nothing happen. # Other motions are motions unclassified into domain and local motions. Proteins are flexible molecules that undergo structural changes to function. The Protein Data Bank contains multiple entries for identical proteins determined under different conditions, e.g. with and without a ligand molecule, which provides important information for understanding the structural changes related to protein functions. We gathered 839 protein structural pairs of ligand-free and ligand-bound states from monomeric or homo-dimeric proteins, and constructed the Protein Structural Change DataBase (PSCDB). In the database, we focused on whether the motions were coupled with ligand binding. As a result, the protein structural changes were classified into seven classes, i.e. coupled domain motion (59 structural changes), independent domain motion (70), coupled local motion (125), independent local motion (135), burying ligand motion (104), no significant motion (311) and other type motion (35). PSCDB provides lists of each class. On each entry page, users can view detailed information about the motion, accompanied by a morphing animation of the structural changes.
Proper citation: PSCDB - Protein Structural Change DataBase (RRID:SCR_006116) Copy
One of only four NCRR-supported centers with the capability to conduct biomedical research in the chimpanzee, it offers chimpanzee-derived cell lines, antibodies and other biological materials, along with a registry of biologic reagents that are known to work in the chimpanzee. The Resource and Management Core is responsible for providing animal resources, tissues/biological fluids, cell lines, expert advice and research support to NIH extramural and intramural programs, other federal agencies and private sponsors. The Resource-Related Research Core conducts research to improve the health of the animals maintained, with special emphasis on studies that will enhance the usefulness of the chimpanzee as a model for studies of human disease. Resource-related research will focus on characterization of the immune system of the chimpanzee, expansion of our understanding of chimpanzee cardiomyopathy as a potential human disease model and comparisons of the physiologic and immunological consequences of research manipulations on chimpanzees trained to voluntarily cooperate with research procedures. By expanding the resources available, conducting resource-related research and containing costs, the CBRR will continue to provide a critically important, highly specialized research resource to address important human health issues.
Proper citation: Chimpanzee Biomedical Research Resource (RRID:SCR_006289) Copy
Medical school and medical research center connected to Indiana University. Its principal research and medical center is on Indiana University – Purdue University Indianapolis campus in Indianapolis.
Proper citation: Indiana University School of Medicine; Indiana; USA (RRID:SCR_012916) Copy
http://www.ed.ac.uk/schools-departments/vet/
At the vanguard of veterinary education since William Dick founded the School in 1823, the Royal (Dick) School of Veterinary Studies is one of the world''s most innovative and influential centers for clinical care and student education. Using outstanding clinical facilities, we provide veterinary services of the highest standards and a stimulating educational experience for our students, within an environment rich in high quality interdisciplinary research. Affectionately known as the ''Dick Vet'', the School is part of the College of Medicine and Veterinary Medicine at the University of Edinburgh, one of the top 15 centers of biomedical research in the world with annual research awards in excess of 100 million pounds. Our research spans all aspects of veterinary medicine, from molecules and genes through to animal and human populations. Our partnership with the Medical School is summed up in the ethos - One Health. Our vision is simple yet ambitious: we want to take the School''s work to a new level as a world leader in veterinary research and training. By 2011 we will have invested over 100 million pounds in building state-of-the-art teaching facilities, clinics and laboratories. We attract, and actively recruit, the world''s leading veterinary teachers, clinicians and researchers to maintain our customary high ranking in the UK league tables for international excellence in our teaching and research.
Proper citation: University of Edinburgh Royal (Dick) School of Veterinary Studies; Scotland; United Kingdom (RRID:SCR_012845) Copy
Proper citation: Texas Southern University; Texas; USA (RRID:SCR_012737) Copy
A national research infrastructure that provides bioinformatics support to life science researchers in Sweden. Their work is supported by the Swedish Research Council.
Proper citation: Bioinformatics Infrastructure for Life Sciences (RRID:SCR_014723) Copy
Proper citation: Macquarie University; Sydney; Australia (RRID:SCR_012796) Copy
http://www.mcgill.ca/medicine/
Proper citation: McGill University Faculty of Medicine; Montreal; Canada (RRID:SCR_012888) Copy
http://www.med.uc.edu/Home.aspx
Proper citation: University of Cincinnati College of Medicine; Ohio; USA (RRID:SCR_012889) Copy
http://www.uni-hamburg.de/index_e.html
Public research and education university in Northern Germany with main campus located in central district of Rotherbaum, with affiliated institutes and research centres spread around city state.
Proper citation: University of Hamburg; Hamburg; Germany (RRID:SCR_012922) Copy
Proper citation: Eindhoven University of Technology; North Brabant; Netherlands (RRID:SCR_003354) Copy
Proper citation: University of Manitoba; Manitoba; Canada (RRID:SCR_003867) Copy
Public research university in Beersheba, Israel. Ben-Gurion University of the Negev has five campuses: the Marcus Family Campus, Beer Sheva; the David Bergmann Campus, Beer Sheva; the David Tuviyahu Campus, Beer Sheva; the Sede Boqer Campus, and Eilat Campus.
Proper citation: Ben-Gurion University of the Negev; Beer-Sheva; Israel (RRID:SCR_004031) Copy
Proper citation: National Yang-Ming University; Taipei; Taiwan (RRID:SCR_004826) Copy
Proper citation: Kumamoto University; Kumamoto; Japan (RRID:SCR_004102) Copy
http://www.usherbrooke.ca/accueil/english/
Proper citation: University of Sherbrooke; Quebec; Canada (RRID:SCR_003887) Copy
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