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http://www.scienceexchange.com/facilities/meg-mcgill

MEG (Magnetoencephalography) is a neuroimaging technology for cognitive and clinical brain research. In a nutshell, MEG measures non-invasively the tiny magnetic fields generated by neuronal currents. A unique asset of MEG imaging is its unrivaled temporal resolution, reaching the millisecond time scale across the entire brain volume. On the clinical side, MEG has been typically indicated for the pre-surgical work-up of severe, drug-resistant epilepsy and the functional pre-surgical mapping of brain tumors. There is however great potential to use MEG as an instrument of choice to investigate other neurological syndromes and neuropsychiatric disorders (e.g., stroke, dementia, movement disorders, depression, etc.). Overall, MEG has strong value in revealing the dynamics of brain activity involved in subject''''s perception, cognition and responses: it has provided unique insight on the time-resolved processes ruling brain functions (resting-state dynamics, language, motor control, visual and auditory perception, etc.) and dysfunctions (movement disorders, tinnitus, chronic pain, dementia, etc.). MEG(at)McGill provides a full-suite of services related to MEG and MEG/EEG studies. This includes a variety of training programs for use of the MEG and related data acquisition and analysis software, Brainstorm.

Proper citation: MEG(at)McGill (RRID:SCR_012277) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/electron-microscopy-core-facility-bgsu

The Microscopy Core Facility at BGSU offers a range of services, including Scanning electron microscopy (SEM) and Transmission electron microscopy (TEM).

Proper citation: BGSU Electron Microscopy Core Facility (RRID:SCR_012271) Copy   

•   Source: SciCrunch Registry

https://www.mq.edu.au/research/research-centres-groups-and-facilities/innovative-technologies/centres/mqcqe

Macquarie University has established a new multidisciplinary research centre combining physics, mathematics, computer science, engineering and biochemistry to engage in novel research towards deeping our understanding in quantum science and technology.

Proper citation: Macquarie University MQ Research Centre in Quantum Science and Technology (RRID:SCR_012159) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/vcu-nanomaterials-characterization-center-vcu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Nanomaterials Characterization Center at Virginia Commonwealth University is a state of the art 4000 sq. ft. facility located within the new Health and Life Science Engineering Facility. The Center provides an academic structure for students in natural sciences, mathematics, engineering, and medicine to participate in nanoscience and nanotechnology research to acquire the skills necessary to pursue such careers. In the past year, VCU received two National Science Foundation major research instrumentation grants totaling more than $1.6 million to expand its capabilities for research in materials science. Combining these federal awards with state instrumentation grants and private donations, the facility has been able to build a state of the art facility with over $5 million in new equipment. This new equipment will allow faculty and student researchers from both VCU campuses, as well as other universities.

Proper citation: VCU Nanomaterials Characterization Center (RRID:SCR_012162) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/animal-models-core

The UNC Animal Models Core Facility provides the full range of mouse genetic modification services, reagents and related technologies. The Core''s services are available to both UNC and Non-UNC clients. Transgenic (pronuclear injection) animals can be generated in C57BL/6, FVB or C57BL/6 X DBA2 hybrid strains. Services for creating transgenic mice include transgene design, construct generation, isolation of the transgene fragment, pronuclear microinjection, founder genotyping and breeding. The core also offers the full suite of services for BAC (bacterial artificial chromosome) recombineering and microinjection of BAC transgenes. Gene targeting services are available in ES cells from C57BL/6 or 129P2/Ola strains. Other strains available upon request. Gene targeting services include design and cloning of targeting vectors, creating gene-targeted ES cells, blastocyst microinjection of the ES cells to create transmitting chimeras and chimera breeding for germline transmission. The core can also provide Southern blot validation and blastocyst microinjection of ES cells from EUCOMM, KOMP or other consortia. Additional services include Cre- or Flp-mediated excision in ES cells or in vivo, chromosome counting, PCR screening and Southern blotting. Rat model production is also available.

Proper citation: UNC School of Medicine Animal Models Core (RRID:SCR_012167) Copy   

•   Source: SciCrunch Registry

https://www.moffitt.org/research-science/shared-resources/proteomics-and-metabolomics/

Provides instrumentation for proteomics and metabolomics studies, including protein, peptide and metabolite separations, MS instrumentation for protein, peptide and metabolite analysis, and data systems, software, and bioinformatics tools for data archiving and analysis. Proteomics Core performs routine analytical proteomics services, including target discovery, identification and quantitation, and also provides platforms for functional proteomics using variety of strategies for protein separation, sub-proteome enrichment, post-translational modification analysis, and quantitation.

Proper citation: Moffitt Cancer Center Proteomics and Metabolomics Core Facility (RRID:SCR_012168) Copy   

•   Source: SciCrunch Registry

https://www.uclahealth.org/departments/pathology/research-services/translational-pathology-core-laboratory-tpcl

Facility in the UCLA Department of Pathology and Laboratory Medicine and UCLA Jonsson Comprehensive Cancer Center Shared Facility. Provids pathology related services in support of basic, translational and clinical research at UCLA. Provides consultative services to investigators in pathology-related study design, tissue selection, microscopic interpretation, immunohistochemistry, laser capture microdissection, digital image analysis, and IRB-related tissue questions.

Proper citation: University of California at Los Angeles Translational Pathology Core Facility (RRID:SCR_012201) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/ccib-dna-core-mgh-harvard

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 2025.Welcome to the CCIB DNA Core at Massachusetts General Hospital! The mission of the DNA Core is to accelerate fundamental scientific discoveries that will improve human health. Our professional team is committed to help investigators solve highly diverse biological and biomedical research questions by providing a portfolio of state-of-the-art molecular biology services, specialized expertise, detailed advice and support. We are constantly striving to advance research productivity by reliably generating the highest quality data with rapid turn-around time and competitive pricing, and by working with our clients on an individual basis to address and satisfy their specific research needs. Realizing the constant changes of our customers_������������_ demands, we make every effort to continuously improve our services and to offer new and innovative solutions. The DNA Core, founded in 1996, is a non-profit research core laboratory within the Center for Computational and Integrative Biology of Massachusetts General Hospital Boston providing high-quality genomics technology services and expertise for academic research institutions and for business (for-profit) organizations. The majority of the core''''s clients are investigators from Massachusetts General Hospital and the greater Partners research community. The core also serves researchers from external academic institutions and biotech companies in Massachusetts as well as other states in the United States. Our facility provides high-quality molecular biology services in three major areas: Our DNA Sequencing group functions both as a small-scale sequencing facility and a center for large-scale sequencing projects. It is offering various genomics technologies, including ABI Sanger DNA sequencing, Microsatellite analysis, plasmid validation and primer walking. Currently, we are exploring new opportunities and are planning to expand our service portfolio soon. Our DNA Synthesis lab serves the research community with custom oligonucleotides (standard, degenerate, and modified). To diversify our current service options, we are in the process of exploring potential partnerships with third party vendors. Our Research Laboratory Automation group has been designed as a flexible entity within the DNA Core to extend the benefits of laboratory automation to a diverse user group and to assist in the execution of a variety of molecular biology projects that require large-scale robotics support. The group offers standard and custom high-throughput sample processing services, including protocol development, for various molecular biology and genomics applications. Current services include Mouse genotyping, cDNA and siRNA library screening, bacterial colony picking, library replication and archiving, 96-well plasmid DNA purification, large-scale PCR purification, and custom qPCR assays. In addition to providing the currently existing services for the research community, all three groups of the DNA Core are continuously engaged in the evaluation and/or development of new service options and in the optimization of current and new technologies and services.

Proper citation: MGH CCIB DNA Core (RRID:SCR_012281) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/chemical-probe-synthesis-facility

Located in the new Northwest Corner building on the Morningside campus of Columbia University in New York City, the Columbia University Chemical Probe Synthesis Facility (CPS facility) is a shared resource that assists researchers in designing and synthesizing small molecule probes for stem cell research projects. The CPS facility offers expertise, advice and services in the following areas: 1. Virtual screening and computational design of small molecules 2. Organic synthesis of individual compounds, building blocks or libraries of compounds 3. Drug metabolism/pharmacokinetics (DMPK) and metabolic profiling of small molecules

Proper citation: Columbia Chemical Probe Synthesis Facility (RRID:SCR_012247) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/protein-chemistry-technology-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein Chemistry Technology Core was established to provide efficient, high quality services to researchers in the academic community. The services presently offered include peptide synthesis and Edman protein sequencing. Our facility, its state-of-the-art instrumentation, and computer software is constantly upgraded to ensure the highest possible level of support. It is our aim to provide quality performance and offer experienced support, both through our products and people.

Proper citation: UT Southwestern Protein Chemistry Technology Core (RRID:SCR_012254) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/protein-production-and-cell-biology-laboratory-cddi

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein production can be a significant bottleneck during early phase drug discovery. Our production facilities are fully equipped and staffed to help researchers produce proteins in bacteria, yeast or insect cells. Whether the protein is hopelessly insoluble or difficult to produce in quantity, the core staff is ready to work with individuals to turn failure into success. The Cell Biology facility provides researchers access to cell sorting and analysis for target characterization and validation. The BD FACS Aria II sorter is BSL2 capable permitting levels of safety in cell sorting not available in most flow cores. A second BD Canto II flow cytometer provides automated sampling for analytical flow cytometry. Fully automated Zeiss Axiovert 100 deconvolution and Lecia DM 6000 (laser microcapture) microscopes provide tools for cell imaging and content analyses.

Proper citation: USF Protein Production and Cell Biology Laboratory (RRID:SCR_012263) Copy   

•   Source: SciCrunch Registry

http://sydneynano.com/

The MAU is comprised of five separate characterisation nodes: (1) Electron microscopy and microanalysis (2) Scanning probe microscopy (3) X-ray characterisation (4) Electrical measurement and characterisation (5)Optical characterisation. As well as a materials fabrication and processing equipment suite. This research infrastructure is supported by an academic Director, a Research Laboratory Manager and three highly experienced and highly skilled Professional Officers.

Proper citation: UTS Microstructural Analysis Unit (RRID:SCR_012268) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/chemical-technologies-research-facility-uts

The research facility in Chemical Technologies pulls together the resources of several well equipped laboratories specialising in chemistry and materials science. The facility is particularly focused on chemical, forensic, material and biochemical analysis, and materials technology, and is set up to serve the needs of Australian industry and academia in these areas. Specialties of the facility include the physical and mechanical characterization of engineering materials, and the chemical and physical characterisation of forensic and pharmaceutical samples. The facility is equipped to produce and characterise a diverse range of organic and inorganic materials, and is backed by a team of experienced researchers.

Proper citation: UTS Chemical Technologies Research Facility (RRID:SCR_012267) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-biophysical-sciences-and-engineering-cbse

Since 1986, The Center for Biophysical Sciences and Engineering (CBSE) has integrated our strengths to become a leading structural biology center capable of embracing the _������������_genes to drug_���� paradigm. We are one of the world''''s largest Structure Based Drug Discovery facilities with over 110 employees, including 15 Ph.D. level crystallographers. The CBSE is centered on a suite of integrated high throughput laboratories allowing us to offer a cost-effective platform of discovery services designed to increase the efficiency and success for drug discovery projects with industry, academic and government partners.

Proper citation: UAB Center for Biophysical Sciences and Engineering (RRID:SCR_012509) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/flow-cytometry-core-facility-uchicago

Flow Cytometry Facility at the University of Chicago is committed to providing the highest quality services to all its investigators.

Proper citation: UChicago Flow Cytometry Core Facility (RRID:SCR_012508) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/nanofabrication-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16, 20224. Nanofabrication Facility houses three instruments for patterning of flat surfaces and selective etching of materials. Researchers fabricate devices and structures to demonstrate novel device concepts and to characterize new materials. To carry out these functions this new facility consists of three instruments: a Tescan Electron-Beam Lithography Tool, an OAI high resolution Mask Aligner and Advanced Vacuum/Plasma Therm Reactive Ion Etcher.

Proper citation: UConn Nanofabrication Facility (RRID:SCR_012346) Copy   

•   Source: SciCrunch Registry

https://www.umassmed.edu/MSF/Proteomics/

The University of Massachusetts Medical School Proteomics and Mass Spectrometry Facility is an analytical laboratory resource offering state-of-the-art proteomic, lipid, and small molecule mass spectrometric analyses to both the academic and external scientific community. This includes resources for study design, sample preparation and cleanup, sample fractionation, instrumentation, informatics, data interpretation, and publication assistance.

Proper citation: UMMS Proteomics and Mass Spectrometry Facility (RRID:SCR_012500) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/dna-microarray-core-facility-ualbany

Core provides microarray services for Affymetrix GeneChip arrays, Agilent microarrays, NimbleGen microarrays and custom-produced spotted cDNA microarrays. Projects developed through DNA Microarray Center have made use of arrays from variety of genomes, eukaryotic, prokaryotic, and plant. Core services includes RNA/DNA isolation, gene expression, miRNA, Chip-chip, Rip-chip and DNA methylation services. Provides bioinformatics tools for further analysis of results of expression experiments.

Proper citation: University at Albany Center for Functional Genomics DNA Microarray Core Facility (RRID:SCR_012502) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cellular-and-molecular-biology-core-uvm

This is a free facility for everyone at the University of Vermont; however, preference will be given to the principle investigators listed on the COBRE grant, followed by members of the neuroscience community and finally, the university as a whole. Check in advance when planning experiments to determine space and equipment availability.

Proper citation: UVM Cellular and Molecular Biology Core (RRID:SCR_012505) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/metabolite-profiling-facility-purdue

The Metabolite Profiling Facility (MPF) provides state-of-the-art technologies that enable both qualitative (defining all components of a metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems. This facility employs highly sensitive mass spectrometry coupled with liquid chromatography and multi-dimensional gas chromatography for precise sample analysis. Metabolite profiling is an integral component of systems biology, an exciting field that combines genomics, transcriptomics and proteomics to define cellular functionality. Our elite scientists will empower researchers with new technologies, methods development, expert training and consultation.

Proper citation: Bindley Bioscience Metabolite Profiling Facility (RRID:SCR_012352) Copy   

•   Source: SciCrunch Registry