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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
bsseq
 
Resource Report
Resource Website
1+ mentions
bsseq (RRID:SCR_001072) data processing software, data analysis software, software resource, sequence analysis software, software application R package with tools for analyzing and visualizing bisulfite sequencing data. bisulfite sequencing, analyze, r, sequence analysis software, data analysis software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_01847, biotools:bsseq https://bio.tools/bsseq SCR_001072 bsseq - Analyze manage and store bisulfite sequencing data 2026-08-04 09:40:18 8
SplitSeek
 
Resource Report
Resource Website
1+ mentions
SplitSeek (RRID:SCR_001012) data processing software, data analysis software, software resource, sequence analysis software, software application THIS RESOURCE IS NO LONGER IN SERVICE, documented September 20, 2016. A program for de novo prediction of splice junctions in RNA-seq data. bioinformatics alignment, sequence analysis software, de novo, prediction, rna seq, rna, splice junction, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:20236510 THIS RESOURCE IS NO LONGER IN SERVICE biotools:splitseek, OMICS_01253 https://bio.tools/splitseek http://www.uppmax.uu.se/software/splitseek SCR_001012 2026-08-04 09:40:16 1
AutoAssemblyD
 
Resource Report
Resource Website
AutoAssemblyD (RRID:SCR_001087) data processing software, data analysis software, software resource, sequence analysis software, software application Software which performs local and remote genome assembly by several assemblers based on an XML Template which can replace the large command lines required by most assemblers. genome, genome assembly, xml, sequence analysis software, local genome assembly, remote genome assembly, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24143057 Free, Available for download, Freely available biotools:autoassemblyd, OMICS_00874 https://bio.tools/autoassemblyd SCR_001087 2026-08-04 09:40:18 0
Enrichr
 
Resource Report
Resource Website
1000+ mentions
Enrichr (RRID:SCR_001575) Enrichr data analysis service, analysis service resource, software resource, software application, production service resource, service resource A web-based gene list enrichment analysis tool that provides various types of visualization summaries of collective functions of gene lists. It includes new gene-set libraries, an alternative approach to rank enriched terms, and various interactive visualization approaches to display enrichment results using the JavaScript library, Data Driven Documents (D3). The software can also be embedded into any tool that performs gene list analysis. System-wide profiling of genes and proteins in mammalian cells produce lists of differentially expressed genes / proteins that need to be further analyzed for their collective functions in order to extract new knowledge. Once unbiased lists of genes or proteins are generated from such experiments, these lists are used as input for computing enrichment with existing lists created from prior knowledge organized into gene-set libraries. bed, gene, software as a service, rna-seq, analyze, protein, function, gene list, visualization, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
PMID:23586463 Free, Freely available biotools:enrichr, SciRes_000171 https://bio.tools/enrichr SCR_001575 2026-08-04 09:40:25 4351
UNAFold
 
Resource Report
Resource Website
100+ mentions
UNAFold (RRID:SCR_001360) data processing software, software application, software resource, data analysis software Software package for nucleic acid folding and hybridization prediction. It has capabilities to predict folding for single-stranded RNA or DNA through a combination of free energy minimization, partition function calculations and stochastic sampling. The program runs on Unix and Linux platforms as well as Mac OS X and Windows. software, nucleic acid, folding, hybridization, prediction, rna, dna, stochastic sampling, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University at Albany; New York; USA
Free, Available for download, Freely available biotools:unafold, nif-0000-07753 http://mfold.rna.albany.edu/ SCR_001360 The UNAFold Web Server, UNAFold Web Server 2026-08-04 09:40:21 304
PAZAR
 
Resource Report
Resource Website
10+ mentions
PAZAR (RRID:SCR_005410) PAZAR storage service resource, software resource, data repository, service resource, database, data or information resource Database that unites independently created and maintained data collections of transcription factor and regulatory sequence annotation. The flexible PAZAR schema permits the representation of diverse information derived from experiments ranging from biochemical protein-DNA binding to cellular reporter gene assays. Data collections can be made available to the public, or restricted to specific system users. The data ''boutiques'' within the shopping-mall-inspired system facilitate the analysis of genomics data and the creation of predictive models of gene regulation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. transcription factor, target gene, regulatory sequence, transcription factor profile, annotation, sequence, profile, transcription factor binding profile, chip, chip-seq, gene, cis-regulatory element, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of British Columbia; British Columbia; Canada
has parent organization: SourceForge
PMID:18971253 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00540, biotools:pazar https://bio.tools/pazar SCR_005410 2026-08-04 09:41:21 32
TIGRFAMS
 
Resource Report
Resource Website
100+ mentions
TIGRFAMS (RRID:SCR_005493) JCVI TIGRFAMS, TIGRFAM data set, database, data or information resource Consists curated multiple sequence alignments, Hidden Markov Models (HMMs) for protein sequence classification, and associated information designed to support automated annotation of (mostly prokaryotic) proteins. Starting with release 10.0, TIGRFAMs models use HMMER3, which provides excellent search speed as well as exquisite search sensitivity. See the "TIGRFAMs Complete Listing" page to review the accession, protein name, model type, and EC number (if assigned) of all models. TIGRFAMs is a member database in InterPro. The HMM libraries and supporting files are available to download and use for free from our FTP site. sequence alignment, hidden markov model, protein sequence, classification, protein, protein family, sequence homology, sequence, homology, function, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: InterPro
is related to: InterPro
has parent organization: J. Craig Venter Institute
PMID:23197656 Free nif-0000-03560, OMICS_01700, biotools:tigrfams https://bio.tools/tigrfams http://www.tigr.org/TIGRFAMs SCR_005493 TIGRFAMs 2026-08-04 09:41:22 135
becas
 
Resource Report
Resource Website
10+ mentions
becas (RRID:SCR_005337) data access protocol, software resource, service resource, web service Web application, API and widget able to recognize and annotate biomedical concepts in text.Provides annotations for isolated, nested and intersected entities.Identifies concepts from multiple semantic groups, providing preferred names and enriching them with references to public knowledge resources. Annotation, biomedical concept recognition, annotate biomedical concepts, text, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Aveiro; Aveiro; Portugal
Free, Freely available biotools:becas, OMICS_01173 https://bioinformatics.ua.pt/software/becas/, https://bio.tools/becas SCR_005337 2026-08-04 09:41:21 12
NCBO Annotator
 
Resource Report
Resource Website
1+ mentions
NCBO Annotator (RRID:SCR_005329) NCBO Annotator web service, software resource, data access protocol, production service resource, service resource A Web service that annotates textual metadata (e.g. journal abstract) with relevant ontology concepts. NCBO uses this Web service to annotate resources in the NCBO Resource Index. They also provide this Web service as a stand-alone service for users. This Web service can be accessed through BioPortal or used directly in your software. Currently, the annotation workflow is based on syntactic concept recognition (using concept names and synonyms) and on a set of semantic expansion algorithms that leverage the semantics in ontologies (e.g., is_a relations). Their service methodology leverages ontologies to create annotations of raw text and returns them using semantic web standards. ontology, annotation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: STOP
has parent organization: BioPortal
has parent organization: National Centers for Biomedical Computing
has parent organization: Stanford University; Stanford; California
NHGRI U54 HG004028 PMID:19483092 biotools:bioportal, nlx_144389, OMICS_01172 https://bio.tools/bioportal SCR_005329 Open Biomedical Annotator, NCBO BioPortal Annotator 2026-08-04 09:41:20 6
CoPub
 
Resource Report
Resource Website
1+ mentions
CoPub (RRID:SCR_005327) CoPub data access protocol, software resource, service resource, web service Text mining tool that detects co-occuring biomedical concepts in abstracts from the MedLine literature database. It allows batch input of multiple human, mouse or rat genes and produces lists of keywords from several biomedical thesauri that are significantly correlated with the set of input genes. These lists link to Medline abstracts in which the co-occurring input genes and correlated keywords are highlighted. Furthermore, CoPub can graphically visualize differentially expressed genes and over-represented keywords in a network, providing detailed insight in the relationships between genes and keywords, and revealing the most influential genes as highly connected hubs. microarray, gene, literature, enrich, annotate, network, database, differential expression, bio.tools uses: MEDLINE
uses: Gene Ontology
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Netherlands Bioinformatics Centre
Netherlands Bioinformatics Centre PMID:18442992 Free, Public, Acknowledgement requested OMICS_01178, biotools:copub https://bio.tools/copub http://services.nbic.nl/cgi-bin/copub/CoPub.pl SCR_005327 2026-08-04 09:41:20 5
Maqview
 
Resource Report
Resource Website
Maqview (RRID:SCR_005632) MaqView data processing software, data visualization software, software application, software resource A graphical read alignment viewer specifically designed for the Maq alignment file and allows you to see the mismatches, base qualities and mapping qualities. It is highly efficient in speed, memory and disk usage. Maqview is based on OpenGL and is known to work on both Mac OS X and Linux. Porting to Windows is in principle easy. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
DOI:10.1101/gr.078212.108 GNU General Public License OMICS_00889, biotools:maqview https://bio.tools/maqview, https://sources.debian.org/src/maqview/ SCR_005632 Mapping and Assembly with Qualities Viewer, M.A.Q Viewer 2026-08-04 09:41:24 0
Bowtie
 
Resource Report
Resource Website
10000+ mentions
Bowtie (RRID:SCR_005476) data processing software, alignment software, data analysis software, software resource, sequence analysis software, software application, image analysis software Software ultrafast memory efficient tool for aligning sequencing reads. Bowtie is short read aligner. sequence, analysis, long, reference, read, alignment, gap, local, pair, end, rna, rnaseq, bio.tools is used by: deFuse
is used by: Short Read Sequence Typing for Bacterial Pathogens
is used by: TopHat
is used by: BS Seeker
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Bowtie 2
has parent organization: Johns Hopkins University; Maryland; USA
is required by: RelocaTE
NHGRI R01 HG006102;
NIGMS R01 GM083873;
Amazon Web Services in Education Research
PMID:19261174
DOI:10.1186/gb-2009-10-3-r25
Free, Available for download, Freely available biotools:bowtie, OMICS_00653 https://github.com/BenLangmead/bowtie, https://bio.tools/bowtie, https://sources.debian.org/src/bowtie/ SCR_005476 2026-08-04 09:41:22 13226
MicrobesOnline
 
Resource Report
Resource Website
100+ mentions
MicrobesOnline (RRID:SCR_005507) MicrobesOnline data analysis service, source code, analysis service resource, software resource, production service resource, service resource, database, data or information resource MicrobesOnline is designed specifically to facilitate comparative studies on prokaryotic genomes. It is an entry point for operon, regulons, cis-regulatory and network predictions based on comparative analysis of genomes. The portal includes over 1000 complete genomes of bacteria, archaea and fungi and thousands of expression microarrays from diverse organisms ranging from model organisms such as Escherichia coli and Saccharomyces cerevisiae to environmental microbes such as Desulfovibrio vulgaris and Shewanella oneidensis. To assist in annotating genes and in reconstructing their evolutionary history, MicrobesOnline includes a comparative genome browser based on phylogenetic trees for every gene family as well as a species tree. To identify co-regulated genes, MicrobesOnline can search for genes based on their expression profile, and provides tools for identifying regulatory motifs and seeing if they are conserved. MicrobesOnline also includes fast phylogenetic profile searches, comparative views of metabolic pathways, operon predictions, a workbench for sequence analysis and integration with RegTransBase and other microbial genome resources. The next update of MicrobesOnline will contain significant new functionality, including comparative analysis of metagenomic sequence data. Programmatic access to the database, along with source code and documentation, is available at http://microbesonline.org/programmers.html. microbe, genome, bacteria, archaea, fungi, prokaryote, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
DOE DE-AC02-05CH11231 PMID:19906701 nlx_144607, biotools:microbesonline https://bio.tools/microbesonline SCR_005507 Microbial Genomics Database, Microbes Online 2026-08-04 09:41:22 156
FunCluster
 
Resource Report
Resource Website
1+ mentions
FunCluster (RRID:SCR_005774) FunCluster data processing software, software application, software resource, data analysis software FunCluster is a genomic data analysis algorithm which performs functional analysis of gene expression data obtained from cDNA microarray experiments. Besides automated functional annotation of gene expression data, FunCluster functional analysis aims to detect co-regulated biological processes through a specially designed clustering procedure involving biological annotations and gene expression data. FunCluster''''s functional analysis relies on Gene Ontology and KEGG annotations and is currently available for three organisms: Homo Sapiens, Mus Musculus and Saccharomyces Cerevisiae. FunCluster is provided as a standalone R package, which can be run on any operating system for which an R environment implementation is available (Windows, Mac OS, various flavors of Linux and Unix). Download it from the FunCluster website, or from the worldwide mirrors of CRAN. FunCluster is provided freely under the GNU General Public License 2.0. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible genomic, gene, functional analysis, gene expression, cdna microarray, cdna, microarray, function, cluster, annotation, biological process, statistical analysis, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: Cordelier Research Center
PMID:17007070
PMID:16506959
PMID:16046292
Free for academic use, GNU General Public License, v2 nlx_149242, biotools:funcluster https://bio.tools/funcluster SCR_005774 FunCluster R Package, FunCluster Algorithm 2026-08-04 09:41:26 2
Bambino
 
Resource Report
Resource Website
1+ mentions
Bambino (RRID:SCR_005649) Bambino data analysis service, analysis service resource, software resource, production service resource, service resource A variant detector and graphical alignment viewer for next-generation sequencing data in the SAM/BAM format, which is capable of pooling data from multiple source files. Bambino may be launched online via Java Web Start or downloaded and run locally. java, next-generation sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: National Cancer Institute
PMID:21278191 Https://cgwb.nci.nih.gov/goldenPath/bamview/documentation/Bambino_Click-thru-agreement-for-executable_final.txt OMICS_00876, biotools:bambino https://bio.tools/bambino SCR_005649 Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format 2026-08-04 09:41:24 5
BS Seeker
 
Resource Report
Resource Website
1+ mentions
BS Seeker (RRID:SCR_005641) data processing software, data analysis software, software resource, sequence analysis software, software application Software which performs accurate and fast mapping of bisulfite-treated short reads. Supplementary information and examples are provided on the site. bisulfite sequencing, sequence analysis software, short read, sequence mapping, bio.tools uses: Bowtie
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Bs-Seeker2
has parent organization: University of California at Los Angeles; California; USA
PMID:20416082 Free, Available for download, Freely available OMICS_00578, biotools:bs_seeker https://bio.tools/bs_seeker SCR_005641 Bisulfite Sequence Seeker 2026-08-04 09:41:24 3
InterProScan
 
Resource Report
Resource Website
5000+ mentions
InterProScan (RRID:SCR_005829) data analysis service, data processing software, data analysis software, analysis service resource, web service, software resource, software application, data access protocol, production service resource, service resource Software package for functional analysis of sequences by classifying them into families and predicting presence of domains and sites. Scans sequences against InterPro's signatures. Characterizes nucleotide or protein function by matching it with models from several different databases. Used in large scale analysis of whole proteomes, genomes and metagenomes. Available as Web based version and standalone Perl version and SOAP Web Service. functional, analysis, sequence, protein, nucleotide, predict, presence, domain, site, proteome, genome, metagenome, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Gene Ontology
is related to: RARTF
is related to: InterPro
is related to: LegumeIP
is related to: UniProtKB
has parent organization: European Bioinformatics Institute
European Union ;
Biotechnology and Biological Sciences Research Council ;
EMBL
PMID:15980438
PMID:17202162
PMID:24451626
Free, Available for download, Freely available OMICS_01479, biotools:interproscan_4, nlx_149337 https://www.ebi.ac.uk/interpro/download.html, https://bio.tools/interproscan_4 SCR_005829 InterProScan Sequence Search, InterProScan 2, InterProScan 3, InterProScan 4, InterProScan 5 2026-08-04 09:41:27 6936
ToppGene Suite
 
Resource Report
Resource Website
1000+ mentions
ToppGene Suite (RRID:SCR_005726) data analysis service, resource, portal, analysis service resource, production service resource, service resource, database, data or information resource ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. ToppGene Suite is a one-stop portal for (i) gene list functional enrichment, (ii) candidate gene prioritization using either functional annotations or network analysis and (iii) identification and prioritization of novel disease candidate genes in the interactome. Functional annotation-based disease candidate gene prioritization uses a fuzzy-based similarity measure to compute the similarity between any two genes based on semantic annotations. The similarity scores from individual features are combined into an overall score using statistical meta-analysis. gene portal, enrichment analysis, functional annotation, gene prioritization, protein interaction, bio.tools, FASEB list is listed by: Gene Ontology Tools
is listed by: NIDDK Information Network (dkNET)
is listed by: GUDMAP Ontology
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: ToppCluster
State of Ohio Computational Medicine Center ODD TECH 04-042;
NIDDK 1U01DK70219;
NIDDK P30DK078392
PMID:19465376 Free for academic use nlx_149183, biotools:toppgene_suite https://bio.tools/toppgene_suite SCR_005726 ToppGene 2026-08-04 09:41:26 1030
GoFish
 
Resource Report
Resource Website
1+ mentions
GoFish (RRID:SCR_005682) GoFish data analysis service, source code, analysis service resource, software resource, production service resource, service resource Software program, available as a Java applet online or to download, allows the user to select a subset of Gene Ontology (GO) attributes, and ranks genes according to the probability of having all those attributes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, ontology or annotation browser, java, windows, mac os x, linux, unix, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
has parent organization: Harvard Medical School; Massachusetts; USA
Aventis Pharmaceuticals ;
Howard Hughes Medical Institute ;
NHGRI
PMID:12691998 THIS RESOURCE IS NO LONGER IN SERVICE biotools:gofish, nlx_149126, OMICS_02272 http://llama.mshri.on.ca/Software.html, https://bio.tools/gofish SCR_005682 2026-08-04 09:41:25 1
ccPDB - Compilation and Creation of datasets from PDB
 
Resource Report
Resource Website
1+ mentions
ccPDB - Compilation and Creation of datasets from PDB (RRID:SCR_005870) ccPDB web service, software resource, data access protocol, database, data or information resource ccPDB (Compilation and Creation of datasets from PDB) is designed to provide service to scientific community working in the field of function or structure annoation of proteins. This database of datasets is based on Protein Data Bank (PDB), where all datasets were derived from PDB. ccPDB have four modules; i) compilation of datasets, ii) creation of datasets, iii) web services and iv) Important links. * Compilation of Datasets: Datasets at ccPDB can be classified in two categories, i) datasets collected from literature and ii) datasets compiled from PDB. We are in process of collecting PDB datasetsfrom literature and maintaining at ccPDB. We are also requesting community to suggest datasets. In addition, we generate datasets from PDB, these datasets were generated using commonly used standard protocols like non-redundant chains, structures solved at high resolution. * Creation of datasets: This module developed for creating customized datasets where user can create a dataset using his/her conditions from PDB. This module will be useful for those users who wish to create a new dataset as per ones requirement. This module have six steps, which are described in help page. * Web Services: We integrated following web services in ccPDB; i) Analyze of PDB ID service allows user to submit their PDB on around 40 servers from single point, ii) BLAST search allows user to perform BLAST search of their protein against PDB, iii) Structural information service is designed for annotating a protein structure from PDB ID, iv) Search in PDB facilitate user in searching structures in PDB, v)Generate patterns service facility to generate different types of patterns required for machine learning techniques and vi) Download useful information allows user to download various types of information for a given set of proteins (PDB IDs). * Important Links: One of major objectives of this web site is to provide links to web servers related to functional annotation of proteins. In first phase we have collected and compiled these links in different categories. In future attempt will be made to collect as many links as possible. secondary structure, nucleic acid interaction, ligand interaction, structure, nucleic acid, interaction, ligand, data set, function, protein, annotate, tight-turn, nucleotide interacting residue, metals interacting residue, dna/rna binding residue, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Institute of Microbial Technology; Chandigarh; India
OSDD ;
DBT ;
Council of Scientific and Industrial Research; New Delhi; India
PMID:22139939 biotools:ccpdb, nlx_149416 https://bio.tools/ccpdb SCR_005870 Compilation and Creation of datasets from PDB, ccPDB - Compilation Creation of datasets from PDB 2026-08-04 09:41:28 2

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