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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Mass spectrometer designed for most difficult analytical challenges. Incorporates inventions in ion transmission and control, extended m/z range, and real-time decision making. System suited for proteomics, structural biology, small-molecule, and biopharmaceutical characterization experiments.
Proper citation: Thermo Fisher: Orbitrap Eclipse Tribrid mass spectrometer (RRID:SCR_023618) Copy
Inverted microscope Axio Observer 3 for transmitted light brightfield LED and differential interference contrast. Used for demanding multimodal imaging.
Proper citation: Zeiss: Axio Observer 3 (RRID:SCR_023693) Copy
https://industry.nikon.com/en-us/products/x-ray-ct/xt-h-225-xt-h-320/
Provides insight into the inside of components and specimens, allowing users to visualize, analyze and measure complex internal geometry as well as surfaces, all non-destructively. Versatile microfocus CT system for high resolution inspection in R&D and failure analysis of components ranging from tiny plastic connectors up to aluminum castings.
Proper citation: Nikon: XT H 225 ST uCT system (RRID:SCR_023687) Copy
Pipet-Lite™ XLS+ manual single-channel pipette, 100-1000 μL, uses LTS™ LiteTouch™ tips. Accurate and precise, ergonomic, autoclavable liquid end, rugged and durable (L-1000XLS+)
Proper citation: Rainin: Pipet-Lite LTS Pipette L-1000XLS+ (RRID:SCR_023894) Copy
Pipet-Lite™ XLS+ manual single-channel pipette, 20-200 μL, uses LTS™ LiteTouch™ tips. Accurate and precise, ergonomic, autoclavable liquid end, rugged and durable (L-200XLS+)
Proper citation: Rainin: Pipet-Lite LTS Pipette L-200XLS+ (RRID:SCR_023892) Copy
https://www.hitachi-keu.com/en-gb/iv/hv-f203gvscl.html
High resolution 1/1.8" 3 CCD Progressive Scan Color Camera with 1600 x 1200 pixel (UXGA) that is installed in the ZEISS Axioscan Z1 slide scanner. Integrated functions include electronic shutter from 1/30s to 1/100000s, Long term Integration up to 4s, AGC, external Trigger, Auto Shading, 6 Colour Masking, Frame-On-Demand Function, White Balance, AGC, Black Level Adjustment and Partial Scan Function.
Proper citation: Hitachi: 16-bit 3-CCD color camera HV-F203GV / HV-F203SCL (RRID:SCR_023888) Copy
https://www.sunchrom.de/en/products/maldi-ms-sample-preparation-2/suncollect-cf-spotter.html
CF-Spotter for MALDI-TOF microbial identification. Enables fast, efficient and reproducible sample preparation for MALDI-TOF microbial identification system and relieves your laboratory staff from tedious and time-consuming pipetting. Due to the non-contact application of the solutions, there is no carryover of the samples and the costs for consumables such as pipette tips are eliminated.
Proper citation: SunChrom: SunCollect CF Spotter (RRID:SCR_023906) Copy
https://www.sunchrom.de/en/products/maldi-ms-sample-preparation-2/sundigest.html
SunDigest incubation device provides fully software controlled and highly reproducible digestion process under standardized conditions. Feature includes Temperatures precisely adjustable between 4 °C and 50 °C; On-Tissue digestion process under optimal humidity; Preservation of spatial resolution; High performance digestion at 50 °C; Full digestion process control.Essential for reproducible results.
Proper citation: SunChrom: SunDigest Incubator (RRID:SCR_023905) Copy
Leica ST5010 Autostainer XL provides reproducible, consistent high quality staining, and increased workload throughput compared to manual staining.
Proper citation: Leica: Autostainer ST5010 XL (RRID:SCR_023957) Copy
https://www.beckman.com/flow-cytometry/clinical-flow-cytometers/navios-ex
Designed specifically for clinical laboratory NAVIOS EX 10-color flow cytometer delivers performance with improved sample traceability and reporting functions. Navios EX has two optional ready-to-use IVD reagent systems, the Navios Tetra System for simultaneous identification and enumeration of T, B and NK lymphocytes and the ClearLLab 10C System – the first FDA cleared and CE marked integrated leukemia and lymphoma immunophenotyping system.
Proper citation: Beckman Coulter: Navios EX flow cytometer (RRID:SCR_023797) Copy
https://mass-spec.stanford.edu/instruments
Agilent 6495C triple quadrupole LC/MS system increases capacity and sensitivity for targeted quantitation applications. Used to investigate more diverse and biologically relevant groups of targeted peptides, small molecules and metabolites in single experiment without compromising sensitivity, quantitative accuracy, or linearity.
Proper citation: Agilent: 6495 Triple Quadrupole LC/MS (RRID:SCR_023937) Copy
https://www.ambulatory-monitoring.com/pvt-192-psychomotor-vigilance-monitor
System includes PVT-192 monitor and REACT software. Used for reaction time testing for long-term, large-scale testing of vigilance, effects of sleep deprivation, and drug effects. Used for PVT test wherever measures of performance or sleepiness effects are needed.
Proper citation: Ambulatory Monitoring: Psychomotor Vigilance Task system (RRID:SCR_024213) Copy
http://edboyden.org/05.09.boyden.html
Laser tool that enables neurons to be optically silenced by pulses of yellow light, the light-activated chloride pump halorhodopsin (Halo), in a paper entitled Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. Temporally precise, noninvasive control of activity in well-defined neuronal populations is a long-sought goal of systems neuroscience. We adapted for this purpose the naturally occurring algal protein Channelrhodopsin-2, a rapidly gated light-sensitive cation channel, by using lentiviral gene delivery in combination with high-speed optical switching to photostimulate mammalian neurons. We demonstrate reliable, millisecond-timescale control of neuronal spiking, as well as control of excitatory and inhibitory synaptic transmission. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. The quest to determine how precise neural activity patterns mediate computation, behavior, and pathology would be greatly aided by a set of tools for reliably activating and inactivating genetically targeted neurons, in a temporally precise and rapidly reversible fashion. Having earlier adapted a light-activated cation channel, 1channelrhodopsin-2 (ChR2), for allowing neurons to be stimulated by blue light, we searched for a complementary tool that would enable optical neuronal inhibition, driven by light of a second color. Here we report that targeting the 1codon-optimized form of the light-driven chloride pump halorhodopsin from the archaebacterium Natronomas pharaonis (hereafter abbreviated Halo) to genetically-specified neurons enables them to be silenced reliably, and reversibly, by millisecond-timescale pulses of yellow light. We show that trains of yellow and blue light pulses can drive high-fidelity sequences of hyperpolarizations and depolarizations in neurons simultaneously expressing yellow light-driven Halo and blue light-driven ChR2, allowing for the first time manipulations of neural synchrony without perturbation of other parameters such as spiking rates. The Halo/ChR2 system thus constitutes a powerful toolbox for multichannel photoinhibition and photostimulation of virally or transgenically targeted neural circuits without need for exogenous chemicals, enabling systematic analysis and engineering of the brain, and quantitative bioengineering of excitable cells.
Proper citation: Channelrhodopsin-2 enables optical activation of neurons (RRID:SCR_008833) Copy
Core laboratory for nucleic acid sequencing and bioinformatics. Used for research support, education, and training. Services include genomic techniques and applications, sequencing technologies, and bioinformatics analyses, writting letters of support for grant applications submitted to funding agencies. GGBC operates multiple platforms for short-, long-, and single-molecule sequencing reads (i.e., Illumina MiSeq and NextSeq, PacBio Sequel, and Oxford Nanopore MinIon).
Proper citation: Georgia Genomics and Bioinformatics Core at the University of Georgia (RRID:SCR_010994) Copy
https://site.research.utexas.edu/cbrs/
Facility provides access to and operational support for easy-to-operate equipment for sample preparation and analysis, including gel imagers, plate readers, and qPCRs. They provide training on instrument operation and grant access for independent use after completed training.
Proper citation: University of Texas at Austin Shared Instrumentation Facility (RRID:SCR_026271) Copy
Analyzer applies BD FACSymphony instrument technology to reduce background noise and increase detection sensitivity. Features low-noise electronics, high-powered lasers and tight beam spot to support immunophenotyping up to 16 colors. Enables independent analysis of large and small particles on single instrument. Optional small particle detector enables detection of small particles such as extracellular vesicles, viral particle and more. Compatible with broad portfolio of catalog and custom BD Horizon Brilliant Reagents and BD FACSDiva Software. Permits easy placement on standard lab bench with its compact format.
Proper citation: BD Biosciences: FACSymphony A1 Cell Analyzer (RRID:SCR_024830) Copy
https://www.3dhistech.com/research/pannoramic-digital-slide-scanners/pannoramic-midi/
Automatic digital slide scanner with 12 slide capacity in one run, fluorescence scanning, 9 physical filter cubes and 45 logical fluorescence channels. Powered by PANNORAMIC Scanner Software. Supports Carl Zeiss objectives, achieving up to 43x or 86x magnification and 0.087 µm/pixel resolution within the same instrument, along with advanced FISH scanning technique.
Proper citation: 3DHISTECH: PANNORAMIC MIDI II scanner (RRID:SCR_024834) Copy
http://www.med.upenn.edu/molecular/core_morphology.shtml
Core facility that provides histological services, equipment usage, and technical expertise to digestive and liver research projects.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Molecular Pathology and Imaging Core (RRID:SCR_015618) Copy
https://www.spscientific.com/AboutOurTrustedBrands/
Commercial organization located in Warminster, Pennsylvania, USA, part of SP Industries, Inc. Provides VirTis, FTS Systems, Hotpack, Hull, Genevac, and PennTech scientific equipment. Manufactures freeze drying/lyophilization, centrifugal evaporation and concentration, temperature control/thermal management, glassware washers, controlled environments, vial washing and tray loading machines., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: SP Scientific (RRID:SCR_017367) Copy
https://www.bruker.com/about-us.html
Commercial organization located in Massachusetts, USA, for scientific instruments and analytical and diagnostic solutions. Bruker equipment can be used in life science molecular research, in applied and pharma applications,microscopy, nano-analysis and industrial applications. Provider of high-performance systems for cell biology, preclinical imaging, clinical phenomics and proteomics research, clinical microbiology, and for molecular pathology research.
Proper citation: Bruker Corporation (RRID:SCR_017365) Copy
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