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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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Sutter P-2000 Laser Micropipette Puller Resource Report Resource Website 1+ mentions |
Sutter P-2000 Laser Micropipette Puller (RRID:SCR_018640) | instrument resource | Microprocessor controlled, CO2 laser based micropipette puller.Default configuration allows fabrication of micropipettes for intracellular recording, patch clamping, microinjection and microperfusion.Can store up to 100 separate programs, each consisting of up to 8 command lines. The five parameters set in each command line allow exquisite control of the micropipette taper geometry. Allows the use of wide range of glass diameters from 0.125 to 1.2 mm. | Laser Micropipette Puller, Instrument, Equipment, USEDit, ABRF | is listed by: USEDit | Commercially available | SCR_020537, SCR_020213, Model_Number_P2000 | https://www.sutter.com/manuals/P-2000_OpMan.pdf | SCR_018640 | 2025-05-01 11:05:33 | 2 | ||||||||
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Channelrhodopsin-2 enables optical activation of neurons Resource Report Resource Website 1+ mentions |
Channelrhodopsin-2 enables optical activation of neurons (RRID:SCR_008833) | Channelrhodopsin-2 enables optical activation of neurons | service resource, resource, material service resource, production service resource | Laser tool that enables neurons to be optically silenced by pulses of yellow light, the light-activated chloride pump halorhodopsin (Halo), in a paper entitled Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. Temporally precise, noninvasive control of activity in well-defined neuronal populations is a long-sought goal of systems neuroscience. We adapted for this purpose the naturally occurring algal protein Channelrhodopsin-2, a rapidly gated light-sensitive cation channel, by using lentiviral gene delivery in combination with high-speed optical switching to photostimulate mammalian neurons. We demonstrate reliable, millisecond-timescale control of neuronal spiking, as well as control of excitatory and inhibitory synaptic transmission. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. The quest to determine how precise neural activity patterns mediate computation, behavior, and pathology would be greatly aided by a set of tools for reliably activating and inactivating genetically targeted neurons, in a temporally precise and rapidly reversible fashion. Having earlier adapted a light-activated cation channel, 1channelrhodopsin-2 (ChR2), for allowing neurons to be stimulated by blue light, we searched for a complementary tool that would enable optical neuronal inhibition, driven by light of a second color. Here we report that targeting the 1codon-optimized form of the light-driven chloride pump halorhodopsin from the archaebacterium Natronomas pharaonis (hereafter abbreviated Halo) to genetically-specified neurons enables them to be silenced reliably, and reversibly, by millisecond-timescale pulses of yellow light. We show that trains of yellow and blue light pulses can drive high-fidelity sequences of hyperpolarizations and depolarizations in neurons simultaneously expressing yellow light-driven Halo and blue light-driven ChR2, allowing for the first time manipulations of neural synchrony without perturbation of other parameters such as spiking rates. The Halo/ChR2 system thus constitutes a powerful toolbox for multichannel photoinhibition and photostimulation of virally or transgenically targeted neural circuits without need for exogenous chemicals, enabling systematic analysis and engineering of the brain, and quantitative bioengineering of excitable cells. | hardware, instrument, equipment | has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; | Anonymous donor ; MIT Media Lab ; Helen Hay Whitney Foundation |
PMID:17375185 | nlx_144630 | http://channelrhodopsin.org | SCR_008833 | 2025-05-01 10:58:28 | 3 | ||||||
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Rockefeller University Bio-Imaging Resource Center Core Facility Resource Report Resource Website 10+ mentions |
Rockefeller University Bio-Imaging Resource Center Core Facility (RRID:SCR_017791) | BIRC | core facility, service resource, access service resource | Provide members of University and their visitors with wide spectrum of optical microscopy equipment and extensive training in its use. | Optical, microscopy, equipment, training, service, core | Restricted | ABRF_426 | SCR_017791 | Frits and Rita Markus Bio-Imaging Resource Center | 2025-05-01 11:04:51 | 22 | ||||||||
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Chicago University Biophysics Core Facility Resource Report Resource Website 1+ mentions |
Chicago University Biophysics Core Facility (RRID:SCR_017915) | core facility, service resource, access service resource | Core provides access to biophysics equipment, integral to research community at University of Chicago.Provides tools, training, and assistance for quantitative analysis of macromolecules and their interactions. Instruments include Seahorse XFe-96 Extracellular Flux Analyzer,Jasco J-1500 CD Spectrometer,Synergy Neo HST Plate Reader,Wyatt DAWN HELEOS II SLS,Wyatt DynaPro Plate Reader DLS,Wyatt DynaPro NanoStar DLS,HORIBA Fluorolog-3,Microcal iTC200,Molecular Imager,Bio-Rad ProteOn XPR to Biacore 8K,Agilent 8453 Spectrophotometer. Core provides staff assistance in conducting experiments. | Biophysics, equipment, tool, training, assistance, quantitative, analysis, macromolecule, interaction, spectrometer, service, core, ABRF | is listed by: ABRF CoreMarketplace | Open | ABRF_802 | SCR_017915 | BioPhysics Core Facilities | 2025-05-01 11:04:59 | 2 | ||||||||
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Brown University Molecular Pathology Core Facility Resource Report Resource Website |
Brown University Molecular Pathology Core Facility (RRID:SCR_017898) | core facility, service resource, access service resource | Core provides equipment and technical expertise for evaluation of molecular and morphological changes in cells, tissues, and organs following exposure to complex environmental contaminants. Provides equipment, including automated tissue processor, paraffin embedding center, two automated microtomes, cryostat, vibratome for soft-tissue sectioning, multiheaded light microscope with projection capabilities, system for laser capture microdissection, and slide scanner with analysis software for identification and quantification of morphological structures.Offers expertise in histopathological and immunocytochemial methods, including fixation, dehydration, embedding, sectioning, histological staining, immunolabeling, high-resolution imaging, and quantitative image analysis. Services in sample preparation, offers assistance in imaging and image analysis and provides consultation for ongoing or future research projects, training program for students and investigators who use centrally available equipment. | Pathology, equipment, technical, support, molecular, morphological, changes, cell, tissue, organ, exposure, contaminant, sample, preparation, imaging, analysis, consultation, training, service, core, ABRF | is listed by: ABRF CoreMarketplace | Open | ABRF_772 | SCR_017898 | Molecular Pathology Core | 2025-05-01 11:04:58 | 0 | ||||||||
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University of Illinois at Urbana-Champaign Core Facilities at IGB Resource Report Resource Website |
University of Illinois at Urbana-Champaign Core Facilities at IGB (RRID:SCR_017938) | core facility, service resource, access service resource | Core for biological microscopy and image analysis. Offers high-end equipment,user training,ongoing support, including experiment design and data interpretation,twenty-four hour access Services,3D Printing, Transfer Files, Image Analysis,Histology,Instrument Training. | Microscopy, image, analysis, equipment, training, data, analysis, 3D, printing, histology, service, core, ABRF | is listed by: ABRF CoreMarketplace | Restricted | ABRF_881 | SCR_017938 | Core Facilities at IGB | 2025-05-01 11:05:01 | 0 | ||||||||
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Nikon Eclipse E600 Fluorescence Microscope Resource Report Resource Website 1+ mentions |
Nikon Eclipse E600 Fluorescence Microscope (RRID:SCR_018606) | instrument resource | Microscope equipped with CFI60 infinity optical system, providing images in all applications. Incorporates specifications adopted for CFI60 series objectives, including 60 millimeter parfocal distance, 25 millimeter thread size, and standard 22 millimeter field of view. Main components of CFI60 infinity optical system include objective, tube lens to converge light beam, and eyepiece lens to enlarge intermediate image. Fluorescence microscope that has detachable substage, 12 volt 100 watt tungsten halide lamp, filter magazine, and choice of sextuple nosepiece or sextuple DIC nosepiece.Has objectives for brightfield, darkfield, Nomarski DIC, epi fluorescence, or phase contrast techniques. | Camera, Instrument, Equipment, Nikon, USEDit, ABRF | is listed by: USEDit | Commercially available | , SCR_020322, SCR_020330, Model_Number_E600, SCR_018858 | https://gsecars.uchicago.edu/wp-content/uploads/2019/06/Nikon_E600-Instruction-manual.pdf | SCR_018606 | , Nikon Eclipse E600 Microscope | 2025-05-01 11:05:33 | 2 | |||||||
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University of Melbourne Biological Optical Microscopy Platform (BOMP) Core Facility Resource Report Resource Website 1+ mentions |
University of Melbourne Biological Optical Microscopy Platform (BOMP) Core Facility (RRID:SCR_018888) | BOMP | core facility, service resource, access service resource | Core provides access to fluorescence microscopy equipment including Deltavision OMX Blaze Super Resolution (3D-SIM/SMLM), Leica SP8 inverted confocal, La Vision Ultramicroscope II Lightsheet Microscope,Nikon Andor WD spinning disk, Nikon A1R inverted confocal x2, Olympus FV-MPERS Multi Photon,Olympus FV3000 inverted confocal (live cell) ISS Fast-FLIM, Perkin Elmer Operetta High Content Imaging, Zeiss LSM800 upright Airyscan, Zeiss LSM880 upright Airyscan fast, Zeiss Elyra/LSM880 inverted (live cell), super resolution (Airyscan/SMLM). Staff can help with image analysis, super resolution microscopy, fluorescence lifetime imaging microscopy, high content imaging and light sheet microscopy techniques. | Fluorescence microscopy, microscope, instrument, equipment, image analysis, imaging microscopy, light sheet microscopy, imaging, ABRF, ABRF |
is listed by: ABRF CoreMarketplace has parent organization: University of Melbourne; Victoria; Australia |
Open | SCR_018888 | Biological Optical Microscopy Platform | 2025-05-01 11:05:47 | 2 | ||||||||
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Georgia Genomics and Bioinformatics Core at the University of Georgia Resource Report Resource Website 50+ mentions |
Georgia Genomics and Bioinformatics Core at the University of Georgia (RRID:SCR_010994) | GGBC | training service resource, core facility, service resource, access service resource | Core laboratory for nucleic acid sequencing and bioinformatics. Used for research support, education, and training. Services include genomic techniques and applications, sequencing technologies, and bioinformatics analyses, writting letters of support for grant applications submitted to funding agencies. GGBC operates multiple platforms for short-, long-, and single-molecule sequencing reads (i.e., Illumina MiSeq and NextSeq, PacBio Sequel, and Oxford Nanopore MinIon). | nucleic, acid, sequencing, labs, analysis, equipment, genomic, technique, analysis, grant, application |
is listed by: ScienceExchange is related to: University of Georgia Labs and Facilities has parent organization: University of Georgia; Georgia; USA |
Restricted | SciEx_9234 | http://www.scienceexchange.com/facilities/georgia-genomics-facility-uga, http://www.scienceexchange.com/facilities/georgia-genomics-facility-uga | SCR_010994 | Georgia Genomics & Bioinformatics Core, Georgia Genomics and Bioinformatics Core at UGA, University of Georgia Genomics Facility, Georgia Genomics and Bioinformatics Core | 2025-05-01 11:00:14 | 64 | ||||||
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DTI FiberTrak MR Clinical application Resource Report Resource Website |
DTI FiberTrak MR Clinical application (RRID:SCR_015521) | software resource, image analysis software, data processing software, resource, data analysis software, software application | Instrument and software tool used to visualize, trace, analyze, and process white matter fiber tracts of Diffusion Tensor Imaging (DTI) data in real-time. It supports pre-operative surgical planning, post-surgery evaluation, and general evaluation of fiber tracts around tumors and lesions in connection with functional areas. | white matter fiber tract, dti analysis, diffusion tensor imaging analysis, surgical preparation, surgical evaluation, hardware, instrument, equipment | Commercially available | SCR_015521 | Philips DTI FiberTrak, DTI FiberTrak | 2025-05-01 11:03:10 | 0 | ||||||||||
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StepOnePlus Real-Time PCR System Resource Report Resource Website 10+ mentions |
StepOnePlus Real-Time PCR System (RRID:SCR_015805) | software resource, data acquisition software, instrument resource, data processing software, software application | Equipment and software system that is a real-time thermal cycler for intuitive data analysis of polymerase chain reactions. It comes with analysis software, instrument control software, and a LED-based 4-color optical recording feature. | image acquisition software, genotype, real time pcr, qPCR, thermal cycler, hardware, pcr, polymerase chain reaction, instrument, equipment | Commercially available, Available for purchase, Runs on Windows | SCR_015805 | StepOnePlus, StepOnePlus™ Real-Time PCR System | 2025-05-01 11:03:21 | 34 | ||||||||||
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Luminex Amnis ImageStreamX Mk II System Resource Report Resource Website 100+ mentions |
Luminex Amnis ImageStreamX Mk II System (RRID:SCR_018589) | instrument resource | Bench top multispectral imaging flow cytometer designed for the acquisition of up to 12 channels of cellular imagery. It combines per cell information with statistical significance of sample sizes of standard flow cytometry. | Benchtop Flow Cytometer, Instrument, Equipment, imaging flow cytometer, USEDit, Luminex | is listed by: USEDit | Restricted | SCR_020244, SCR_020142, Model_Number_ImageStreamX_MkII | https://www.unthsc.edu/research/wp-content/uploads/sites/21/AMNIS-Imagestream.pdf | https://www.luminexcorp.com/imagestreamx-mk-ii/ | SCR_018589 | , Luminex ImageStream MkII Multispectral Imaging Flow Cytometer, MkII imaging flow cytometer, Luminex ImageStream MkII Flow Cytometer, Luminex Amnis ImageStream MkII Multispectral Imaging Flow Cytometer | 2025-05-01 11:05:33 | 124 | ||||||
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Biacore 3000 Real Time Biomolecular Interaction Analyzer Resource Report Resource Website 1+ mentions |
Biacore 3000 Real Time Biomolecular Interaction Analyzer (RRID:SCR_018044) | instrument resource | Biacore 3000 processing unit is an established, label-free system for detailed studies of biomolecular interactions. The system delivers comprehensive characterization of the interaction, answers questions about the rate constants, affinity, specificity, and determines the active concentration of components. The ability to recover and transfer interaction partners directly to MALDI targets for identification and further characterization makes the system highly applicable to fast identification of unknown interactants. | ABRF, Real Time Biomolecular Interaction Analyzer, GE Healthcare, instrument, equipment | is listed by: USEDit | Restricted | SCR_019676, SCR_018577, Model_Number_Biacore 3000 | https://www.ibps.sorbonne-universite.fr/ressources/documents/1/2276 Brochure-Biacore-3000.pdf |
https://www.gelifesciences.com/en/us/shop/biacore-3000-goldseal-p-02795 | SCR_018044 | BIACORE 3000 GOLDSEAL, BiaCore 3000 Surface Plasmon Resonance | 2025-05-01 11:05:05 | 2 | ||||||
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Limelight Resource Report Resource Website 10+ mentions |
Limelight (RRID:SCR_014254) | software resource, data acquisition software, time-series analysis software, data processing software, resource, data analysis software, software application | A video tracking system designed for high-throughput behavioral experiments. LimeLight can track up to 4 arenas at once and can collect images at up to 30 frames per second for one animal or up to 8 frames per second when tracking 4 arenas at once. The tracking system has 2 different hardware configurations: the 1-camera system can be used to record 1 to 4 animals at once, while for multiple animals, each one is placed in a separate arena in one quadrant of the image. The software contains productivity features such as flexible arena setup, user-defined behavior scoring, stimulus control, and various analytical functions for quantifying behavior. The program is designed for experiments such as Open Field, Plus Maze, Radial Arm Maze, Zero Maze, Novel Object Recognition, Conditioned Place Preference, and Barnes Maze. | data acquisition software, time series analysis software, data analysis software, video tracking system, behavioral experiment, high throughput, hardware, instrument, equipment | is related to: FreezeFrame | Account required | SCR_014254 | 2025-05-01 11:02:09 | 15 | ||||||||||
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Automated mouse homecage two bottle choice test project Resource Report Resource Website |
Automated mouse homecage two bottle choice test project (RRID:SCR_021457) | portal, data or information resource, instrument resource, project portal | Project related to assessing preferences by mice among fluids in their homecages.Provided system includes homecage fitted apparatus for automated, photobeam based detection of licks in two bottle choice task. Used for automated mouse homecage two bottle choice test. | Homecage fitted apparatus, licks automated detection, licks photobeam based detection, two bottle choice task, instrument, equipment, USEDit, OpenBehavior, Instrument | is listed by: OpenBehavior | Free, Freely available | SCR_021457 | Automated mouse homecage two bottle choice test | 2025-05-01 11:06:17 | 0 | |||||||||
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Rodent Activity Detector project Resource Report Resource Website |
Rodent Activity Detector project (RRID:SCR_021451) | RAD | portal, data or information resource, instrument resource, project portal | Project related to tracking and recording activity in rodent home cages.Provides device that utilizes passive infrared (PIR) sensor to detect movement in cages and logs data to microSD card. Device is wireless and battery powered, and can record data for about 3 weeks on charge. | Passive infrared sensor, detect movement in cages, logs data to microSD card, wireless device, battery powered device, record data, instrument, equipment, USEDit, OpenBehavior, Instrument | is listed by: OpenBehavior | DOI:10.1523/eneuro.0160-19.2019 | Free, Freely available | SCR_021451 | Rodent Activity Detector | 2025-05-01 11:06:17 | 0 | |||||||
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Automated Home Cage Rodent Two bottle Choice Test project Resource Report Resource Website |
Automated Home Cage Rodent Two bottle Choice Test project (RRID:SCR_021445) | portal, data or information resource, instrument resource, project portal | Project related to studies of liquid ingestive behaviors used in neuroscience to investigate reward related behavior, metabolism, and circadian biology. Provides automated home cage sipper device for monitoring liquid ingestive behavior in rodents developed by Washington University, St. Louis scientists. Homecage fitted apparatus for automated, photobeam based detection of licks in two bottle choice task. | Automated home cage sipper device, Sipper, monitoring liquid, ingestive behavior, rodents, instrument, equipment, USEDit, OpenBehavior, Instrument |
is listed by: OpenBehavior is related to: SipperViz |
DOI:10.1523/eneuro.0292-19.2019 | Free, Freely available | SCR_021445 | Automated Home Cage Rodent Two bottle Choice Test | 2025-05-01 11:06:17 | 0 | ||||||||
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University of Texas at Austin Shared Instrumentation Facility Resource Report Resource Website |
University of Texas at Austin Shared Instrumentation Facility (RRID:SCR_026271) | core facility, service resource, access service resource | Facility provides access to and operational support for easy-to-operate equipment for sample preparation and analysis, including gel imagers, plate readers, and qPCRs. They provide training on instrument operation and grant access for independent use after completed training. | ABRF, equipment, sample preparation and analysis, gel imagers, plate readers, qPCR, training on instrument operation, |
is listed by: ABRF CoreMarketplace has parent organization: University of Texas at Austin; Texas; USA |
ABRF_2996 | https://coremarketplace.org/?FacilityID=2996&citation=1 | SCR_026271 | , Shared Instrumentation Facility, The University of Texas at Austin Shared Instrumentation Facility | 2025-05-01 11:09:14 | 0 | ||||||||
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Neurogrid Resource Report Resource Website 10+ mentions |
Neurogrid (RRID:SCR_005024) | Neurogrid | instrument resource | A specialized hardware platform that will perform cortex-scale emulations while offering software-like flexibility. With sixteen 12x14 sq-mm chips (Neurocores) assembled on a 6.5x7.5 sq-in circuit board that can model a slab of cortex with up to 16x256x256 neurons - over a million! The chips are interconnected in a binary tree by 80M spike/sec links. An on-chip RAM (in each Neurocore) and an off-chip RAM (on a daughterboard, not shown) softwire vertical and horizontcal cortical connections, respectively. It provides an affordable option for brain simulations that uses analog computation to emulate ion-channel activity and uses digital communication to softwire synaptic connections. These technologies impose different constraints, because they operate in parallel and in serial, respectively. Analog computation constrains the number of distinct ion-channel populations that can be simulatedunlike digital computation, which simply takes longer to run bigger simulations. Digital communication constrains the number of synaptic connections that can be activated per secondunlike analog communication, which simply sums additional inputs onto the same wire. Working within these constraints, Neurogrid achieves its goal of simulating multiple cortical areas in real-time by making judicious choices. | simulation, neuron, cortex, synapse, analog vlsi, instrument, equipment, hardware | has parent organization: Stanford University; Stanford; California | NSF ; NIH |
PMID:17959490 | nlx_97879 | SCR_005024 | 2025-04-19 06:42:42 | 13 | |||||||
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Sartorius Resource Report Resource Website 50+ mentions |
Sartorius (RRID:SCR_003935) | SSB | commercial organization | Commercial organization that provides laboratory and process technologies and equipment. Their products and services help customers around the globe implement complex and quality-critical processes in biopharmaceutical production and laboratory environments in a time- and cost-efficient way. Sartorius operates its own production facilities in Europe, Asia and America, and also has sales offices and local representatives in more than 110 countries. | laboratory, process technology, equipment, biopharmaceutical |
is related to: Sartorius Ambr 15 Cell Culture Generation 2 is related to: Pharma-Planta Consortium provides: IncuCyte® Chemotaxis Software |
nlx_158308 | SCR_003935 | Sartorius-Stedim Biotech, Sartorius AG, Sartorius Stedim Biotech S.A., Sartorius Stedim Biotech | 2025-04-19 06:41:58 | 98 |
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