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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Beckman Coulter: L-90K Ultracentrifuge
 
Resource Report
Resource Website
Beckman Coulter: L-90K Ultracentrifuge (RRID:SCR_019651) instrument resource Ultracentrifuge is used for centrifugation of subcellular particles, virus isolations, and high purity plasmid DNA. Beckman Coulter, Centrifuge, Instrument, Equipment, Beckman Coulter, USEDit, ABRF, Commercially available https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_019651.pdf Model_Number_L90K SCR_019651 2026-08-04 09:44:34 0
Beckman Coulter: DxH 800 Hematology Analyzer
 
Resource Report
Resource Website
Beckman Coulter: DxH 800 Hematology Analyzer (RRID:SCR_019635) instrument resource DxH 800 hematology analyzer utilizes data about individual cell size, shape and structure to provide high quality results. Beckman Coulter, Hematology Analyzer, Instrument, Resource Equipment, Equipment, USEDit, Commercially available https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_019635.pdf Model_Number_DxH_800 SCR_019635 2026-08-04 09:44:36 0
Beckman Coulter: DU 530 Spectrophotometer
 
Resource Report
Resource Website
Beckman Coulter: DU 530 Spectrophotometer (RRID:SCR_019631) instrument resource This spectrophotometer functions with single cell module and supports alternative cell holders, like 16 mm test tube, 1 cm standard, 10cm rectangular turbidity, and 50uL microcell. Beckman Coulter, Spectrophotometer, Instrument, Equipment, USEDit, Commercially available https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_019631.pdf Model_Number_DU_530 SCR_019631 2026-08-04 09:44:33 0
Beckman Coulter: DiaSorin LIAISON XL Chemiluminescence Immunoassay Analyzer
 
Resource Report
Resource Website
1+ mentions
Beckman Coulter: DiaSorin LIAISON XL Chemiluminescence Immunoassay Analyzer (RRID:SCR_019630) instrument resource Chemiluminescence Immunoassay Analyzer closes care gap and addresses challenges with blood viruses and infectious diseases. Beckman Coulter, Immunoassay Analyzer, Instrument, Equipment, USEDit Commercially available https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_019630.pdf Model_Number_DiaSorin_LIAISON_XL SCR_019630 2026-08-04 09:44:34 1
G protein receptor interaction feature finding instrument
 
Resource Report
Resource Website
10+ mentions
G protein receptor interaction feature finding instrument (RRID:SCR_008343) resource, production service resource, service resource, analysis service resource Griffin (G-protein-receptor interacting feature finding instrument) is a high-throughput system to predict GPCR - G-protein coupling selectively with the input of GPCR sequence and ligand molecular weight. This system consists of two parts: 1) HMM section using family specific multiple alignment of GPCRs, 2) SVM section using physico-chemical feature vectors in GPCR sequence. G-protein coupled receptors (GPCR), which is composed of seven transmembrane helices, play a role as interface of signal transduction. The external stimulation for GPCR, induce the coupling with G-protein (Gi/o, Gq/11, Gs, G12/13) followed by different kinds of signal transduction to inner cell. About half of distributed drugs are intending to control this GPCR - G-protein binding system, and therefore this system is important research target for the development of effective drug. For this purpose, it is necessary to monitor, effectively and comprehensively, of the activation of G-protein by identifying ligand combined with GPCR. Since, at present, it is difficult to construct such biochemical experiment system, if the answers for experimental results can be prepared beforehand by using bioinformatics techniques, large progress is brought to G-protein related drug design. Previous works for predicting GPCR-G protein coupling selectivity are using sequence pattern search, statistical models, and HMM representations showed high sensitivity of predictions. However, there are still no works that can predict with both high sensitivity and specificity. In this work we extracted comprehensively the physico-chemical parameters of each part of ligand, GPCR and G-protein, and choose the parameters which have strong correlation with the coupling selectivity of G-protein. These parameters were put as a feature vector, used for GPCR classification based on SVM. drug, alignment, biochemical, bioinformatic, coupling, gpcr, g-protein, helix, instrument, interface, ligand, molecular, pattern, physico-chemical, receptor interacting, sequence, signal transduction, stimulation, svm, system, technique, transmembrane, weight, instrument, equipment, hardware, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Computational Biology Research Center Core Facility
National Institute of Advanced Industrial Science and Technology nif-0000-25210, biotools:griffin https://bio.tools/griffin SCR_008343 Griffin 2026-08-05 10:44:59 19
DTI FiberTrak MR Clinical application
 
Resource Report
Resource Website
DTI FiberTrak MR Clinical application (RRID:SCR_015521) data processing software, image analysis software, software application, data analysis software, software resource, resource Instrument and software tool used to visualize, trace, analyze, and process white matter fiber tracts of Diffusion Tensor Imaging (DTI) data in real-time. It supports pre-operative surgical planning, post-surgery evaluation, and general evaluation of fiber tracts around tumors and lesions in connection with functional areas. white matter fiber tract, dti analysis, diffusion tensor imaging analysis, surgical preparation, surgical evaluation, hardware, instrument, equipment Commercially available SCR_015521 Philips DTI FiberTrak, DTI FiberTrak 2026-08-05 10:46:25 0
Thermo Fisher: StepOnePlus Real-Time PCR System
 
Resource Report
Resource Website
10+ mentions
Thermo Fisher: StepOnePlus Real-Time PCR System (RRID:SCR_015805) data processing software, data acquisition software, software application, instrument resource, software resource Equipment and software system that is a real-time thermal cycler for intuitive data analysis of polymerase chain reactions. It comes with analysis software, instrument control software, and a LED-based 4-color optical recording feature. image acquisition software, genotype, real time pcr, qPCR, thermal cycler, hardware, pcr, polymerase chain reaction, instrument, equipment Commercially available, Available for purchase, Runs on Windows SCR_015805 StepOnePlus, StepOnePlus™ Real-Time PCR System 2026-08-05 10:46:30 47
Limelight
 
Resource Report
Resource Website
10+ mentions
Limelight (RRID:SCR_014254) data processing software, data acquisition software, software application, data analysis software, time-series analysis software, software resource, resource A video tracking system designed for high-throughput behavioral experiments. LimeLight can track up to 4 arenas at once and can collect images at up to 30 frames per second for one animal or up to 8 frames per second when tracking 4 arenas at once. The tracking system has 2 different hardware configurations: the 1-camera system can be used to record 1 to 4 animals at once, while for multiple animals, each one is placed in a separate arena in one quadrant of the image. The software contains productivity features such as flexible arena setup, user-defined behavior scoring, stimulus control, and various analytical functions for quantifying behavior. The program is designed for experiments such as Open Field, Plus Maze, Radial Arm Maze, Zero Maze, Novel Object Recognition, Conditioned Place Preference, and Barnes Maze. data acquisition software, time series analysis software, data analysis software, video tracking system, behavioral experiment, high throughput, hardware, instrument, equipment is related to: FreezeFrame Account required SCR_014254 2026-08-05 10:46:06 15
Agilent: 3100 OFFGEL Fractionator
 
Resource Report
Resource Website
1+ mentions
Agilent: 3100 OFFGEL Fractionator (RRID:SCR_018433) instrument resource Agilent 3100 OFFGEL Fractionator performs isoelectric focusing of proteins or peptides in immobilized pH gradient (IPG) gel strips. Fractionator, Instrument, Equipment, Electrophoresis, Agilent, USEDit, ABRF, is listed by: USEDit https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_018433.pdf SCR_018442, SCR_019388 https://www.agilent.com/Library/usermanuals/Public/G3100-90001_OFFGEL_UserManual_ebook.pdf SCR_018433 Agilent 3100 OFFGEL Fractionator 2026-08-05 10:47:03 1
Thermo Fisher: Applied Biosystems: GeneAmp 9700 PCR Thermocycler System
 
Resource Report
Resource Website
10+ mentions
Thermo Fisher: Applied Biosystems: GeneAmp 9700 PCR Thermocycler System (RRID:SCR_018436) instrument resource Automated PCR instrument for automated amplification of nucleic acids with Polymerase Chain Reaction. It has reaction volumes of up to 50 uL and sample temperature range of 4 to 99.9 C. Matrix Assisted Laser Desorption Ionization Time of Flight Instrument, Instrument, Equipment, Applied Biosystems, USEDit, ABRF is listed by: USEDit https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_018436.pdf SCR_018448, SCR_019577, Model_Number_9700 https://assets.thermofisher.com/TFS-Assets/LSG/manuals/cms_040970.pdf SCR_018436 2026-08-05 10:47:01 13
American Optical: 860 Sliding Microtome
 
Resource Report
Resource Website
American Optical: 860 Sliding Microtome (RRID:SCR_018434) instrument resource THIS REOURCE IS NO LONGER IN SERVICE. Documented on September 29,2023. Sliding microtome used for cutting hard objects such as bone, wood, frozen celloidin, and paraffin preparations. Cutting thickness is adjustable from 1 to 40 microns. Sliding Microtome, Instrument, Equipment, American Optical, USEDit, ABRF is listed by: USEDit THIS REOURCE IS NO LONGER IN SERVICE https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_018434.pdf SCR_018451, SCR_019570 https://rankinbiomed.com/wp-content/uploads/AO-860-Sliding-Microtome-Manual.pdf SCR_018434 2026-08-05 10:47:02 0
Atago: PAL-10S Pocket Refractometer
 
Resource Report
Resource Website
Atago: PAL-10S Pocket Refractometer (RRID:SCR_018439) instrument resource Digital hand held pocket refractometer that measures urine specific gravity. It has measurement temperature of 10 to 35 C and sample volume of 0.3ml. Pocket Refractometer, Instrument, Equipment, Atago, USEDit, ABRF is listed by: USEDit Commercially available https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_018439.pdf SCR_018449, SCR_019583, Model_Number_PAL_10S https://www.novatech-usa.com/pdf/Atago%20PAL-10S%20Refractometer%20Datasheet.pdf SCR_018439 2026-08-05 10:47:01 0
Sutter: P-2000 Laser Micropipette Puller
 
Resource Report
Resource Website
1+ mentions
Sutter: P-2000 Laser Micropipette Puller (RRID:SCR_018640) instrument resource Microprocessor controlled, CO2 laser based micropipette puller.Default configuration allows fabrication of micropipettes for intracellular recording, patch clamping, microinjection and microperfusion.Can store up to 100 separate programs, each consisting of up to 8 command lines. The five parameters set in each command line allow exquisite control of the micropipette taper geometry. Allows the use of wide range of glass diameters from 0.125 to 1.2 mm. Laser Micropipette Puller, Instrument, Equipment, USEDit, ABRF is listed by: USEDit Commercially available SCR_020537, SCR_020213, Model_Number_P2000 https://www.sutter.com/manuals/P-2000_OpMan.pdf SCR_018640 2026-08-05 10:47:05 3
HORNET CENTER FOR AUTONOMIC NERVE RECORDING AND STIMULATION SYSTEMS
 
Resource Report
Resource Website
HORNET CENTER FOR AUTONOMIC NERVE RECORDING AND STIMULATION SYSTEMS (RRID:SCR_023681) CARSS software repository, software resource Parylene MEA Fabrication is related to SPARC. Repository for standard fabrication procedure for Parylene C microelectrode arrays and similar devices. Instrument, equipment, device, Parylene MEA Fabrication, microelectrode arrays, Parylene C microelectrode arrays is related to: SPARC Portal
is related to: SPARC Request
Free, Freely available SCR_023681 2026-08-05 10:47:53 0
Channelrhodopsin-2 enables optical activation of neurons
 
Resource Report
Resource Website
1+ mentions
Channelrhodopsin-2 enables optical activation of neurons (RRID:SCR_008833) Channelrhodopsin-2 enables optical activation of neurons resource, production service resource, service resource, material service resource Laser tool that enables neurons to be optically silenced by pulses of yellow light, the light-activated chloride pump halorhodopsin (Halo), in a paper entitled Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. Temporally precise, noninvasive control of activity in well-defined neuronal populations is a long-sought goal of systems neuroscience. We adapted for this purpose the naturally occurring algal protein Channelrhodopsin-2, a rapidly gated light-sensitive cation channel, by using lentiviral gene delivery in combination with high-speed optical switching to photostimulate mammalian neurons. We demonstrate reliable, millisecond-timescale control of neuronal spiking, as well as control of excitatory and inhibitory synaptic transmission. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. The quest to determine how precise neural activity patterns mediate computation, behavior, and pathology would be greatly aided by a set of tools for reliably activating and inactivating genetically targeted neurons, in a temporally precise and rapidly reversible fashion. Having earlier adapted a light-activated cation channel, 1channelrhodopsin-2 (ChR2), for allowing neurons to be stimulated by blue light, we searched for a complementary tool that would enable optical neuronal inhibition, driven by light of a second color. Here we report that targeting the 1codon-optimized form of the light-driven chloride pump halorhodopsin from the archaebacterium Natronomas pharaonis (hereafter abbreviated Halo) to genetically-specified neurons enables them to be silenced reliably, and reversibly, by millisecond-timescale pulses of yellow light. We show that trains of yellow and blue light pulses can drive high-fidelity sequences of hyperpolarizations and depolarizations in neurons simultaneously expressing yellow light-driven Halo and blue light-driven ChR2, allowing for the first time manipulations of neural synchrony without perturbation of other parameters such as spiking rates. The Halo/ChR2 system thus constitutes a powerful toolbox for multichannel photoinhibition and photostimulation of virally or transgenically targeted neural circuits without need for exogenous chemicals, enabling systematic analysis and engineering of the brain, and quantitative bioengineering of excitable cells. hardware, instrument, equipment has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; Anonymous donor ;
MIT Media Lab ;
Helen Hay Whitney Foundation
PMID:17375185 nlx_144630 http://channelrhodopsin.org SCR_008833 2026-08-05 10:45:08 3
Automated mouse homecage two bottle choice test project
 
Resource Report
Resource Website
Automated mouse homecage two bottle choice test project (RRID:SCR_021457) data or information resource, project portal, instrument resource, portal Project related to assessing preferences by mice among fluids in their homecages.Provided system includes homecage fitted apparatus for automated, photobeam based detection of licks in two bottle choice task. Used for automated mouse homecage two bottle choice test. Homecage fitted apparatus, licks automated detection, licks photobeam based detection, two bottle choice task, instrument, equipment, USEDit, OpenBehavior, Instrument is listed by: OpenBehavior Free, Freely available SCR_021457 Automated mouse homecage two bottle choice test 2026-08-05 10:47:26 0
Rodent Activity Detector project
 
Resource Report
Resource Website
Rodent Activity Detector project (RRID:SCR_021451) RAD data or information resource, project portal, instrument resource, portal Project related to tracking and recording activity in rodent home cages.Provides device that utilizes passive infrared (PIR) sensor to detect movement in cages and logs data to microSD card. Device is wireless and battery powered, and can record data for about 3 weeks on charge. Passive infrared sensor, detect movement in cages, logs data to microSD card, wireless device, battery powered device, record data, instrument, equipment, USEDit, OpenBehavior, Instrument is listed by: OpenBehavior DOI:10.1523/eneuro.0160-19.2019 Free, Freely available SCR_021451 Rodent Activity Detector 2026-08-05 10:47:26 0
Automated Home Cage Rodent Two bottle Choice Test project
 
Resource Report
Resource Website
Automated Home Cage Rodent Two bottle Choice Test project (RRID:SCR_021445) data or information resource, project portal, instrument resource, portal Project related to studies of liquid ingestive behaviors used in neuroscience to investigate reward related behavior, metabolism, and circadian biology. Provides automated home cage sipper device for monitoring liquid ingestive behavior in rodents developed by Washington University, St. Louis scientists. Homecage fitted apparatus for automated, photobeam based detection of licks in two bottle choice task. Automated home cage sipper device, Sipper, monitoring liquid, ingestive behavior, rodents, instrument, equipment, USEDit, OpenBehavior, Instrument is listed by: OpenBehavior
is related to: SipperViz
DOI:10.1523/eneuro.0292-19.2019 Free, Freely available SCR_021445 Automated Home Cage Rodent Two bottle Choice Test 2026-08-05 10:47:26 0
Rockefeller University Bio-Imaging Resource Center Core Facility
 
Resource Report
Resource Website
10+ mentions
Rockefeller University Bio-Imaging Resource Center Core Facility (RRID:SCR_017791) BIRC access service resource, service resource, core facility Provide members of University and their visitors with wide spectrum of optical microscopy equipment and extensive training in its use. Optical, microscopy, equipment, training, service, core Restricted ABRF_426 SCR_017791 Frits and Rita Markus Bio-Imaging Resource Center 2026-08-05 10:46:57 28
Chicago University Biophysics Core Facility
 
Resource Report
Resource Website
1+ mentions
Chicago University Biophysics Core Facility (RRID:SCR_017915) access service resource, service resource, core facility Core provides access to biophysics equipment, integral to research community at University of Chicago.Provides tools, training, and assistance for quantitative analysis of macromolecules and their interactions. Instruments include Seahorse XFe-96 Extracellular Flux Analyzer,Jasco J-1500 CD Spectrometer,Synergy Neo HST Plate Reader,Wyatt DAWN HELEOS II SLS,Wyatt DynaPro Plate Reader DLS,Wyatt DynaPro NanoStar DLS,HORIBA Fluorolog-3,Microcal iTC200,Molecular Imager,Bio-Rad ProteOn XPR to Biacore 8K,Agilent 8453 Spectrophotometer. Core provides staff assistance in conducting experiments. Biophysics, equipment, tool, training, assistance, quantitative, analysis, macromolecule, interaction, spectrometer, service, core, ABRF is listed by: ABRF CoreMarketplace Open ABRF_802 SCR_017915 BioPhysics Core Facilities 2026-08-05 10:46:54 8

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