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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PLINK/SEQ
 
Resource Report
Resource Website
50+ mentions
PLINK/SEQ (RRID:SCR_013193) software application, software toolkit, software resource, software library An open-source C/C++ library for working with human genetic variation data. The specific focus is to provide a platform for analytic tool development for variation data from large-scale resequencing projects, particularly whole-exome and whole-genome studies. However, the library could in principle be applied to other types of genetic studies, including whole-genome association studies of common SNPs. (entry from Genetic Analysis Software) gene, genetic, genomic, c/c++, r, macos, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: PLINK
has parent organization: Harvard University; Cambridge; United States
Open unspecified license nlx_154213, biotools:plink-seq https://bio.tools/plink-seq SCR_013193 2026-08-04 09:43:09 77
Gwyddion
 
Resource Report
Resource Website
1000+ mentions
Gwyddion (RRID:SCR_015583) data processing software, software application, software resource, data analysis software Modular program for SPM (scanning probe microscopy) data visualization and analysis. Primarily it is intended for the analysis of height fields obtained by scanning probe microscopy techniques (AFM, MFM, STM, SNOM/NSOM) and it supports a lot of SPM data formats. However, it can be used for general height field and (greyscale) image processing, for instance for the analysis of profilometry data or thickness maps from imaging spectrophotometry. spm data analysis, spm data visualization, height field analysis is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
Czech Metrology Institute Department of Nanometrology DOI:10.2478/s11534-011-0096-2 Open source OMICS_07548 https://sources.debian.org/src/gwyddion/ SCR_015583 2026-08-04 09:43:42 1510
PASA
 
Resource Report
Resource Website
500+ mentions
PASA (RRID:SCR_014656) data processing software, data analysis software, software resource, sequence analysis software, software application Gene structure annotation and analysis tool that uses spliced alignments of expressed transcript sequences to automatically model gene structures. It also incorporates gene structures based on transcript alignments into existing gene structure annotations. It is one component of a larger eukayotic annotation pipeline implemented at the Broad Institute. gene structure, annotation, gene structure analysis tool, spliced alignment, transcript sequence, bio.tools is used by: BRO_annotation
is listed by: Debian
is listed by: bio.tools
DOI:10.1093/nar/gkg770 Available for download biotools:PASA https://bio.tools/PASA SCR_014656 Program to Assemble Spliced Alignments (PASA), Program to Assemble Spliced Alignments 2026-08-04 09:43:30 999
Molecular Dynamics Workflow (BioKepler)
 
Resource Report
Resource Website
1+ mentions
Molecular Dynamics Workflow (BioKepler) (RRID:SCR_014389) data processing software, software application, software resource, workflow software A workflow for running molecular dynamics simulations. It can be used for all-atom molecular dynamic simulations, which involve five steps of minimization, one step of heating, three steps of equilibration, and one or more instances of production. The input is a set of directories that include the MD simulation input scripts, system topology and coordinate files. Output files are list of plots, simulation trajectories, intermediate files, restart files, and the like. workflow, MD, molecular dynamics, simulation, software, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: bioKepler
has parent organization: University of California at San Diego; California; USA
NIGMS P41GM103426 Requires Linux biotools:ambergpumdsimulation http://nbcr.ucsd.edu/data/downloads/workflows/, https://bio.tools/ambergpumdsimulation SCR_014389 Molecular Dynamics Workflow, AmberGPUMDSimulation, Molecular Dynamics Workflow Software, Amber GPUMD Simulation 2026-08-04 09:43:25 1
tximport
 
Resource Report
Resource Website
50+ mentions
tximport (RRID:SCR_016752) data processing software, software application, software resource, data analysis software Software R package for importing pseudoaligned reads into R for use with downstream differential expression analysis. Used for import and summarize transcript level estimates for transcript and gene level analysis. pseudoaligned, reads, R, differential, expression, analysis, gene, transcript, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
works with: edgeR
works with: DESeq2
SNSF 143883;
European Commission ;
NCI T32 CA009337
DOI:10.12688/f1000research.7563.1 Free, Available for download, Freely available biotools:tximport https://bioconductor.org/packages/tximport/, https://bioconductor.org/packages/devel/bioc/vignettes/tximport/inst/doc/tximport.html, https://github.com/F1000Research/tximport, https://bio.tools/tximport https://zenodo.org/record/35123#.W_w3behKiM8 SCR_016752 tximport v1.4.0 2026-08-04 09:43:59 91
Nephele
 
Resource Report
Resource Website
10+ mentions
Nephele (RRID:SCR_016595) data analysis service, analysis service resource, software resource, production service resource, service resource, web application Cloud based platform for simplified, standardized and reproducible microbiome data analysis. Allows users to process microbiome datasets through pipelines of existing software tools. microbiome, datasets, process, analyze, metagenome, sequencing, data, bio.tools uses: mothur
uses: QIIME
uses: biobakery
uses: A5-miseq
is listed by: NIAID
is listed by: bio.tools
is listed by: Debian
has parent organization: OCICB
NIH Department of Health and Human Services GS35F0373X PMID:29028892 Free, Available for download, Freely available biotools:nephele https://github.com/niaid/Nephele, https://bio.tools/nephele SCR_016595 2026-08-04 09:43:56 27
ngsRelate
 
Resource Report
Resource Website
1+ mentions
ngsRelate (RRID:SCR_016588) data processing software, software application, software resource, data analysis software Software tool for estimating pairwise relatedness from next-generation sequencing data. estimating, pairwise, relatedness, next, generation, sequencing, data, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
Danish National Research Foundation ;
Danish Council for Independent Research
PMID:26323718 Free, Available for download, Freely available biotools:ngsRelateV2, biotools:ngsrelate https://bio.tools/ngsRelateV2, https://bio.tools/ngsrelate http://www.popgen.dk/software/index.php?title=NgsRelate&oldid=694 SCR_016588 ngsRelateV2 2026-08-04 09:43:56 6
Computational Structural Biology Toolbox
 
Resource Report
Resource Website
Computational Structural Biology Toolbox (RRID:SCR_016065) CSB software toolkit, software resource, software library Software package as an application framework and a Python class library. It is designed for reading, storing and analyzing biomolecular structures in a variety of formats with rich support for statistical analyses. software, library, Python, reading, storing, analysis, biomolecular, variety, statistical, analysis, bioinformatic is listed by: Debian
is listed by: OMICtools
Deutsche Forschungsgemeinschaft (DFG) grant HA 5918/1-1;
Max Planck Society
PMID:22942023 Free, Available for download OMICS_09827 https://sources.debian.org/src/csb/ SCR_016065 Computational Structural Biology Toolbox (CSB), CSB Toolbox 2026-08-04 09:43:48 0
HiC-Pro
 
Resource Report
Resource Website
100+ mentions
HiC-Pro (RRID:SCR_017643) data processing software, software application, software resource, workflow software Software tool as optimized and flexible pipeline for Hi-C data processing. Used to process Hi-C data, from raw fastq files, paired end Illumina data, to normalized contact maps. Hi-C, data, raw, fastq, file, paired, Illumina, normalized, contact, map, bio.tools is listed by: Debian
is listed by: bio.tools
France Genomique National infrastructure ;
Labex Deep ;
European Research Coucil ;
ERC Advanced Investigator award ;
European Commission ;
ABS4NGS project ;
National Human Genome Research Institute ;
Paris Alliance of Cancer Research Institutes ;
Howard Hughes Medical Institute
PMID:26619908 Free, Available for download, Freely available biotools:hic-pro https://bio.tools/hic-pro SCR_017643 2026-08-04 09:44:12 206
OrthoFinder
 
Resource Report
Resource Website
1000+ mentions
OrthoFinder (RRID:SCR_017118) data processing software, software application, software resource, data analysis software Software Python application for comparative genomics analysis. Finds orthogroups and orthologs, infers rooted gene trees for all orthogroups and identifies all of gene duplcation events in those gene trees, infers rooted species tree for species being analysed and maps gene duplication events from gene trees to branches in species tree, improves orthogroup inference accuracy. Runs set of protein sequence files, one per species, in FASTA format. comparative, genomic, analysis, find, orthogroup, ortholog, infer, gene, tree, duplicate, accuracy, protein, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Bill and Melinda Gates Foundation ;
UKAID
PMID:26243257
DOI:10.1101/466201
Free, Available for download, Freely available biotools:OrthoFinder, OMICS_09733, BioTools:OrthoFinder https://bio.tools/OrthoFinder, https://bio.tools/OrthoFinder, https://bio.tools/OrthoFinder SCR_017118 OrthoFinder2, OrthoFinder 2026-08-04 09:44:04 2899
scanpy
 
Resource Report
Resource Website
100+ mentions
scanpy (RRID:SCR_018139) data processing software, software application, software resource, data analysis software Software Python tool for large scale single cell gene expression data analysis. Integrates analysis possibilities of established R-based frameworks, provides pre processing, visualization, graph-drawing and diffusion maps, clustering, identification of marker genes for clusters via differential expression tests and pseudo temporal ordering via diffusion pseudo time. Large scale, single cell, gene expression, data analysis, R, pre processing, visualization, graph drawing, diffusion map, clustering, marker gene, differential expression test, bio.tools uses: BBKNN
is used by: triku
is used by: MUON
is listed by: Debian
is listed by: bio.tools
is related to: Anndata
has plug in: infercnvpy
Helmholtz Postdoc Programme ;
German Research Foundation
PMID:29409532 Free, Available for download, Freely available biotools:scanpy, BioTools:scanpy https://icb-scanpy.readthedocs-hosted.com/en/stable/, https://bio.tools/scanpy, https://bio.tools/scanpy, https://bio.tools/scanpy SCR_018139 Single Cell Analysis in Python 2026-08-04 09:44:16 221
Drop-seq tools
 
Resource Report
Resource Website
50+ mentions
Drop-seq tools (RRID:SCR_018142) data processing software, software application, software resource, data analysis software Software Java tools for analyzing Drop-seq data. Used to analyze gene expression from thousands of individual cells simultaneously. Analyzes mRNA transcripts while remembering origin cell transcript. Simultaneous analysis, Drop-seq data, gene expression, thousands individual cells is listed by: Debian
has parent organization: Broad Institute
Stanley Center for Psychiatric Research ;
MGH Psychiatry Residency Research Program ;
Stanley-MGH Fellowship in Psychiatric Neuroscience ;
Stewart Trust Fellows Award ;
Simons Foundation ;
NHGRI P50 HG006193;
Klarman Cell Observatory ;
NIMH U01 MH105960;
NIMH R25 MH094612;
NICHD F32 HD075541;
NSF ECS 0335765;
NSF DMR 1310266;
NSF DMR 1420570
PMID:26000488 https://sources.debian.org/src/drop-seq-tools/ SCR_018142 Droplet sequencing tools, Droplet sequencing data analysis software tools 2026-08-04 09:44:16 94
DrivAER
 
Resource Report
Resource Website
1+ mentions
DrivAER (RRID:SCR_019076) data processing software, software application, software resource, data analysis software Software tool as method for identification of driving transcriptional programs based on AutoEncoder derived Relevance scores. Infers relevance scores for transcriptional programs with respect to specified outcomes of interest in single-cell RNA sequencing data, such as psuedotemporal ordering or disease status.Used for manifold interpretation in scRNA-seq data. Manifold interpretation, scRNAseq data, relevance scores infering, transcriptional program, psuedotemporal ordering, disease status, data, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:drivaer https://bio.tools/drivaer SCR_019076 Driving transcriptional programs using AutoEncoder based Relevance scores 2026-08-04 09:44:28 1
Epigenomics Workflow on Galaxy and Jupyter
 
Resource Report
Resource Website
1+ mentions
Epigenomics Workflow on Galaxy and Jupyter (RRID:SCR_017544) data processing software, data analysis software, workflow, software resource, training material, software application, narrative resource, data or information resource Software tool as epigenomics analysis pipeline for analysis of ChIP-Seq and RNA-Seq data using Docker images containing Galaxy and Jupyter. Epigenomic, analysis, pipeline, ChIP-Seq, RNA-Seq, data, Galaxy, Jupyter, bio.tools is listed by: bio.tools
is listed by: Debian
Agencia Estatal de Investigación of Spain SEV-2016-0672 (2017-2021) Free, Available for download, Freely available biotools:Epigenomics_Workflow_on_Galaxy_and_Jupyter https://zenodo.org/record/3298029, https://bio.tools/Epigenomics_Workflow_on_Galaxy_and_Jupyter SCR_017544 REA pipeline 2026-08-04 09:44:09 2
IMGT HighV-QUEST
 
Resource Report
Resource Website
10+ mentions
IMGT HighV-QUEST (RRID:SCR_018196) data processing software, portal, alignment software, analysis service resource, software resource, software application, image analysis software, production service resource, service resource, data or information resource Next generation B and T cell sequence alignment and characterization online surface by IMGT. Web portal for immunoglobulin (IG) or antibody and T cell receptor (TR) analysis from NGS high throughput and deep sequencing. Next generation sequencing, B cell, T cell, sequence alignment, immunoglobulin, antibody, T cell receptor, analysis, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
NHMRC ;
MESR ;
CNRS ;
Université Montpellier 2 ;
France ;
GENCI
PMID:22647994
PMID:23995877
PMID:22665256
Restricted biotools:IMGt_HighV-QUESt https://bio.tools/IMGT_HighV-QUEST SCR_018196 IMGT/HighV QUEST, IMGT/HighV-QUEST, IMGT web portal 2026-08-04 09:44:18 11
PM4NGS
 
Resource Report
Resource Website
1+ mentions
PM4NGS (RRID:SCR_019164) data processing software, data analysis software, data management software, software resource, software application, workflow software, software toolkit Software tool to generate standard organizational structure for Next Generation Sequencing data analysis. Includes directory structure for project, several Jupyter notebooks for data management and CWL workflows for pipeline execution. NGS workflow, standard organizational structure generation, Next Generation Sequencing data, NGS data analysis, NGS data analysis workflow, data integration, Jupyter notebook, CWL format, bio.tools is listed by: bio.tools
is listed by: Debian
Intramural Research Program of the National Library of Medicine NIH DOI:10.7490/f1000research.1117155.1 Free, Freely available biotools:pm4ngs https://bio.tools/pm4ngs SCR_019164 Project Manager for Next Generation Sequencing 2026-08-04 09:44:30 1
ComplexHeatmap
 
Resource Report
Resource Website
1000+ mentions
ComplexHeatmap (RRID:SCR_017270) data processing software, data analysis software, software resource, software application, data visualization software Software package to arrange multiple heatmaps and support various annotation graphics. Used to visualize associations between different sources of data sets and to reveal potential patterns. arrange, multiple, heatmap, visualize, data, pattern, genomic, dataset, bio.tools is listed by: Debian
is listed by: bio.tools
German Cancer Research Center-Heidelberg Center for Personalized Oncology ;
BMBF
PMID:27207943 Free, Available for download, Freely available biotools:complexheatmap https://github.com/jokergoo/ComplexHeatmap, https://bio.tools/complexheatmap SCR_017270 2026-08-04 09:44:07 3266
SWISS-MODEL
 
Resource Report
Resource Website
1000+ mentions
SWISS-MODEL (RRID:SCR_018123) web service, software resource, data access protocol, service resource, data or information resource Software tool as fully automated protein structure homology modeling server, accessible via ExPASy web server, or from program DeepView Swiss Pdb-Viewer. Structural bioinformatics web-server dedicated to homology modeling of 3D protein structures. Used to make protein modelling accessible to all biochemists and molecular biologists. 3D protein structure, homology modeling server, protein modeling, structural bioinformatics, automated comparative modeling, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: ExPASy Bioinformatics Resource Portal
is related to: Swiss-PdbViewerDeepViewv4.0
has parent organization: University of Basel; Basel; Switzerland
provides: SWISS-MODEL Repository
PMID:12824332 Free, Freely available biotools:swiss-model_workspace, biotools:swiss_model https://bio.tools/swiss_model, https://bio.tools/swiss-model_workspace SCR_018123 2026-08-04 09:44:17 2796
SIGNOR
 
Resource Report
Resource Website
10+ mentions
SIGNOR (RRID:SCR_018485) storage service resource, data repository, service resource, database, data or information resource Software application to organize and store in structured format signaling information published in scientific literature. Information is stored as binary causative relationships between biological entities and can be represented graphically as activity flow. Each relationship is linked to literature reporting experimental evidence. Each node is annotated with chemical inhibitors that modulate its activity. Signaling information is mapped to human proteome. SIGNOR 2.0 stores manually annotated causal relationships between proteins and other biologically relevant entities including chemicals, phenotypes, complexes, etc with compliance to FAIR data principles. Signal transduction data, signaling information, published data collection, activity flow, chemical inhibitor, human proteome, manually annotated data, protein, protein relationship, FAIR data, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: REDIportal
Italian Association for Cancer Research ;
ELIXIR-IIB ;
Italian Node of the European ELIXIR infrastructure ;
EMBL-EBI
PMID:31665520 Free, Available for download, Freely available biotools:signor https://bio.tools/signor SCR_018485 SIGnaling Network Open Resource, SIGNOR 2.0 2026-08-04 09:44:21 40
OptiType
 
Resource Report
Resource Website
10+ mentions
OptiType (RRID:SCR_022279) data processing software, software application, software resource, data analysis software Software tool for precision HLA typing from next generation sequencing data. Precision HLA typing, next generation sequencing data, HLA typing, NGS data is listed by: Debian
is listed by: OMICtools
German Research Foundation ;
German Federal Ministry of Education and Research
PMID:25143287 Free, Available for download, Freely available OMICS_05461 https://sources.debian.org/src/optitype/ SCR_022279 2026-08-04 09:45:03 44

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