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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MGH Confocal Microscope Core
 
Resource Report
Resource Website
1+ mentions
MGH Confocal Microscope Core (RRID:SCR_009921) access service resource, core facility, service resource Core facility that provides the following services: Double- and triple-labeling experiments, Acquisition of high-resolution images: 2048 x 2048 pixels, Single molecule visualization, allowing dynamic observation and functional analyses of both in vivo and living cells, Total internal reflection fluorescence experiments (TIRF).

This Core consists of a Zeiss LSM 5 Pascal laser confocal microscope with a Zeiss RGB vario laser module and Nikon C1 Confocal/TIRF System with 3 PMT. A Zeiss Axiovert 200 fully motorized light microscope is available with fluorescence, bright-field, phase-contrast and Nomarski (DIC) capabilities. Image acquisition and analyses are performed using Zeiss LSM 5 Pascal Confocal Microscopy Software (Release 3.2) on 2 workstations. Zeiss Physiology software is available also. Live cell imaging is available using a Zeiss temperature controller with custom chamber and heating stage. The Nikon C1 Confocal/TIRF System fully motorized Nikon Eclipse Ti microscope is available with fluorescence, bright-field and TIRF capabilities. Imaging acquisition and analyses are performed using EZ-C1 and NIC-Elements Software.
immunofluorescence microscopy assay, imaging technique is listed by: Eagle I nlx_156388 http://www.partners.org/researchcores/confocal/confocal_neuroscience_MGH.asp, http://www2.massgeneral.org/ncs/neuro_core_ConfocalMicroscope.htm SCR_009921 2026-08-12 10:50:06 2
MGH CCIB DNA Sequencing Core
 
Resource Report
Resource Website
1+ mentions
MGH CCIB DNA Sequencing Core (RRID:SCR_009915) access service resource, core facility, service resource Core facility that provides the following services: DNA sequencing service, High volume DNA sequencing, Plasmid verification and primer walking service, PCR purification service, Microsatellite analysis.

The DNA Sequencing Core at the Massachusetts General Hospital functions both as a small-scale sequencing facility and a high-throughput center for large-scale sequencing projects.
dna sequencing is listed by: Eagle I nlx_156380 http://www.partners.org/researchcores/DNA%20Synthesis/ccib_dna_mgh.asp, https://dnacore.mgh.harvard.edu/, http://ccib.mgh.harvard.edu/dna_core SCR_009915 2026-08-12 10:50:05 2
MSU Microscopy Core Facility
 
Resource Report
Resource Website
1+ mentions
MSU Microscopy Core Facility (RRID:SCR_009943) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 22, 2025. Core facility that provides the following services: Microscopy facility training and access.

The Center for Biofilm Engineering Microscopy Facility is a research-only facility on the MSU campus, located on the third floor of the EPS building. The Microscopy Facilities Manager trains and assists faculty, research staff and students with capturing images of samples via optical microscopy and fluorescent confocal microscopy. The microscopy facilities include three separate laboratories - the Optical Microscopy Lab, the Confocal Microscopy Lab, and the Microscope Resource Room and Digital Imaging Lab. Large inventory of fluorescent stains. Inquire for availability, applications and collaborations.
imaging assay, digital imaging, immunofluorescence microscopy assay, immunohistochemistry assay, light microscopy, confocal microscopy is listed by: Eagle I
has parent organization: Montana State University
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156412 http://cores.montana.edu/index.php?page=microscopy SCR_009943 2026-08-12 10:50:08 1
OHSU Flow Cytometry and Monoclonal Antibody Shared Resource Core Facility
 
Resource Report
Resource Website
10+ mentions
OHSU Flow Cytometry and Monoclonal Antibody Shared Resource Core Facility (RRID:SCR_009974) access service resource, core facility, service resource Core facility that provides the following services: Analytical flow cytometry service, Cell sorting service, Flow cytometry data analysis service, Grant preparation support service, Flow cytometry instrument training, Flow cytometry consultation service. The OHSU Flow Cytometry Shared Resource (FCSR) has operated as a core resource for OHSU Knight Cancer Institute members since 1996 and provides advanced flow cytometry instrumentation, technical expertise and technical services. The FCSR also provides training in data interpretation, experiment design and routine operation to researchers, offering an additional cost-saving option of doing some of the work themselves. Finally, this resource saves valuable investigator time by analyzing specimens and preparing them, if needed. ABRF, USEDit, flow cytometry assay, fluorescence activated cell sorting (facs), flow cytometry immunoassay, cell separation, atomic mass spectrometry is listed by: ABRF CoreMarketplace
has parent organization: Oregon Health and Science University; Oregon; USA
Knight NCI Cancer Center Restricted nlx_156442, ABRF_1553 https://coremarketplace.org/?FacilityID=1553&citation=1 http://ohsu.eagle-i.net/i/0000012b-1660-76b7-79a3-373680000000 SCR_009974 OHSU Flow Cytometry and Monoclonal Antibody Shared Resource, OHSU Flow Cytometry Shared Resource, Flow Cytometry Share Resource, OHSU Flow Cytometry Core Facility, OHSU Flow Cytometry Core 2026-08-12 10:50:09 22
Oregon Clinical and Translational Research Institute Biomedical Informatics Program
 
Resource Report
Resource Website
1+ mentions
Oregon Clinical and Translational Research Institute Biomedical Informatics Program (RRID:SCR_009965) OCTRI BMIP, BMIP access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility provides the following services: Data Management Consultation, Research Databases: REDCap & Customized Databases, Functional Genomics Consultation: Microarray Proteomics. The Biomedical Informatics Program (BMIP) provides investigators with informatics tools and methodologies to support translational researchers. Using a hybrid of collaborative and service approaches, BMIP is continually developing and deploying an array of informatics tools for bench research (bioinformatics), bedside research (clinical research informatics), and translation to practice (medical informatics). BMIP also provides a platform for collaborative and multidisciplinary informatics education and research. The Biomedical Informatics Program includes two major areas of emphasis: Translational Bioinformatics - Novel methodology development, Statistical Genetics, Functional Genomics, Clinical Research Informatics, Research Data Warehouse - Using Epic and other clinical data for research, Clinical research data management software, Epic as an interventional tool for research data management, database development, protein expression profiling, solexa sequencing, protein microarray assay, next generation sequencing is listed by: Eagle I
is related to: OHSU Oregon Clinical and Translational Research Center Core Facility
has parent organization: Oregon Health and Science University; Oregon; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156435 https://www.ohsu.edu/xd/research/centers-institutes/octri/resources/octri-research-services/designing-study.cfm SCR_009965 Oregon Clinical, BMIP, Translational Research Institute, Biomedical Informatics Program, OCTRI 2026-08-12 10:50:06 1
OHSU Bioanalytical Shared Resource Pharmacokinetics Core Facility
 
Resource Report
Resource Website
1+ mentions
OHSU Bioanalytical Shared Resource Pharmacokinetics Core Facility (RRID:SCR_009963) BSR/PKCore access service resource, core facility, service resource Core for analysis of drugs and their metabolites and bio-molecules such as simple peptides, oligonucleotides, carbohydrates, lipids, fatty acids and steroids. Provides open access to laboratory where users prepare and analyze their own samples by HPLC, GC/MS or LC/MS on equipment maintained by core personnel. Provides analysis of samples including development of analytical methods, sample preparation, and data analysis for clinical trials as well as basic science investigations. ABRF, USEDit, drugs and their metabolites analysis, HPLC, GC/MS, LC/MS is listed by: Eagle I
is related to: USEDit
has parent organization: Oregon Health and Science University; Oregon; USA
Restricted nlx_156433 http://ohsu.eagle-i.net/i/0000012a-24fd-c7a9-d994-629180000000 SCR_009963 OHSU Bioanalytical Shared Resource Pharmacokinetics Core Laboratory, OHSU Bioanalytical Shared Resource/Pharmacokinetics Core Laboratory 2026-08-12 10:50:07 5
OHSU Advanced Imaging Research Center Core Facility
 
Resource Report
Resource Website
1+ mentions
OHSU Advanced Imaging Research Center Core Facility (RRID:SCR_009960) AIRC access service resource, core facility, service resource Provides magnetic resonance instruments including Siemens 3 Tesla Prisma, Siemens Magnetom 7 Tesla, and Bruker 11.75 Tesla to support research investigating normal physiology, brain development and aging, and disease pathophysiology with high performance non invasive imaging capabilities. ABRF, USEDit, magnetic resonance imaginig, magnetic resonance instruments is listed by: Eagle I
is related to: USEDit
has parent organization: Oregon Health and Science University; Oregon; USA
Restricted nlx_156430 http://ohsu.eagle-i.net/i/00000138-2a45-30ee-9f3a-f10180000000 SCR_009960 OHSU Advanced Imaging Research Center 2026-08-12 10:50:07 2
OHSU Proteomics Shared Resource Core Facility
 
Resource Report
Resource Website
10+ mentions
OHSU Proteomics Shared Resource Core Facility (RRID:SCR_009991) access service resource, core facility, service resource Core facility that provides the following services: Protein identification and partial sequencing, Determination of whole protein mass, Targeted SRM analysis of known proteins, Protein quantitation assay, Gel electrophoresis. The OHSU Protemics Shared Resource facility was established to make state-of-the-art mass spectrometry based protein analysis analytical capabilities available to the biomedical research community at OHSU. ABRF, USEDit, partial protein sequencing, protein identification, protein mass determination by mass spectrometry, multiple reaction monitoring, protein quantitation assay, electrophoresis is listed by: Eagle I
is related to: USEDit
has parent organization: Oregon Health and Science University; Oregon; USA
nlx_156459 http://ohsu.eagle-i.net/i/0000012a-24ff-d2af-d994-629180000000 SCR_009991 OHSU Proteomics Shared Resource Core Laboratory 2026-08-12 10:50:06 12
Penn Small Animal Imaging Facility: MRI/MRS Sub-Core
 
Resource Report
Resource Website
1+ mentions
Penn Small Animal Imaging Facility: MRI/MRS Sub-Core (RRID:SCR_010032) access service resource, core facility, service resource The MR Sub-Core of the SAIF provides the instrumentation and expertise necessary to perform a broad spectrum of magnetic resonance imaging and spectroscopy studies on a wide range of biological samples including small animals (cats, rabbits, rats, mice), tissue specimens, cultured cells and tissue extracts. This facility includes a conveniently located, well equipped surgery room used for preparing the animals for MR exams and a wide assortment of supporting equipment, i.e. anesthesia machines, MR compatible vital signs monitors (SA Instruments), infusion pumps (Harvard), heating pads, etc. A variety of perishable supplies used in animal preparation are provided by the facility. is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156502 SCR_010032 2026-08-12 10:50:10 1
University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Vector Core Facility
 
Resource Report
Resource Website
10+ mentions
University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Vector Core Facility (RRID:SCR_010038) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core whose main aim is to provide vector technology for preclinical studies and other basic research applications. Its services include rovision of AAV, adenoviral and lentiviral based vectors, consultation and advice in the design of custom vectors and in vector serotype/pseudotype selection, and design, cloning and production of plasmid DNA for the production of custom vectors. vector core, vector design, vector consultation, gene therapy program is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: University of Pennsylvania; Philadelphia; USA
has parent organization: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis
is organization facet of: Penn Diabetes Research Center
is organization facet of: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis
Cystic Fibrosis NIDDK P30 DK047757 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156509 http://www.med.upenn.edu/gtp/vectorcore/ SCR_010038 University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Vector Core 2026-08-12 10:50:10 15
Penn Flow Cytometry and Cell Sorting Resource Laboratory
 
Resource Report
Resource Website
1+ mentions
Penn Flow Cytometry and Cell Sorting Resource Laboratory (RRID:SCR_010011) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 1,2023. Core facility that provides the following services: Flow cytometry analysis service, Cell sorting and analysis service, Flow cytometer analyzer access, Introductory flow cytometry training, Advanced and customized flow cytometry training, Flow cytometry consultation service, FACSAria training, Flow cytometry data analysis, BSL2+ biohazardous human cell sorting, BSL2+ murine biohazardous cell sorting, BSL2+ murine cell sorting access, Non-infectious cell sorting access. The Flow Cytometry and Cell Sorting Resource Laboratory is currently recognized as one of the largest and most comprehensive flow cytometry laboratories in the US. In 2010 it was designated a laboratory of exceptional merit by the National Cancer Institute. Using state-of-the-art technology, the resource provides a broad array of, instrumentation, support, education and consultation to the research community at the University of Pennsylvania. A wide variety of cell sorting applications are supported, from high-speed multicolor (up to 14 colors) cell sorting to low-speed, large nozzle, improved viability sorting. Additionally, a wide variety of cell analysis services (up to 20 parameters) are offered, from traditional analog, easier to use tabletop analyzers to many-laser, many-color, high-speed, fully-digital modern instrumentation. Currently the facility offers 6 cell sorters and 19 analytical instruments. A very active training and consultation program is in place to support these activities. The Scientific Director, Dr. Jonni Moore, and the Technical Director, each have over 25 years experience in the field of cytomics. Researchers at the University of Pennsylvania are increasingly engaged in research projects that require 8-plus-parameter cell sorting of infectious cells and primary human tissues. Investigators using the Flow Cytometry and Cell Sorting Shared Resource have access to virtually any type of cytometric services required for a vast array of applications. flow cytometry assay, cell separation, fluorescence activated cell sorting (facs), data analysis is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156478 SCR_010011 2026-08-12 10:50:07 3
UPR RCMI Program Shared Instrumentation Laboratories
 
Resource Report
Resource Website
1+ mentions
UPR RCMI Program Shared Instrumentation Laboratories (RRID:SCR_010132) access service resource, core facility, service resource These laboratories house large, relatively expensive research instruments, which are shared among the faculty, students and staff on campus. is listed by: Eagle I
has parent organization: University of Puerto Rico; Puerto Rico; USA
nlx_156610 SCR_010132 2026-08-12 10:50:10 4
UCC Data Management and Statistical Research Support Unit
 
Resource Report
Resource Website
1+ mentions
UCC Data Management and Statistical Research Support Unit (RRID:SCR_010074) UCC DMSRSU access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Research support, Research Training. The DMSRSU provides study design, data management, quality assurance, and statistical analysis support for UCC researchers. The DMSRSU has a strong infrastructure which includes the following subunits: Data Abstraction and Management; Data Entry; Quality Control; Data Analysis and Consultant; and Administrative and Computer Systems. Each of these subunits consists of experienced professionals readily available to assist researchers and to provide data management and statistical research support to investigators. In addition, the DMSRSU counts on a highly experienced and reliable consulting team. data management, data analysis is listed by: Eagle I
has parent organization: Central University of the Caribbean; Puerto Rico; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156546 SCR_010074 2026-08-12 10:50:11 7
Atlas of Genetics and Cytogenetics in Oncology and Haematology
 
Resource Report
Resource Website
10+ mentions
Atlas of Genetics and Cytogenetics in Oncology and Haematology (RRID:SCR_007199) data or information resource, atlas, database Online journal and database devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases. Its aim is to cover the entire field under study and it presents concise and updated reviews (cards) or longer texts (deep insights) concerning topics in cancer research and genomics. gene, cytogenetic, cancer, cancer research, genomic, online journal, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
PMID:23161685 Freely available, Available to the scientific community nif-0000-30129, biotools:atlasgeneticsoncology https://bio.tools/atlasgeneticsoncology SCR_007199 Genetics and Cytogenetics Atlas 2026-08-12 10:49:35 43
Exon Array Analyzer
 
Resource Report
Resource Website
1+ mentions
Exon Array Analyzer (RRID:SCR_008684) Exon Array Analyzer production service resource, data analysis service, analysis service resource, service resource Service that allows you to process CEL files from Affymetrix, Inc. GeneChip Exon 1.0 ST Arrays to identify alternative splicing. is listed by: OMICtools OMICS_00754 SCR_008684 2026-08-12 10:49:45 4
PROTOTYPE - Suspected Overlap Among OBO Foundry Candidate Ontologies
 
Resource Report
Resource Website
1+ mentions
PROTOTYPE - Suspected Overlap Among OBO Foundry Candidate Ontologies (RRID:SCR_008834) PROTOTYPE Suspected Overlap Among OBO Foundry Candidate Ontologies production service resource, data analysis service, analysis service resource, service resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. Service that determines the Suspected Overlap Among OBO Foundry Candidate Ontologies. has parent organization: National Center for Biomedical Ontology THIS RESOURCE IS NO LONGER IN SERVICE nlx_144632 SCR_008834 2026-08-12 10:49:48 2
Channelrhodopsin-2 enables optical activation of neurons
 
Resource Report
Resource Website
1+ mentions
Channelrhodopsin-2 enables optical activation of neurons (RRID:SCR_008833) Channelrhodopsin-2 enables optical activation of neurons production service resource, resource, material service resource, service resource Laser tool that enables neurons to be optically silenced by pulses of yellow light, the light-activated chloride pump halorhodopsin (Halo), in a paper entitled Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. Temporally precise, noninvasive control of activity in well-defined neuronal populations is a long-sought goal of systems neuroscience. We adapted for this purpose the naturally occurring algal protein Channelrhodopsin-2, a rapidly gated light-sensitive cation channel, by using lentiviral gene delivery in combination with high-speed optical switching to photostimulate mammalian neurons. We demonstrate reliable, millisecond-timescale control of neuronal spiking, as well as control of excitatory and inhibitory synaptic transmission. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. The quest to determine how precise neural activity patterns mediate computation, behavior, and pathology would be greatly aided by a set of tools for reliably activating and inactivating genetically targeted neurons, in a temporally precise and rapidly reversible fashion. Having earlier adapted a light-activated cation channel, 1channelrhodopsin-2 (ChR2), for allowing neurons to be stimulated by blue light, we searched for a complementary tool that would enable optical neuronal inhibition, driven by light of a second color. Here we report that targeting the 1codon-optimized form of the light-driven chloride pump halorhodopsin from the archaebacterium Natronomas pharaonis (hereafter abbreviated Halo) to genetically-specified neurons enables them to be silenced reliably, and reversibly, by millisecond-timescale pulses of yellow light. We show that trains of yellow and blue light pulses can drive high-fidelity sequences of hyperpolarizations and depolarizations in neurons simultaneously expressing yellow light-driven Halo and blue light-driven ChR2, allowing for the first time manipulations of neural synchrony without perturbation of other parameters such as spiking rates. The Halo/ChR2 system thus constitutes a powerful toolbox for multichannel photoinhibition and photostimulation of virally or transgenically targeted neural circuits without need for exogenous chemicals, enabling systematic analysis and engineering of the brain, and quantitative bioengineering of excitable cells. hardware, instrument, equipment has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; Anonymous donor ;
MIT Media Lab ;
Helen Hay Whitney Foundation
PMID:17375185 nlx_144630 http://channelrhodopsin.org SCR_008833 2026-08-12 10:49:52 3
Functional Neurogenesis
 
Resource Report
Resource Website
1+ mentions
Functional Neurogenesis (RRID:SCR_008830) Functional Neurogenesis data or information resource, narrative resource, blog A blog focusing on the function of adult neurogenesis in the dentate gyrus of the hippocampus, including discussion of scientific research papers, methods and protocols, and other trends or observations about the field. adult, neurogenesis, dentate gyrus, hippocampus, brain, neuron, anxiety, depressive disorder, memory, plasticity nlx_144587 SCR_008830 Functional Neurogenesis - New neurons in the adult brain. How they work and what they are good for. 2026-08-12 10:49:52 2
Genotype-IBD Sharing Test
 
Resource Report
Resource Website
100+ mentions
Genotype-IBD Sharing Test (RRID:SCR_006257) GIST resource, software application, software resource Software package to test if a marker can account in part for the linkage signal in its region. There are two versions of the software: Windows and Linux/Unix. identical by descent, genotype, gene, genetic, genomic, unix, ms-windows, linux, linkage disequilibrium, linkage, association is listed by: Genetic Analysis Software
has parent organization: Vanderbilt University; Tennessee; USA
Vanderbilt Diabetes Center ;
NHGRI HG00376;
NIDDK DK62370;
NHGRI N01-HG-15465
PMID:14872409 nlx_154133 http://phg.mc.vanderbilt.edu/content/gist SCR_006257 2026-08-12 10:49:22 120
Biobehavioral
 
Resource Report
Resource Website
10+ mentions
Biobehavioral (RRID:SCR_008710) data or information resource, narrative resource, blog THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016. Biobehavioral blog on research and medicine as a continuum from biological mechanisms to behavioural phenomena., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. THIS RESOURCE IS NO LONGER IN SERVICE nlx_11905 SCR_008710 Biobehavioral 2026-08-12 10:49:45 14

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