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Trans-NIH program encouraging and facilitating the study of the underlying mechanisms controlling blood vessel growth and development. Other aims include: to identify specific targets and to develop therapeutics against pathologic angiogenesis in order to reduce the morbidity due to abnormal blood vessel proliferation in a variety of disease states; to better understand the process of angiogenesis and vascularization to improve states of decreased vascularization; to encourage and facilitate the study of the processes of lymphangiogenesis; and to achieve these goals through a multidisciplinary approach, bringing together investigators with varied backgrounds and varied interests.
Proper citation: Trans-Institute Angiogenesis Research Program (RRID:SCR_000384) Copy
https://github.com/vlink/marge
Software package that integrates genome wide genetic variation with epigenetic data to identify collaborative transcription factor pairs. Optimized to work with chromatin accessibility assays such as ATAC-seq or DNase I hypersensitivity, as well as transcription factor binding data collected by ChIP-seq. Used to identify combinations of cell type specific transcription factors while simultaneously interpreting functional effects of non-coding genetic variation.
Proper citation: Motif Mutation Analysis for Regulatory Genomic Elements (RRID:SCR_021902) Copy
A tool for performing multi-cluster gene functional enrichment analyses on large scale data (microarray experiments with many time-points, cell-types, tissue-types, etc.). It facilitates co-analysis of multiple gene lists and yields as output a rich functional map showing the shared and list-specific functional features. The output can be visualized in tabular, heatmap or network formats using built-in options as well as third-party software. It uses the hypergeometric test to obtain functional enrichment achieved via the gene list enrichment analysis option available in ToppGene.
Proper citation: ToppCluster (RRID:SCR_001503) Copy
http://www.digestive.niddk.nih.gov
Information dissemination service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) established to increase knowledge and understanding about digestive diseases among people with these conditions and their families, health care professionals, and the general public: online, in booklets and fact sheets, by email, and over the phone. To carry out this mission, NDDIC works closely with a coordinating panel of representatives from Federal agencies, voluntary organizations on the national level, and professional groups to identify and respond to informational needs about digestive diseases. NDDIC provides the following informational products and services: * Response to inquiries about digestive diseases - ranging from information about available patient and professional education materials to statistical data. By phone (8:30 a.m. to 5 p.m. eastern time, M-F), fax, mail, and email. * Publications about specific digestive diseases, provided free of copyright, in varying reading levels. Available online or as booklets and brochures. NDDIC also sends publications to health fairs and community events. * Referrals to health professionals through the National Library of Medicine''''s MEDLINEplus includes a consumer-friendly listing of organizations that will assist you in your search for physicians and other health professionals. * Exhibits at professional meetings specific to digestive diseases, as well as cross-cutting professional meetings. NDDIC exhibits at nine professional meetings each year, including Digestive Diseases Week, American College of Gastroenterology, Society of Gastroenterology Nurses and Associates, American Academy of Family Physicians, American Academy of Physician Assistants, American Nurses Association, and the National Conference for Nurse Practitioners.
Proper citation: National Digestive Diseases Information Clearinghouse (RRID:SCR_006771) Copy
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http://iidp.coh.org/Default.aspx
The goal of the Integrated Islet Distribution Program (IIDP) is to work with the leading islet isolation centers in the U.S. to distribute high quality human islets to the diabetes research community, in order to advance scientific discoveries and translational medicine.
Proper citation: Integrated Islet Distribution Program (IIDP) (RRID:SCR_014387) Copy
http://www.diabetes-translation.org
Centers that are part of an integrated program whose cores support and enhance diabetes type II translation research. The CDTRs aim to enhance the efficiency, productivity, effectiveness and multidisciplinary nature of diabetes translation research.
Proper citation: Centers for Diabetes Translation Research (RRID:SCR_015149) Copy
http://globalprojects.ucsf.edu/project/novel-small-molecule-therapies-cystic-fibrosis
Research center that focuses on developing novel therapies for cystic fibrosis, enhancing research projects examining the mechanisms of the disease, and developing new small-molecule therapies that can be translated into the clinic.
Proper citation: Cystic Fibrosis Center - University of California San Francisco (RRID:SCR_015398) Copy
https://sites.google.com/ucsd.edu/drc/home
Research center across five institutions for clinical research in diabetes. Collaborators include UC San Diego's School of Medicine, Salk Institute, Cedars-Sinai Medical Center, UC Los Angeles' School of Medicine, and LA Biomedical Research Center.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center (RRID:SCR_015100) Copy
Research center which operates in collaboration with the University of Alabama Birmingham Comprehensive Diabetes Center to promote excellence in diabetes research and patient care. The DRC supports the areas of animal physiology, human biology and intervention and translational research. It focuses on developing new methods to treat, prevent, and ultimately cure diabetes and its complications.
Proper citation: University of Alabama at Birmingham Diabetes Research Center (RRID:SCR_015107) Copy
https://diabetes.med.umich.edu/partners/michigan-diabetes-research-center-mdrc
Multidisciplinary unit of the University of Michigan funded by the National Institute of Diabetes and Digestive and Kidney Diseases/National Institute of Health. Promotes new discoveries and enhance scientific progress through the support of basic and clinical research related to diabetes, its complications, and related disorders. Creates environment that supports innovative research; attracts and retains early stage investigators and investigators new to diabetes research; provides core services that leverage funding and unique expertise; fosters interdisciplinary collaborations; raises awareness and interest in fundamental and clinical diabetes research at their institutions, as well as locally, regionally, and nationally.
Proper citation: Michigan Diabetes Research Center (RRID:SCR_015112) Copy
Consortium of laboratory-based and clinical investigators who research etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes, and their associated microvascular and atherosclerotic complications.
Proper citation: Boston Area Diabetes Endocrinology Research Center (RRID:SCR_015072) Copy
http://www.einstein.yu.edu/centers/diabetes-research/
Research center that facilitates the research of diabetes and related studies in obesity, metabolism and endocrinology
Proper citation: Einstein-Mount Sinai Diabetes Research Center (RRID:SCR_015070) Copy
University-affiliated center that promotes research in diabetes and related metabolic and endocrine disorders at Yale University.
Proper citation: Yale Diabetes Research Center (RRID:SCR_015142) Copy
http://depts.washington.edu/diabetes/
University-affiliated center to support both basic and clinical research in diabetes and related metabolic disorders with the ultimate purpose of translating findings into opportunities to prevent these diseases and to improve clinical care and outcomes.
Proper citation: University of Washington Diabetes Research Center (RRID:SCR_015126) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/
Center whose goal is to understand the causes of both type 1 and 2 diabetes and promotes translational research that is aimed at reducing the burden of these diseases in the U.S. It has a specific focus on childhood diabetes and diabetes that affects minority populations.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center (RRID:SCR_015086) Copy
http://www.mayo.edu/research/centers-programs/center-cell-signaling-gastroenterology-c-sig
Center whose mission is to improve understanding of the signaling pathways that control the function of gastrointestinal cells in health and disease. It serves as a hub that provides access to research resources and expertise to multidisciplinary groups of basic scientists and clinical researchers.
Proper citation: Mayo Clinic Center for Cell Signaling in Gastroenterology (RRID:SCR_015224) Copy
Research center for translational research on type 2 diabetes with a strong emphasis on translation into real world health care settings and communities.
Proper citation: Georgia Center for Diabetes Translation Research (RRID:SCR_015185) Copy
http://keck.usc.edu/liver-diseases-research-center/
Center whose goal is the facilitation and fostering of interdisciplinary collaborative research in the field of pathobiology of diseases of the liver and digestive tract and the development of new treatments for these diseases.
Proper citation: USC Liver Transplant Program and Center for Liver Disease (RRID:SCR_015237) Copy
Research center that brings together research programs in human genetics and mouse models to address the causes of congenital urinary tract malformations.
Proper citation: Columbia University George M. O'Brien Urology Center (RRID:SCR_015479) Copy
http://mmpc.ucdavis.edu/index.php
Center that provides the scientific community with metabolic and physiologic phenotyping tests, services, and procedures for mouse models of diabetes, diabetic complications, obesity and related disorders in order to advance medical and biological research.
Proper citation: MMPC-University of California Davis (RRID:SCR_015357) Copy
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