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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Maq
 
Resource Report
Resource Website
50+ mentions
Maq (RRID:SCR_005485) Maq software resource A set of programs that map and assemble fixed-length Solexa/SOLiD reads in a fast and accurate way. command-line, curses/ncurses, opengl, c, c++, perl, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: SourceForge
DOI:10.1101/gr.078212.108 GNU General Public License, v2 OMICS_00668, biotools:maq https://bio.tools/maq, https://sources.debian.org/src/maq/ SCR_005485 mapass2, Mapping and Assembly with Quality, Mapping and Assembly with Qualities, Maq: Mapping and Assembly with Qualities 2026-09-12 12:56:26 74
ea-utils
 
Resource Report
Resource Website
100+ mentions
ea-utils (RRID:SCR_005553) ea-utils software resource Command-line software tools for processing biological sequencing data. Barcode demultiplexing, adapter trimming, etc. Primarily written to support an Illumina based pipeline - but should work with any FASTQs. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.2174/1875036201307010001 MIT License OMICS_01041, biotools:ea-utils https://bio.tools/ea-utils, https://sources.debian.org/src/ea-utils/ SCR_005553 ea-utils: FASTQ processing utilities 2026-09-12 12:56:28 289
MethylExtract
 
Resource Report
Resource Website
10+ mentions
MethylExtract (RRID:SCR_005446) MethylExtract software resource A user friendly software tool to generate i) high quality, whole genome methylation maps and ii) to detect sequence variation within the same sample preparation. bisulfite sequencing, methylation map, methylation, sequence variation, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Granada; Granada; Spain
Acknowledgement requested biotools:methylextract, OMICS_00605 https://bio.tools/methylextract SCR_005446 High-Quality methylation maps and SNV calling from BS-Seq experiments 2026-09-12 12:56:26 14
GobyWeb
 
Resource Report
Resource Website
1+ mentions
GobyWeb (RRID:SCR_005443) GobyWeb software resource Web application that facilitates the management and analysis of high-throughput sequencing (HTS) data. In the back-end, it uses the Goby framework, BWA, STAR, Last, GSNAP, Samtools, VCF-tools, along with a cluster of servers to provide rapid alignment and efficient analyses. GobyWeb makes it possible to analyze hundreds of samples in consistent ways without having to use command line tools. GobyWeb provides tools that streamline frequent data analyses for RNA-Seq, Methyl-Seq, RRBS, or DNA-Seq datasets and to enable teams of investigators to share reads and results of analyses. GobyWeb can be extended for new analyses by developing plugins. high-throughput sequencing, gene expression, dna methylation, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Weill Cornell Medical College; New York; USA
PMID:23936070 Acknowledgement requested, GNU Lesser General Public License, v3 OMICS_00601, biotools:gobyweb https://bio.tools/gobyweb SCR_005443 2026-09-12 12:56:26 3
Bowtie
 
Resource Report
Resource Website
10000+ mentions
Bowtie (RRID:SCR_005476) alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource Software ultrafast memory efficient tool for aligning sequencing reads. Bowtie is short read aligner. sequence, analysis, long, reference, read, alignment, gap, local, pair, end, rna, rnaseq, bio.tools is used by: deFuse
is used by: Short Read Sequence Typing for Bacterial Pathogens
is used by: TopHat
is used by: BS Seeker
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Bowtie 2
has parent organization: Johns Hopkins University; Maryland; USA
is required by: RelocaTE
Amazon Web Services in Education Research ;
NHGRI R01 HG006102;
NIGMS R01 GM083873
PMID:19261174
DOI:10.1186/gb-2009-10-3-r25
Free, Available for download, Freely available biotools:bowtie, OMICS_00653 https://github.com/BenLangmead/bowtie, https://bio.tools/bowtie, https://sources.debian.org/src/bowtie/ SCR_005476 2026-09-12 12:56:26 13799
TreQ
 
Resource Report
Resource Website
TreQ (RRID:SCR_005505) TreQ software resource A software read mapper for high-throughput DNA sequencing reads, in particular one to several hundred nucleotides in length, and for large edit distance between sequencing read and match in the reference genome. It can cope particularly well with indels for single-best hit recall of 200nt reads simulated from the human reference genome. TreQ performs best at a running time comparable to BWA at large edit distance settings. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Rutgers University; New Jersey; USA
PMID:22962448 GNU General Public License OMICS_00695, biotools:treq https://bio.tools/treq SCR_005505 TreQ: Indel-tolerant Read Mapper 2026-09-12 12:56:27 0
MicrobesOnline
 
Resource Report
Resource Website
100+ mentions
MicrobesOnline (RRID:SCR_005507) MicrobesOnline analysis service resource, data analysis service, data or information resource, database, production service resource, service resource, software resource, source code MicrobesOnline is designed specifically to facilitate comparative studies on prokaryotic genomes. It is an entry point for operon, regulons, cis-regulatory and network predictions based on comparative analysis of genomes. The portal includes over 1000 complete genomes of bacteria, archaea and fungi and thousands of expression microarrays from diverse organisms ranging from model organisms such as Escherichia coli and Saccharomyces cerevisiae to environmental microbes such as Desulfovibrio vulgaris and Shewanella oneidensis. To assist in annotating genes and in reconstructing their evolutionary history, MicrobesOnline includes a comparative genome browser based on phylogenetic trees for every gene family as well as a species tree. To identify co-regulated genes, MicrobesOnline can search for genes based on their expression profile, and provides tools for identifying regulatory motifs and seeing if they are conserved. MicrobesOnline also includes fast phylogenetic profile searches, comparative views of metabolic pathways, operon predictions, a workbench for sequence analysis and integration with RegTransBase and other microbial genome resources. The next update of MicrobesOnline will contain significant new functionality, including comparative analysis of metagenomic sequence data. Programmatic access to the database, along with source code and documentation, is available at http://microbesonline.org/programmers.html. microbe, genome, bacteria, archaea, fungi, prokaryote, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
DOE DE-AC02-05CH11231 PMID:19906701 nlx_144607, biotools:microbesonline https://bio.tools/microbesonline SCR_005507 Microbial Genomics Database, Microbes Online 2026-09-12 12:56:27 166
DiProGB
 
Resource Report
Resource Website
1+ mentions
DiProGB (RRID:SCR_005651) DiProGB software resource Genome browser that encodes the genome sequence by physico-chemical dinucleotide properties such as stacking energy, melting temperature or twist angle. Analyses can be performed for the + and ?, as well as for the double strand. genome, browser, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Dinucleotide Property Database
PMID:19605418 Free, Freely available biotools:diprogb, OMICS_00880 https://bio.tools/diprogb SCR_005651 DiProGB - The Dinucleotide Properties Genome Browser, Dinucleotide Properties Genome Browser 2026-09-12 12:56:29 4
Bambino
 
Resource Report
Resource Website
1+ mentions
Bambino (RRID:SCR_005649) Bambino analysis service resource, data analysis service, production service resource, service resource, software resource A variant detector and graphical alignment viewer for next-generation sequencing data in the SAM/BAM format, which is capable of pooling data from multiple source files. Bambino may be launched online via Java Web Start or downloaded and run locally. java, next-generation sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: National Cancer Institute
PMID:21278191 Https://cgwb.nci.nih.gov/goldenPath/bamview/documentation/Bambino_Click-thru-agreement-for-executable_final.txt OMICS_00876, biotools:bambino https://bio.tools/bambino SCR_005649 Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format 2026-09-12 12:56:29 5
BS Seeker
 
Resource Report
Resource Website
1+ mentions
BS Seeker (RRID:SCR_005641) data analysis software, data processing software, sequence analysis software, software application, software resource Software which performs accurate and fast mapping of bisulfite-treated short reads. Supplementary information and examples are provided on the site. bisulfite sequencing, sequence analysis software, short read, sequence mapping, bio.tools uses: Bowtie
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Bs-Seeker2
has parent organization: University of California at Los Angeles; California; USA
PMID:20416082 Free, Available for download, Freely available OMICS_00578, biotools:bs_seeker https://bio.tools/bs_seeker SCR_005641 Bisulfite Sequence Seeker 2026-09-12 12:56:29 3
DMRforPairs
 
Resource Report
Resource Website
1+ mentions
DMRforPairs (RRID:SCR_005702) software resource Software for identifying differentially methylated regions between unique samples using array based methylation profiles. It allows researchers to compare n greater than or equal to 2 unique samples with regard to their methylation profile. The (pairwise) comparison of n unique single samples distinguishesit from other existing pipelines as these often compare groups of samples in either single CpG locus or region based analysis. DMRforPairs defines regions of interest as genomic ranges with sufficient probes located in close proximity to each other. Probes in one region are optionally annotated to the same functional class(es). Differential methylation is evaluated by comparing the methylation values within each region between individual samples and (if the difference is sufficiently large), testing this difference formally for statistical significance. standalone software, mac os x, unix/linux, windows, r, annotation, dna methylation, differential methylation, microarray, report writing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24884391 GNU General Public License, v2 or greater biotools:dmrforpairs, OMICS_04059 https://bio.tools/dmrforpairs SCR_005702 DMR2+, DMRforPairs: identifying Differentially Methylated Regions between unique samples using array based methylation profiles 2026-09-12 12:56:30 4
Bismark
 
Resource Report
Resource Website
1000+ mentions
Bismark (RRID:SCR_005604) Bismark software resource Software tool to map bisulfite converted sequence reads and determine cytosine methylation states. Flexible aligner and methylation caller for Bisulfite-Seq applications. Used to map bisulfite treated sequencing reads to genome of interest and perform methylation calls in single step. Map bisulfite treated sequence reads, determine cytosine methylation states, genome, sequence reads, perform methylation calls, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Babraham Institute
PMID:21493656
DOI:10.1093/bioinformatics/btr167
Free, Available for download, Freely available biotools:bismark, OMICS_00575 https://github.com/FelixKrueger/Bismark, https://bio.tools/bismark https://sources.debian.org/src/bismark/ SCR_005604 2026-09-12 12:56:28 1200
ToppGene Suite
 
Resource Report
Resource Website
1000+ mentions
ToppGene Suite (RRID:SCR_005726) analysis service resource, data analysis service, data or information resource, database, portal, production service resource, resource, service resource ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. ToppGene Suite is a one-stop portal for (i) gene list functional enrichment, (ii) candidate gene prioritization using either functional annotations or network analysis and (iii) identification and prioritization of novel disease candidate genes in the interactome. Functional annotation-based disease candidate gene prioritization uses a fuzzy-based similarity measure to compute the similarity between any two genes based on semantic annotations. The similarity scores from individual features are combined into an overall score using statistical meta-analysis. gene portal, enrichment analysis, functional annotation, gene prioritization, protein interaction, bio.tools, FASEB list is listed by: Gene Ontology Tools
is listed by: NIDDK Information Network (dkNET)
is listed by: GUDMAP Ontology
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: ToppCluster
State of Ohio Computational Medicine Center ODD TECH 04-042;
NIDDK 1U01DK70219;
NIDDK P30DK078392
PMID:19465376 Free for academic use nlx_149183, biotools:toppgene_suite https://bio.tools/toppgene_suite SCR_005726 ToppGene 2026-09-12 12:56:30 1131
TMAJ
 
Resource Report
Resource Website
10+ mentions
TMAJ (RRID:SCR_005601) TMAJ software resource Open-source software to support information and images related to tissue micro-arrays. It contains support for multiple organ systems, multiple users, image analysis, and is designed to be compliant with HIPPA regulations. Patients, specimens, blocks, slides, cores, images, and scores can all be stored and viewed. Features include advanced security, custom dynamic fields, and an image analysis program. tissue microarray, java, java swing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Johns Hopkins University; Maryland; USA
has parent organization: SourceForge
GNU General Public License, v3 biotools:tmaj, OMICS_00823 https://bio.tools/tmaj SCR_005601 TMAJ Software Project 2026-09-12 12:56:28 10
GoFish
 
Resource Report
Resource Website
1+ mentions
GoFish (RRID:SCR_005682) GoFish analysis service resource, data analysis service, production service resource, service resource, software resource, source code Software program, available as a Java applet online or to download, allows the user to select a subset of Gene Ontology (GO) attributes, and ranks genes according to the probability of having all those attributes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, ontology or annotation browser, java, windows, mac os x, linux, unix, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
has parent organization: Harvard Medical School; Massachusetts; USA
Aventis Pharmaceuticals ;
Howard Hughes Medical Institute ;
NHGRI
PMID:12691998 THIS RESOURCE IS NO LONGER IN SERVICE biotools:gofish, nlx_149126, OMICS_02272 http://llama.mshri.on.ca/Software.html, https://bio.tools/gofish SCR_005682 2026-09-12 12:56:29 1
Maqview
 
Resource Report
Resource Website
Maqview (RRID:SCR_005632) MaqView data processing software, data visualization software, software application, software resource A graphical read alignment viewer specifically designed for the Maq alignment file and allows you to see the mismatches, base qualities and mapping qualities. It is highly efficient in speed, memory and disk usage. Maqview is based on OpenGL and is known to work on both Mac OS X and Linux. Porting to Windows is in principle easy. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
DOI:10.1101/gr.078212.108 GNU General Public License OMICS_00889, biotools:maqview https://bio.tools/maqview, https://sources.debian.org/src/maqview/ SCR_005632 Mapping and Assembly with Qualities Viewer, M.A.Q Viewer 2026-09-12 12:56:29 0
Staden Package
 
Resource Report
Resource Website
50+ mentions
Staden Package (RRID:SCR_005629) software resource A fully developed set of DNA sequence assembly (Gap4 and Gap5), editing and analysis tools (Spin) for Unix, Linux, MacOSX and MS Windows. c, unix/linux, sequence assembly, dna/protein analysis, spin, sequence alignment, genome, genome viewer, c++, fortran, tcl, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:20513662
DOI:10.1093/bioinformatics/btq268
BSD License OMICS_00894, biotools:staden https://bio.tools/staden, https://sources.debian.org/src/staden/ SCR_005629 Staden Package 2026-09-12 12:56:29 87
FunCluster
 
Resource Report
Resource Website
1+ mentions
FunCluster (RRID:SCR_005774) FunCluster data analysis software, data processing software, software application, software resource FunCluster is a genomic data analysis algorithm which performs functional analysis of gene expression data obtained from cDNA microarray experiments. Besides automated functional annotation of gene expression data, FunCluster functional analysis aims to detect co-regulated biological processes through a specially designed clustering procedure involving biological annotations and gene expression data. FunCluster''''s functional analysis relies on Gene Ontology and KEGG annotations and is currently available for three organisms: Homo Sapiens, Mus Musculus and Saccharomyces Cerevisiae. FunCluster is provided as a standalone R package, which can be run on any operating system for which an R environment implementation is available (Windows, Mac OS, various flavors of Linux and Unix). Download it from the FunCluster website, or from the worldwide mirrors of CRAN. FunCluster is provided freely under the GNU General Public License 2.0. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible genomic, gene, functional analysis, gene expression, cdna microarray, cdna, microarray, function, cluster, annotation, biological process, statistical analysis, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: Cordelier Research Center
PMID:17007070
PMID:16506959
PMID:16046292
Free for academic use, GNU General Public License, v2 nlx_149242, biotools:funcluster https://bio.tools/funcluster SCR_005774 FunCluster R Package, FunCluster Algorithm 2026-09-12 12:56:31 2
InterProScan
 
Resource Report
Resource Website
5000+ mentions
InterProScan (RRID:SCR_005829) analysis service resource, data access protocol, data analysis service, data analysis software, data processing software, production service resource, service resource, software application, software resource, web service Software package for functional analysis of sequences by classifying them into families and predicting presence of domains and sites. Scans sequences against InterPro's signatures. Characterizes nucleotide or protein function by matching it with models from several different databases. Used in large scale analysis of whole proteomes, genomes and metagenomes. Available as Web based version and standalone Perl version and SOAP Web Service. functional, analysis, sequence, protein, nucleotide, predict, presence, domain, site, proteome, genome, metagenome, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Gene Ontology
is related to: RARTF
is related to: InterPro
is related to: LegumeIP
is related to: UniProtKB
has parent organization: European Bioinformatics Institute
Biotechnology and Biological Sciences Research Council ;
EMBL ;
European Union
PMID:15980438
PMID:17202162
PMID:24451626
Free, Available for download, Freely available OMICS_01479, biotools:interproscan_4, nlx_149337 https://www.ebi.ac.uk/interpro/download.html, https://bio.tools/interproscan_4 SCR_005829 InterProScan Sequence Search, InterProScan 2, InterProScan 3, InterProScan 4, InterProScan 5 2026-09-12 12:56:32 7512
ccPDB - Compilation and Creation of datasets from PDB
 
Resource Report
Resource Website
1+ mentions
ccPDB - Compilation and Creation of datasets from PDB (RRID:SCR_005870) ccPDB data access protocol, data or information resource, database, software resource, web service ccPDB (Compilation and Creation of datasets from PDB) is designed to provide service to scientific community working in the field of function or structure annoation of proteins. This database of datasets is based on Protein Data Bank (PDB), where all datasets were derived from PDB. ccPDB have four modules; i) compilation of datasets, ii) creation of datasets, iii) web services and iv) Important links. * Compilation of Datasets: Datasets at ccPDB can be classified in two categories, i) datasets collected from literature and ii) datasets compiled from PDB. We are in process of collecting PDB datasetsfrom literature and maintaining at ccPDB. We are also requesting community to suggest datasets. In addition, we generate datasets from PDB, these datasets were generated using commonly used standard protocols like non-redundant chains, structures solved at high resolution. * Creation of datasets: This module developed for creating customized datasets where user can create a dataset using his/her conditions from PDB. This module will be useful for those users who wish to create a new dataset as per ones requirement. This module have six steps, which are described in help page. * Web Services: We integrated following web services in ccPDB; i) Analyze of PDB ID service allows user to submit their PDB on around 40 servers from single point, ii) BLAST search allows user to perform BLAST search of their protein against PDB, iii) Structural information service is designed for annotating a protein structure from PDB ID, iv) Search in PDB facilitate user in searching structures in PDB, v)Generate patterns service facility to generate different types of patterns required for machine learning techniques and vi) Download useful information allows user to download various types of information for a given set of proteins (PDB IDs). * Important Links: One of major objectives of this web site is to provide links to web servers related to functional annotation of proteins. In first phase we have collected and compiled these links in different categories. In future attempt will be made to collect as many links as possible. secondary structure, nucleic acid interaction, ligand interaction, structure, nucleic acid, interaction, ligand, data set, function, protein, annotate, tight-turn, nucleotide interacting residue, metals interacting residue, dna/rna binding residue, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Institute of Microbial Technology; Chandigarh; India
OSDD ;
DBT ;
Council of Scientific and Industrial Research; New Delhi; India
PMID:22139939 biotools:ccpdb, nlx_149416 https://bio.tools/ccpdb SCR_005870 Compilation and Creation of datasets from PDB, ccPDB - Compilation Creation of datasets from PDB 2026-09-12 12:56:32 2

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