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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
beadarray
 
Resource Report
Resource Website
100+ mentions
beadarray (RRID:SCR_001314) beadarray software resource Software package to read bead-level data (raw TIFFs and text files) output by BeadScan as well as bead-summary data from BeadStudio. Methods for quality assessment and low-level analysis are provided. microarray, quality control, one channel, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: Bioconductor
PMID:17586828 GNU General Public License, v2 OMICS_02021, biotools:beadarray https://bio.tools/beadarray SCR_001314 beadarray - Quality assessment and low-level analysis for Illumina BeadArray data 2025-04-09 11:47:02 116
MACAT
 
Resource Report
Resource Website
MACAT (RRID:SCR_001350) MACAT software resource Software library that contains functions to investigate links between differential gene expression and the chromosomal localization of the genes. It is motivated by the common observation of phenomena involving large chromosomal regions in tumor cells. MACAT is the implementation of a statistical approach for identifying significantly differentially expressed chromosome regions. differential expression, microarray, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:15572464 Artistic License, v2 OMICS_01989, biotools:macat https://bio.tools/macat SCR_001350 MicroArray Chromosome Analysis Tool 2025-04-09 11:47:05 0
lapmix
 
Resource Report
Resource Website
lapmix (RRID:SCR_001347) lapmix software resource Software to identify differentially expressed genes. A hierarchical Bayesian approach is used, and the hyperparameters are estimated using empirical Bayes. differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or newer biotools:lapmix, OMICS_01992 https://bio.tools/lapmix SCR_001347 Laplace Mixture Model in Microarray Experiments 2025-04-09 11:47:05 0
FARMS
 
Resource Report
Resource Website
10+ mentions
FARMS (RRID:SCR_001344) FARMS software resource Software using a model-based technique for summarizing high-density oligonucleotide array data at probe level for Affymetrix GeneChips. It is based on a factor analysis model for which a Bayesian maximum a posteriori method optimizes the model parameters under the assumption of Gaussian measurement noise. oligonucleotide array, probe, affymetrix genechip, r, unix, windows, microarray, summarization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Johannes Kepler University of Linz; Linz; Austria
PMID:16473874 Acknowledgement requested OMICS_01995, biotools:farms https://bio.tools/farms SCR_001344 Factor Analysis for Robust Microarray Summarization 2025-04-09 11:47:04 28
bridge
 
Resource Report
Resource Website
100+ mentions
bridge (RRID:SCR_001343) bridge software resource Software package to test for differentially expressed genes with microarray data. It can be used with both cDNA microarrays or Affymetrix chip. The packge fits a robust Bayesian hierarchical model for testing for differential expression. Outliers are modeled explicitly using a $t$-distribution. The model includes an exchangeable prior for the variances which allow different variances for the genes but still shrink extreme empirical variances. The model can be used for testing for differentially expressed genes among multiple samples, and can distinguish between the different possible patterns of differential expression when there are three or more samples. Parameter estimation is carried out using a novel version of Markov Chain Monte Carlo that is appropriate when the model puts mass on subspaces of the full parameter space. cdna microarray, affymetrix chip, differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:16542223 GNU General Public License, v2 or newer OMICS_01996, biotools:bridge https://bio.tools/bridge SCR_001343 Bayesian Robust Inference for Differential Gene Expression 2025-04-09 11:47:04 136
aroma.light
 
Resource Report
Resource Website
1+ mentions
aroma.light (RRID:SCR_001312) aroma.light software resource Light-weight software package for normalization and visualization of microarray data using only basic R data types. Software can be used standalone, be utilized in other packages, or be wrapped up in higher-level classes. infrastructure, microarray, preprocessing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
DOI:10.1186/1471-2105-11-245 Free, Available for download, Freely available OMICS_01998, biotools:aroma.light https://bio.tools/aroma.light
https://sources.debian.org/src/r-bioc-aroma.light/
SCR_001312 2025-04-09 11:47:02 1
BeadDataPackR
 
Resource Report
Resource Website
BeadDataPackR (RRID:SCR_001310) BeadDataPackR software resource Software that provides functionality for the compression and decompression of raw bead-level data from the Illumina BeadArray platform. microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:20981138 GNU General Public License, v2 biotools:beaddatapackr, OMICS_02023 https://bio.tools/beaddatapackr SCR_001310 BeadDataPackR - Compression of Illumina BeadArray data 2025-04-09 11:47:02 0
OLIN
 
Resource Report
Resource Website
10+ mentions
OLIN (RRID:SCR_001304) OLIN software resource Software functions for normalization of two-color microarrays by optimised local regression and for detection of artifacts in microarray data. r, normalization, visualization, quality control, two-channel, microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Humboldt University of Berlin; Berlin; Germany
has parent organization: Bioconductor
PMID:15585527 GNU General Public License, v2 biotools:olin, OMICS_02029 https://bio.tools/olin SCR_001304 Optimised Local Intensity-dependent Normalisation 2025-04-09 11:47:01 17
qcmetrics
 
Resource Report
Resource Website
1+ mentions
qcmetrics (RRID:SCR_001303) qcmetrics software resource Software package that provides a framework for generic quality control of data. It permits to create, manage and visualise individual or sets of quality control metrics and generate quality control reports in various formats. mass spectrometry, microarray, proteomics, quality control, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 OMICS_02032, biotools:qcmetrics, BioTools:qcmetrics https://bio.tools/qcmetrics
https://bio.tools/qcmetrics
https://bio.tools/qcmetrics
SCR_001303 qcmetrics - A Framework for Quality Control 2025-04-09 11:47:01 1
DEXUS
 
Resource Report
Resource Website
1+ mentions
DEXUS (RRID:SCR_001309) DEXUS software resource Software package that identifies differentially expressed genes in RNA-Seq data under all possible study designs such as studies without replicates, without sample groups, and with unknown conditions. It works also for known conditions, for example for RNA-Seq data with two or multiple conditions. RNA-Seq read count data can be provided both by the S4 class Count Data Set and by read count matrices. Differentially expressed transcripts can be visualized by heatmaps, in which unknown conditions, replicates, and samples groups are also indicated. This software is fast since the core algorithm is written in C. For very large data sets, a parallel version of DEXUS is provided in this package. DEXUS is a statistical model that is selected in a Bayesian framework by an EM algorithm. It does not need replicates to detect differentially expressed transcripts, since the replicates (or conditions) are estimated by the EM method for each transcript. The method provides an informative/non-informative value to extract differentially expressed transcripts at a desired significance level or power. classification, differential expression, gene expression, hapmap, quality control, rna-seq, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24049071 GNU Lesser General Public License, v2 or newer biotools:dexus, OMICS_02024 https://bio.tools/dexus SCR_001309 DEXUS - Identifying Differential Expression in RNA-Seq Studies with Unknown Conditions or without Replicates 2025-04-09 11:47:02 1
CisGenome
 
Resource Report
Resource Website
50+ mentions
CisGenome (RRID:SCR_001558) data analysis tool Integrated software tool for tiling array, ChIP-seq, genome and cis-regulatory element analysis. sequencing software, chip seq, downstream analysis, chip analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
works with: TileMap
PMID:18978777 Free, Non-commercial use OMICS_00423, biotools:cisgenome https://bio.tools/cisgenome http://biogibbs.stanford.edu/~jihk/CisGenome/index.htm SCR_001558 CisGenome v2.0 2025-04-09 11:47:23 80
vsn
 
Resource Report
Resource Website
1+ mentions
vsn (RRID:SCR_001459) vsn software resource Software package that implements a method for normalizing microarray intensities, both between colours within array, and between arrays. The method uses a robust variant of the maximum-likelihood estimator for the stochastic model of microarray data described in the references. The model incorporates data calibration (a.k.a. normalization), a model for the dependence of the variance on the mean intensity, and a variance stabilizing data transformation. Differences between transformed intensities are analogous to normalized log-ratios. However, in contrast to the latter, their variance is independent of the mean, and they are usually more sensitive and specific in detecting differential transcription. microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
Artistic License, v2 OMICS_01977, biotools:vsn https://bio.tools/vsn SCR_001459 vsn - Variance stabilization and calibration for microarray data 2025-04-09 11:47:14 3
PerM
 
Resource Report
Resource Website
50+ mentions
PerM (RRID:SCR_004223) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package to perform highly efficient genome scale alignments for hundreds of millions of short reads produced by the ABI SOLiD and Illumina sequencing platforms. It capable of providing full sensitivity for alignments within 4 mismatches for 50bp SOLID reads and 9 mismatches for 100bp Illumina reads.Efficient mapping of short sequencing reads with periodic full sensitive spaced seeds. Short sequencing mapping, short sequencing read, next-generation sequencing, genome, alignment, short read, abi, solid, illumina, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Clippers
has parent organization: Google Code
has parent organization: University of Southern California; Los Angeles; USA
PMID:19675096
DOI:10.1093/bioinformatics/btp486
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00675, biotools:perm https://bio.tools/perm
https://sources.debian.org/src/perm/
SCR_004223 PERiodic seed Mapping, Periodic seed Mapping 2025-04-09 11:51:36 59
MMAPPR
 
Resource Report
Resource Website
1+ mentions
MMAPPR (RRID:SCR_005092) MMAPPR software resource A software analysis pipeline for mapping mutations using RNA-seq that works without parental strain information, without the requirement of a pre-existing snp map of the organism, and without erroneous assumptions that recombination occurs at the same frequency across the genome. In addition, it compensates for the considerable amount of noise in RNA-seq datasets and simultaneously identifies the region where the mutation lies and generates a list of putative coding region mutations in the linked genomic segment. MMAPPR can utilize RNA-seq datasets from isolated tissues or whole organisms that are often generated for phenotypic analysis and gene network analysis in novel mutants. mutation, rna-seq, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Utah; Utah; USA
PMID:23299975 Acknowledgement requested OMICS_01361, biotools:mmappr https://bio.tools/mmappr SCR_005092 Mutation Mapping Analysis Pipeline for Pooled RNA-seq 2025-04-09 11:52:27 7
SLIQ
 
Resource Report
Resource Website
1+ mentions
SLIQ (RRID:SCR_005003) SLIQ software resource Software for simple linear inequalities based Mate-Pair reads filtering and scaffolding. A set of simple linear inequalities (SLIQ) derived from the geometry of contigs on the line that can be used to predict the relative positions and orientations of contigs from individual mate pair reads and thus produce a contig digraph. The SLIQ inequalities can also filter out unreliable mate pairs and can be used as a pre-processing step for any scaffolding algorithm. This tool filters mate pairs and then produces a Directed Contig Graph (contig diGraph). Also provided is a Naive scaffolder that can then produce scaffolds out of the contig diGraph. python, scaffolding, contig position, contig orientation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:23057825 biotools:sliq, OMICS_00048 https://bio.tools/sliq SCR_005003 Simple linear inequalities, SLiQ: Simple linear inequalities based Mate-Pair reads filtering and scaffolding 2025-04-09 11:52:21 3
SOPRA
 
Resource Report
Resource Website
10+ mentions
SOPRA (RRID:SCR_005035) SOPRA software resource Software tool to exploit the mate pair/paired-end information for assembly of short reads from high throughput sequencing platforms, e.g. Illumina and SOLiD. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:20576136 Acknowledgement requested biotools:sopra, OMICS_00049 https://bio.tools/sopra SCR_005035 SOPRA - Statistical Optimization of Paired Read Assembly, Statistical Optimization of Paired Read Assembly 2025-04-09 11:52:23 19
SSPACE
 
Resource Report
Resource Website
100+ mentions
SSPACE (RRID:SCR_005056) SSPACE software resource A stand-alone software program for scaffolding pre-assembled contigs using paired-read data. Main features are: a short runtime, multiple library input of paired-end and/or mate pair datasets and possible contig extension with unmapped sequence reads. scaffolding, contig, genome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21149342
DOI:10.1093/bioinformatics/btq683
GNU General Public License, Registration required biotools:sspace, OMICS_00050 https://bio.tools/sspace
https://sources.debian.org/src/sspace/
SCR_005056 2025-04-09 11:52:25 410
MBCluster.Seq
 
Resource Report
Resource Website
1+ mentions
MBCluster.Seq (RRID:SCR_005079) MBCluster.Seq software resource Software to cluster genes based on Poisson or Negative-Binomial model for RNA-Seq or other digital gene expression (DGE) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24191069 GNU General Public License, >/=v3 OMICS_01417, biotools:mbcluster.seq https://bio.tools/mbcluster.seq SCR_005079 MBCluster.Seq: Model-Based Clustering for RNA-seq Data 2025-04-09 11:52:26 1
GRASS
 
Resource Report
Resource Website
50+ mentions
GRASS (RRID:SCR_005071) GRASS software resource A generic algorithm for scaffolding next-generation sequencing assemblies. next-generation sequencing, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22492642 GNU General Public License, v3 biotools:GRASS, OMICS_00043 https://bio.tools/GRASS SCR_005071 GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies, GeneRic ASembly Scaffolder 2025-04-09 11:52:25 73
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/
https://bio.tools/g-blastn
SCR_005062 2025-04-09 11:52:25 0

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