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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Cdbfasta
 
Resource Report
Resource Website
Cdbfasta (RRID:SCR_016057) CDB data compression software, data processing software, data transfer software, software application, software resource, software toolkit Software tool for indexing and retrieval of nucleotide sequences from FASTA (DNA and protein sequence alignment software) record databases. It has the option to compress data records. index, retrieval, nucleotide, sequence, fasta, database, multi file, compress, record is listed by: Debian
is listed by: OMICtools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
has parent organization: University of Pittsburgh; Pennsylvania; USA
The Free Software Foundation (FSF) Free, Available for download OMICS_19793 https://github.com/gpertea/cdbfasta, https://sources.debian.org/src/cdbfasta/ SCR_016057 Constant DataBase 2026-08-29 11:25:11 0
Clonalframe
 
Resource Report
Resource Website
100+ mentions
Clonalframe (RRID:SCR_016060) data analysis software, data processing software, sequence analysis software, software application, software resource Software package for the inference of bacterial microevolution using multilocus sequence data. It is used to identify the clonal relationships between the members of a sample, while also estimating the chromosomal position of homologous recombination events that have disrupted the clonal inheritance. analysis, sequence, inference, bacteria, microevolution, multilocus, clonal, sample, chromosome, homologuous, recombination, disrupted, inheritance, DNA, genome is listed by: Debian
is listed by: OMICtools
is related to: Imperial College London; London; United Kingdom
is related to: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust DOI:10.1534/genetics.106.063305 Free, Available for download OMICS_14623 https://github.com/xavierdidelot/ClonalFrameML, https://sources.debian.org/src/clonalframe/ SCR_016060 ClonalFrameML 2026-08-29 11:25:11 407
Daligner
 
Resource Report
Resource Website
10+ mentions
Daligner (RRID:SCR_016066) alignment software, data processing software, image analysis software, software application, software resource, software toolkit Software alignment tool to find all significant local alignments between long and noisy, up to 15% on average reads encoded in a Dazzler database. Used for DNA sequence assembly, specifically for next generation long-read sequencers such as the Pacbio RS II and Sequel sequencers. alignment, read, encode, dazzler, database, DNA, sequence, assembly, next, generation uses: Dazzler
is listed by: Debian
has parent organization: Max Planck Institute of Molecular Cell Biology and Genetics; Dresden; Germany
DOI:10.1007/978-3-662-44753-6_5 Free, Available for download https://sources.debian.org/src/daligner/ SCR_016066 2026-08-29 11:25:29 18
HyPhy
 
Resource Report
Resource Website
1000+ mentions
HyPhy (RRID:SCR_016162) data analysis software, data processing software, sequence analysis software, software application, software resource, software toolkit Open source software package for comparative sequence analysis using stochastic evolutionary models. Used for analysis of genetic sequence data in particular the inference of natural selection using techniques in phylogenetics, molecular evolution, and machine learning. analysis, genetic, sequence, multiply, alignment, rate, pattern, data, evolution, platform, python, r, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NIGMS R01 ;
NIH R01 AI47745;
NIH U01 AI43638;
NSF DBI-0096033;
NSF DEB-9996118;
University of California Universitywide AIDS Research Program IS02-SD-701;
University of California ;
San Diego Center for AIDS Research/NIAID Developmental Award 2 P30 AI36214
PMID:15509596 Free, Available for download, Freely available SCR_016271, biotools:HyPhy, OMICS_04235 https://sources.debian.org/src/hyphy-pt/, https://veg.github.io/hyphy-site/, https://github.com/veg/hyphy, https://bio.tools/HyPhy, SCR_016162 HyPhy:Hypothesis Testing using Phylogenies, Hyphy-pt 2026-08-29 11:25:14 1586
Indelible
 
Resource Report
Resource Website
10+ mentions
Indelible (RRID:SCR_016163) simulation software, software application, software resource Software that generates nucleotide, amino acid and codon sequence data by simulating insertions and deletions (indels) as well as substitutions. It is used for biological sequence simulation of multi-partitioned nucleotide, amino-acid, or codon data sets through the processes of insertion, deletion, and substitution in continuous time. indel, insertion, deletion, biological, sequence, simulation, multi-partitioned, nucleotide, amio-acid, codon, data, set, insertion, deletion, substitution, continous, time, non-homogeneous, non-stationary, phylogeny, simulator, evolution is listed by: Debian
is listed by: OMICtools
BBSRC ;
EPSRC/MRC Doctoral Training Centre studentship
PMID:19423664 Free, Available for download OMICS_15369 https://sources.debian.org/src/indelible/ SCR_016163 2026-08-29 11:25:33 24
Fastml
 
Resource Report
Resource Website
100+ mentions
Fastml (RRID:SCR_016092) data access protocol, software resource, web application, web service Web application for the reconstruction of ancestral sequences. It computes maximum likelihood ancestral sequence reconstruction based on the phylogenetic relations between homologous sequences. ancestral, amino-acid, sequence, reconstruction, phylogenetic, relation, accurate, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Bioinformatics Center at Tel-Aviv University ;
Israel Science Foundation 878/09
PMID:22661579 Free, Freely available biotools:fastml, OMICS_08650 https://bio.tools/fastml, https://sources.debian.org/src/fastml/ SCR_016092 The FastML Server 2026-08-29 11:25:06 111
Gubbins
 
Resource Report
Resource Website
500+ mentions
Gubbins (RRID:SCR_016131) data analysis software, data processing software, sequence analysis software, software application, software resource Software application as an algorithm that iteratively identifies loci containing elevated densities of base substitutions while concurrently constructing a phylogeny based on the putative point mutations outside of these regions. It is used for phylogenetic analysis of genome sequences and generating highly accurate reconstructions under realistic models of short-term bacterial evolution., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. rapid, phylogenetic, analysis, large, sample, recombinant, bacteria, whole, genome, sequence, loci, elevated, densities, base, substitiution, mutatiion, outside, region, evolution, alignment is listed by: Debian
is listed by: OMICtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust 098051 PMID:25414349 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_14386 https://sources.debian.org/src/gubbins/ SCR_016131 Gubbins: Genealogies Unbiased By recomBinations In Nucleotide Sequences 2026-08-29 11:25:13 604
Garlic
 
Resource Report
Resource Website
10+ mentions
Garlic (RRID:SCR_016118) data analysis software, data processing software, data visualization software, sequence analysis software, software application, software resource Software application for visualization and editing of biomolecules. Used for the investigation of membrane proteins, visualization of other proteins and geometric objects, and analysis of protein sequences. visualization, editing, biomolecule, investigation, membrane, protein, analyze, sequence is listed by: Debian
is listed by: OMICtools
Open source, Free, Available for download OMICS_21303 https://sources.debian.org/src/garlic/ SCR_016118 2026-08-29 11:25:07 38
LR Gapcloser
 
Resource Report
Resource Website
50+ mentions
LR Gapcloser (RRID:SCR_016194) alignment software, data processing software, image analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 18th, 2023. Software that uses long reads to close gaps in the assemblies. long, short, read, alignment, assembly, gap, closer, sequence, gene PMID:30576505 THIS RESOURCE IS NO LONGER IN SERVICE SCR_017021 SCR_016194 LR_Gapcloser 2026-08-29 11:25:08 71
Dotter
 
Resource Report
Resource Website
50+ mentions
Dotter (RRID:SCR_016080) alignment software, data analysis software, data processing software, data visualization software, image analysis software, sequence analysis software, software application, software resource Software for sequence alignment that is a graphical dot-matrix program for detailed comparison of two sequences. sequence, alignment, graphical, dot-matrix, program, comparison, two, detail is related to: SEQtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
NHGRI U54 HG00455;
Wellcome Trust Grant 098051
PMID:26801397 Free, Available for download SCR_016080 Seqtools Dotter 2026-08-29 11:25:06 84
Gff2aplot
 
Resource Report
Resource Website
Gff2aplot (RRID:SCR_016128) data processing software, data visualization software, software application, software resource Software application to visualize the alignment of two genomic sequences together with their annotations. Used to generate print-quality images for comparative genome sequence analysis. alignment, pair-wise, plot, genomic, sequence, visualize, together, annotate, analysis, parameter, dataset, is listed by: Debian
is listed by: OMICtools
PMID:14668236 Free, Available for download OMICS_19949 https://sources.debian.org/src/gff2aplot/ SCR_016128 2026-08-29 11:25:13 0
Gentle
 
Resource Report
Resource Website
1+ mentions
Gentle (RRID:SCR_016127) data analysis software, data processing software, sequence analysis software, software application, software resource, software toolkit Software for DNA and amino acid editing, database management, plasmid maps, It can also be used for restriction and ligation, alignments, sequencer data import, calculators, gel image display, PCR, and more. editing, database, management, plasmid maps, restriction, ligation, alignments, sequence, data, import, calculator, gel, image, display, PCR, cloning, genetic is listed by: Debian
is listed by: OMICtools
has parent organization: University of Cologne; Cologne; Germany
Free Software Foundation Free, Available for download OMICS_18307 https://sources.debian.org/src/gentle/ SCR_016127 GENtle 2026-08-29 11:25:07 6
Exonerate
 
Resource Report
Resource Website
100+ mentions
Exonerate (RRID:SCR_016088) alignment software, data processing software, image analysis software, software application, software resource, software toolkit Software package for sequence alignment of pairwise sequence comparison. Exonerate can be used to align sequences using many alignment models, exhaustive dynamic programming, or a variety of heuristics., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence, alignment, pairwise, comparison, dynamic, programming, heuristic, bio.tools is used by: ExonerateTransferAnnotation
is listed by: Debian
is listed by: bio.tools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:15713233 THIS RESOURCE IS NO LONGER IN SERVICE biotools:exonerate https://bio.tools/exonerate SCR_016088 2026-08-29 11:25:12 376
HUMAnN2
 
Resource Report
Resource Website
50+ mentions
HUMAnN2 (RRID:SCR_016280) HUMAnN2 data analysis software, data processing software, sequence analysis software, software application, software resource Software for profiling the presence/absence and abundance of microbial pathways in a community from metagenomic or metatranscriptomic sequencing data Used for millions of short DNA/RNA reads. This process, referred to as functional profiling, aims to describe the metabolic potential of a microbial community and its members. microbe, matagenome, metatranscription, sequence, short, read, dna, rna, metabolism Free, Available for download, Tutorial available, Acknowledgement requested SCR_016280 The HMP Unified Metabolic Analysis Network 2 2026-08-29 11:25:37 82
TraCeR
 
Resource Report
Resource Website
10+ mentions
TraCeR (RRID:SCR_016338) data analysis software, data processing software, simulation software, software application, software resource, software toolkit Software application for recovery of T cell receptor (TCR) data from single cell data. Used to reconstruct full-length, paired T cell receptor (TCR) sequences from T lymphocyte single-cell RNA sequence data. Links T cell specificity with functional response by revealing clonal relationships between cells alongside their transcriptional profiles. recovery, receptor, single, cell, data, computation, method, reconstruct, sequence, T lymphocyte, RNA, sequence is related to: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
is related to: European Bioinformatics Institute
European Research Council ;
the Lister Institute for Preventative Medicine (S.A.T.)
PMID:26950746 Free, Available for download, Freely available SCR_016338 2026-08-29 11:25:39 14
GASVPro
 
Resource Report
Resource Website
1+ mentions
GASVPro (RRID:SCR_005259) GASVPro data analysis software, data processing software, sequence analysis software, software application, software resource Software tool combining both paired read and read depth signals into probabilistic model which can analyze multiple alignments of reads. Used to find structural variation in both normal and cancer genomes using data from variety of next-generation sequencing platforms. Used to predict structural variants directly from aligned reads in SAM/BAM format.Combines read depth information along with discordant paired read mappings into single probabilistic model two common signals of structural variation. When multiple alignments of read are given, GASVPro utilizes Markov Chain Monte Carlo procedure to sample over the space of possible alignments. structural variation, genome, genomics, alignment, sequencing, variant, variation, detection, dna, paired, end, read, sequence is listed by: OMICtools
is related to: GASV
has parent organization: Brown University; Rhode Island; USA
Burroughs Wellcome Career Award at the Scientific Interface ;
NHGRI R01 HG5690
PMID:22452995 Free, Available for download, Freely available OMICS_00317 http://code.google.com/p/gasv/downloads/list SCR_005259 GASVPro: Geometric Analysis of Structural Variants 2026-08-29 11:22:18 8
BioExtract
 
Resource Report
Resource Website
10+ mentions
BioExtract (RRID:SCR_005397) BioExtract service resource An open, web-based system designed to aid researchers in the analysis of genomic data by providing a platform for the creation of bioinformatic workflows. Scientific workflows are created within the system by recording tasks performed by the user. These tasks may include querying multiple, distributed data sources, saving query results as searchable data extracts, and executing local and web-accessible analytic tools. The series of recorded tasks can then be saved as a reproducible, sharable workflow available for subsequent execution with the original or modified inputs and parameter settings. Integrated data resources include interfaces to the National Center for Biotechnology Information (NCBI) nucleotide and protein databases, the European Molecular Biology Laboratory (EMBL-Bank) non-redundant nucleotide database, the Universal Protein Resource (UniProt), and the UniProt Reference Clusters (UniRef) database. The system offers access to numerous preinstalled, curated analytic tools and also provides researchers with the option of selecting computational tools from a large list of web services including the European Molecular Biology Open Software Suite (EMBOSS), BioMoby, and the Kyoto Encyclopedia of Genes and Genomes (KEGG). The system further allows users to integrate local command line tools residing on their own computers through a client-side Java applet. nucleotide sequence, protein sequence, viridiplantae, viridiplantae protein, nucleotide, sequence, protein, viridiplantae, workflow, software, database, bioinformatics, platform, genome, genomic analysis, analytic tool is listed by: OMICtools
is listed by: SoftCite
is related to: NCBI Nucleotide
is related to: NCBI Protein Database
is related to: UniProt
is related to: UniRef
is related to: EMBOSS
is related to: BioMoby
is related to: KEGG
has parent organization: Indiana University; Indiana; USA
has parent organization: University of South Dakota; South Dakota; USA
NSF 0090732;
NSF IOS-1126481
PMID:21546552
PMID:20865520
PMID:20150665
PMID:20054995
OMICS_01138 SCR_005397 BioExtract Server 2026-08-29 11:22:25 12
KGGSeq
 
Resource Report
Resource Website
50+ mentions
KGGSeq (RRID:SCR_005311) KGGSeq software resource A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data. The software platform, constituted of bioinformatics and statistical genetics functions, makes use of valuable biologic resources and knowledge for sequencing-based genetic mapping of variants / genes responsible for human diseases / traits. It facilitates geneticists to fish for the genetic determinants of human diseases / traits in the big sea of DNA sequences. KGGSeq has paid attention to downstream analysis of genetic mapping. The framework was implemented to filter and prioritize genetic variants from whole exome sequencing data. genomic, genetic, sequence, mutation, exome sequencing, disease, gene, variant, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Monogenic disorder, Cancer PMID:22241780 biotools:kggseq, OMICS_02260 https://bio.tools/kggseq SCR_005311 KGGSeq: A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data 2026-08-29 11:22:18 58
MAKER Web Annotation Service
 
Resource Report
Resource Website
1+ mentions
MAKER Web Annotation Service (RRID:SCR_005318) MWAS data access protocol, production service resource, service resource, software resource, web service The MAKER Web Annotation Service (MWAS) is an easily configurable web-accessible genome annotation pipeline. It''''s purpose is to allow research groups with small to intermediate amounts of eukaryotic and prokaryotic genome sequence (i.e. BAC clones, small whole genomes, preliminary sequencing data, etc.) to independently annotate and analyze their data and produce output that can be loaded into a genome database. MWAS is build on the stand alone genome annotation pipeline MAKER, and users who wish to annotate larger datasets and whole genomes are free to download MAKER for use on their own systems. MWAS identifies repeats, aligns ESTs and proteins to a genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MWAS can also automatically train popular gene prediction algorithms for use on new genomes for which pre-existing information is limited. MAKER is a member of the Generic Model Organism Database (GMOD) project and output produced by this site can be directly used with other GMOD tools. Annotations can be directly viewed online by the user via GBrowse, JBrowse, and Apollo, or they can be downloaded for local analysis and integration into a genome database. MWAS also supplies summary statistics on sequence features via the Sequence Ontology tool SOBA. MWAS should prove especially useful for emerging model organism genome projects with minimal bioinformatics expertise and computer resources, since a user can produce final genome annotations without having to install and configure any software locally. data management, human genome map, genome annotation, annotation, curation, genome, sequence is related to: MAKER
has parent organization: University of Utah; Utah; USA
nlx_144374 SCR_005318 2026-08-29 11:22:18 7
FaBox
 
Resource Report
Resource Website
100+ mentions
FaBox (RRID:SCR_005350) FaBox software resource Tools for splitting, joining and otherwise manipulating FASTA format sequence files. The first tools in the toolbox is for manipulating fasta headers, cropping alignments and doing some sequence comparison allowing users to combine the description of data (often in excel spreadsheets) with the actual data (often DNA sequences). Also, producing correct input files for a range of programs seems to be problematic for the average user. Hence, some converters in some of the services have been included as well as some stand-alone converters. The converters are not necessarily meant to provide the final input file, but you''ll get a valid input file for Arlequin, MrBayes etc. - that you may further edit so it suit your needs. This means that you may need to combine several of the tools to finish your handling - but it keeps it relatively simple to use. Please note that FaBox is written in PHP and ONLY RUNS ON A WEBSERVER. fasta, dna, protein sequence, dna sequence, protein, sequence, php is listed by: OMICtools
has parent organization: Aarhus University; Aarhus; Denmark
Acknowledgement requested OMICS_01165 SCR_005350 FaBox - an online fasta sequence toolbox 2026-08-29 11:22:25 120

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