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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
pyQPCR
 
Resource Report
Resource Website
pyQPCR (RRID:SCR_000471) pyQPCR software resource A GUI application written in python that deals with quantitative PCR (QPCR) raw data. Using quantification cycle values extracted from QPCR instruments, it uses a proven and universally applicable model to give finalized quantification resu quantitative pcr, python, qt is listed by: OMICtools
has parent organization: SourceForge
Free, Available for download, Freely available OMICS_02326 SCR_000471 2026-08-01 12:01:14 0
drFAST
 
Resource Report
Resource Website
1+ mentions
drFAST (RRID:SCR_000586) drFAST software resource A software which maps di-base reads (SOLiD color space reads) to reference genome assemblies in a fast and memory-efficient manner. di-base, solid color space, genome assemblies, memory-efficient, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: SourceForge
PMID:21586516 Free, Available for download, Freely available biotools:drfast, OMICS_00661 https://bio.tools/drfast SCR_000586 di-base read Fast Alignment Search Tool, drFAST: di-base read Fast Alignment Search Tool 2026-08-01 12:01:21 1
GMcloser
 
Resource Report
Resource Website
1+ mentions
GMcloser (RRID:SCR_000646) GMcloser software resource Software that fills and closes the gaps present in scaffold assemblies, especially those generated by the de novo assembly of whole genomes with next-generation sequencing (NGS) reads. Unlike other gap-closing tools that use only NGS reads, GMcloser uses preassembled contig sets or long read sets as the sequences to close gaps and uses paired-end (PE) reads and a likelihood-based algorithm to improve the accuracy and efficiency of gap closure. The efficiency of gap closure can be increased by successive treatments with different contig sets. scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:26261222 Free, Available for download, Freely available biotools:gmcloser, OMICS_00042 https://bio.tools/gmcloser SCR_000646 Gmcloser - Closing the gaps in scaffolds with preassembled contigs 2026-08-01 12:01:22 3
detecttd
 
Resource Report
Resource Website
detecttd (RRID:SCR_000681) detecttd software resource Software tool to detect tandem duplications in sequencing reads. It is written in Python and requires NCBI Blast standalone. tandem duplication, sequencing read, python, next-generation sequencing is listed by: OMICtools
has parent organization: SourceForge
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00315 SCR_000681 detecttd - Tool to detect tandem duplications in NGS reads 2026-08-01 12:01:28 0
FastUniq
 
Resource Report
Resource Website
1+ mentions
FastUniq (RRID:SCR_000682) software resource A software tool for removal of de novo duplicates in paired short DNA sequences. de novo, dna, sequence, duplicate, is listed by: OMICtools
has parent organization: SourceForge
DOI:10.1371/journal.pone.0052249 Free, Available for download, Freely available OMICS_01044 SCR_000682 2026-08-01 12:01:23 3
TriageTools
 
Resource Report
Resource Website
TriageTools (RRID:SCR_000675) TriageTools software resource A collection of tools for partitioning raw data (fastq reads) from high-throughput sequencing projects. The tools are designed for basic data management as well for prioritizing analysis of certain subsets. matlab, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23408855 Free, Available for download, Freely available biotools:triagetools, nlx_156740 https://bio.tools/triagetools SCR_000675 2026-08-01 12:01:17 0
NGS tools for the novice
 
Resource Report
Resource Website
1+ mentions
NGS tools for the novice (RRID:SCR_000664) NGS tools for the novice software resource A collection of simple Perl scripts adressed to scientists doing research that bases on high throughput genomic/transcriptomic data. It does not require any bioinformatic expertise. The scripts perform fundamental processing steps like sorting sequences by TAGs, FASTQ to FASTA conversion, filtering and counting of redundant sequences, individually adjustable FASTQ quality filtering or basic analyses like base count and analysis of sequence length distribution. next generation sequencing, perl is listed by: OMICtools
has parent organization: SourceForge
Free, Available for download, Freely available OMICS_01063 SCR_000664 NGS tools for the novice - Handy tools for processing of next generation sequencing (NGS) data 2026-08-01 12:01:17 3
Opera
 
Resource Report
Resource Website
1+ mentions
Opera (RRID:SCR_000665) software resource A sequence assembly software program that uses information from paired-end reads to optimally order and orient contigs assembled from shotgun-sequencing reads. sequence assembly, paired-end, orient contigs, shotgun-sequencing, shotgun, software program, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:27169502
PMID:21929371
Free, Available for download, Freely available biotools:opera, OMICS_00045 https://bio.tools/opera SCR_000665 OPERA-LG, Optimal Paired-End Read Assembler 2026-08-01 12:01:27 3
BioLemmatizer
 
Resource Report
Resource Website
1+ mentions
BioLemmatizer (RRID:SCR_000117) software resource A domain-specific lemmatization software tool for the morphological analysis of biomedical literature. standalone software is listed by: OMICtools
has parent organization: SourceForge
PMID:22464129 Free, Available for download, Freely available OMICS_04827 https://sourceforge.net/projects/biolemmatizer/ SCR_000117 2026-08-01 12:01:09 2
SOAPfuse
 
Resource Report
Resource Website
1+ mentions
SOAPfuse (RRID:SCR_000078) SOAPfuse software resource THIS RESOURCE IS NO LONGER IN SERVICE.Documented on August 23,2022. An open source tool developed for genome-wide detection of fusion transcripts from human being paired-end RNA-Seq data. This tool is a part of a larger set of tools to efficiently align oligonucleotides onto reference sequences . software, resource, open license, DNA sequencing, genome, transcripts, RNA, oligonucleotide is listed by: OMICtools
is listed by: SourceForge
is listed by: SOAP
PMID:23409703 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01357 SCR_000078 2026-08-01 12:01:09 7
Sequence Read Format
 
Resource Report
Resource Website
1+ mentions
Sequence Read Format (RRID:SCR_000132) SRF narrative resource, data or information resource, interchange format, standard specification A generic format for DNA sequence data. The primary motivation for creating SRF has been to enable a single format capable of storing data generated by any DNA sequencing technology. dna sequence, dna sequencing, interchange format is listed by: OMICtools
has parent organization: SourceForge
Public, A C++ implementation of Sequence Read Format is available OMICS_05130 SCR_000132 Sequence Read Format (SRF) 2026-08-01 12:01:08 1
exomeSuite
 
Resource Report
Resource Website
exomeSuite (RRID:SCR_000129) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A software application designed to analyze variant call files from next generation sequencing data to identify variants causing disease. standalone software, c, matlab is listed by: OMICtools
has parent organization: SourceForge
PMID:24603341 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04839 SCR_000129 2026-08-01 12:01:11 0
CG-Pipeline
 
Resource Report
Resource Website
CG-Pipeline (RRID:SCR_000047) software resource A software tool for assembling genome sequence data and running feature prediction and annotation tools on the assembly. perl has parent organization: SourceForge PMID:20519285 Free, Available for download, Freely available OMICS_04062 http://sourceforge.net/projects/cg-pipeline/ SCR_000047 2026-08-01 12:01:07 0
Batman-Seq
 
Resource Report
Resource Website
Batman-Seq (RRID:SCR_000048) Batman-Seq software resource A fast BWT-based short reads mapping tools which uses additional statistical method to model error profile of the sequencing experiment. c++ is hosted by: SourceForge Free, Available for download, Freely available OMICS_00651 SCR_000048 Basic Alignment Tool for MAny Nucleotides 2026-08-01 12:01:08 0
VariationHunter
 
Resource Report
Resource Website
10+ mentions
VariationHunter (RRID:SCR_004865) VariationHunter software resource A software tool for discovery of structural variation in one or more individuals simultaneously using high throughput technologies. structural variation, genome, next-generation sequencing is listed by: OMICtools
is related to: SPLITREAD
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: SourceForge
PMID:22048523
PMID:20529927
OMICS_00328 SCR_004865 VariationHunter-CommonLaw 2026-08-01 12:02:48 12
Pythia
 
Resource Report
Resource Website
10+ mentions
Pythia (RRID:SCR_004952) software resource Pythia is an open source thermodynamically oriented primer design python module. Pythia can be used in two ways. 1. Executable binaries only: under windows with cygwin and python 2.5 (built with mingw, that comes with the cygwin release). These executables allow the user to index DNA files for primer specificity search, design one primer pair per region, and tile regions with PCR amplicons. 2. A python module: under windows with cygwin, python2.5, numpy, swig, and mingw, or under linux with python2.4 or later, numpy, and swig (everything but numpy should be pre-installed on a normal linux system). The module gets you everything that the binaries get you, in a more pythonic framework. This package also includes modules for computing DNA binding and folding energies using the partition function approach with publicly available thermodynamic data. Usage documentation is in the downloads. has parent organization: SourceForge PMID:19528077 nlx_91969 SCR_004952 2026-08-01 12:02:47 42
cortex var
 
Resource Report
Resource Website
1+ mentions
cortex var (RRID:SCR_005081) cortex_var software resource A tool for genome assembly and variation analysis from sequence data. You can use it to discover and genotype variants on single or multiple haploid or diploid samples. If you have multiple samples, you can use Cortex to look specifically for variants that distinguish one set of samples (eg phenotype=X, cases, parents, tumour) from another set of samples (eg phenotype=Y, controls, child, normal). cortex_var features * Variant discovery by de novo assembly - no reference genome required * Supports multicoloured de Bruijn graphs - have multiple samples loaded into the same graph in different colours, and find variants that distinguish them. * Capable of calling SNPs, indels, inversions, complex variants, small haplotypes * Extremely accurate variant calling - see our paper for base-pair-resolution validation of entire alleles (rather than just breakpoints) of SNPs, indels and complex variants by comparison with fully sequenced (and finished) fosmids - a level of validation beyond that demanded of any other variant caller we are aware of - currently cortex_var is the most accurate variant caller for indels and complex variants. * Capable of aligning a reference genome to a graph and using that to call variants * Support for comparing cases/controls or phenotyped strains * Typical memory use: 1 high coverage human in under 80Gb of RAM, 1000 yeasts in under 64Gb RAM, 10 humans in under 256 Gb RAM genome assembly, variation analysis, sequence, variation, genotype variant, haploid, diploid, snp, indel, inversion, variant, haplotype, de novo assembly, genotyping, variant-calling, population analysis, population assembly is listed by: OMICtools
has parent organization: SourceForge
has parent organization: Wellcome Trust Centre for Human Genetics
PMID:22231483 GNU General Public License, v3, Acknowledgement requested OMICS_00056 SCR_005081 cortex_var - for variant and population assembly 2026-08-01 12:02:54 3
Bambus
 
Resource Report
Resource Website
Bambus (RRID:SCR_005068) Bambus software resource Software for scaffolding to address some of the challenges encountered when analyzing metagenomes. Scaffolding represents the task of ordering and orienting contigs by incorporating additional information about their relative placement along the genome. While most other scaffolders are closely tied to a specific assembly program, Bambus accepts the output from most current assemblers and provides the user with great flexibility in choosing the scaffolding parameters. In particular, Bambus is able to accept contig linking data other than specified by mate-pairs. Such sources of information include alignment to a reference genome (Bambus can directly use the output of MUMmer), physical mapping data, or information about gene synteny. scaffolding is listed by: OMICtools
has parent organization: SourceForge
PMID:21926123 Open unspecified license OMICS_01432 http://sourceforge.net/apps/mediawiki/amos/index.php?title=Bambus SCR_005068 Bambus 2, Bambus 2.0 2026-08-01 12:02:53 0
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/, https://bio.tools/g-blastn SCR_005062 2026-08-01 12:02:45 0
VFS
 
Resource Report
Resource Website
1+ mentions
VFS (RRID:SCR_005138) VFS software resource A versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. It combines soft-clipping information, read-pair analysis, and targeted de novo assembly to discover and annotate viral-human fusion events. A simple yet effective empirical statistical model is used to evaluate the quality of fusion breakpoints. Minimal user defined parameters are required. ubuntu, debian, high-throughput sequencing, virus, reconstruct, fusion transcript, transcript, integration, fusion, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23314323 GNU General Public License, v3 OMICS_00224, biotools:viralfusionseq https://bio.tools/viralfusionseq SCR_005138 ViralFusionSeq, ViralFusionSeq (VFS) 2026-08-01 12:02:56 1

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