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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.brown.edu/research/projects/superfund/cores/core-d
Core provides equipment and technical expertise for evaluation of molecular and morphological changes in cells, tissues, and organs following exposure to complex environmental contaminants. Provides equipment, including automated tissue processor, paraffin embedding center, two automated microtomes, cryostat, vibratome for soft-tissue sectioning, multiheaded light microscope with projection capabilities, system for laser capture microdissection, and slide scanner with analysis software for identification and quantification of morphological structures.Offers expertise in histopathological and immunocytochemial methods, including fixation, dehydration, embedding, sectioning, histological staining, immunolabeling, high-resolution imaging, and quantitative image analysis. Services in sample preparation, offers assistance in imaging and image analysis and provides consultation for ongoing or future research projects, training program for students and investigators who use centrally available equipment.
Proper citation: Brown University Molecular Pathology Core Facility (RRID:SCR_017898) Copy
https://www.igb.illinois.edu/corefacilities
Core for biological microscopy and image analysis. Offers high-end equipment,user training,ongoing support, including experiment design and data interpretation,twenty-four hour access Services,3D Printing, Transfer Files, Image Analysis,Histology,Instrument Training.
Proper citation: University of Illinois at Urbana-Champaign Core Facilities at IGB (RRID:SCR_017938) Copy
Core provides access to fluorescence microscopy equipment including Deltavision OMX Blaze Super Resolution (3D-SIM/SMLM), Leica SP8 inverted confocal, La Vision Ultramicroscope II Lightsheet Microscope,Nikon Andor WD spinning disk, Nikon A1R inverted confocal x2, Olympus FV-MPERS Multi Photon,Olympus FV3000 inverted confocal (live cell) ISS Fast-FLIM, Perkin Elmer Operetta High Content Imaging, Zeiss LSM800 upright Airyscan, Zeiss LSM880 upright Airyscan fast, Zeiss Elyra/LSM880 inverted (live cell), super resolution (Airyscan/SMLM). Staff can help with image analysis, super resolution microscopy, fluorescence lifetime imaging microscopy, high content imaging and light sheet microscopy techniques.
Proper citation: University of Melbourne Biological Optical Microscopy Platform (BOMP) Core Facility (RRID:SCR_018888) Copy
https://site.research.utexas.edu/cbrs/
Facility provides access to and operational support for easy-to-operate equipment for sample preparation and analysis, including gel imagers, plate readers, and qPCRs. They provide training on instrument operation and grant access for independent use after completed training.
Proper citation: University of Texas at Austin Shared Instrumentation Facility (RRID:SCR_026271) Copy
Core laboratory for nucleic acid sequencing and bioinformatics. Used for research support, education, and training. Services include genomic techniques and applications, sequencing technologies, and bioinformatics analyses, writting letters of support for grant applications submitted to funding agencies. GGBC operates multiple platforms for short-, long-, and single-molecule sequencing reads (i.e., Illumina MiSeq and NextSeq, PacBio Sequel, and Oxford Nanopore MinIon).
Proper citation: Georgia Genomics and Bioinformatics Core at the University of Georgia (RRID:SCR_010994) Copy
https://icahn.mssm.edu/research/human-immune-monitoring-center
Core provides team of experts in the characterization of immune profiles and treatment responses across a diverse range of diseases, such as cancer, autoimmunity, allergy, and neuro-immune disorders. Offers equipment in the field for research at Genomic, cellular and proteomic analysis. Develops assays to balance innovation with protocols and operating procedures to ensure data quality and reproducibility.
Proper citation: Icahn School of Medicine at Mount Sinai Human Immune Monitoring Center Core Facility (RRID:SCR_027571) Copy
http://www.med.upenn.edu/molecular/core_morphology.shtml
Core facility that provides histological services, equipment usage, and technical expertise to digestive and liver research projects.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Molecular Pathology and Imaging Core (RRID:SCR_015618) Copy
http://www.multichannelsystems.com/products/mea2100-systems
In vitro recording system for electrophysiology research with integrated amplifier and stimulus generator, temperature control, and the option for real-time signal detection and feedback. The system can record up to 4 MEAs in parallel at a sampling rate of 50 kHz per channel.
Proper citation: HBio: Multichallel Systems: MEA2100 System (RRID:SCR_014809) Copy
http://www.pacifictranscription.com.au/philips-dvt-2700.php
Software and accompanying hardware for transcription and voice recording. Software is Windows-compatible only and comes in a physical CD.
Proper citation: Philips DVT2700 Voice Tracer Digital Recorder with Dragon NaturallySpeaking software (RRID:SCR_014800) Copy
Commercial organization, located in Houstion, Texas, USA, for products for magnetic resonance spectroscopy. Manufactures NMR, NQR and amp, MRI instrumentation including nuclear magnetic resonance spectrometers and full consoles, system upgrades, and solid-state NMR / NQR probes. Tecmag was acquired by Avingtrans PLC and became subsidary of Scientific Magnetics Ltd. (UK).
Proper citation: Tecmag (RRID:SCR_017369) Copy
https://sciex.com/products/mass-spectrometers/qtof-systems/tripletof-systems/tripletof-5600-system
Mass spectrometry system that combines SCIEX Triple Quad technology with Accelerator TOF Analyzer, to deliver nominal mass and accurate mass benefits in single platform. Integrates comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation workflows.
Proper citation: SCIEX: TripleTOF 5600+ Mass Spectrometer System (RRID:SCR_018053) Copy
Real-time PCR system that performs high performance, multicolor real-time PCR. Has five color platform that is calibrated for broadest range of dyes available: FAM, SYBR Green I, VIC, JOE, NED, TAMRA, Cy3, ROX, Texas Red, and Cy5 dyes. Thermal cycling block is built to reduce environmental exposure and contamination risk.
Proper citation: Thermo Fisher: Applied Biosystems: 7500 Real-Time PCR System (RRID:SCR_018051) Copy
Benchtop flow cytometer features reliable performance and accurate results for experiments requiring up to 10 parameters. Fixed alignment flow cell minimizes startup time and improves reproducibility. Patented optical design maximizes signal detection and increases sensitivity and resolution for each color in multicolor assay.
Proper citation: BD Biosciences: Canto II Flow Cytometer (RRID:SCR_018056) Copy
Thermo Fisher Ion Torrent Sequencer. Semiconductor based next generation sequencing system that enables simple targeted sequencing workflows. With cartridge based reagents, system is simple to use and offers scalability and flexibility. Uses Ion 5 Series chips to support broad range of forensic applications including mitochondria sequencing, STR analysis, and SNP genotyping.
Proper citation: Thermo Fisher: HID Ion GeneStudio S5 Prime System (RRID:SCR_017984) Copy
https://www.laboratorynetwork.com/doc/leo-1525-field-emission-scanning-electron-mic-0001
Field emission scanning electron microscope that performs ultra high resolution imaging and analysis. Designed for requirements of nano-analysis, chamber of LEO 1525 is capable of accommodating both EDS and full-focusing Wavelength-dispersive X-ray spectroscopy WDS spectrometers as well as rage of other accessories. Coincident and short working distances allow signals from these detectors to be acquired simultaneously.
Proper citation: Zeiss: LEO 1525 Field Emission Scanning Electron Microscope (RRID:SCR_018039) Copy
https://assets.thermofisher.com/TFS-Assets/LSG/Application-Notes/PGM-Specification-Sheet.pdf
Thermo Fisher Ion Torrent Sequencer. System combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data. Coupled with Torrent Suite Software performs preliminary reference genome alignment and outputs data in BAM format for easy downstream analysis with optional third party analysis tools. It can also provide access to web portal for data review and sharing.
Proper citation: Thermo Fisher: Ion Personal Genome Machine System (RRID:SCR_017983) Copy
Multimode microplate reader that provides speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Provides higher sensitivity for time-resolved fluorescence TRF applications, and Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments GxP.
Proper citation: Perkin Elmer: EnVision 2105 Multimode Plate Reader (RRID:SCR_018038) Copy
Thermo Fisher Ion Torrent Sequencer. Ion Proton System for Next-Generation Sequencing. Used for accurate high-throughput sequencing.
Proper citation: Thermo Fisher: Ion Proton System (RRID:SCR_017982) Copy
http://www.syntechinnovation.com/images/catalog/advance-analytical/8chromatography/HPLC_Brochure.pdf
Liquid chromatography analyzer that achieves high levels of sample throughput by use of either binary or quaternary pumps and interchangeable autosamplers. High pressure operation and use of short columns with small diameter media result in fast, high resolution separations. Features includedu al-lamp design and temperature control of diode array detectors.
Proper citation: Agilent: 1200 High Performance Liquid Chromatography System (RRID:SCR_018037) Copy
https://microscopy.nri.ucsb.edu/instrumentation/jeol-1230-transmission-electron-microscope
High performance, high contrast, 40-120kV transmission electron microscope that performs imaging for biological and materials science applications.
Proper citation: JEOL: 1230 Transmission Electron Microscope (RRID:SCR_018036) Copy
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