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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://harvard.eagle-i.net/i/0000012e-97d7-0e06-55da-381e80000000
Core facility that provides the following services: Breeding pair service, Mouse Phenotyping Services.
This resource provides to MGH investigators a local source of breeding pairs of the 22 chromosome substitution strains (CSS)* of mice and access to basic phenotyping equipment for mapping of simple or complex traits, to promote the use of genetic mouse-based strategies in basic and clinical research. The CSS Resource comprises 22 mouse lines, each homozygous for a single A/J chromosome (Chr 1-19, X or Y and mitochondria) on a genetic background that is otherwise C57BL/J that were generated by Dr. Joseph Nadeau (Case Western Reserve University) and his colleagues. The CSS mice are available from The Jackson Laboratories. However, to save time and money, the MGH CSS Resource maintains CSS breeding colonies that are housed in the Simches-8 barrier facility, adjacent to a procedure room that will have equipment for basic standardized phenotyping, including behavioral and metabolic measurements.
Proper citation: MGH CHGR Chromosome Substitution Strain Resource (RRID:SCR_009916) Copy
http://eagle-i.itmat.upenn.edu/i/0000013b-1a8e-a29f-83a0-df0880000000
This Research Core provides training and research support in genotyping and quantification of nucleic acids. The Core facility has equipment needed to genotype DNA samples and to measure nucleic acid concentrations in isolation or in tissue samples.
Proper citation: Monell Genotyping and DNA/RNA Analysis Core (RRID:SCR_009957) Copy
http://eagle-i.itmat.upenn.edu/i/0000013c-48fe-35e0-f162-a2b280000000
Monell''s Behavioral and Physiological Phenotyping Core provides training and research support in the behavioral and physiological phenotyping of rodents, including surgical and electrophysiological techniques utilized in rodent models. Core personnel offer expertise, instruction and equipment needed for methodologies common to research in the chemical senses, including preference tests, gustometers, olfactometers, LabMaster systems and metabolic cages.
Proper citation: Monell Behavioral and Physiological Phenotyping Core (RRID:SCR_009955) Copy
http://meharry.eagle-i.net/i/00000135-2fc1-b5b8-9658-54ab80000000
Core facility that provides the following services: Confocal and wide-field microscopy services, Confocal and wide-field microscopy training. It is the mission of the Meharry Medical College Morphology Core to provide the expertise and state-of-the-art instrumentation necessary to facilitate and enhance the productivity of Meharry?s investigators and trainees in the areas of fluorescence and bright-field microscopy and immunohistochemistry. This core strives to accomplish this by offering consultation on instrumentation and experimental design, training on instrumentation, and collaboration opportunities. We do our utmost to stay on the cutting edge of technology, skills, and knowledge in the field.
Proper citation: Meharry Morphology Core (RRID:SCR_009954) Copy
http://harvard.eagle-i.net/i/00000135-342b-fcc8-0fb7-ab1580000000
Core facility that provides the following services: 9.4T Facility rodent, nonhuman primate, and small animal proton spectroscopy. The McLean Hospital Translational Imaging Laboratory aims to provide cutting edge magnetic resonance imaging, functional imaging, chemical imaging (spectroscopy), and multimodal imaging services to the Harvard Catalyst Community. We have 3 magnetic resonance (MR) scanners, an ultra high magnetic field (9.4 Tesla) dedicated animal scanner and 3.0 and 4.0 Tesla large bore human systems available for large animal scans. Our scanners are capable of conducting scans in animals ranging in size from mice to large dogs, and we have experience imaging mice, rats, rabbits, nonhuman primates, and several canine species. All 3 scanners have dedicated animal prep areas. We offer high level biophysics, engineering, and data analytic expertise, along with veterinary technologist anesthesia support.
Proper citation: McLean Translational Imaging Laboratory (RRID:SCR_009948) Copy
http://meharry.eagle-i.net/i/00000135-2f8e-6f62-9658-54ab80000000
The Endocrine Core Laboratory is a fully accredited, CLIA approved, endocrine testing facility funded by the Meharry Medical College Clinical Research Center, U54 Reproductive Health Grants, and institutional resources. The Endocrine Core Lab performs a comprehensive list of routine and specialized endocrine tests on blood samples for government funded investigators... A full staff of board certified clinical endocrinologists and clinical scientists are available for consultation and interpretation of test results.
Proper citation: Meharry Endocrine core (RRID:SCR_009949) Copy
http://montana.eagle-i.net/i/0000012b-00be-f31e-df3b-3fdc80000000
Core facility that provides the following services: Training and access, Elemental spectroscopic imaging, Thin section imaging, Shadow casting, Negative staining, Electron diffraction, Brightfield imaging.
This facility is a resource center for transmission electron microscopy, providing investigators with consultation, training, access to equipment and other services.
Proper citation: MSU Transmission Electron Microscopy Core Laboratory (RRID:SCR_009946) Copy
http://montana.eagle-i.net/i/0000012e-ee8a-2493-4efe-ddcc80000000
Core facility that provides the following services: Data management solutions, Managed server hosting, Storage and computation, Software development, IT consulting and training.
Researchers face increasing challenges managing IT infrastructure. From software and servers, to data storage and back-ups, the Research Computing Group (RCG) is here to help you with all your IT needs as a researcher at MSU. We have the expertise to provide infrastructure for projects ranging from large-scale computation and storage to small-scale hosting. Contact us to find out how we can help you.
Proper citation: MSU Research Computing Group (RRID:SCR_009945) Copy
http://montana.eagle-i.net/i/0000012b-00be-8638-df3b-3fdc80000000
Core facility that provides the following services: Tissue harvest, Inoculation, Surgery, Large research animal husbandry. The MSU Large Animal BSL-2 is a specially designed facility providing research space to house larger research animals (<400 lbs) with BSL-2 containment for immunology and infectious disease experiments.
Proper citation: MSU Large animal BSL-2 (RRID:SCR_009941) Copy
https://cancer.dartmouth.edu/scientists-researchers/clinical-pharmacology
Supports Dartmouth Cancer Center investigators in design, performance, data analysis, and interpretation of pharmacology objectives in preclinical, clinical and epidemiological studies.
Proper citation: Dartmouth College Clinical Pharmacology Shared Resource Core Facility (RRID:SCR_000873) Copy
http://harvard.eagle-i.net/i/0000012e-6e60-8691-55da-381e80000000
Core facility that provides the following services: Website development and hosting for research labs and studies requiring an online presence, interactive functionality, or site traffic tracking.
The Health Communication Core offers a full range of creative communication services to support evidence-based recruitment and retention of study participants and intervention research. HCC serves researchers from diverse disciplines who need websites, logos, brochures, social media campaigns, publications, and interactive media targeted to the needs and preferences of specific audiences.
Proper citation: DF/HCC Health Communication Core (RRID:SCR_000871) Copy
http://montana.eagle-i.net/i/0000012b-1707-0c83-e53c-c6d280000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A suite of laboratories that study the effect of the cold on projects across several scientific disciplines. These facilities have the ability to simulate other environmental conditions such as solar radiation and humidity in addition to subzero temperatures.
Proper citation: MSU Subzero Science and Engineering Research Core Facility (RRID:SCR_000227) Copy
http://ohsu.eagle-i.net/i/0000012a-24fd-8f6b-d994-629180000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: MRI examination of sedated non-human primate subjects. The magnetic resonance imaging (MRI) core provides ONPRC investigators with equipment and assistance to perform MRI exams of sedated NHP subjects.
Proper citation: OHSU MRI Support Core Laboratory (RRID:SCR_000228) Copy
http://eagle-i.itmat.upenn.edu/i/00000138-7c61-ea3e-fbab-3b8480000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Core facility that provides the following services: Maintenance of transgenic or mutant zebrafish lines, Zebrafish research training, Zebrafish embryo supply service. The CDB Zebrafish Core facility provides services and training to Penn faculty interested in using the zebrafish model system as part of their research program.
Proper citation: Penn Cell and Developmental Biology Zebrafish Core (RRID:SCR_000300) Copy
http://eagle-i.itmat.upenn.edu/i/00000138-7c3c-ea6b-fbab-3b8480000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Core facility that provides the following services: Clinical data management, Project operations and compliance support, Custom database application development, Research technology support, Proposal development service. The Clinical Research Computing Unit (CRCU) is a designated core research facility within Penn Medicine, specializing in clinical research informatics (CRI) collaboration and research IT services with a growing number of clinical and translational research investigators at Penn. The CRCU currently supports 58 funded projects, valued at more than $336 M (total costs, all years) to Penn. Although situated within the Center for Clinical Epidemiology and Biostatistics (CCEB), the CRCU supports an increasing volume of its research portfolio led by PIs external to the CCEB. This year the total value of these research programs was $ 243 M, so that the proportion attributable to PIs external to CCEB exceeded 70% ($243 M / $336 M = 72%). Established originally on April 1, 1997, within the Biostatistics Unit of the Center for Clinical Epidemiology and Biostatistics (CCEB) at the University of Pennsylvania School of Medicine, the primary foci were to develop a research computing base for the new program in Biostatistics, as well as to create the capacity and resources to compete successfully for data coordinating centers (DCCs) of federally funded, large-scale, multi center clinical trials, and epidemiological studies. These technology resources also permitted CCEB faculty and staff to provide essential collaborative CRI support for Penn investigators throughout the wide array of basic science and clinical departments, centers, and institutes, thus enhancing their likelihood of funding success. On July 1, 2002, the CRCU restructured its operations and expanded its focus in response to the overall research project growth within the CCEB and the University. The CRCU, as an organizational unit, moved from within the Biostatistics Unit of the CCEB to a CCEB-wide organizational service center for both the Biostatistics and Clinical Epidemiology units. With this restructuring, the CRCU now has two faculty co-directors; one representing each of the CCEB units. The faculty directors ensure that the overall strategy and goals of the service center are aligned with the overall goals of the CCEB, as well as Penn Medicine. In 2005, the leadership model was expanded with the appointment of four (4) Directors of Operations, each of whom report directly to the faculty directors and manage a specialty sub-unit of staff to more effectively coordinate the evolving complexities of the more than 58 sponsored project teams. The original two (2) Senior Directors now focus their leadership efforts on technology infrastructure, new methodologies, special projects and fostering strategic collaborations with other Penn departments, commercial vendors, and other institutions. The University of Pennsylvania aspires to excellence in all domains. The CRCU embraces these ideals, as it partners with faculty and staff to conduct biomedical, behavioral, clinical and translational biomedical research at the highest levels of excellence. Advances in healthcare and improvements in quality of life through research depend on thoughtful science and uncompromising integrity in the collection and handling of information. The CRCU excels in the support of biomedical and clinical research by providing expertise in all facets of research information management, and by understanding the regulatory and cultural environments in which research is conducted. The CRCU fosters collaborative relationships with investigators in the CCEB, other Centers and Institutes throughout the School of Medicine, and across the University, to take an active partnership role in meeting their research goals. The CRCU is committed to continuous improvement in the expertise offered and the services provided, through an emphasis on education and training for staff and through the use of leading technologies and creative solutions.
Proper citation: Penn Clinical Research Computing Unit (RRID:SCR_000301) Copy
https://www.ohsu.edu/dna-services-core
Services offered include Human cell line authentication: Accurate validation of human cell lines using STR analysis and meeting the ANSI/ATCC requirements; Fragment analysis: Detection of changes in length of specific DNA sequence to indicate presence or absence of genetic marker; Oligo synthesis: Creation of custom primers and probes for oligo and siRNA synthesis through Integrated DNA Technologies (IDT); DNA quantification: Quantification, size and quality assessment of DNA samples; Consulting: For project design and sample preparation assistance.
Proper citation: OHSU DNA Services Core Facility (RRID:SCR_009968) Copy
https://www.med.upenn.edu/scxc/
Offers in vivo services specializing in immunodeficient and xenograft models (PDX, humanized immune system). Facility has dedicated BSL2 barrier space equipped with optical imaging, for applications ranging from immunotherapy, cancer biology, infectious diseases and regenerative medicine. Offers services centered around repository of live and fully annotated cells from adult patients with hematologic malignancies (AML, ALL, MPN, MDS), and hematopoietic stem/progenitor cells from healthy donors (BM, CB, and FL).
Proper citation: Pennsylvania University Perelman School of Medicine Stem Cell and Xenograft Core Facility (RRID:SCR_010035) Copy
http://www.dfhcc.harvard.edu/core-facilities/dna-resource/
A centralized laboratory that provides DNA sequencing and plasmid clone storage and distribution services to researchers in the DF/HCC community and around the world. It provides the following services: Large-scale DNA sequencing service, Small-scale DNA sequencing service, Same-day sequencing service, Automated, high-throughput plasmid DNA preparations, Chain termination sequencing service, DNA extraction service. The DNA Resource Core was started to meet a growing need for DNA sequencing services at a cost that is affordable for academic labs. Our services now include DNA sequencing for large- and small-scale projects and a plasmid repository & distribution service. Our highest priorities are quality assurance, user support and timely request fulfillment. Questions about the plasmid repository can also be directed to plasmidhelp(at)hms.harvard.edu.
Proper citation: DF/HCC DNA Resource Core (RRID:SCR_012676) Copy
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