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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Bandage
 
Resource Report
Resource Website
10+ mentions
Bandage (RRID:SCR_022772) data processing software, software application, software resource, data analysis software Software tool for visualising de novo assembly graphs. By displaying connections which are not present in contigs file, opens up new possibilities for analysing de novo assemblies. Used for interactive visualization of de novo genome assemblies. interactive visualization, de novo genome assemblies, visualising de novo assembly graphs, analysing de novo assemblies is listed by: Debian
is listed by: OMICtools
PMID:26099265 Free, Available for download, Freely available OMICS_09013 https://github.com/rrwick/Bandage, https://sources.debian.org/src/bandage/ SCR_022772 Bioinformatics Application for Navigating De novo Assembly Graphs Easily 2026-08-04 09:45:06 21
AmphoraNet
 
Resource Report
Resource Website
10+ mentions
AmphoraNet (RRID:SCR_005009) AmphoraNet data analysis service, analysis service resource, production service resource, service resource Webserver implementation of the AMPHORA2 workflow for phylogenetic analysis of metagenomic shotgun sequencing data. It is capable of assigning a probability-weighted taxonomic group for each phylogenetic marker gene found in the input metagenomic sample. dna sequence, amino acid sequence, dna, sequence, amino acid, phylogenetic, reliability score, nucleotide, protein, nucleotide sequence, protein sequence, phylogenetic analysis, metagenomic, metagenomics, phylotyping, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Eotvos Lorand University; Budapest; Hungary
PMID:24144838 Acknowledgement requested, Free, Public biotools:amphoranet, OMICS_01450 https://bio.tools/amphoranet SCR_005009 2026-08-04 09:41:16 16
MLTreeMap
 
Resource Report
Resource Website
1+ mentions
MLTreeMap (RRID:SCR_004792) MLTreeMap data analysis service, analysis service resource, production service resource, service resource Data analysis service that analyzes DNA sequences and determines their most likely phylogenetic origin. Its main use is in metagenomics projects, where DNA is isolated directly from natural environments and sequenced (the organisms from which the DNA originates are often entirely undescribed). It will search such sequences for suitable marker genes, and will use maximum likelihood analysis to place them in the ''''Tree of Life''''. This placement is more reliable than simply assessing the closest relative of a sequence using BLAST. More importantly, MLTreeMap decides not only who is the closest relative of your query sequence, but also how deep in the tree of life it probably branched off. Additionally, MLTreeMap searches the sequences for genes, which are coding for key enzymes of important functional pathways, such as RuBisCo, methane monooxygenase or nitrogenase. In case of a positive hit, MLTreeMap uses maximum likelihood analysis to place them in the respective ''''gene-family tree''''. phylogeny, gene, fasta, dna sequence, nucleotide sequence, metagenomics, metagenome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: COG
has parent organization: University of Zurich; Zurich; Switzerland
PMID:20687950 biotools:mltreemap, OMICS_01457 https://bio.tools/mltreemap SCR_004792 Phylogenetic analysis of metagenomics sequence data 2026-08-04 09:41:13 4
BioSample Database at EBI
 
Resource Report
Resource Website
10+ mentions
BioSample Database at EBI (RRID:SCR_004856) BioSD database, data or information resource Database that aggregates sample information for reference samples (e.g. Coriell Cell lines) and samples for which data exist in one of the EBI''''s assay databases such as ArrayExpress, the European Nucleotide Archive or PRoteomics Identificates DatabasE. It provides links to assays for specific samples, and accepts direct submissions of sample information. The goals of the BioSample Database include: # recording and linking of sample information consistently within EBI databases such as ENA, ArrayExpress and PRIDE; # minimizing data entry efforts for EBI database submitters by enabling submitting sample descriptions once and referencing them later in data submissions to assay databases and # supporting cross database queries by sample characteristics. The database includes a growing set of reference samples, such as cell lines, which are repeatedly used in experiments and can be easily referenced from any database by their accession numbers. Accession numbers for the reference samples will be exchanged with a similar database at NCBI. The samples in the database can be queried by their attributes, such as sample types, disease names or sample providers. A simple tab-delimited format facilitates submissions of sample information to the database, initially via email to biosamples (at) ebi.ac.uk. Current data sources: * European Nucleotide Archive (424,811 samples) * PRIDE (17,001 samples) * ArrayExpress (1,187,884 samples) * ENCODE cell lines (119 samples) * CORIELL cell lines (27,002 samples) * Thousand Genome (2,628 samples) * HapMap (1,417 samples) * IMSR (248,660 samples) cell line, cell, nucleotide, sequencing, proteomics, peptide, protein, genomics, gene expression, biological sample, molecular, sequence, structure, cell line, topical portal, aggregator, gold standard, bio.tools uses: European Nucleotide Archive (ENA)
uses: Proteomics Identifications (PRIDE)
uses: ArrayExpress
uses: ENCODE
uses: Coriell Institute for Medical Research
uses: 1000 Genomes: A Deep Catalog of Human Genetic Variation
uses: International HapMap Project
uses: International Mouse Strain Resource
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BioSample
has parent organization: European Bioinformatics Institute
European Molecular Biology Laboratory; Heidelberg; Germany ;
European Union FP7 HEALTH-F4-2010-241669;
European Union FP7 HEALTH-F4-2007-201413
PMID:22096232 The community can contribute to this resource, Acknowledgement requested biotools:biosamples, r3d100012628, nlx_143930, OMICS_01025 https://bio.tools/biosamples, https://doi.org/10.17616/R37R3P SCR_004856 BioSamples database, BioSamples, BioSamples Database at EBI, BioSample Database at the EBI, EBI BioSample Database, BioSample Database, BioSD at EBI, BioSD - BioSample Database 2026-08-04 09:41:14 14
SGD
 
Resource Report
Resource Website
1000+ mentions
SGD (RRID:SCR_004694) SGD, SGD LOCUS, SGD REF database, data or information resource A curated database that provides comprehensive integrated biological information for Saccharomyces cerevisiae along with search and analysis tools to explore these data. SGD allows researchers to discover functional relationships between sequence and gene products in fungi and higher organisms. The SGD also maintains the S. cerevisiae Gene Name Registry, a complete list of all gene names used in S. cerevisiae which includes a set of general guidelines to gene naming. Protein Page provides basic protein information calculated from the predicted sequence and contains links to a variety of secondary structure and tertiary structure resources. Yeast Biochemical Pathways allows users to view and search for biochemical reactions and pathways that occur in S. cerevisiae as well as map expression data onto the biochemical pathways. Literature citations are provided where available. database, yeast, pathway, analysis, gene, nomenclature, predicted sequence, fungi, functional relationship, protein structure, bio.tools, FASEB list uses: InterMOD
is used by: NIF Data Federation
is used by: PhenoGO
is listed by: re3data.org
is listed by: OMICtools
is listed by: InterMOD
is listed by: bio.tools
is listed by: Debian
is affiliated with: InterMOD
is related to: AmiGO
is related to: Yeast Search for Transcriptional Regulators And Consensus Tracking
is related to: HomoloGene
is related to: TXTGate
is related to: PhenoGO
has parent organization: Stanford University School of Medicine; California; USA
has parent organization: Stanford University; Stanford; California
is parent organization of: Ascomycete Phenotype Ontology
is parent organization of: SGD Gene Ontology Slim Mapper
is organization facet of: Alliance of Genome Resources
NHGRI 5P41HG001315-11;
NHGRI 5P41HG002273-05;
NHGRI 5U41HG001315-18;
NHGRI 2U41HG002273-13;
NHGRI 5R01HG004834-04
PMID:24265222
PMID:12519985
PMID:9399804
Free for academic use, The community can contribute to this resource, Non-commercial nif-0000-03456, biotools:sgd, r3d100010419, OMICS_01661 https://bio.tools/sgd, https://doi.org/10.17616/R3N313 http://genome-www.stanford.edu/Saccharomyces/ SCR_004694 SGD LOCUS, Saccharomyces Genome Database, SGD REF 2026-08-04 09:41:12 1920
Pfam
 
Resource Report
Resource Website
10000+ mentions
Pfam (RRID:SCR_004726) database, data or information resource A database of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs). Users can analyze protein sequences for Pfam matches, view Pfam family annotation and alignments, see groups of related families, look at the domain organization of a protein sequence, find the domains on a PDB structure, and query Pfam by keywords. There are two components to Pfam: Pfam-A and Pfam-B. Pfam-A entries are high quality, manually curated families that may automatically generate a supplement using the ADDA database. These automatically generated entries are called Pfam-B. Although of lower quality, Pfam-B families can be useful for identifying functionally conserved regions when no Pfam-A entries are found. Pfam also generates higher-level groupings of related families, known as clans (collections of Pfam-A entries which are related by similarity of sequence, structure or profile-HMM). database, clan, structure, sequence, protein family, domain, bio.tools, FASEB list is used by: Mutation Annotation and Genomic Interpretation
is used by: MobiDB
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Conserved Domain Database
is related to: SUPFAM
is related to: DBD: Transcription factor prediction database
is related to: DOMINE: Database of Protein Interactions
is related to: GeneSpeed- A Database of Unigene Domain Organization
is related to: Eukaryotic Linear Motif
is related to: TopoSNP
is related to: GOTaxExplorer
is related to: TrED
is related to: ProOpDB
is related to: Algal Functional Annotation Tool
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
EMBL core funds ;
Howard Hughes Medical Institute ;
BBSRC BB/L024136/1;
Wellcome Trust 108433/Z/15/Z
PMID:24288371
PMID:19920124
Acknowledgement requested, Available via FTP biotools:pfam, OMICS_01696, r3d100012850, nlx_72111 https://bio.tools/pfam, https://doi.org/10.17616/R3QV4F http://pfam.sanger.ac.uk/ SCR_004726 Pfam Database, Protein Families Database, PFAM, Pfam protein families database 2026-08-04 09:41:12 15523
IBIS: Inferred Biomolecular Interactions Server
 
Resource Report
Resource Website
1+ mentions
IBIS: Inferred Biomolecular Interactions Server (RRID:SCR_004886) IBIS database, data or information resource A web server and database that organizes, analyzes and predicts interactions between proteins and other biomolecules. For a given protein sequence or structure query, it reports protein-protein, protein-small molecule, protein nucleic acids and protein-ion interactions observed in experimentally-determined structural biological assemblies. It also infers/predicts interacting partners and binding sites by homology, by inspecting the protein complexes formed by close homologs of a given query. To ensure biological relevance of inferred binding sites, the IBIS algorithm clusters binding sites formed by homologs based on binding site sequence and structure conservation. protein interaction, protein protein, protein small molecule, protein nucleic acid, protein ion interaction, interacting partner, binding site, homology, protein complex, structure conservation, nucleic acid, protein dna, protein rna, protein chemical, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: NCBI Structure
has parent organization: NCBI
PMID:22102591
PMID:19843613
OMICS_01917, biotools:ibis_ncbi, nlx_85682 https://bio.tools/ibis_ncbi SCR_004886 Inferred Biomolecular Interactions Server, NCBI Inferred Biomolecular Interactions Server 2026-08-04 09:41:14 5
SGN
 
Resource Report
Resource Website
500+ mentions
SGN (RRID:SCR_004933) SGN, SGN ref database, data or information resource A clade oriented, community curated database containing genomic, genetic, phenotypic and taxonomic information for plant genomes. Genomic information is presented in a comparative format and tied to important plant model species such as Arabidopsis. SGN provides tools such as: BLAST searches, the SolCyc biochemical pathways database, a CAPS experiment designer, an intron detection tool, an advanced Alignment Analyzer, and a browser for phylogenetic trees. The SGN code and database are developed as an open source project, and is based on database schemas developed by the GMOD project and SGN-specific extensions. database, clade, genomic, sequence, phenotype, pathway, genetic, taxonomy, annotation, blast, plant genome, bio.tools, FASEB list is used by: NIF Data Federation
is listed by: bio.tools
is listed by: Debian
is related to: Sol Genomics Network - Bulk download
is related to: AmiGO
has parent organization: Boyce Thompson Institute for Plant Research
USDA ;
ATC Inc. Advanced Technologies Cambridge ;
NSF 0116076;
NSF 9872617;
NSF 975866;
NSF 0421634
PMID:20935049
PMID:16010005
Public, The community can contribute to this resource r3d100012078, nlx_89764, biotools:sol_genomics_network https://bio.tools/sol_genomics_network, https://doi.org/10.17616/R3FS95 http://www.sgn.cornell.edu/ SCR_004933 SGN ref, Sol Genomics Network 2026-08-04 09:41:15 993
Kismeth
 
Resource Report
Resource Website
50+ mentions
Kismeth (RRID:SCR_005444) Kismeth data analysis service, analysis service resource, production service resource, service resource A web-based tool for bisulfite sequencing analysis that was designed to be used with plants, since it considers potential cytosine methylation in any sequence context (CG, CHG, and CHH). It provides a tool for the design of bisulfite primers as well as several tools for the analysis of the bisulfite sequencing results. Kismeth is not limited to data from plants, as it can be used with data from any species. plant, methylation, bisulfite sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
PMID:18786255 Free for academic use, Contact for commercial use biotools:kismeth, OMICS_00602 https://bio.tools/kismeth SCR_005444 2026-08-04 09:41:22 53
ProfCom - Profiling of complex functionality
 
Resource Report
Resource Website
1+ mentions
ProfCom - Profiling of complex functionality (RRID:SCR_005797) ProfCom data analysis service, analysis service resource, production service resource, service resource Profiling of Complex Functionality (ProfCom) is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of complex function. A complex function is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. Platform: Online tool gene, function, profile, gene ontology, complex function, statistical analysis, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: Institute of Bioinformatics and Systems Biology; Neuherberg; Germany
DFG PMID:16959266 Free for academic use biotools:profcom, nlx_149276 https://bio.tools/profcom SCR_005797 Profiling of Complex Functionality, Profiling of Complex Functionality (ProfCom) 2026-08-04 09:41:27 4
SerbGO
 
Resource Report
Resource Website
SerbGO (RRID:SCR_005798) SerbGO data analysis service, analysis service resource, production service resource, service resource SerbGO is a web-based tool intended to assist researchers determine which microarray tools for gene expression analysis which make use of the GO ontologies are best suited to their projects. SerbGO is a bidirectional application. The user can ask for some features by checking on the Query Form to get the appropriate tools for their interests. The user can also compare tools to check which features are implemented in each one. Platform: Online tool microarray, gene expression, statistical analysis, gene ontology, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Barcelona; Barcelona; Spain
PMID:18480123 Free for academic use nlx_149286, biotools:serbgo https://bio.tools/serbgo SCR_005798 SerbGO - Searching the best GO Tool 2026-08-04 09:41:26 0
GoPubMed
 
Resource Report
Resource Website
10+ mentions
GoPubMed (RRID:SCR_005823) GoPubMed database, data or information resource, service resource A web server which allows users to explore PubMed search results with the Gene Ontology, a hierarchically structured vocabulary for molecular biology. GoPubMed submits a user''''s keywords to PubMed, retrieves the abstracts, detects Gene Ontology terms in the abstracts, displays the subset of Gene Ontology relevant to the original query, and allows the user to browse through the ontology displaying associated papers and their GO annotation. Platform: Online tool other analysis, literature curation and exploration, gene ontology, pubmed, literature, bio.tools is listed by: OMICtools
is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: PubMed
has parent organization: Biotechnology Center of the TU Dresden
European Union IST-2004-506779 PMID:15980585 Free for academic use biotools:gopubmed, nlx_149328, OMICS_01183 https://bio.tools/gopubmed SCR_005823 2026-08-04 09:41:26 29
Expression Profiler
 
Resource Report
Resource Website
1+ mentions
Expression Profiler (RRID:SCR_005821) Expression Profiler data analysis service, analysis service resource, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The EP:GO browser is built into EBI's Expression Profiler, a set of tools for clustering, analysis and visualization of gene expression and other genomic data. With it, you can search for GO terms and identify gene associations for a node, with or without associated subnodes, for the organism of your choice. other analysis, cluster, analysis, visualization, gene expression, genomic, gene ontology, gene association, microarray, protein-protein interaction, gene, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: European Bioinformatics Institute
European Union ;
Wellcome Trust ;
Estonian Science Foundation 5724;
Estonian Science Foundation 5722
PMID:15215431 THIS RESOURCE IS NO LONGER IN SERVICE biotools:expression_profiler, nlx_149323 https://bio.tools/expression_profiler SCR_005821 Expression Profiler at the EBI 2026-08-04 09:41:27 6
UniParc
 
Resource Report
Resource Website
50+ mentions
UniParc (RRID:SCR_005818) database, data or information resource Database that contains publicly available protein sequences with stable and unique identifiers (UPI) which are never removed, changed or reassigned. UniParc tracks sequence changes in the source databases and archives the history of all changes. Information other than protein sequence must be retrieved from the UniParc source databases using the database cross-references. protein sequence, database, public protein sequence, gold standard, upi, unique protein identifier, identifier, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: UniProt DAS
is related to: WormBase
is related to: FlyBase
is related to: Ensembl
is related to: RefSeq
has parent organization: UniProt
Public, Entries are available for download SCR_004769, nif-0000-03610, r3d100011519, biotools:uniparc, nlx_76940 https://bio.tools/uniparc, https://doi.org/10.17616/R3X33B SCR_005818 UniProt Archive 2026-08-04 09:41:27 87
DBETH - Database for Bacterial ExoToxins for Humans
 
Resource Report
Resource Website
1+ mentions
DBETH - Database for Bacterial ExoToxins for Humans (RRID:SCR_005908) DBETH database, data or information resource Database of Bacterial ExoToxins for Human is a database of sequences, structures, interaction networks and analytical results for 229 exotoxins, from 26 different human pathogenic bacterial genus. All toxins are classified into 24 different Toxin classes. The aim of DBETH is to provide a comprehensive database for human pathogenic bacterial exotoxins. DBETH also provides a platform to its users to identify potential exotoxin like sequences through Homology based as well as Non-homology based methods. In homology based approach the users can identify potential exotoxin like sequences either running BLASTp against the toxin sequences or by running HMMER against toxin domains identified by DBETH from human pathogenic bacterial exotoxins. In Non-homology based part DBETH uses a machine learning approach to identify potential exotoxins (Toxin Prediction by Support Vector Machine based approach). sequence, structure, interaction network, human, pathogen, bacterial genus, toxin, bacteria, exotoxin, homology, homolog, structure, sequence, domain, prediction, mechanism, activity, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: CSIR - Indian Institute of Chemical Biology; Kolkata; India
Council of Scientific and Industrial Research; New Delhi; India PMID:22102573 nlx_149481, biotools:dbeth https://bio.tools/dbeth SCR_005908 Database for Bacterial ExoToxins for Humans 2026-08-04 09:41:28 2
TRANSFAC
 
Resource Report
Resource Website
100+ mentions
TRANSFAC (RRID:SCR_005620) TRANSFAC database, data or information resource Manually curated database of eukaryotic transcription factors, their genomic binding sites and DNA binding profiles. Used to predict potential transcription factor binding sites. Curated, eucaryotic, transcription, factor, genomic, binding, site, sequence, regulated, gene, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: Gene Regulation Databases
is related to: TRANSPATH
is related to: Babelomics
is related to: GeneTrail
works with: rVista
European Commission ;
German Ministry of Education and Research
PMID:12520026 Free, Freely available biotools:transfac, nif-0000-03576 http://www.biobase-international.com/pages/index.php?id=transfac, http://gene-regulation.com/pub/databases.html, https://bio.tools/transfac SCR_005620 2026-08-04 09:41:23 261
IndelFR - Indel Flanking Region Database
 
Resource Report
Resource Website
1+ mentions
IndelFR - Indel Flanking Region Database (RRID:SCR_006050) IndelFR database, data or information resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. Indel Flanking Region Database is an online resource for indels and the flanking regions of proteins in SCOP superfamilies, including amino acid sequences, lengths, locations, secondary structure constitutions, hydrophilicity / hydrophobicity, domain information, 3D structures and so on. It aims at providing a comprehensive dataset for analyzing the qualities of amino acid insertion/deletions(indels), substitutions and the relationship between them. The indels were obtained through the pairwise alignment of homologous structures in SCOP superfamilies. The IndelFR database contains 2,925,017 indels with flanking regions extracted from 373,402 structural alignment pairs of 12,573 non-redundant domains from 1053 superfamilies. IndelFR has already been used for molecular evolution studies and may help to promote future functional studies of indels and their flanking regions. indel, flanking region, protein, structural domain, domain, protein superfamily, protein structure, insertion/deletion, insertion, deletion, protein sequence, sequence, structure, protein domain, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: SCOP: Structural Classification of Proteins
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Shandong University; Shandong; China
Independent Innovation Foundation of Shandong University 2009JC006;
National Natural Science Foundation of China 30970092;
National Natural Science Foundation of China 61070017;
Scientific Research Reward Fund for excellent Young and Middle-Aged scientists in Shandong Province 20090451326
PMID:22127860 THIS RESOURCE IS NO LONGER IN SERVICE biotools:indelfr, nlx_151448 https://bio.tools/indelfr SCR_006050 IndelFR: Indel Flanking Region Database, Indel Flanking Region Database 2026-08-04 09:41:29 2
SNPedia
 
Resource Report
Resource Website
50+ mentions
SNPedia (RRID:SCR_006125) SNPedia database, data or information resource Wiki investigating human genetics including information about the effects of variations in DNA, citing peer-reviewed scientific publications. It is used by Promethease to analyze and help explain your DNA. It is based on a wiki model in order to foster communication about genetic variation and to allow interested community members to help it evolve to become ever more relevant. As the cost of genotyping (and especially of fully determining your own genomic sequence) continues to drop, we''''ll all want to know more - a lot more - about the meaning of these DNA variations and SNPedia will be here to help. SNPedia has been launched to help realize the potential of the Human Genome Project to connect to our daily lives and well-being. For more information see the Wikipedia page, http://en.wikipedia.org/wiki/SNPedia * Download URL: http://www.SNPedia.com/index.php/Bulk * Web Service URL: http://bots.SNPedia.com/api.php dna, genetics, gene, genome, genoset, genotype, medicine, medical condition, genetic variation, dna, genetic variation, genomics, single nucleotide polymorphism, medical association, phenotypic association, genealogical association, variation, genome annotation, phenotype, web service, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
PMID:22140107 Creative Commons Attribution-NonCommercial-ShareAlike License, v3 biotools:snpedia, grid.465250.0, nlx_151604 https://ror.org/0253rdk33, https://bio.tools/snpedia SCR_006125 2026-08-04 09:41:30 62
RNA CoSSMos
 
Resource Report
Resource Website
1+ mentions
RNA CoSSMos (RRID:SCR_006120) RNA CoSSMos database, data or information resource Database to search through the nucleic acid structures from the Protein Data Bank and examine structural motifs, including (a)symmetric internal loops, bulge loops, and hairpin loops. They have compiled over 2,000 three-dimensional structures, which can now be searched using different parameters, including PDB information, experimental technique, sequence, and motif type. RNA secondary structure is important for designing therapeutics, understanding protein-RNA binding and predicting tertiary structure of RNA. Several databases and downloadable programs exist that specialize in the three-dimensional (3D) structure of RNA, but none focus specifically on secondary structural motifs such as internal, bulge and hairpin loops. To create the RNA CoSSMos database, 2156 Protein Data Bank (PDB) files were searched for internal, bulge and hairpin loops, and each loop''''s structural information, including sugar pucker, glycosidic linkage, hydrogen bonding patterns and stacking interactions, was included in the database. False positives were defined, identified and reclassified or omitted from the database to ensure the most accurate results possible. Users can search via general PDB information, experimental parameters, sequence and specific motif and by specific structural parameters in the subquery page after the initial search. Returned results for each search can be viewed individually or a complete set can be downloaded into a spreadsheet to allow for easy comparison. The RNA CoSSMos database is updated weekly. secondary structure motif, rna, three-dimensional structure, internal loop, bulge loop, hairpin loop, motif, nucleic acid, structure, secondary structure, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Saint Louis University; Missouri; USA
NIGMS 1R15GM085699-01A1 PMID:22127861 Freely accessible, Acknowledgement requested nlx_151597, biotools:rna_cossmos https://bio.tools/rna_cossmos SCR_006120 Znosko Lab RNA Characterization of Secondary Structure Motifs (RNA CoSSMos) database, Znosko Lab CoSSMos Database, RNA Characterization of Secondary Structure Motifs (RNA CoSSMos), RNA CoSSMos Database, RNA CoSSMos - Characterization of Secondary Structure Motifs, RNA Characterization of Secondary Structure Motifs 2026-08-04 09:41:31 1
NRG-CING
 
Resource Report
Resource Website
1+ mentions
NRG-CING (RRID:SCR_006079) NRG-CING database, data or information resource NRG-CING presents a complete validation report for all 9,000+ wwPDB NMR entries including remediated experimental data such as chemical shifts from BMRB and restraints from NRG . These CING reports are compiled from internal analyses and those by CCPN, DSSP, PROCHECK-NMR/Aqua, ShiftX, Talos+, Vasco, Wattos, and WHAT_CHECK. The NRG-CING website is a collection of CING reports that has been pre-calculated for all PDB files solved by NMR. (See website for more information on CING.) In case the underlying experimental data is available, these have been cleaned up and made syntactically and semantically correct and homogeneous. For many macromolecular NMR ensembles from the Protein Data Bank (PDB) the experiment-based restraint lists used in the structure calculation are accessible, while other experimental data, mainly chemical shift values, are often available from the BioMagResBank. Assessment of the quality of the structural result is paramount to their usage and a combined, integrated repository of both input data and structural results greatly facilitates such an analysis. In addition, the accuracy and precision of the coordinates in these macromolecular NMR ensembles can be improved by recalculations using the available experimental data and present-day software with improved protocols and force fields. Such efforts, however, generally fail on over half of all deposited structures due to the syntactic and semantic heterogeneity of the data and the wide variety of formats used for their deposition. We have combined the cleaned-up restraints information from the NMR Restraints Grid (NRG) database with available chemical shifts from the BioMagResBank in the weekly updated NRG-CING database. Eleven programs, in addition to CING itself, have been included in the NRG-CING production pipeline to arrive at validation reports that list for each entry the potential inconsistencies between the coordinates and the available restraint and chemical shift data. The longitudinal validation of this data yielded a set of indicators that can be used to judge the quality of every macromolecular structure solved with NMR. The cleaned up NMR experimental datasets and the validation reports are freely available. macromolecular structure, nmr, macromolecule, restraint, chemical shift, validation report, validation, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Worldwide Protein Data Bank (wwPDB)
is related to: NMR Restraints Grid
is related to: Biological Magnetic Resonance Data Bank (BMRB)
has parent organization: Radboud University; Nijmegen; The Netherlands
Netherlands Organization for Scientific Research (NWO) 700.55.443;
Netherlands Bioinformatics Centre (NBIC) ;
EU FP6 LSHG-CT-2005-018988;
EU FP6 LHSG-CT-2004-512092;
EU FP7 261572;
Brussels Institute for Research and Innovation BB2B 2010-1-12;
NLM LM05799
PMID:22139937 Free nlx_151486, biotools:nrg-cing https://bio.tools/nrg-cing SCR_006079 2026-08-04 09:41:30 1

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