Tools   Select Another Resource Report Type

https://openrefine.org/

Open source software Java tool for working with data. Used for loading data, cleaning up data, transforming data from one format into another and extending it with web services and external data.

Proper citation: OpenRefine (RRID:SCR_021305) Copy   

•   Source: SciCrunch Registry

https://hdmf.readthedocs.io/

Open source software Python package for working with hierarchical data. Provides APIs for specifying data models, reading and writing data to different storage backends, and representing data with Python object.Used for working with standardizing, reading, and writing hierarchical object data.

Proper citation: Hierarchical Data Modeling Framework (RRID:SCR_021303) Copy   

•   Source: SciCrunch Registry

https://github.com/taborlab/FlowCal

Open source software tool for automatically converting flow cytometry data from arbitrary to calibrated units. Can be run using intuitive Microsoft Excel interface, or customizable Python scripts. Software accepts Flow Cytometry Standard (FCS) files as inputs and is compatible with different calibration particles, fluorescent probes, and cell types. Automatically gates data, calculates common statistics, and produces plots.

Proper citation: FlowCal (RRID:SCR_018140) Copy   

•   Source: SciCrunch Registry

https://cometbio.org/

Software tool to quantify comet parameters while studying DNA strand breaks. Automated tool for comet assay image analysis.

Proper citation: OpenComet (RRID:SCR_021826) Copy   

•   Source: SciCrunch Registry

https://github.com/berenslab/mini-atlas

Phenotypic variation of transcriptomic cell types in mouse motor cortex.Repository contains analysis code and preprocessed data.Data includes exonic and intronic gene counts, extracted electrophysiological features, extracted morphological features and z-profiles. Datasets with recorded at room temperature and recorded at physiological temperature.

Proper citation: BarensLab Mini-Atlas (RRID:SCR_021115) Copy   

•   Source: SciCrunch Registry

https://rubygems.org/gems/viral_seq

Ruby Gem with bioinformatics tools for processing viral NGS data. Specifically for Primer-ID sequencing and HIV drug resistance analysis.

Proper citation: viral_seq (RRID:SCR_018515) Copy   

•   Source: SciCrunch Registry

http://www.nitrc.org/projects/arts/

Software tool as automated biomarker that outputs score linked to likelihood person sufferring from arteriolosclerosis based on brain MRI data and basic demographic information. MRI data processing pipeline and classifier are packaged into software container.Users do not need to perform any image processing, and are only required to install Singularity to run ARTS.

Proper citation: ARTS biomarker (RRID:SCR_019288) Copy   

•   Source: SciCrunch Registry

https://github.com/berenslab/EphysExtraction

Software tool as code to extract electrophysiological parameters of neurons. Code is continuously being updated to handle more kinds of voltage traces and extract different kinds of features.

Proper citation: EphysExtraction (RRID:SCR_018193) Copy   

•   Source: SciCrunch Registry

https://ibest.github.io/HTStream/

Software tool as quality control and processing pipeline for High Throughput Sequencing data. Uses tab delimited fastq format that allows for streaming from application to application. Interoperable with other standard Linux tools., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: HTStream (RRID:SCR_018354) Copy   

•   Source: SciCrunch Registry

https://www.utsouthwestern.edu/labs/danuser/software/

Software package as quantitative image analysis software for measurement of microtubule dynamics. MATLAB software for tracking full dynamics of microtubules based on plusTIP marker live cell image sequences.

Proper citation: plusTipTracker (RRID:SCR_021890) Copy   

•   Source: SciCrunch Registry

https://github.com/ttrogers/DecodingDynamic

Data, code, and notebooks for replicating analyses reported in Rogers et al., Evidence for deep, distributed and dynamic semantic code in human ventral anterior temporal cortex.

Proper citation: DecodingDynamic (RRID:SCR_021099) Copy   

•   Source: SciCrunch Registry

https://github.com/muriloHoracio/TERL

Software tool for classification of transposable elements by convolutional neural networks. Preprocesses and transforms one dimensional sequences into two dimensional space data, image like data of sequences, and apply it to deep convolutional neural networks.

Proper citation: TERL (RRID:SCR_022064) Copy   

•   Source: SciCrunch Registry

https://github.com/ComparativeGenomicsToolkit/hal/tree/master/synteny

Software tool as conserved synteny block construction method for multiple whole-genome alignments. Implementation of DAG-based for reconstruction of synteny blocks from genome alignment.

Proper citation: halSynteny (RRID:SCR_018127) Copy   

•   Source: SciCrunch Registry

https://broadinstitute.github.io/warp/docs/Pipelines/Smart-seq2_Single_Nucleus_Multi_Sample_Pipeline/README

The Smart-seq2 Single Nucleus Multi-Sample (Multi-snSS2) pipeline was developed in collaboration with the BRAIN Initiative Cell Census Network (BICCN) to process single-nucleus RNAseq (snRNAseq) data generated by Smart-seq2 assays.

Proper citation: Smart-seq2 Multi-Sample Pipeline (RRID:SCR_018920) Copy   

•   Source: SciCrunch Registry

https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/balbes/balbes_layout.html

Software system for solving protein structures using x-ray crystallographic data. Automatic molecular replacement pipeline for molecular replacement in CCP4. Integrates into one system all components necessary for solving crystal structure by Molecular Replacement. System is automated so that it needs no user intervention when running combination of jobs such as model searching, molecular replacement and refinement.

Proper citation: BALBES (RRID:SCR_018763) Copy   

•   Source: SciCrunch Registry

http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/genomic_curated_CDF.asp

Brainarray custom CDFs for processing raw Affymetrix data. Used to map probe to probesets. Oligonucleotide probes on GeneChips are reorganized based on latest genome and transcriptome information.

Proper citation: CustomCDF (RRID:SCR_018527) Copy   

•   Source: SciCrunch Registry

https://github.com/NeLy-EPFL/DeepFly3D

Software tool as PyTorch and PyQT5 implementation of 2D-3D tethered Drosophila pose estimation. Image annotation tool used for pose estimation and appendage tracking. Provides interface for pose estimation and to permit further correction of 2D pose estimates, which are automatically converted to 3D pose.

Proper citation: DeepFly3D (RRID:SCR_021402) Copy   

•   Source: SciCrunch Registry

https://www.cs.bham.ac.uk/~ibs/imzMLConverter/

Software tool for generating imzML. Allows conversion to imzML mass spectrometry imaging standard utilising mzML mass spectrometry standard as intermediary format.

Proper citation: imzMLConverter (RRID:SCR_021642) Copy   

•   Source: SciCrunch Registry

https://www.biocompare.com/19333-Image-Analysis-Software-Image-Processing-Software/4378970-Definiens-Tissue-Studio/

Software to detect regions of interests and distinguishes cells and sub-cellular objects within these target regions from immunohistochemistry specimen. Used for digital pathology image analysis.

Proper citation: Tissue Studio (RRID:SCR_023001) Copy   

•   Source: SciCrunch Registry

https://www.nitrc.org/projects/qcalign

Software tool to detect regions that are affected by tissue damage, labelling defects, artifacts or errors in image acquisition, regions that are poorly registered, or where registration cannot be verified. Makes it easier for the user to explore the atlas hierarchy and decide on customized hierarchy level for investigation. QCAlign was developed to support QUINT workflow which supports spatial analysis of labelling in series of brain sections from mouse and rat based on registration to reference atlas.

Proper citation: QCAlign (RRID:SCR_023088) Copy   

•   Source: SciCrunch Registry