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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Clinical research platform and longitudinal observational study for Huntington’s Disease families intended to accelerate progress towards therapeutics. Collaboration between Huntington’s disease families, clinicians, and researchers to accelerate progress toward effective treatments.
Proper citation: Enroll-HD (RRID:SCR_023300) Copy
https://rostlab.org/owiki/index.php/PROFisis
Software tool that identifies interacting residues from sequence alone. Developed using transient protein�protein interfaces from complexes of experimentally known 3D structures.
Proper citation: PROFisis (RRID:SCR_024179) Copy
http://contra.stanford.edu/contrafold/
Software novel secondary structure prediction method based on conditional log-linear models, a flexible class of probabilistic models which generalize upon SCFGs by using discriminative training and feature-rich scoring. Used for sequence prediction.
Proper citation: CONTRAfold (RRID:SCR_023994) Copy
https://rostlab.org/owiki/index.php/Metastudent
Software tool to predict gene ontology terms for protein sequences through homology.
Proper citation: Metastudent (RRID:SCR_024110) Copy
Core facility for cystic fibrosis mouse strains. Services include mouse production from current strains and creation of new strains, mouse strain maintenance, tissue acquisition, genotyping and treatment of mice with IACUC approved drugs to test potential therapies. Maintains centralized database that contains breeding history, phenotypes observed and experimental records of various CF mouse strains.
Proper citation: Case Western Reserve University Cystic Fibrosis Mouse Models Core (RRID:SCR_017238) Copy
Software tool for practical self assessment and reporting method for clinical research studies, to capture key information about data acquisition and quality control measures. Linked to dataset so that potential research collaborators can determine if data meets their needs and expectations.
Proper citation: DAQCORD (RRID:SCR_017395) Copy
https://haddock.science.uu.nl/dna/dna.php
DNA structure modelling server. Web server for generating custom 3D structural models of DNA with control over local and global conformation.
Proper citation: 3D DART (RRID:SCR_017588) Copy
https://lifesciencedb.jp/bp3d/
Web application that enables users to build and publish own custom manikins. Used to build three dimensional model of human body using parts registered in BodyParts3D. Server returns image of assembled 3D model as still image, rotating animation, interactive image, etc. Each part can be downloaded as polygon mesh file that can be used with 3D printer.
Proper citation: Anatomography (RRID:SCR_018147) Copy
Portal dedicated to funding lung cancer research by LUNGevity Foundation. Supports patient focused research and convene multi stakeholder meetings to streamline research process and accelerate progress to patients. Seeks to empower patients to be active decision makers in their treatment process through educational resources, online peer-to-peer support, and in-person survivorship programs.
Proper citation: LUNGevity (RRID:SCR_018570) Copy
https://crowdfightcovid19.org/
Initiative from scientific community to put all available resources including highly skilled scientists at service of fight against COVID-19.
Proper citation: Crowdfight COVID-19 (RRID:SCR_018340) Copy
Web tool for graphical illustrations for biological systems by BioRender. Used for articles and presentations. Collection of pre made icons and templates from life science fields for scientific illustrations. Customized icons possible on request.
Proper citation: Biorender (RRID:SCR_018361) Copy
http://www.sph.umich.edu/csg/abecasis/QTDT/
How is association mapping going to help me find genes? During the past decade, the genes for a large number of rare mendelian traits have been identified. However, traditional linkage analyses lack power and precision when applied to complex disease. Association mapping, which compares the effects of different chromosomal variants, may be more successful at identifying genes of small effect. How does QTDT help association mapping? Association mapping can produce misleading results when the study population is not homogeneous, but includes individuals with different genetic backgrounds. Family based association tests, commonly referred to as TDTs (Transmission Disequilibrium Tests), do not produce misleading results in these circumstances. QTDT can use all the information in a pedigree to construct powerful tests of association that are robust in the presence of stratification. What does the Q stant for ? Q stands for Quantitative. Quantitative traits provide effective descriptions of many complex diseases, including asthma. For many of these conditions, all or nothing definitions of disease are arbitrary and unsatisfactory. QTDT incorporates variance components methodology in the analysis of family data and includes exact estimation of p-values for analysis of small samples and non-normal data. The QTDT abbreviation (for Quantitative Transmission Disequilibrium Tests) was first used by David Allison in his 1997 paper. This research was supported in part by the intramural program of the National Eye Institute and by National Institutes of Health Grants EY016862, EY007758, EY09859, EY012118, P30-EY014801, EY-014458, EY014467, HL084729, and HG002651, by the Foundation Fighting Blindness, the Macula Vision Research Foundation, the American Health Assistance Foundation, Research to Prevent Blindness, the Pew Charitable Trusts, the Mayo Clinic Foundation, the Casey Macular Degeneration Center Fund, the Marion W. and Edward F. Knight AMD Fund, the Harold and Pauline Price Foundation, National Genotyping Centre of Spain, and the Elmer and Sylvia Sramek Foundation. The Center for Inherited Disease Research, fully funded through a federal contract (HHSN268200782096C) from National Institutes of Health to
Proper citation: Linkage Disequilibrium Analyses for Quantitative and Discrete Traits (RRID:SCR_013365) Copy
http://www.scienceexchange.com/facilities/barts-and-the-london-school-of-medicine-and-dentistry
Barts and The London offers international levels of excellence in research and teaching while serving a population of unrivalled diversity. Through partnership with our linked trusts, notably Barts and The London NHS Trust, and our associated University Hospital Trusts _������������_ Homerton, Newham, Whipps Cross and Queen''''s (Romford) the School''''s research and teaching is informed by an exceptionally wide ranging and stimulating clinical environment.
Proper citation: Barts and The London School of Medicine and Dentistry Labs and Facilities (RRID:SCR_012710) Copy
http://www.scienceexchange.com/facilities/michigan-state-university
An Portal, Core facility
Proper citation: Michigan State University Labs and Facilities (RRID:SCR_012252) Copy
http://phaffcollection.ucdavis.edu/
Collection of wild yeast in the world. Academic and industrial resarchers utilize this collection for a variety of research and applications, including pigments, enzymes, food ingredients, and hosts for protein expression. Provides contract screening and strain selection services.
Proper citation: Phaff Yeast Culture Collection (RRID:SCR_016781) Copy
http://cmmt.ubc.ca/facilities-services/mouse-animal-production/
Supplier of mice for research purposes. The service is run by Dr. Elizabeth M. Simpson, Ph.D. and is affiliated with her lab.
Proper citation: CMMT Mouse Animal Production Service (RRID:SCR_016403) Copy
https://doi.org/10.7910/DVN/XD1A6B
Portal for cross sectional study where population based sample of adult cancer patients were recruited for mailed survey (with telephone follow-up of non-responders) to evaluate equivalence of PROMIS measures across socio-demographic and clinical sub-groups.
Proper citation: PROMIS 2 MY Health (RRID:SCR_021215) Copy
https://github.com/HeardLibrary/linked-data/tree/master/vanderbot
Software Python tool as Vanderbilt University curation tool.Used for exporting public profiles of university faculty from Vanderbilt University database into Wikidata.Used to create or update items in Wikidata using data from CSV spreadsheet data.
Proper citation: VanderBot (RRID:SCR_021298) Copy
https://emea.support.illumina.com/sequencing/sequencing_software/experiment_manager/downloads.html
Software to create and edit sample sheet in order to perform next generation sequencing on Illumina paltforms. Used for MiniSeq, MiSeq, NextSeq 500/550, HiSeq, and NovaSeq 6000 Systems.
Proper citation: Illumina Experiment Manager (RRID:SCR_021202) Copy
Software tool used to create summary of findings tables for cochrane systematic reviews. Web application to create, manage and share summaries of research evidence called Evidence Profiles and Summary of Findings Tables.
Proper citation: GRADEpro (RRID:SCR_021308) Copy
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