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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://mmoc.med.umich.edu/CoreHumanPhenotyping.php
Core that aims to enhance and expand the research capabilities of investigators performing clinical and translational studies related to nutritional interventions, obesity, or obesity-related disorders in humans. Its services include standardized nutritional assessments and physiological testing of human subjects, researcher assistance in conducting dietary, behavioral, and/or exercise intervention in human subjects, and training in techniques or the assistance in development of new techniques and technologies for the metabolic and neurobehavioral assessment of humans.
Proper citation: University of Michigan Nutrition and Obesity Research Center Human Phenotyping Core (RRID:SCR_015460) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=47
Core whose services include in vivo physiological assessments encompassing glucose homeostasis (glucose tolerance, insulin tolerance, hyperinsulinemic/euglycemic clamps), energy homeostasis (indirect calorimetry by CLAMS, dietary challenge), ultradian hormone secretion (Culex platform for serial biological fluid sampling from unrestrained mice), behavioral measurements (locomotor activity, meal pattern analysis, operant conditioning) and generation of bariatric surgery models.
Proper citation: MMPC-University of Michigan Medical School Metabolism Bariatric Surgery and Behavior Core (RRID:SCR_015354) Copy
http://mmpc.ucdavis.edu/core.php?coreID=29
Core that provides phenotyping services for the assessment of endocrine function and metabolic pathways in mouse models of obesity, diabetes, and related metabolic diseases including dyslipidemia and fatty liver disease.
Proper citation: MMPC-University of California Davis Endocrinology and Metabolism Core (RRID:SCR_015359) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=27
Core that provides importation/exportation, colony management, customized mouse models, rederivation and creation of genetically-modified mutant mice (e.g. CRISPR), and re-animation of a variety of models cryopreserved within the KOMP or MMRRC repositories. It also provides ancillary services and procedures, including blood sampling for in vivo testing for glucose tolerance tests and insulin tolerance tests.
Proper citation: MMPC-University of California Davis Animal Care Surgery and Pathology Core (RRID:SCR_015356) Copy
http://zfrhmaps.tch.harvard.edu/cemh/CoreA.htm
Core facility which generates genetically modified mice with gene knockout/knockin lines for analysis gene function in hematopoiesis.
Proper citation: Boston Children's Hospital Center of Excellence in Molecular Hematology Mouse Embryonic Stem(ES) Cell and Gene Targeting Core (RRID:SCR_015350) Copy
http://norc.pbrc.edu/animal_core.asp
Core that is comprised of the Animal Models Subcore and Animal Phenotyping Subcore. The former provides expertise and services for design and construction of transgenes, ES cell transfection and screening, pronuclear injection, and cryopreservation. The latter provides expertise and services for metabolism, physical activity, body composition, and behavioral research.
Proper citation: Pennington Biomedical Research Center Nutrition and Obesity Research Center Animal Models and Phenotyping Core (RRID:SCR_015443) Copy
http://norc.pbrc.edu/human_core.asp
Core that provides users with expertise and phenotyping services for different stages in life. It specifically provides services for obesity research, unique populations (pregnant women, children, infants, etc.), and clinical and translational studies through their Energy Balance subcore and Behavioral subcore.
Proper citation: Pennington Biomedical Research Center Nutrition and Obesity Research Center Human Phenotyping Core (RRID:SCR_015440) Copy
http://norc.pbrc.edu/molecular_core.asp
Core that includes a genomics subcore that provides services in genomics such as Sanger DNA sequencing and fragment analysis service, microarray analysis service, quantitative PCR, robotic pipetting for quantitative PCR and custom pipetting projects, and software analysis solutions. The Cell Biology &and Bioimaging subcore provides histology and specipmen preparation, imaging, and flow cytometry/cell sorting.
Proper citation: Pennington Biomedical Research Center Nutrition and Obesity Research Center Molecular Mechanisms Core (RRID:SCR_015441) Copy
http://sph.unc.edu/norc/clinical-program/
Core for nutrition researchers that consists of two subcores: the Human Research Core and the Nutrition Research Kitchen and Metabolism Core. The Human Research Core provides human metabolism and body composition assessments, clinical laboratory and support services, and preparation and delivery of precisely designed meals for study participants. The Nutrition Research Kitchen and Metabolism Core offers nutrition research assistance to complement clinical studies.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Clinical Nutrition Research Facilitation Program (RRID:SCR_015444) Copy
http://www.norc.uab.edu/corefacilities/biostatistics
Core which provides services and expertise in the design, management and analysis of nutrition-related research projects. Its services include coordination and management of statistical activities within the Core, statistical consultation on study design, research proposal development and manuscript submission, and statistical analysis.
Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Biostatistics Core (RRID:SCR_015449) Copy
Core that is responsible for all statistical, data management and epidemiological aspects of studies in the Mayo Clinic O'Brien Urology Research Center. Its services include consultation to project investigators regarding study design, data analysis and interpretation of results, maintanence of the Olmsted County kidney stone database, and development of additional linkable databases and quality control procedures.
Proper citation: Mayo Clinic O'Brien Urology Center Biostatistics and Epidemiology Core (RRID:SCR_015452) Copy
http://mmoc.med.umich.edu/AnimalPhenotyping/
Core whose services include infrastructure to perform advanced, standardized, metabolic phenotyping of animal models of obesity or metabolic diseases that arise from dietary, genetic, pharmacologic or other perturbations. It also provides centralized equipment and services and aims to develop new techniques and acquire new technologies for rodent phenotyping.
Proper citation: University of Michigan Nutrition and Obesity Research Center Animal Phenotyping Core (RRID:SCR_015458) Copy
http://mmoc.med.umich.edu/CoreMolecularPhenotyping.php
Core that provides analytical tools to MMOC investigators to permit structural identification and quantification of metabolites as well as perform metabolic studies in in vitro systems. It also provides consultation and collaboration to apply metabolomics platforms in nutrition and obesity research.
Proper citation: University of Michigan Nutrition and Obesity Research Center Molecular Phenotyping Core (RRID:SCR_015456) Copy
http://norc.ucsf.edu/mouse-metabolism-and-imaging-core-b
Core that provides access to instrumentation used in metabolic studies. Instruments include a 12-chambered Comprehensive Lab Animal Monitoring System (CLAMS), an EchoMRI, and dual energy X-ray absorptiometry.
Proper citation: University of California San Francisco Nutrition and Obesity Research Center Mouse Metabolism and Imaging Core (RRID:SCR_015450) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/clinical-core
Core facility which aims to provide cystic fibrosis researchers with a biobank of archived biosamples collected during routine clinical visits and research-related visits. Biospecimens include normal and CF specimens including DNA, bronchoalveolar lavage fluid, whole blood, plasma, feces, urine, and bacterial isolates. It also aims to facilitate patient recruitment and enrollment in clinical trials.
Proper citation: University of Iowa Center for Gene Therapy Clinical Core (RRID:SCR_015415) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/pre-clinical-core
Core whose objectives include evaluation of pre-clinical drug candidates in vitro, pre-clinical drug candidates ex vivo, and pre-clinical drug candidates in vivo.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Pre-Clinical Core (RRID:SCR_015387) Copy
http://bnorc.org/cores/administrative.html
Core that provides administrative support and direction to all of the participating institutions and BNORC members. These services include financial management, payment requests, policy development and data management.
Proper citation: Boston Nutrition and Obesity Research Centers Administrative Core (RRID:SCR_015425) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/molecular-biology-core
Core facility that provides expertise, equipment, training, and reagents to serve the molecular biology needs for cystic fibrosis research.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Molecular Biology Core (RRID:SCR_015384) Copy
http://www.norch.org/center-cores/genomics-and-cell-biology-core/
Core that facilitates the application of genomics, bioinformatics, cell biology, and immunology techniques to nutrition and metabolic research.
Proper citation: Nutrition and Obesity Research Centers at Harvard Genomics and Cell Biology Core (RRID:SCR_015427) Copy
http://www.medschool.umaryland.edu/norc/Cores/Clinical--Translational-Research-CTR-Core/
Core that facilitates the conduct of clinical nutrition and obesity research. Its team of experts in nutrition, exercise physiology, body composition, metabolism and behavioral therapy aim to assist and train NORCH investigators in the skills necessary to conduct clinical nutrition and obesity research.
Proper citation: Mid-Atlantic Nutrition Obesity Research Center Clinical and Translational Research Core (RRID:SCR_015431) Copy
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