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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
primers4clades
 
Resource Report
Resource Website
1+ mentions
primers4clades (RRID:SCR_015714) web application, software resource Web application for the design of PCR primers for cross-species amplification of novel sequences from metagenomic DNA or from uncharacterized organisms belonging to user-specified phylogenetic lineages. It implements an extended CODEHOP strategy and evaluates thermodynamic properties of the oligonucleotide pairs. pcr primer, metagenomic dna, phylogenetic lineage, primer, clade, bio.tools is listed by: Debian
is listed by: bio.tools
DGAPA IN201806-2;
CONACyT-Mexico P1-60071;
CSIC 200720I038
PMID:19465390 Freely available, Free for academic use, Tutorial available biotools:primers4clades http://maya.ccg.unam.mx/primers4clades, https://bio.tools/primers4clades SCR_015714 2026-08-04 09:43:42 2
clustergrammer
 
Resource Report
Resource Website
10+ mentions
clustergrammer (RRID:SCR_015681) data visualization tool, software tool Clustergrammer is a web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable hierarchically clustered heatmaps. Clustergrammer enables intuitive exploration of high-dimensional data and has several optional biology-specific features. bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/sdata.2017.151 biotools:clustergrammer https://bio.tools/clustergrammer SCR_015681 2026-08-04 09:43:43 41
oligo
 
Resource Report
Resource Website
1000+ mentions
oligo (RRID:SCR_015729) data processing software, source code, data analysis software, software resource, software application Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files). oligonucleotide, microarray gene expression, r, oligonucleotide array, snp, gene expression, probe-level, affymetrix array, cel file, and nimblegen array, xys file, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
CAPES (Coordenação de Aprimoramento Pessoal de Nível Superior) ;
NCRR R01RR021967;
NHGRI P41HG004059
PMID:20688976 Free, Available for download, Runs on Mac OS, Runs on Windows biotools:oligo https://bio.tools/oligo SCR_015729 oligo package 2026-08-04 09:43:42 1749
BSVF
 
Resource Report
Resource Website
1+ mentions
BSVF (RRID:SCR_015727) BSVF data processing software, source code, data analysis software, software resource, sequence analysis software, software application Software code for bisulfite sequencing virus integration. This finder is for directional libraries only and does not support PBAT and indirectional libraries. virus integration, sequencing analysis, virus assembly, integration, bisulfite, bio.tools is listed by: bio.tools
is listed by: Debian
Open source biotools:bs-virus-finder https://bio.tools/bs-virus-finder SCR_015727 BSVF: Bisulfite Sequencing Virus integration Finder, Bisulfite Sequencing Virus integration Finder 2026-08-04 09:43:43 1
GenePattern Notebook
 
Resource Report
Resource Website
1+ mentions
GenePattern Notebook (RRID:SCR_015699) systems interoperability software, software resource, software application, web application, electronic laboratory notebook Interactive analysis notebook environment that streamlines genomics research by interleaving text, multimedia, and executable code into unified, sharable, reproducible “research narratives.” It integrates the dynamic capabilities of notebook systems with an investigator-focused, simple interface that provides access to hundreds of genomic tools without the need to write code. gene, genomics research, research narrative, notebook system, analysis notebook, bio.tools is listed by: bio.tools
is listed by: Debian
is affiliated with: GenePattern
NIGMS R01-GM074024;
NCI U24-CA194107
PMID:28822753 Open Source, Free, Available for download, Account required biotools:GenePattern_notebook https://bio.tools/GenePattern_notebook SCR_015699 GenePattern Notebook environment 2026-08-04 09:43:43 3
DISEASES
 
Resource Report
Resource Website
500+ mentions
DISEASES (RRID:SCR_015664) database, data or information resource Database that integrates evidence on disease-gene associations from automatic text mining, manually curated literature, cancer mutation data, and genome-wide association studies. It also assigns confidence scores that facilitate comparison of the different types and sources of evidence. disease, gene, disease-gene association, text-mining, , bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation Center for Protein Research NNF14CC0001;
European Union Seventh Framework Programme n259348
PMID:25484339 biotools:diseases https://bio.tools/diseases SCR_015664 2026-08-04 09:43:43 627
TISSUES
 
Resource Report
Resource Website
10+ mentions
TISSUES (RRID:SCR_015665) web application, software resource, database, data or information resource Database that integrates evidence on tissue expression from manually curated literature, proteomics and transcriptomics screens, and automatic text mining. It maps all evidence to common protein identifiers and Brenda Tissue Ontology terms, and further unifies it by assigning confidence scores that facilitate comparison of the different types and sources of evidence. tissue expression, proteomic, transcriptomic, text-mining, brenda tissue ontology, protein identifier, bio.tools uses: BRENDA Tissue and Enzyme Source Ontology
is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation NNF14CC0001;
NCI U54 CA189205-01;
CSIRO’s OCE Science Leader program
PMID:26157623 Freely available, Free, Available for download biotools:tissues https://bio.tools/tissues SCR_015665 TISSUES: Tissue Expression Database, Tissue Expression Database 2026-08-04 09:43:42 42
HISAT2
 
Resource Report
Resource Website
10000+ mentions
HISAT2 (RRID:SCR_015530) data processing software, source code, data analysis software, software resource, sequence analysis software, software application Graph-based alignment of next generation sequencing reads to a population of genomes. alignment program, mapping reads, population genomics, human genome, bio.tools is used by: Fcirc
is listed by: Debian
is listed by: bio.tools
is related to: TopHat
has parent organization: Johns Hopkins University; Maryland; USA
is required by: SL-quant
is hosted by: GitHub
NLM R01-LM06845;
NIGMS R01-GM083873;
NSF CCF-0347992
PMID:25751142
DOI:10.1038/s41587-019-0201-4
Available for download OMICS_07225, biotools:hisat2 https://github.com/infphilo/hisat2, https://bio.tools/hisat2, https://sources.debian.org/src/hisat2/ SCR_015530 HISAT 2026-08-04 09:43:41 17595
Avogadro
 
Resource Report
Resource Website
1000+ mentions
Avogadro (RRID:SCR_015983) data processing software, data analysis software, software resource, software application, data visualization software, software toolkit Software for semantic chemical editing, visualization, and analysis. It is designed for cross-platform use in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. semantic, optimization, crystallography, chemical, editor, visualization, analysis, molecular, modeling, drug, design, biomolecule, simulation, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
Engineering Research Development Center W912HZ-11-P-0019;
NSF DMR-1005413
PMID:22889332
DOI:10.1186/1758-2946-4-17
Open source, Free, Free to download OMICS_04967, biotools:avogadro http://avogadro.openmolecules.net/, https://github.com/avogadro, https://bio.tools/avogadro, https://sources.debian.org/src/axe-demultiplexer/ SCR_015983 2026-08-04 09:43:46 1965
Hybrid-denovo
 
Resource Report
Resource Website
1+ mentions
Hybrid-denovo (RRID:SCR_015866) data processing software, data analysis software, software resource, sequence analysis software, software application Software for a de novo OTU-picking pipeline integrating single- and paired-end 16S sequence tags. It is designed to take Illumina paired-end sequencing reads as input and output the OTU BIOM table, together with their representative sequences and a phylogenetic tree of OTUs. hybrid-denovo, 16S rRNA, microbiota pipeline, single-end, paired-end, illumina read, de novo, otu-picking pipeline, phylogenetic tree, python, bio.tools is listed by: bio.tools
is listed by: Debian
biotools:hybrid-denovo https://bio.tools/hybrid-denovo SCR_015866 2026-08-04 09:43:45 3
Bio-tradis
 
Resource Report
Resource Website
50+ mentions
Bio-tradis (RRID:SCR_015993) TraDIS:Transposon Directed Insertion Sequencing data processing software, data analysis software, software resource, sequence analysis software, software application, software toolkit Analysis software for the output from TraDIS (Transposon Directed Insertion Sequencing) analyses of dense transposon mutant libraries. The Bio-Tradis analysis pipeline is implemented as an extensible Perl library which can either be used as is, or as a basis for the development of more advanced analysis tools. software, tool, analysis, data, sequencing, insertion, transponson, direct, mutant, library, perl, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust WT098051;
Alexander von Humboldt Stiftung/Foundation ;
Medical Research Council G1100100/1
PMID:26794317
DOI:10.1093/bioinformatics/btw022
Free, Available for download, Freely available OMICS_11083, biotools:bio-tradis https://bio.tools/bio-tradis, https://sources.debian.org/src/bio-tradis/ SCR_015993 2026-08-04 09:43:46 51
NiftyPET
 
Resource Report
Resource Website
1+ mentions
NiftyPET (RRID:SCR_015873) data processing software, source code, software resource, software application, image analysis software, data visualization software, software toolkit Python software package that offers quantitative PET image reconstruction and analysis with high accuracy and precision. It is written in CUDA C and embedded in Python C extensions. python, cuda c, python c, pet, image reconstruction, image analysis, bio.tools uses: CMake
is listed by: Debian
is listed by: bio.tools
DOI:10.1007/s12021-017-9352-y Free, Available for download, Runs on Windows, Runs on Linux biotools:niftypet https://bio.tools/niftypet SCR_015873 2026-08-04 09:43:44 6
andi
 
Resource Report
Resource Website
10+ mentions
andi (RRID:SCR_015971) data processing software, alignment software, algorithm resource, software resource, software application, image analysis software Software tool for rapidly computing and estimating evolutionary distance between closely related genomes. Because andi does not compute full alignments it scales even up to thousands of bacterial genomes. algorithm, computing, estimate, analysis, genome, alignment, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Deutsche Forschungsgemeinschaft Pf672/3-1 PMID:25504847 Free, Freely available, Available for download OMICS_09287, biotools:andi https://bio.tools/andi, https://sources.debian.org/src/andi/ SCR_015971 2026-08-04 09:43:46 41
larvalign
 
Resource Report
Resource Website
1+ mentions
larvalign (RRID:SCR_015815) data processing software, data analysis software, data set, software resource, sequence analysis software, software application, software toolkit, data or information resource Software package including computational methods for aligning gene expression patterns from the larval brain of Drosophila melanogaster. Its method includes evaluation of the registration framework involved in template generation and mapping. drosophila melanogaster, computational method, gene expression, alignment, larval brain, larvae, template generation, mapping, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download biotools:larvalign https://bio.tools/larvalign SCR_015815 2026-08-04 09:43:45 1
TreeDyn
 
Resource Report
Resource Website
100+ mentions
TreeDyn (RRID:SCR_015946) data processing software, data visualization software, software application, software resource Visualization software that links unique leaf labels to lists of variables/values pairs of annotations (meta-information), independently of the tree topologies, remaining fully compatible with the basic newick format. These relationships are used by dynamic graphics operators, information visualization methods like Projection, Localization, Labelization, Reflection allowing an interaction from annotations to trees, from trees to annotations and from trees to trees through annotations., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. tree, variable, annotation, metainfo, newick, topology, graphic, operator, projection, localization, reflection, leaf, label, bio.tools is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:treedyn https://bio.tools/treedyn SCR_015946 2026-08-04 09:43:47 355
SC3
 
Resource Report
Resource Website
10+ mentions
SC3 (RRID:SCR_015953) data processing software, data analysis software, software resource, sequence analysis software, software application Software tool for the unsupervised clustering of cells from single cell RNA-Seq experiments. SC3 is capable of identifying subclones from the transcriptomes of neoplastic cells collected from patients. scRNA-seq, interactive, cluster, clustering, cell, single, rna, rnaseq, bio.tools is listed by: Debian
is listed by: bio.tools
Wellcome Trust 104710/Z/14/Z;
Belgian Network DYSCO ;
FRS-FNRS ;
Belgian State Science Policy Office ;
ARC (Action de Recherche Concerte) ;
Wallonia-Brussels Federation ;
EPSRC EP/N014529/1;
Sanger Institute ;
University of Edinburgh ;
Bloodwise 13003;
MRC ;
Kay Kendall Leukaemia Fund ;
Cambridge NIHR Biomedical Research Center ;
Cambridge Experimental Cancer Medicine Centre ;
Leukemia and Lymphoma Society of America 07037
PMID:28346451 Free, Available for download biotools:sc3 https://bio.tools/sc3 SCR_015953 SC3 package, Single-Cell Consensus Clustering 2026-08-04 09:43:46 20
Canu
 
Resource Report
Resource Website
1000+ mentions
Canu (RRID:SCR_015880) data processing software, data analysis software, software resource, sequence analysis software, software application Software for scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation. Canu is a fork of the Celera Assembler and is designed for high-noise single-molecule sequencing (such as the PacBio RS II/Sequel or Oxford Nanopore MinION). long-read, assembly, k-mer, weighting, repeat separation, adaptive, pacbio, single-molecule, sequencing, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Celera assembler
National Human Genome Research Institute ;
US Department of Homeland Security (DHS) HSHQDC-07-C-00020;
National Science Foundation NSF IOS-1237993
PMID:28298431
DOI:10.1101/071282
Free, Available for download biotools:canu, OMICS_14592 http://canu.readthedocs.io/en/latest/, https://bio.tools/canu, https://sources.debian.org/src/canu/ SCR_015880 2026-08-04 09:43:45 2255
Genesis
 
Resource Report
Resource Website
1000+ mentions
Genesis (RRID:SCR_015775) data processing software, data analysis software, software resource, software application, data visualization software Software for cluster analysis of microarray data. Genesis is a platform independent Java package of tools to simultaneously visualize and analyze a whole set of gene expression experiments. cluster analysis, microarray data, java, gene expression, visualization, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
PMID:11836235 Free for academic use, Free for non-profits, Available for download, Runs on Windows, Runs on Mac OS, Runs on Linux biotools:genesis_microarray https://bio.tools/genesis_microarray SCR_015775 Genesis: Cluster analysis of microarray data 2026-08-04 09:43:43 1018
Barrnap
 
Resource Report
Resource Website
500+ mentions
Barrnap (RRID:SCR_015995) data processing software, data analysis software, software resource, sequence analysis software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software to predict the location of ribosomal RNA genes in genomes. It supports bacteria, archaea, mitochondria, and eukaryotes. It takes FASTA DNA sequence as input, writes GFF3 as output, and supports multithreading., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. multithreading, fasta, sequencing, software, predict, location, ribosomal, gene, genome, RNA, prediction, bacteria, archaea, mitochondria, eukaryote, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE biotools:barrnap, OMICS_13988 https://github.com/tseemann/barrnap, https://bio.tools/barrnap, https://sources.debian.org/src/barrnap/ SCR_015995 Barrnap: Basic rapid ribosomal RNA predictor 2026-08-04 09:43:47 568
HyPhy
 
Resource Report
Resource Website
1000+ mentions
HyPhy (RRID:SCR_016162) data processing software, data analysis software, software resource, sequence analysis software, software application, software toolkit Open source software package for comparative sequence analysis using stochastic evolutionary models. Used for analysis of genetic sequence data in particular the inference of natural selection using techniques in phylogenetics, molecular evolution, and machine learning. analysis, genetic, sequence, multiply, alignment, rate, pattern, data, evolution, platform, python, r, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NSF DBI-0096033;
NSF DEB-9996118;
NIH R01 AI47745;
NIH U01 AI43638;
University of California Universitywide AIDS Research Program IS02-SD-701;
University of California ;
San Diego Center for AIDS Research/NIAID Developmental Award 2 P30 AI36214;
NIGMS R01
PMID:15509596 Free, Available for download, Freely available SCR_016271, biotools:HyPhy, OMICS_04235 https://sources.debian.org/src/hyphy-pt/, https://veg.github.io/hyphy-site/, https://github.com/veg/hyphy, https://bio.tools/HyPhy, SCR_016162 HyPhy:Hypothesis Testing using Phylogenies, Hyphy-pt 2026-08-04 09:43:49 1497

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