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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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GC/GCF Resource Report Resource Website 1+ mentions |
GC/GCF (RRID:SCR_009075) | software resource, software application | Software application where GC implements the genomic control models. GCF implements the basic Genomic Control approach, but adjusts the p-values for uncertainty in the estimated effect of substructure. This approach is preferable if a large number of tests will be evaluated because it provides a more accurrate assessment of the significance level for small p-values. (entry from Genetic Analysis Software) | gene, genetic, genomic, r, linux | is listed by: Genetic Analysis Software | nlx_154072, SCR_000846, nlx_154584 | SCR_009075 | R/GCF, R/GC, Genomic Control | 2026-08-12 10:49:54 | 1 | |||||||||
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Homeobox Genes DataBase Resource Report Resource Website 1+ mentions |
Homeobox Genes DataBase (RRID:SCR_007723) | HoxPro | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 11th,2023. The database HOX Pro contains information about organization, functions and evolution of gene ensembles, key roles in which play homeobox-genes. It is aimed at: 1. analysis and classification of regulatory and coding regions in diverse homeobox and related genes; 2. describing mutations and knock-outs of hox-genes, as well as hereditary diseases related to these genes; 3. graphical representation, comparisons and classification of hox-genes expression patterns and profiles (sea urchin blastula, Drosophila blastoderm and imaginal discs, vertebrate limbs, mammalian brain, human EC cells); 4. comparative analysis of organization of hox-based genetic networks the nematode Caenorhabditis elegans the sea urchins Strongylocentrotus purpuratus and other echinids, the fruit flies Drosophila melanogaster and D.virilis, the vertebrates chicken and mouse; 5. analysis of phylogeny and evolution of homeobox genes and clusters. | homeobox, homeobox-genes, hox genes | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-20854, SCR_008115, nif-0000-02982 | SCR_007723 | 2026-08-12 10:49:44 | 1 | |||||||||
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The Loom Resource Report Resource Website 1+ mentions |
The Loom (RRID:SCR_006877) | Loom | data or information resource, narrative resource, blog | The Loom is a blog about life, past and future. Written by DISCOVER contributing editor and columnist Carl Zimmer. Carl Zimmer writes about science regularly for the New York Times and magazines such as Discover, where he is a contributing editor and columnist. | has parent organization: Discover Magazine | nlx_83062 | SCR_006877 | 2026-08-12 10:49:33 | 1 | ||||||||||
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Sapienta Resource Report Resource Website 1+ mentions |
Sapienta (RRID:SCR_006993) | SAPIENTA | software application, software resource, source code | Software to help researchers process scientific papers faster and get the information they are interested in out of them. This is achieved by automating the recognition of core scientific concepts such as Motivation, Method, Result, Conclusion in papers and uses them to generate automatic summaries. This SAPIENTA tool adds additional functionality to the SAPIENT tool, an annotation tool implemented as a web application which enables experts to annotate scientific papers, sentence by sentence manually, according to the Core Scientific Concept (CSC) schema. | semantic mark up, semantic, annotation, annotation software | is listed by: FORCE11 | JISC | nlx_151311 | SCR_006993 | SAPIENTA - Automating the Semantic Annotation of Papers, Semantic Annotation of Papers: Interface & ENrichment Tool Automated | 2026-08-12 10:49:36 | 1 | |||||||
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GOstat Resource Report Resource Website 100+ mentions |
GOstat (RRID:SCR_008535) | GOstat | production service resource, data analysis service, analysis service resource, service resource | GOstat is a tool that allows you to find statistically overrepresented Gene Ontologies within a group of genes. The Gene-Ontology database (GO: http://www.geneontology.org) provides a useful tool to annotate and analyze the function of large numbers of genes. Modern experimental techniques, as e.g. DNA microarrays, often result in long lists of genes. To learn about the biology in this kind of data it is desirable to find functional annotation or Gene-Ontology groups which are highly represented in the data. This program (GOstat) should help in the analysis of such lists and will provide statistics about the GO terms contained in the data and sort the GO annotations giving the most representative GO terms first. Run GOstat: * Go to search form - Computes GO statistics of a list of genes selected from a microarray. * GOstat Display - You can store results from a previously run and view them here, either by uploading them as a file or putting them on a selected URL. * Upload Custom GO Annotations - This allows you to upload your own GO annotation database and use it with GOstat. Variants of GOstat: * Rank GOstat - Takes input from all genes on microarray instead of using a fixed cutoff and uses ranks using a Wilcoxon test or either ranks or pvalues to score GOs using Kolmogorov-Smirnov statistics. * Gene Abundance GOstats - Takes input from all genes on microarray and sums up the gene abundances for each GO to compute statistics. * Two list GOstat - Compares GO statistics in two independent lists of genes, not necessarily one of them being the complete list the other list is sampled from. Platform: Online tool, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | gene, gene ontology, annotation, statistical analysis, FASEB list |
is listed by: Gene Ontology Tools is related to: Gene Ontology has parent organization: Walter and Eliza Hall Institute of Medical Research; Victoria; Australia |
DFG | PMID:14962934 | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-30625 | SCR_008535 | 2026-08-12 10:49:47 | 159 | ||||||
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Pythonxy Resource Report Resource Website 10+ mentions |
Pythonxy (RRID:SCR_006903) | Python-xy, Python(x, y) | software development tool, software application, software resource, source code | Scientific and engineering development software for numerical computations, data analysis and data visualization based on Python programming language, Qt graphical user interfaces and Spyder interactive scientific development environment. Used to interpreted languages (such as MATLAB or IDL) or compiled languages (C/C++ or Fortran) to switch to Python. | program, language, python, computation, data analysis, data visualization, plugin | is related to: Spyder | Free, Available for download, Freely available | nlx_149232 | http://www.pythonxy.com, https://code.google.com/p/pythonxy/wiki/Welcome | SCR_006903 | pythonxy - Scientific-oriented Python Distribution based on Qt and Spyder, Python(x, y) - Scientific oriented Python Distribution based on Qt and Spyder | 2026-08-12 10:49:34 | 10 | ||||||
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IRESite Resource Report Resource Website 50+ mentions |
IRESite (RRID:SCR_007753) | data or information resource, database | Database of experimentally verified IRES structures. Presents information about experimentally studied Internal Ribosome Entry Site segments. | bio.tools, experimentally verified IRES structures, Internal Ribosome Entry Site segments, IRES structures, IRES segments |
is listed by: bio.tools is listed by: Debian has parent organization: Charles University; Prague; Czech Republic |
nif-0000-03047, nif-0000-03046, SCR_007754, biotools:iresite | https://bio.tools/iresite | http://ifr31w3.toulouse.inserm.fr/IRESdatabase/ | SCR_007753 | IRESdb, , IRESdb - the Internal Ribosome Entry Site database, Internal Ribosome Entry Site | 2026-08-12 10:49:44 | 52 | |||||||
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GeneTerm Linker Resource Report Resource Website 1+ mentions |
GeneTerm Linker (RRID:SCR_006385) | GTLinker | production service resource, data analysis service, analysis service resource, service resource | Web application that filters and links enriched output data identifying sets of associated genes and terms, producing metagroups of coherent biological significance. The method uses fuzzy reciprocal linkage between genes and terms to unravel their functional convergence and associations. It can also be accessed through its web service. | gene, functional annotation, function, functional metagroup, p-value, annotation, web service |
is listed by: OMICtools is related to: Gene Ontology is related to: KEGG is related to: InterPro has parent organization: Spanish National Research Council; Madrid; Spain |
PMID:21949701 | Acknowledgement requested | OMICS_02227 | SCR_006385 | GeneTerm Linker - post enrichment functional association by non-redundant reciprocal linkage | 2026-08-12 10:49:25 | 2 | ||||||
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Atlas of Genetics and Cytogenetics in Oncology and Haematology Resource Report Resource Website 10+ mentions |
Atlas of Genetics and Cytogenetics in Oncology and Haematology (RRID:SCR_007199) | data or information resource, atlas, database | Online journal and database devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases. Its aim is to cover the entire field under study and it presents concise and updated reviews (cards) or longer texts (deep insights) concerning topics in cancer research and genomics. | gene, cytogenetic, cancer, cancer research, genomic, online journal, bio.tools, FASEB list |
is listed by: Debian is listed by: bio.tools |
PMID:23161685 | Freely available, Available to the scientific community | nif-0000-30129, biotools:atlasgeneticsoncology | https://bio.tools/atlasgeneticsoncology | SCR_007199 | Genetics and Cytogenetics Atlas | 2026-08-12 10:49:35 | 43 | ||||||
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Exon Array Analyzer Resource Report Resource Website 1+ mentions |
Exon Array Analyzer (RRID:SCR_008684) | Exon Array Analyzer | production service resource, data analysis service, analysis service resource, service resource | Service that allows you to process CEL files from Affymetrix, Inc. GeneChip Exon 1.0 ST Arrays to identify alternative splicing. | is listed by: OMICtools | OMICS_00754 | SCR_008684 | 2026-08-12 10:49:45 | 4 | ||||||||||
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PROTOTYPE - Suspected Overlap Among OBO Foundry Candidate Ontologies Resource Report Resource Website 1+ mentions |
PROTOTYPE - Suspected Overlap Among OBO Foundry Candidate Ontologies (RRID:SCR_008834) | PROTOTYPE Suspected Overlap Among OBO Foundry Candidate Ontologies | production service resource, data analysis service, analysis service resource, service resource | THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. Service that determines the Suspected Overlap Among OBO Foundry Candidate Ontologies. | has parent organization: National Center for Biomedical Ontology | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_144632 | SCR_008834 | 2026-08-12 10:49:48 | 2 | |||||||||
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Channelrhodopsin-2 enables optical activation of neurons Resource Report Resource Website 1+ mentions |
Channelrhodopsin-2 enables optical activation of neurons (RRID:SCR_008833) | Channelrhodopsin-2 enables optical activation of neurons | production service resource, resource, material service resource, service resource | Laser tool that enables neurons to be optically silenced by pulses of yellow light, the light-activated chloride pump halorhodopsin (Halo), in a paper entitled Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. Temporally precise, noninvasive control of activity in well-defined neuronal populations is a long-sought goal of systems neuroscience. We adapted for this purpose the naturally occurring algal protein Channelrhodopsin-2, a rapidly gated light-sensitive cation channel, by using lentiviral gene delivery in combination with high-speed optical switching to photostimulate mammalian neurons. We demonstrate reliable, millisecond-timescale control of neuronal spiking, as well as control of excitatory and inhibitory synaptic transmission. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. The quest to determine how precise neural activity patterns mediate computation, behavior, and pathology would be greatly aided by a set of tools for reliably activating and inactivating genetically targeted neurons, in a temporally precise and rapidly reversible fashion. Having earlier adapted a light-activated cation channel, 1channelrhodopsin-2 (ChR2), for allowing neurons to be stimulated by blue light, we searched for a complementary tool that would enable optical neuronal inhibition, driven by light of a second color. Here we report that targeting the 1codon-optimized form of the light-driven chloride pump halorhodopsin from the archaebacterium Natronomas pharaonis (hereafter abbreviated Halo) to genetically-specified neurons enables them to be silenced reliably, and reversibly, by millisecond-timescale pulses of yellow light. We show that trains of yellow and blue light pulses can drive high-fidelity sequences of hyperpolarizations and depolarizations in neurons simultaneously expressing yellow light-driven Halo and blue light-driven ChR2, allowing for the first time manipulations of neural synchrony without perturbation of other parameters such as spiking rates. The Halo/ChR2 system thus constitutes a powerful toolbox for multichannel photoinhibition and photostimulation of virally or transgenically targeted neural circuits without need for exogenous chemicals, enabling systematic analysis and engineering of the brain, and quantitative bioengineering of excitable cells. | hardware, instrument, equipment | has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; | Anonymous donor ; MIT Media Lab ; Helen Hay Whitney Foundation |
PMID:17375185 | nlx_144630 | http://channelrhodopsin.org | SCR_008833 | 2026-08-12 10:49:52 | 3 | ||||||
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Functional Neurogenesis Resource Report Resource Website 1+ mentions |
Functional Neurogenesis (RRID:SCR_008830) | Functional Neurogenesis | data or information resource, narrative resource, blog | A blog focusing on the function of adult neurogenesis in the dentate gyrus of the hippocampus, including discussion of scientific research papers, methods and protocols, and other trends or observations about the field. | adult, neurogenesis, dentate gyrus, hippocampus, brain, neuron, anxiety, depressive disorder, memory, plasticity | nlx_144587 | SCR_008830 | Functional Neurogenesis - New neurons in the adult brain. How they work and what they are good for. | 2026-08-12 10:49:52 | 2 | |||||||||
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Genotype-IBD Sharing Test Resource Report Resource Website 100+ mentions |
Genotype-IBD Sharing Test (RRID:SCR_006257) | GIST | resource, software application, software resource | Software package to test if a marker can account in part for the linkage signal in its region. There are two versions of the software: Windows and Linux/Unix. | identical by descent, genotype, gene, genetic, genomic, unix, ms-windows, linux, linkage disequilibrium, linkage, association |
is listed by: Genetic Analysis Software has parent organization: Vanderbilt University; Tennessee; USA |
Vanderbilt Diabetes Center ; NHGRI HG00376; NIDDK DK62370; NHGRI N01-HG-15465 |
PMID:14872409 | nlx_154133 | http://phg.mc.vanderbilt.edu/content/gist | SCR_006257 | 2026-08-12 10:49:22 | 120 | ||||||
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Biobehavioral Resource Report Resource Website 10+ mentions |
Biobehavioral (RRID:SCR_008710) | data or information resource, narrative resource, blog | THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016. Biobehavioral blog on research and medicine as a continuum from biological mechanisms to behavioural phenomena., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_11905 | SCR_008710 | Biobehavioral | 2026-08-12 10:49:45 | 14 | ||||||||||
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MEDIE Resource Report Resource Website 1+ mentions |
MEDIE (RRID:SCR_006254) | MEDIE | production service resource, data analysis service, analysis service resource, service resource | An intelligent search engine to retrieve biomedical correlations from MEDLINE, based on indexing by Natural Language Processing and Text Mining techniques. You can find abstracts/sentences in MEDLINE by specifying semantics of correlations; for example, What activates p53 and What causes colon cancer. Semantic search uses a semantic query for finding biomedical correlations. Input a subject, a verb, and an object of a concept (or either of them) into a form. Results of the query will be shown in a second. (E.g., What does p53 activate? (subject=p53, verb=activate)) Reference: Miyao, Yusuke, Tomoko Ohta, Katsuya Masuda, Yoshimasa Tsuruoka, Kazuhiro Yoshida, Takashi Ninomiya and Jun''''ichi Tsujii (2006) Semantic Retrieval for the Accurate Identification of Relational Concepts in Massive Textbases. Proceedings COLING-ACL 2006. Sydney, Australia, pp. 1017--1024. | natural language processing, text mining, semantic search, computational linguistics, search engine |
is used by: BioLexicon is listed by: OMICtools is listed by: FORCE11 is related to: MEDLINE has parent organization: University of Tokyo; Tokyo; Japan has parent organization: National Centre for Text Mining |
nif-0000-06682, OMICS_01188 | http://www-tsujii.is.s.u-tokyo.ac.jp/medie/, https://www.force11.org/node/4643 | SCR_006254 | 2026-08-12 10:49:24 | 3 | ||||||||
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GeneTrail Resource Report Resource Website 100+ mentions |
GeneTrail (RRID:SCR_006250) | GeneTrail | production service resource, data analysis service, analysis service resource, service resource | A web-based application that analyzes gene sets for statistically significant accumulations of genes that belong to some functional category. Considered category types are: KEGG Pathways, TRANSPATH Pathways, TRANSFAC Transcription Factor, GeneOntology Categories, Genomic Localization, Protein-Protein Interactions, Coiled-coil domains, Granzyme-B clevage sites, and ELR/RGD motifs. The web server provides two statistical approaches, "Over-Representation Analysis" (ORA) comparing a reference set of genes to a test set, and "Gene Set Enrichment Analysis" (GSEA) scoring sorted lists of genes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | pathway, microarray, enrichment, genomic, proteomic, function, transcription factor, genomic localization, protein-protein interaction, coiled-coil domain, granzyme-b clevage site, motif, bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools is related to: KEGG is related to: TRANSPATH is related to: TRANSFAC is related to: Gene Ontology has parent organization: Saarland University; Saarbrucken; Germany |
PMID:17526521 | THIS RESOURCE IS NO LONGER IN SERVICE | biotools:genetrail, OMICS_02236 | https://bio.tools/genetrail | SCR_006250 | 2026-08-12 10:49:23 | 114 | ||||||
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Neurocritic Resource Report Resource Website 1+ mentions |
Neurocritic (RRID:SCR_006528) | Neurocritic | data or information resource, narrative resource, blog | The Neurocritic is a blog deconstructing the most sensationalistic recent findings in Human Brain Imaging, Cognitive Neuroscience, and Psychopharmacology. Born in West Virginia in 1980, The Neurocritic embarked upon a roadtrip across America at the age of thirteen with his mother. She abandoned him when they reached San Francisco and The Neurocritic descended into a spiral of drug abuse and prostitution. At fifteen, The Neurocritic''s psychiatrist encouraged him to start writing as a form of therapy. | human, brain imaging, cognitive neuroscience, psychopharmacology, brain, imaging, neuroimaging | nlx_144592 | SCR_006528 | The Neurocritic | 2026-08-12 10:49:28 | 2 | |||||||||
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Single Nucleotide Polymorphism Spectral Decomposition (SNPSpD) Resource Report Resource Website 10+ mentions |
Single Nucleotide Polymorphism Spectral Decomposition (SNPSpD) (RRID:SCR_008621) | SNPSpD | production service resource, data analysis service, analysis service resource, service resource | SNPSpD is a method of correcting for non-independance of single nucleotide polymorphisms (SNPs) in linkage disequilibrium (LD) with each other, on the basis of the spectral decomposition (SpD) of matrices of LD between SNP''s. Additionally, output from SNPSpD includes eigenvalues, principal-component coefficients, and factor loadings after varimax rotation, enabling the selection of a subset of SNPs that optimize the information in a genomic region. | bio.tools |
is listed by: Debian is listed by: bio.tools has parent organization: Queensland Institute of Medical Research |
National Health and MRC Australia 241916 | PMID:14997420 | biotools:snpspd, nif-0000-31985 | https://bio.tools/snpspd | http://genepi.qimr.edu.au/general/daleN/SNPSp | SCR_008621 | Single Nucleotide Polymorphism Spectral Decomposition | 2026-08-12 10:49:44 | 18 | ||||
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Lists2Networks Resource Report Resource Website 1+ mentions |
Lists2Networks (RRID:SCR_006323) | L2N | production service resource, data analysis service, analysis service resource, service resource | A web-based software system that allows users to upload lists of mammalian genes/proteins onto a server-based program for integrated analysis. The system includes web-based tools to manipulate lists with different set operations, to expand lists using existing mammalian networks of protein-protein interactions, co-expression correlation, or background knowledge co-annotation correlation, as well as to apply gene-list enrichment analyses against many gene-list libraries of prior biological knowledge such as pathways, gene ontology terms, kinase-substrate, microRNA-mRAN, and protein-protein interactions, metabolites, and protein domains. Such analyses can be applied to several lists at once against many prior knowledge libraries of gene-lists associated with specific annotations. The system also contains features that allow users to export networks and share lists with other users of the system. | high-throughput sequencing, analysis, gene, protein |
is listed by: OMICtools has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA |
PMID:20152038 | Free, Public, Account required | OMICS_02231 | http://www.lists2networks.org | SCR_006323 | Lists2Networks: Integrated analysis of gene/protein lists | 2026-08-12 10:49:24 | 3 |
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