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https://medicine.uiowa.edu/genetherapy/research-cores/comparative-pathology-core

Core facility which provides comprehensive necropsy, histology, and pathology services for animal models in order to facilitate translational research in animal models of cystic fibrosis. It also houses instrumentation which allows for high-throughput optimization of immunostaining protocols and has access to morphologic equipment that allow for the scanning of large tissue areas and morphometric quantification of histologic endpoints.

Proper citation: University of Iowa Center for Gene Therapy Comparative Pathology Core (RRID:SCR_015411) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10820/community_id/1418

Core that consists of three subcores: Hormone Assay and Analytical Services, Lipids, Lipoproteins, and Atherosclerosis, and Mouse Pathology. The Hormone Assay and Analytical Services provides analyses that facilitate research in diabetic, cardiovascular, and obese animal models. Lipids and Lipoproteins Subcore provides quantitative and qualitative measurements of plasma and tissue lipids and lipoproteins to researchers who use mice to study atherosclerosis, dyslipidemia, diabetes, obesity, hypertension, and other metabolic diseases. Mouse Pathology services include standard pathology testing in hematology, clinical chemistry, parasitology, microbiology, serology, molecular diagnostics, necropsy, and research histology and pathology expertise and counseling.

Proper citation: MMPC-Vanderbilt University School of Medicine Analytical Resources Core (RRID:SCR_015379) Copy   

•   Source: SciCrunch Registry

http://www.uc.edu/labs/mmpc/select-test/energy-balance.html

Core that specializes in total body/carcass analysis, measurement of oxygen consumption and carbon dioxide production, meal pattern analysis, and feeding mass/bouts, drinking volume, VO2 and VCO2.

Proper citation: MMPC-University of Cincinnati Medical Center Energy Metabolism Food Intake and Body Weight Regulation Core (RRID:SCR_015371) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/advanced-analytics

Core facility provides solutions for studying proteins, peptides, and other molecules, including mRNA and cDNA. The Core's immunotechnologies (IT) component provides consultation, ordering, and immunoassay services, and supports a variety of analytes in both traditional ELISA/EIA and xMAP-based multiplex bead assay formats.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Advanced Analytics Core (RRID:SCR_015613) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/large-animal-core

Core facility that provides consultation and procedural expertise on development on novel models of relevant digestive diseases in large animals.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Large Animal Models Core (RRID:SCR_015619) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org/GIConteCenter/pages/cores/proteomicsCore.html

Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Proteomics Core (RRID:SCR_015597) Copy   

•   Source: SciCrunch Registry

http://www.norc.uab.edu/corefacilities/physicalactivity

Core that provides physical activity services and consultation for UAB investigators. Services include aerobic fitness tests, supervised resistance training, submaximal ease/economy locomotion tests, and strength and functional tests, with respective measurements taken.

Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Physical Activity Core (RRID:SCR_015474) Copy   

•   Source: SciCrunch Registry

http://www.urology.wisc.edu/research/u54-george-m-obrien-center-for-benign-urology-research/rodent-urinary-function-testing-ruft-core/

Core that designs, validates, and disseminates protocols for rodent urinary function testing. It also provides urinary function testing services, expertise, laboratory space, vivarium, and equipment for complete mouse urinary function testing.

Proper citation: O'Brien Center for Benign Urologic Research at University of Wisconsin-Madision and University of Massachusetts-Boston Rodent Urinary Function Testing Core (RRID:SCR_015477) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org/GIConteCenter/pages/cores/imagingCore.html

Core facility that provides state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Image Core (RRID:SCR_015593) Copy   

•   Source: SciCrunch Registry

https://hddc.hms.harvard.edu/bio-repository-and-data-registry-human-material

Core facility that supports basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. It also aims to to forge connections and support collaboration between HDDC Clinical Associates and Members, support a well-organized infrastructure for acquisition and storage of clinical samples, and provide professional support in biostatistics and study design to HDDC members and Clinical Associates.

Proper citation: Harvard Digestive Diseases Center Bio-Repository and Data Registry for Human Material (RRID:SCR_015590) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org/GIConteCenter/pages/cores/integratedPhysiology.html

Core facility that provides Center investigators and their laboratories the tools and advice needed to establish and study mouse (including transgenic and knockout) and human (i.e. GI organoids) physiology of GI disease.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Integrated Physiology Core (RRID:SCR_015591) Copy   

•   Source: SciCrunch Registry

http://www.med.umich.edu/mgpc/cores/pil.htm

Core facility whose services include the following programs: Imaging Core Program, Proteomics Core Program, Protein Folding Core Program, and Consultation.

Proper citation: University of Michigan Center for Gastrointestinal Research Protein Localization, Identification and Folding Core (RRID:SCR_015609) Copy   

•   Source: SciCrunch Registry

http://www.med.umich.edu/mgpc/cores/maic.htm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 8,2025. Core whose services include consultation, Nucleic Acid Isolation, Microbiome (16S) Data Analysis, MiSeq-base 16S rRNA Gene Sequencing, Genomic/Metagenomic shotgun sequencing, Bacterial transcriptomics and metatranscriptomics, Multiplatform Metabolomic Profiling, Metabolomic sample preparation, and Germ-free & Gnotobiotic Mouse Facilities.

Proper citation: University of Michigan Center for Gastrointestinal Research Microbiome and Metabolomics Core (RRID:SCR_015611) Copy   

•   Source: SciCrunch Registry

http://cunorc.org/cores/energy-core/

Core facility for University of Colorado Anschutz Medical Campus Nutrition and Obesity Research Center. Provides support for measurement of components of energy balance and for assessing consequences of alterations in energy balance. Provides expertise and support for obesity and nutrition related basic, clinical, translational, and transdisciplinary research for NORC investigators and its affiliates. Provides services to assess body composition, bone density, physical fitness, and energy expenditure values in research participants.

Proper citation: University of Colorado Anschutz Medical Campus Nutrition and Obesity Research Center Energy Balance Assessment Core Facility (RRID:SCR_015914) Copy   

•   Source: SciCrunch Registry

https://sdrc.stanford.edu/sdrc-research-cores/dgac/home/

Core facility that offers library preparation and sequencing services on a variety of platforms - Illumina HiSeq 4000, MiSeq, HiSeq 2500 and PacBio Sequel - as well as bioinformatics analysis. It can sequence a variety of commercial sample preparation kits as well as custom workflows. DGAC provides access to high throughput sequencing and analysis to researchers at the Stanford Diabetes Research Center.

Proper citation: Stanford Diabetes Research Center Diabetes Genomics Analysis Core (RRID:SCR_016213) Copy   

•   Source: SciCrunch Registry

http://sph.unc.edu/norc/research-partnerships/

THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 23,2019. Center that provides bioinformatics and metabolomics support to UNC members for nutrition and obesity-related clinical and translational research.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Research Facilitation Program (RRID:SCR_015480) Copy   

•   Source: SciCrunch Registry

http://cobre.pbrc.edu/cores/genomics/

Provides services which include Sanger and next-generation DNA sequencing,DNA fragment analysis,qualitative and quantitative analysis of DNA, protein, and RNA samples, quantitative PCR, microarray RNA labeling, hybridization, and scanning robotics,bioinformatics.Individual and small group training and consultation services are offered for sequence analysis, real-time PCR, next-generation sequencing and microarray analysis.

Proper citation: Louisiana State University Pennington Biomedical Research Center Genomics Core Facility (RRID:SCR_018675) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/umpc

UMass Metabolic Disease Research Center (MDRC), formerly the National Mouse Metabolic Phenotyping Center, is a core facility that performs standardized experiments using state-of-the-art equipment for the purpose of investigating transgenic mouse models of diabetes, obesity, and metabolic liver disease. Provides metabolic and functional characterization of mouse models of human diseases that are developed by academic and industry researchers in joint efforts to understand metabolic diseases and to identify new therapies.

Proper citation: University of Massachusetts Medical School Metabolic Disease Research Center Core Facility (RRID:SCR_018672) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/cellbio.html

Core that gives support including experimental design, islet isolation, and performance of and training in an expansive range of assays for physiological and morphometric assessment of pancreatic islet function and growth. It contributes to the basic and translational research activities of the Institute of Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine of the University of Pennsylvania. Its services include perform individual islet and single cell fluorescence imaging, respirometry with islet batches using a Seahorse Extracellular Flux Analyzer, perifusion coupled with respirometry, and closed respirometry experiments for our investigators.

Proper citation: University of Pennsylvania School of Medicine Penn Diabetes Research Center Pancreatic Islet Cell Biology Core Facility (RRID:SCR_008265) Copy   

•   Source: SciCrunch Registry

http://amp.pharm.mssm.edu/X2K/

Software tool to produce inferred networks of transcription factors, proteins, and kinases predicted to regulate the expression of the inputted gene list by combining transcription factor enrichment analysis, protein-protein interaction network expansion, with kinase enrichment analysis. It provides the results as tables and interactive vector graphic figures.

Proper citation: eXpression2Kinases (RRID:SCR_016307) Copy   

•   Source: SciCrunch Registry