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http://www.scienceexchange.com/facilities/waksman-institute-of-microbiology

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 10, 2023. Our mission is to conduct research in microbial molecular genetics, developmental molecular genetics, plant molecular genetics, and structural and computational biology. We also provide a catalyst for general university initiatives, a life science infrastructure, undergraduate and graduate education, and a public service function for the State of New Jersey. The Institute employs faculty teams that concentrate on certain classes of organisms amenable to genetic analysis such as bacteria and fungi (E. coli and yeast), animal systems (e.g., Drosophila), and plants (Arabidopsis, tobacco, and maize). Although the Institute focuses on basic questions in microbial, animal, and plant research, it continues to engage in extensive technology transfer of its basic discoveries.

Proper citation: Rutgers Waksman Institute of Microbiology Labs and Facilities (RRID:SCR_012728) Copy   

•   Source: SciCrunch Registry

http://ocs.med.nyu.edu/immunohistochemistry

The Immunohistochemistry Core, a component of the Experimental Pathology Shared Resource, is located in Bellevue Hospital within the NYULMC Department of Pathology''s Anatomic Pathology clinical space. The laboratory serves as an immunohistochemical antibody repository with a catalog of over 900 antibodies. Antibodies are in stock and available for use in the core laboratory for the collection of experimental immunohistochemistry data. The laboratory develops immunohistochemical protocols for new antibodies (commercial or proprietary) that have not been tested in fresh, frozen, fixed human or animal tissues and cells. In addition to performing manual labeling, the laboratory is equipped with two Ventana NEXES and one Discovery automated immunohistochemical staining instruments. The laboratory uses human and animal tissue micro-arrays for validation and employs a wide variety of antigen retrieval methods for protocol development. The core offers tyramide and polymer amplification methods (manual) and single or two color chromogenic immunohistochemistry. The laboratory has also commenced developing protocols and validating antibodies for immunoflorescence in frozen and FFPE tissue samples. The laboratory faculty and staff are available to provide hands-on informal training, as well as guidance and support for the design and execution of experiments involving histopathology and immunohistochemistry of human and animal cells and tissues. In conjunction with the Histopathology Core Laboratory, the Immunohistochemistry Laboratory can also assist investigators with routine and advanced histopathologic services for tissue and cell specimens (including guidance on initial processing steps: grossing/tissue preparation, processing, embedding, paraffin/frozen microtomy) for samples destined for histopathological interpretation and analysis. In addition, we offer extensive options for special and routine histochemical and immunohistochemical labeling of both human and animal model cells and tissues.

Proper citation: NYU Immunohistochemistry Core (RRID:SCR_012721) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/high-throughput-screening-service-uc-irvine

With the completion of the genome sequence, that offers us a variety of new genes to study, and advances in combinatorial chemistry, that delivers large numbers of synthetic compounds to test, high__������throughput screening (HTS) is becoming a necessary research endeavor. We specialize in HTS of G protein__������coupled receptors (GPCRs). Ligand recognition is quantified in binding experiments or monitored by second messenger responses. One technology that we use is the FLIPR technology that allows for real__������time fluorescent measurements.

Proper citation: UC Irvine High Throughput Screening Service (RRID:SCR_012725) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/macromolecular-x-ray-crystallography-core-facility

The Macromolecular X-ray Crystallography Core Facility of Scripps FL offers state-of-the-art equipment and resources to scientists inside and outside of the Scripps FL campus by providing crystallographic analysis of their chosen biological macromolecules. The core facility offers and operates as a full service core by performing protein crystallization, X-ray diffraction data collection (both in-house and at Argonne National Laboratory) and processing, phasing, crystallographic refinement, model building, and visualization. The structural data obtained by the core will provide scientists with a wealth of information including but not limited to biological functions, 3D-folding, ligand binding (small molecule or protein), or mutational effect of target macromolecules of their interests.

Proper citation: Scripps Florida Macromolecular X-ray Crystallography Core Facility (RRID:SCR_012727) Copy   

•   Source: SciCrunch Registry

http://www.ohsu.edu/xd/research/centers-institutes/onprc/research-services/research-support/virology.cfm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 5, 2022. Core facility that provides the following services: DNA isolation service, RNA isolation service, Cloning and endotoxin-free plasmid preparation service, Virus plaque assay, SIV p27 protein ELISA, HIV p24 protein ELISA with sample prep, Real time PCR titer of lentivirus prep with sample prep, Coculture of animal tissues/fluids service, Virus plaque purification service, Virus growth curve service, Protein determination, Bradford method, Crude viral DNA prep service, Gradient purified viral DNA prep service, Southern blot for viral DNA, Viral Real-time PCR, RhCMV Real-time PCR, HSV 1/2 B virus antibody ELISA, single dilution service, RhRRV antibody ELISA, single dilution, RhSFV antibody ELISA, single dilution, SIV antibody ELISA, single dilution, Virus antibody ELISA, RhCMV antibody ELISA, Virus neutralization service, Polyclonal IgG preparation, SIV in vitro susceptibility, p27 ELISA, Vaccinia (MVA) virus plaque assays, Antiviral antibody determination by ELISA, SIV in vitro infectivity (leukocytes) service, Viral load quantification with qPCR, Virus detection using nested PCR, Virus stock production, Cytomegalovirus plaque assays and purification, Cytomegalovirus stock and vector production, Western blot service for viral protein, Cell sample processing and banking, Nucleic acid isolation and purification service, Virus cloning and plasmid preparation service, Vaccinia (MVA) virus stock and vector production. The Core''''s overall goal is to advance the efforts of the Oregon National Primate Research Center (ONPRC), the Vaccine and Gene Therapy Institute (VGTI), and collaborative research programs focused on nonhuman primate (NHP) infectious disease models and those using viral vectors as tools to modify genes or deliver macromolecules through provision of expertise, reagents, standardized assays, and training in the use of infectious viral agents in their research programs. The MVSC provides specialized expertise and infrastructure in five essential areas: * Virus identification and quantification in clinical specimens * Production of virus stocks, virus vectors, and viral antigen preparations * Serologic assays to assess host antiviral immune responses * Maintenance of cell stocks and sample processing * Development of new reagents and standardized assays The MVSC has considerable experience and expertise in both viral diagnostics and production, particularly for AIDS and CMV pathogenesis and vaccine studies, and in adenoviral vector production.

Proper citation: OHSU Molecular Virology Support Core (RRID:SCR_012730) Copy   

•   Source: SciCrunch Registry

https://planttransformationlab.wordpress.ncsu.edu/

Provides innovative solutions, technologies, expertise, training, and services for research and applications related to plant transformation. The PTL staff and facilities are available for research collaborations; core resources are available for user-driven projects with cost recovery; fee-based plant transformation services can be provided for the NCSU community and external partners.

Proper citation: North Carolina State University Plant Transformation Laboratory Core Facility (RRID:SCR_012706) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/histology-core-wustl

The Histology Core has all the requisite equipment and reagents to enable a variety of tissue processing, embedding and sectioning protocols, including epon/araldite, glycol and methyl methacrylate, polyethylene glycol (PEG), paraffin and cryosectioning. Users of the Histology Core can choose to submit full service jobs and allow core personnel to embed, section and counterstain fixed tissue samples or they can sign up to use a microtome and cut the tissue themselves. Training on any aspect of the histologic process is available on request. All core services are equally available to core members and non-members on a first-come first-served basis.

Proper citation: WUSTL Histology Core (RRID:SCR_012700) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-organic-photonics-and-electronics-cope-georgia-tech

The Georgia Tech Center for Organic Photonics and Electronics (COPE) is a premier national research and educational resource center that creates flexible organic photonic and electronic materials and devices that serve the information technology, telecommunications, energy, and defense sectors. COPE creates the opportunity for disruptive technologies by developing new materials with emergent properties and by providing new paradigms for device design and fabrication. This helps enable a new generation of devices and systems that meet the challenges that these sectors and our ever-changing society face in this decade and the future.

Proper citation: Georgia Tech Center for Organic Photonics and Electronics (RRID:SCR_012702) Copy   

•   Source: SciCrunch Registry

https://med.virginia.edu/bioinformatics-core/

Core serves as a centralized resource for providing expert and timely bioinformatics consulting and data analysis solutions. The core offers services to investigators both within and outside UVA on both grant-funded and chargeback-based projects for management and analysis of large-scale biological datasets produced by high-throughput genomics experiments. The Core's mission is to build and maintain an infrastructure that enables the application of strong bioinformatics analysis with a measurable impact on the ability of UVa investigators to both publish their work and obtain new funding.

Proper citation: University of Virginia Bioinformatics Core (RRID:SCR_012718) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/texas-a-m-university

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22,2024. Portal listing the Texas A and M University's labs and facilities, which include the TAMU Protein Chemistry Lab and the TIGM Transgenic Core.

Proper citation: Texas A and M University Labs and Facilities (RRID:SCR_001041) Copy   

•   Source: SciCrunch Registry

http://www.albany.edu/genomics/proteomics/

A core facility that provides services in the identification of individual proteins, characterization of entire protein complexes or biosimilars, and global analysis to discover changes in the proteomes of different samples. The core also specializes in the development of custom assays for quantitation of specific molecules in complex clinical samples.

Proper citation: UAlbany Proteomics Core Facility (RRID:SCR_001048) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/louisiana-state-university

Portal for Louisiana State University labs and facilities which include the AgCenter Biotechnology Laboratory, a core facility that provides basic and applied research expertise to support researchers in the LSU system as well as those in other academic institutions and industry. The ABL consists of three units: the Protein Facility, the Plant Transformation Facility and the Animal Cell Culture Facility.

Proper citation: Louisiana State University Labs and Facilities (RRID:SCR_001046) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/miami-university

A portal listing Miami University's labs and facilities which include the Center for Bioinformatics and Functional Genomics. The CBFG is the onsite core molecular biology and bioinformatics resource at Miami University that focuess mainly on DNA and protein analysis as well as expertise in robotics liquid handling.

Proper citation: Miami University Labs and Facilities (RRID:SCR_001040) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/bauer-core-laboratory-fas-harvard

Core facility that provides the following services: Liquid handling, Long read sequencing, Cell sorting service, Cell analysis service, Imaging systems service, Microarrays service, Sequencing service, Genotyping service, Fragment analysis, Solexa DNA sequencing service, Solexa gene expression service, Solexa small RNA service, Solexa ChIP-Seq service, Real-time quantitative PCR service, Protein-molecule interaction service, Library replication service, Nucleic acid isolation service, Nucleic acid shearing service, DNA, RNA and protein sample analysis service. Their goal is to advance research efforts in the life sciences that cannot readily be accomplished in the traditional academic laboratory because of a need for expensive instrumentation or automation, scientific or organizational infrastructure, or multidisciplinary expertise. To promote cutting-edge research and to foster scientific collaborations, we make our extensive laboratory and computational resources available to scientists at Harvard. Our technical staff provide expertise and hands-on training in protocols and the use of instrumentation for a nominal fee. Researchers can sign up to use the instrumentation through an on-line scheduling system and conduct their experiments independently.

Proper citation: Harvard FAS Bauer Core Laboratory (RRID:SCR_001031) Copy   

•   Source: SciCrunch Registry

https://www.scienceexchange.com/labs/university-of-oxford

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. An independent portal that lists the labs and facilities at the University of Oxford.

Proper citation: University of Oxford Labs and Facilities (RRID:SCR_001022) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.edu/shared-resources/gene-targeting-and-transgenic

Facility which provides researchers with transgenic mouse technologies, methods, and animal models. Knockout mice, transgenic mice, and mice on multiple strain backgrounds are provided.

Proper citation: RPCI Gene Targeting and Transgenic Shared Resource (RRID:SCR_001020) Copy   

•   Source: SciCrunch Registry

http://www.brighamandwomens.org/Departments_and_Services/radiology/Research/BRIC/default.aspx

Imaging Core facility that provides a comprehensive research imaging service to meet the needs of investigators and research subjects using imaging facilities at Brigham and Women's Hospital (BWH). A unique feature of BRIC is the complete anonymity of research subjects. Research image scheduling, image acquisition and image storage are all kept completely separate from BWH clinical Radiology systems. The BRIC provides the administrative infrastructure, customer service architecture and institutional support to promote investigative applications of imaging technologies.

Proper citation: BWH Research Imaging Core (RRID:SCR_002708) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/igen

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Certified clinical laboratory (ISO15189). To clinicians in oncology we offer genetic and epigenetic analyses together with interpretation. iGen also provides professional genetic counseling ?????????????????? a healthcare service, which advises people who are at the risk of hereditary cancer. In the research field iGen performs assay development and genotyping services. Our customers are clinical laboratories, research groups and genetic tests distributors. To improve molecular diagnostics in cancer treatment iGen is continuously carrying out research and applied science projects. Currently, our main cooperation partners are the Competence Centre of Cancer Research and North Estonian Medical Centre. We are looking for other cooperation opportunities, and are interested in participating in national and international cooperative research projects, to which we can contribute with our expertise in molecular diagnostics. Our laboratory and office are situated in Tehnopol Tallinn Science Park territory, next to the campus of Tallinn University of Technology. Prices quoted are highly dependable on the number of samples and are given based on full plate/machine, please contact us for pricing for smaller projects.

Proper citation: iGen (RRID:SCR_009433) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-358b-059e-550e-f59280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core provides intellectual guidance for quantitative aspects of the design and analysis of center studies and expertise in biostatistical methods, environmental risk assessment, Geographic Information System (GIS) , spatial statistics, molecular biology, bioinformatics and statistical genetics. Core runs a regular seminar series and often sponsors short courses on specialized topics of interest to the community.

Proper citation: Harvard School of Public Health Environmental Statistics and Bioinformatics Core Facility (RRID:SCR_009822) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/genome-technology-center

Core provides range of services related to genome, epigenome, and transcriptome analysis. Offers technologies including Illumina deep sequencing and sample preparation for variety of applications, including DNA and RNA sequencing (DNA- and RNA-seq), exome sequencing, targeted capture, chromatin immunoprecipitation sequencing (ChIP-seq), methylation sequencing (Methyl-seq), metagenomics, and many others;Automation of Illumina library and targeted capture preps, including 16S ribosomal RNA (rRNA) sequencing;Oxford Nanopore sequencing (long reads);Bio-Rad Droplet Digita polymerase chain reaction (PCR);Nanostring nCounter;Single-cell RNA- and DNA-seq using the C1 Auto Prep System from Fluidigm, and 10x Genomics Chromium System.Provides expertise on strategies to achieve research goals in any field related to genomics, and can tailor bioinformatics analysis to individual project. If you supply us with nucleic acids, we can perform every step required to help you achieve your desired results.

Proper citation: New York University School of Medicine Langone Health Genome Technology Center Core Facility (RRID:SCR_017929) Copy   

•   Source: SciCrunch Registry