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https://medschool.cuanschutz.edu/corefacilities/cryo-em

Provides equipment, expert technical assistance and image analysis expertise to enable all aspects of macromolecular structure determination by single particle cryo-electron microscopy.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource CryoEM Core Facility (RRID:SCR_021999) Copy   

•   Source: SciCrunch Registry

https://medicine.tamu.edu/imil

Core supports research progress and grant development by encouraging researchers to explore advanced imaging modalities and to incorporate them into their existing research programs.Provides technical expertise and cutting edge microscope systems to support research of faculty and staff of Texas A&M University Health Science Center, Texas A&M University, and all other campuses.IMIL includes six microscopy rooms, supporting facilities, and image processing station.Technical staff is available to train and assist with design, implementation, and analysis of experiments as well as assist in troubleshooting.

Proper citation: Texas A&M Health Science Center Integrated Microscopy and Imaging Laboratory Core Facility (RRID:SCR_021637) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/corefacilities/nmr/home

Core enables study of biomolecular structure, dynamics and interactions in solution at atomic level. Provides NMR spectrometers from 600 MHz to 900 MHz equipped for biomolecular NMR studies. Equipment include 900 MHz Bruker Avance Neo with Oxford 21 T magnet - TCI Cryoprobe 600 MHz Bruker Avance Neo with Bruker Sample Jet (2024) - TCI Cryoprobe 600 MHz Varian Inova with HCN cryoprobe.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource NMR Core Facility (RRID:SCR_021997) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/corefacilities/x-ray-crystallography

Core performs all aspects of structure determination of large biomolecules such as proteins and nucleic acids including macromolecular crystallization, crystal screening, molecular structure and model building.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource X Ray Crystallography Core Facility (RRID:SCR_021998) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/pathology/molecular-pathology

Molecular Pathology Section offers clinical grade sample processing and molecular testing for research cases.All services are performed in CLIA certified environment and all molecular assays are accompanied by full data analysis including bioinformatics analysis for NGS data.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Pathology Shared Resource Molecular Pathology Core Facility (RRID:SCR_021995) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/animal-imaging/irradiation

Core specializes in targeted irradiation of small animals for use in preclinical trials of radiation therapy. Through use of XRAD-SmART Irradiator, core can use x-ray fluoroscopy and on board CBCT to accurately irradiate small lesion areas while protecting normal tissue. Provides experiment design, data analysis, and dosimetry calculations, as well as longitudinal acquisition of CBCT for temporal assessment of tumor growth kinetics.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Small Animal Image Guided Radiation Therapy Core Facility (RRID:SCR_021996) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/pediatrics/sections/developmental-biology/organoid-tissue-modeling-shared-resource

Core facilitates access, generation, and usage of novel in vitro mouse and human organoid systems to promote innovative basic and translational research and disease modeling. Provides expertise in genome editing technologies for targeted knock outs, point mutations, and reporter generation in organoid systems. Provides many specialized medias and reagents to support most common organoid culture systems.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Organoid and Tissue Modeling Shared Resource Core Facility (RRID:SCR_021993) Copy   

•   Source: SciCrunch Registry

https://www.creative-biolabs.com/

Custom service provider that has extensive experience in various antibody production and engineering fields.Services includes mouse and rat monoclonal antibody production using hybridoma technology, human, monkey, rabbit, chicken, dog, llama and camel monoclonal antibody production using various antibody library technologies (including phage display, bacterial display and yeast display).Conducting in depth antibody humanization and affinity maturation using phage display and DNA mutagenesis approaches.OEM services for bulk scale antibody manufacturing, including bacterial production of scFv, diabody, tandem scFv, miniantibody and Fab, and mammalian cell expression of minibody, chimeric IgG, and IgG, are also available at the most competitive price in industry.

Proper citation: Creative Biolabs Core Facility (RRID:SCR_021767) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/cell-center-services/

Facility provides basic cell culture training and services in various cell culture and related procedures e.g. Mycoplasma and Endotoxin testing. Services include cell culture at various scales, expansion of primary cells, seed cell cultures from on site cell bank, cell storage; large scale growth of hybridoma and other cell lines followed by antibody purification by protein G column or recombinant protein production; EBV induced transformation of lymphocytes.Offers hybridoma generation by cell fusion and screening and, transfection of mammalian cells. Facility prepares specialized cell culture media, Drosophila media and, various tissue culture and molecular biological reagents.

Proper citation: University of Pennsylvania Perelman School of Medicine Cell Center Services Core Facility (RRID:SCR_022391) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/cnsc/

Provides expertise in medicinal chemistry, metal chelate chemistry, polymer synthesis, nanoparticle production and surface functionalization, and site-specific antibody labeling. Our chemists provide custom, problem specific support for researchers in medical, chemical, and materials science fields. Specific services include consultation and assistance with the design of chemical/medicinal compounds, in house synthesis of chemical/medicinal compounds, custom nanoparticle design and synthesis, custom nanoparticle surface functionalization, polymer and dendrimer synthesis, and site specific antibody labeling.

Proper citation: University of Pennsylvania Perelman School of Medicine Chemical and Nanoparticle Synthesis Core Facility (RRID:SCR_022390) Copy   

•   Source: SciCrunch Registry

https://wiki.umontreal.ca/spaces/plateformes/pages/189568061/Core+Facilities+-+CI2B

Offers instruments and services to support research in microscopy.

Proper citation: University of Montreal BioImaging Platform Core Facility (RRID:SCR_022311) Copy   

•   Source: SciCrunch Registry

https://hostmicrobe.org/

Provides services in disciplines of genomics, microbiology and immunology. We engage in collaborative projects that benefit from close interactions with veterinarians and human clinicians alike.

Proper citation: University of Pennsylvania School of Veterinary Medicine Center for Host Microbial Interactions Core Facility (RRID:SCR_022310) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cbica/

Offers development and application of advanced computational and analytical techniques that quantify morphology and function from biomedical images, as well as on relating imaging phenotypes to genetic and molecular characterizations, and on integrating this information into diagnostic and predictive tools in era of personalized medicine. Computational methods can contribute significantly to automated, reproducible and quantitative interpretations of biomedical images. Translates advanced computational and analytical imaging methods to clinic, by providing forum in which interactions between researchers and clinicians facilitate bidirectional flow of ideas, algorithms and data between laboratory and clinic.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Biomedical Image Computing and Analytics Core Facility (RRID:SCR_022397) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/CAMIPM/

Core dedicated to development and application of innovative, novel magnetic resonance and optical imaging techniques. Provides research and computing resources for projects with focus on developing instrumentation, methodologies, and data analysis techniques for quantitative assessment of functional, structural, and metabolic parameters in humans with use of multinuclear magnetic resonance, novel spectral, perfusion, functional, and optical imaging techniques.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Advanced Metabolic Imaging in Precision Medicine Core Facility (RRID:SCR_022396) Copy   

•   Source: SciCrunch Registry

https://pennbrain.upenn.edu/

Provides infrastructure support for research on human cognition, perception, affect, disordered cognition, and extension to preclinical models. By consolidating methodological expertise in these domain areas as services, center seeks to facilitate cutting edge research using largely shared set of methods and tools for elucidating brain behavior relationships in health and disease.

Proper citation: University of Pennsylvania Perelman School of Medicine Brain Science Service Center Core Facility (RRID:SCR_022394) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/idom/drc/cores/rodent.html

Core (RMPC, formerly MPPMC) is metabolic core. Offers technology and phenotyping services to allow investigators to study metabolism in pre-clinical rodent models. Services include measurements of body composition (fat and lean mass) using NMR and DEXA, energy balance (food intake, locomotor activity, energy expenditure) using indirect calorimetry in either Columbus Instruments CLAMS system or Sable Systems Promethion System (with optional gas analyzer), and other in vivo metabolic phenotyping services (glucose clamps, insulin and glucose tolerance tests, telemetric monitoring of blood glucose or blood pressure, bomb calorimetry).

Proper citation: University of Pennsylvania Perelman School of Medicine Rodent Metabolic Phenotyping Core Facility (RRID:SCR_022427) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/ipsccore/

Provides resources for disseminating human pluripotent stem cell technology within UPenn and surrounding research communities. �Our services include derivation of patient specific iPSCs, genome engineering of stem cell lines using CRISPR/Cas9 technology, and lineage specific differentiation of iPSCs/hESCs in 2D and 3D organoid culture.�Core has large collection of patient derived iPSC lines and cell lines of gastrointestinal tract (esophageal, pancreatic and intestinal) available to users.�Committed to training investigators in stem cell culture techniques and providing quality tested stem cell reagents to users.

Proper citation: University of Pennsylvania Perelman School of Medicine Induced Pluripotent Stem Cell Core Facility (RRID:SCR_022426) Copy   

•   Source: SciCrunch Registry

https://qb3.berkeley.edu/facility/ctaf-htsf/

Facility provides expert staff for training, services, and cell culturing space for HT automated cell seeding, liquid handling equipment, multi label plate reader and high content automated confocal imaging for any type of multi well, multi conditional mammalian cell experiments.

Proper citation: University of California at Berkeley QB3 High Throughput Screening CoreFacility (RRID:SCR_022304) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/ris/

Shared resource machine shop serving various University of Pennsylvania Schools and Departments. Assists researchers to design and construct both laboratory and clinical instruments.

Proper citation: University of Pennsylvania Perelman School of Medicine Research Instrumentation Shop Core Facility (RRID:SCR_022424) Copy   

•   Source: SciCrunch Registry

https://hpc.ncsu.edu/main.php

Core, available through NC State Office of Information Technology, provides entry and intermediate level computing resources and consulting support for research and instruction.

Proper citation: North Carolina State University High Performance Computing Services Core Facility (RRID:SCR_022168) Copy   

•   Source: SciCrunch Registry