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https://vetmed.tamu.edu/cvm-histology-lab/research-histology-unit/

Provides histology (including cryosectioning, IHC and IFC) digital pathology and veterinary pathology (board certified veterinary pathologist on staff) services.

Proper citation: Texas A and M University Veterinary Medicine and Biomedical Sciences Research Histology Unit Core Facility (RRID:SCR_022201) Copy   

•   Source: SciCrunch Registry

https://it.hms.harvard.edu/rc/core

Promotes deeper collaboration across Harvard biomedical research ecosystem.This includes improved capabilities and performance by establishing more transparent and sustainable IT services for our research community.

Proper citation: Harvard Medical School Research Computing Core Facility (RRID:SCR_022289) Copy   

•   Source: SciCrunch Registry

https://ibt.tamu.edu/cores/protein-production-core/index.html

Core provides cloning, expression and purification services of functional proteins at scale that meets the quantity and purity benchmarks for structural, biophysical, biochemical, and therapeutics studies; characterizes macromolecular biophysics and interaction energetics using instrumentation and techniques that can analyze association and kinetic binding constants by surface plasmon resonance, enthalpies and entropies of binding by isothermal titration calorimetry, as well as determination of stoichiometry, stability, and homogeneity by both techniques.

Proper citation: Texas A and M Health Science Center IBT Protein Production, Characterization and Molecular Interaction Core Facility (RRID:SCR_022200) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/sharedinstrumentation/polymeric-and-optical-materials-characterization-shared-facility

Facility specializes in material characterization of polymers, hydrogels, liquid crystals, and composites.

Proper citation: University of Colorado Boulder Polymeric and Optical Materials Characterization Shared Core Facility (RRID:SCR_022288) Copy   

•   Source: SciCrunch Registry

https://microbiome.forsyth.org/

Offers Next Generation Sequencing (NGS) and comprehensive data analyses and interpretation for 16S rRNA gene amplicon sequences and other big data sequence applications. Offers analyses of previously obtained sequences. Many investigators are familiar with Human Oral Microbe Identification using Next Generation Sequencing (HOMINGS) as well as its predecessor the Human Oral Microbe Identification Microarray (HOMIM) for rapid 16S rDNA analyses of oral clinical samples. We continue in that tradition using bioinformatic methodology, which will provide the best possible taxa identification.

Proper citation: Forsyth Institute Oral Microbiome Core Facility (RRID:SCR_022166) Copy   

•   Source: SciCrunch Registry

https://www.cshl.edu/research/cancer/flow-cytometry/

Resource provides equipment, training, and operating assistance for cell sorting and analysis. Facility staff oversees equipment maintenance, trains new users, and assists with assay development and operation of equipment.

Proper citation: Cold Spring Harbor Laboratory Flow Cytometry Shared Resource Core Facility (RRID:SCR_022164) Copy   

•   Source: SciCrunch Registry

https://www.abdn.ac.uk/ims/facilities/cytometry/

Provides services and expertise in flow cytometry to government agencies, industry, educational and private individuals.

Proper citation: University of Aberdeen Iain Fraser Cytometry Centre Core Facility (RRID:SCR_022315) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/centers-laboratories/center/center-for-host-microbial-interactions

Offers consultation and laboratory services for high-throughput sequencing (HTS) experiments, with particular expertise and interest in microbiome/metagenome and RNA-seq applications. Provides instrumentation, including Illumina NextSeq 2000 and single cell platforms from 10X genomics and 1CellBio. Offers full service options, as well as hands on instruction for trainees who want to learn best practices for wet lab aspects of genomics experiments. Offers consultation services for all phases of HTS studies, from study design to bioinformatics analysis.

Proper citation: University of Pennsylvania Penn Vet Center for Host Microbial Interactions Core Facility (RRID:SCR_022434) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/electronmicroscopyresourcelab/

Training and service facility dedicated to providing both conventional transmission electron microscopy of cells and tissues and state of the art cryo-electron microscopy and cryo-electron tomography for structural investigation of macromolecules and cells.

Proper citation: University of Pennsylvania Perelman School of Medicine Electron Microscopy Resource Lab Core Facility (RRID:SCR_022375) Copy   

•   Source: SciCrunch Registry

https://bioinfo.med.upenn.edu/

Core provides bioinformatics services that include data analysis and consultation and building of efficient pipelines that handle various biomedical data including Next-Generation Sequencing (NGS) data.

Proper citation: University of Pennsylvania Perelman School of Medicine Bioinformatics Core Facility (RRID:SCR_022374) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cdbmicroscopycore/

Core provides personalized assistance on all aspects of imaging, from tips on sample preparation to training on one of our microscopes to assistance with image data analysis. Facility houses confocal microscopes, Bruker Vutara 352 super resolution system, Zeiss Z.1 Lightsheet system, three widefield light microscopes, and several computers dedicated to image processing and analysis. Offers scanning electron microscope sample preparation and imaging.

Proper citation: University of Pennsylvania Perelman School of Medicine Cell and Developmental Biology Microscopy Core Facility (RRID:SCR_022373) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cfar/virus-reservoirs.html

Facility provides comprehensive viral and molecular support in area of basic, translational and clinical HIV research, consultation, training, and mentoring.Is available to develop customized viral and molecular support services as needed. Offers deep sequencing support and single genome amplification services.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for AIDS Research Virus and Reservoirs Core Facility (RRID:SCR_022403) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/chps/

CHPS is comprised of several Clinical Research Cores designed to facilitate research process. Provides resources, environment, operations, and training to support and promote high quality clinical and translational research by qualified investigators.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Human Phenomic Science (CHPS) (RRID:SCR_022402) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/cear.html

Core aims to facilitate and build capacity for community based research and community engagement, while enhancing translation of research and technological developments to key public health and community stakeholders. Offers consultation on community engagement, training in participatory research methods, and assistance with development, implementation, and evaluation of community translation activities. Core is part of the Penn Institute for Translational Medicine and Therapeutics (ITMAT).

Proper citation: University of Pennsylvania Perelman School of Medicine Community Engagement and Research Core Facility (RRID:SCR_022408) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/tcmf/

Facility provides centralized service to efficiently produce genetically altered mice for basic research.� They include transgenic, chimeric and genome edited mice carrying transgenes or gene knockout and Knockin of specific interest.�Core also provides embryo and sperm cryopreservation as well as in vitro fertilization and re-derivation of live and cryopreserved lines, along with long-term storage of cryopreserved samples.

Proper citation: University of Pennsylvania Perelman School of Medicine Transgenic and Chimeric Mouse Core Facility (RRID:SCR_022388) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/neuronsrus/

Core supplies suspensions of neuronal cells prepared from rodent brain for various downstream applications, including primary cell culture. Supplies rat or mouse cells isolated from cortex or hippocampus either in suspension or plates. Custom dissection services are available for other brain regions or for user supplied genetically modified mice.

Proper citation: University of Pennsylvania Perelman School of Medicine Neurons R Us Core Facility (RRID:SCR_022421) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/OCRCBioTrust/

Provides specimens including gynecologic cancer specimens such as fresh and frozen tissues, plasma, serum, peripheral blood mononuclear cells, blood, formalin fixed paraffin embedded (FFPE) samples, and Tissue Microarrays (TMAs). All samples collected have clinical annotation including demographic patient profiles, pathological and clinical notations, treatment history, and detail disease information, etc. We are building and maintaining centralized research database according to HIPPA specifications and Penn IRB standards.

Proper citation: University of Pennsylvania Perelman School of Medicine Ovarian Cancer Research Center Tumor BioTrust Collection Core Facility (RRID:SCR_022387) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/NBTC.html

Core provides equipment and services to investigate behavior phenotypes of models related to neurological and other disorders. Core is utilized by scientists across disciplines that are interested in behavioral consequences of unique physiological disruptions (e.g., metabolic, drugs etc.). Provides assessment of many domains of behavior including sensory, motor, social, communication, affect related behaviors and learning and memory. NTC was established in 2012 through generous startup funds from the Penn School of Medicine, the Institute for Translational Medicine and Therapeutics (ITMAT), Center for Sleep and Circadian Neurobiology (CSCN) and Penn Medicine Neuroscience Center (PMNC).

Proper citation: University of Pennsylvania Perelman School of Medicine Neurobehavior Testing Core Facility (RRID:SCR_022386) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/saif-small-animal-imaging-facility

Core provides comprehensive suite of imaging modalities including magnetic resonance imaging (MRI), spectroscopy (MRS), optical imaging (including bioluminescence, fluorescence, and near-infrared imaging), computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and ultrasound (US). In addition, dedicated housing is available for mice and rats undergoing longitudinal imaging studies. Ancillary facilities and resources of SAIF are devoted to radiochemistry and image analysis.

Proper citation: University of Pennsylvania Perelman School of Medicine Small Animal Imaging Core Facility (RRID:SCR_022385) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/genomic-analysis-core/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 8th,2024. Facility offers sequencing services on three platforms, gold standard Sanger sequencing on ABI capillary sequencers, next generation sequencing (NGS) on Ion Torrent PGM and S5 and, Illumina MiSeq along with experimental design and data analysis.NGS service includes library preparation for multiple applications including targeted sequencing, RNA-Seq and Exome-Seq. Capillary sequencers also enable microsatellite genotyping and fragment analysis for VNTR, SNaPshot and Human Cell Line Authentication. Molecular biological services include PCR, cloning, subcloning, mutagenesis, construct preparation and, plasmid DNA preps at different scales.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Genomic Analysis DNA Sequencing Core Facility (RRID:SCR_022383) Copy   

•   Source: SciCrunch Registry