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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.jhugicc.org/GIConteCenter/pages/cores/proteomicsCore.html
Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Proteomics Core (RRID:SCR_015597) Copy
http://www.norc.uab.edu/corefacilities/physicalactivity
Core that provides physical activity services and consultation for UAB investigators. Services include aerobic fitness tests, supervised resistance training, submaximal ease/economy locomotion tests, and strength and functional tests, with respective measurements taken.
Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Physical Activity Core (RRID:SCR_015474) Copy
Core that designs, validates, and disseminates protocols for rodent urinary function testing. It also provides urinary function testing services, expertise, laboratory space, vivarium, and equipment for complete mouse urinary function testing.
Proper citation: O'Brien Center for Benign Urologic Research at University of Wisconsin-Madision and University of Massachusetts-Boston Rodent Urinary Function Testing Core (RRID:SCR_015477) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/imagingCore.html
Core facility that provides state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Image Core (RRID:SCR_015593) Copy
https://hddc.hms.harvard.edu/bio-repository-and-data-registry-human-material
Core facility that supports basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. It also aims to to forge connections and support collaboration between HDDC Clinical Associates and Members, support a well-organized infrastructure for acquisition and storage of clinical samples, and provide professional support in biostatistics and study design to HDDC members and Clinical Associates.
Proper citation: Harvard Digestive Diseases Center Bio-Repository and Data Registry for Human Material (RRID:SCR_015590) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/integratedPhysiology.html
Core facility that provides Center investigators and their laboratories the tools and advice needed to establish and study mouse (including transgenic and knockout) and human (i.e. GI organoids) physiology of GI disease.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Integrated Physiology Core (RRID:SCR_015591) Copy
http://www.med.umich.edu/mgpc/cores/pil.htm
Core facility whose services include the following programs: Imaging Core Program, Proteomics Core Program, Protein Folding Core Program, and Consultation.
Proper citation: University of Michigan Center for Gastrointestinal Research Protein Localization, Identification and Folding Core (RRID:SCR_015609) Copy
http://www.med.umich.edu/mgpc/cores/maic.htm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 8,2025. Core whose services include consultation, Nucleic Acid Isolation, Microbiome (16S) Data Analysis, MiSeq-base 16S rRNA Gene Sequencing, Genomic/Metagenomic shotgun sequencing, Bacterial transcriptomics and metatranscriptomics, Multiplatform Metabolomic Profiling, Metabolomic sample preparation, and Germ-free & Gnotobiotic Mouse Facilities.
Proper citation: University of Michigan Center for Gastrointestinal Research Microbiome and Metabolomics Core (RRID:SCR_015611) Copy
http://cunorc.org/cores/energy-core/
Core facility for University of Colorado Anschutz Medical Campus Nutrition and Obesity Research Center. Provides support for measurement of components of energy balance and for assessing consequences of alterations in energy balance. Provides expertise and support for obesity and nutrition related basic, clinical, translational, and transdisciplinary research for NORC investigators and its affiliates. Provides services to assess body composition, bone density, physical fitness, and energy expenditure values in research participants.
Proper citation: University of Colorado Anschutz Medical Campus Nutrition and Obesity Research Center Energy Balance Assessment Core Facility (RRID:SCR_015914) Copy
https://sdrc.stanford.edu/sdrc-research-cores/dgac/home/
Core facility that offers library preparation and sequencing services on a variety of platforms - Illumina HiSeq 4000, MiSeq, HiSeq 2500 and PacBio Sequel - as well as bioinformatics analysis. It can sequence a variety of commercial sample preparation kits as well as custom workflows. DGAC provides access to high throughput sequencing and analysis to researchers at the Stanford Diabetes Research Center.
Proper citation: Stanford Diabetes Research Center Diabetes Genomics Analysis Core (RRID:SCR_016213) Copy
http://sph.unc.edu/norc/research-partnerships/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 23,2019. Center that provides bioinformatics and metabolomics support to UNC members for nutrition and obesity-related clinical and translational research.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Research Facilitation Program (RRID:SCR_015480) Copy
http://amp.pharm.mssm.edu/X2K/
Software tool to produce inferred networks of transcription factors, proteins, and kinases predicted to regulate the expression of the inputted gene list by combining transcription factor enrichment analysis, protein-protein interaction network expansion, with kinase enrichment analysis. It provides the results as tables and interactive vector graphic figures.
Proper citation: eXpression2Kinases (RRID:SCR_016307) Copy
http://cobre.pbrc.edu/cores/genomics/
Provides services which include Sanger and next-generation DNA sequencing,DNA fragment analysis,qualitative and quantitative analysis of DNA, protein, and RNA samples, quantitative PCR, microarray RNA labeling, hybridization, and scanning robotics,bioinformatics.Individual and small group training and consultation services are offered for sequence analysis, real-time PCR, next-generation sequencing and microarray analysis.
Proper citation: Louisiana State University Pennington Biomedical Research Center Genomics Core Facility (RRID:SCR_018675) Copy
UMass Metabolic Disease Research Center (MDRC), formerly the National Mouse Metabolic Phenotyping Center, is a core facility that performs standardized experiments using state-of-the-art equipment for the purpose of investigating transgenic mouse models of diabetes, obesity, and metabolic liver disease. Provides metabolic and functional characterization of mouse models of human diseases that are developed by academic and industry researchers in joint efforts to understand metabolic diseases and to identify new therapies.
Proper citation: University of Massachusetts Medical School Metabolic Disease Research Center Core Facility (RRID:SCR_018672) Copy
http://www.med.umich.edu/mgpc/cores/vivo.htm
Core facility that consists of the following 4 distinct programs: In Vivo Small Animal Studies Program, Organoid/Enteroid Modeling Program, Biospecimens Banking Service, and Clinical Design and Statistics.
Proper citation: University of Michigan Center for Gastrointestinal Research In Vivo Animal and Human Studies Core (RRID:SCR_015608) Copy
https://gataca.cchmc.org/gataca/gudmap
A database which can be used to search for genes critical for a variety of Genito-Urinary system functions and diseases.
Proper citation: GATACA GUDMAP Gene Explorer (RRID:SCR_014518) Copy
http://www.uchicagoddrcc.org/research-cores/tissue-and-cell-analysis-core
Core whose services include anatomic pathology review of human and experimental animal tissues as well as consultation in the best approaches for such analyses, cost-effective and high quality processing and staining of formalin-fixed paraffin-embedded tissues, and making collections of human tissue and imaging technologies available to researchers.
Proper citation: University of Chicago Digestive Diseases Research Core Center Tissue and Cell Imaging Core (RRID:SCR_015607) Copy
Program is performing deep phenotyping of human endocrine pancreas and its interaction with immune system to better understand cellular and molecular events that precede and lead to beta cell loss in Type-1 Diabetes (T1D) and islet dysfunction in Type-2 Diabetes (T2D).
Proper citation: HIRN Human Pancreas Analysis Program (RRID:SCR_016202) Copy
http://www.broadinstitute.org/pubs/MitoCarta/
Collection of genes encoding proteins with strong support of mitochondrial localization. Inventory of genes encoding mitochondrial-localized proteins and their expression across 14 mouse tissues. Database is based on human and mouse RefSeq proteins that are mapped to NCBI Gene loci. MitoCarta 2.0 inventory provides molecular framework for system-level analysis of mammalian mitochondria.
Proper citation: MitoCarta (RRID:SCR_018165) Copy
Web multi omics knowledgebase based upon public, manually curated transcriptomic and cistromic datasets involving genetic and small molecule manipulations of cellular receptors, enzymes and transcription factors. Integrated omics knowledgebase for mammalian cellular signaling pathways. Web browser interface was designed to accommodate numerous routine data mining strategies. Datasets are biocurated versions of publically archived datasets and are formatted according to recommendations of the FORCE11 Joint Declaration on Data Citation Principles73, and are made available under Creative Commons CC 3.0 BY license. Original datasets are available.
Proper citation: Signaling Pathways Project (RRID:SCR_018412) Copy
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