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https://www.lerner.ccf.org/cores/microbial-sequencing/
Core provides services, from DNA and RNA extraction from diverse sample types such as tissue, stool, and bacterial isolates to next-generation sequencing, including whole-genome sequencing, total RNA-seq, metatranscriptomics, and dual RNA-seq, along with expert bioinformatics support. Core expertise spans 16S rRNA amplicon sequencing, shotgun metagenomics, metatranscriptomics, meta-omics analysis of dual RNA-seq, and single-cell RNA-seq data. Core also assists with experimental design and power calculations to ensure statistically robust results, offering consultation at every stage, from experimental design to data interpretation and troubleshooting.
Proper citation: Cleveland Clinic Lerner Research Institute Microbial Sequencing and Analytics Core Facility (RRID:SCR_026609) Copy
Shared resource facility to provide researchers access to resources, including state of the art instrumentation and technical support, to conduct biomedical research. Provides access to light microscopes (confocal, mesoscale lightsheet, and Super Resolution), as well as software for 3D and 4D analysis.
Proper citation: University of California at Irvine Optical Biology Core Facility (RRID:SCR_026614) Copy
https://genomics.uci.edu/about-us/
Core provides services ranging from DNA/RNA QC analysis, library construction and sequencing on various platforms. Offers several sequencing platforms from Illumina’s MiSeq and NovaSeq to PacBio’s Sequel II System.
Proper citation: University of California at Irvine Genomics Research and Technology Hub Core Facility (RRID:SCR_026615) Copy
Core provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners.
Proper citation: University of Michigan Medical School BRCF Epigenomics Core Facility (RRID:SCR_026720) Copy
Facility provides equipment for flow cytometric analysis and full-service cell sorting, as well as flow cytometry training and education for new users.
Proper citation: University of British Columbia BCCHR Flow Cytometry Core Facility (RRID:SCR_026601) Copy
Offers microscopy instrumentation and services. Offers support and training on variety of high-end instrumentation and advanced methodologies for both light and electron microscopy, sample preparation services for electron microscopy, training and assistance with image analysis. Provides support across variety of open-source and commercial image analysis software packages.
Proper citation: University of Michigan Medical School BRCF Microscopy Core Facility (RRID:SCR_026722) Copy
Offers full-service sample analysis to measure concentrations of small molecules in biological samples. Services include targeted and untargeted metabolomic screening, method development to explore novel metabolic pathways and systems. Staff helps with interpretation and visualization of your data, and the preparation of grants, proposals, and manuscripts.
Proper citation: University of Michigan Medical School BRCF Metabolomics Core Facility (RRID:SCR_026721) Copy
https://biointerfaces.umich.edu/facility/nanotechnicum/
Nanotechnicum is a Biointerfaces Institute core facility providing Nanoparticle Size analysis and Zeta Potential characterization, Chiral materials spectroscopy, Material Pore Size and Porosity characterization, Materials Thermal analysis, and Biomolecular Binding characterization instrumentation and services. The Biointerfaces Institute offers instrumentation to the University of Michigan’s research community, fellow academic institutions, and industry.
Proper citation: University of Michigan Biointerfaces Institute Nanotechnicum Core Facility (RRID:SCR_026717) Copy
Provides full-service consultation, sample processing and results. After running your samples, we will process your data using Mestranova and give you access to the raw data via email or Dropbox.
Proper citation: University of Michigan College of Pharmacy Biochemical Nuclear Magnetic Resonance Lab Core Facility (RRID:SCR_026716) Copy
https://sites.lsa.umich.edu/bio-mass-spec/
Facility provides specialized MS services. The major areas of focus of the lab are Analysis of intact proteins, multi-protein complexes, and protein structure; Identification and purification of compounds from complex mixtures coupled with quantitative analysis.; Purification using mass directed autopurification liquid chromatography. Users can be trained on the instruments for walk-up use or samples can be submitted for analysis.
Proper citation: University of Michigan Biological Mass Spectrometry Core Facility (RRID:SCR_026718) Copy
https://www.benaroyaresearch.org/our-research/core-labs/genomics-core
Core provides services for genomics analysis, from sample processing through data generation. Available technologies focus on Illumina RNA and DNA sequencing. RNA-seq can be performed from a variety of sample types, including purified total RNA, cell populations (including low input samples of 50-1000 cells), or single cells (either plate-sorted rare populations or high-throughput 10x single-cell analyses). DNA-seq pipelines can also be performed, including bulk CUT and Tag/CUT and RUN, and ATAC-seq and single cell ATACseq and multiome capture. Custom prepared libraries can also be submitted for sequencing. Core laboratory houses Illumina sequencers, NextSeq2000 instruments and Miseq, plus 10x Chromium X and 10x CytAssist. Additional equipment includes ThermoFisher Kingfisher Flex, for extracting nucleic acid from variety of sample types using magnetic bead technology with throughput of up to 96 samples. Qiagen QIAcube Connect instruments automate extraction of nucleic acid using spin column technology. Ancillary equipment for sample processing includes Formulatrix Mantis Liquid Handler, Agilent TapeStation 4200 and Tecan NanoQuant.
Proper citation: Benaroya Research Institute Genomics Core Facility (RRID:SCR_026658) Copy
https://cvm.ncsu.edu/research/labs/flow-cytometry-and-cell-sorting/
Core provides flow cytometry services. Staff members will help with experimental design, instrument training, sample acquisition, data analysis with software provided, and conventional/spectral cell sorting.
Proper citation: North Carolina State University College of Veterinary Medicine Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_026657) Copy
https://sites.lsa.umich.edu/emal/
EMAL is part of University of Michigan’s School of Earth and Environmental Sciences. Houses CAMECA SX100 electron microprobes, Rigaku X-ray diffractometers, and JEOL JSM-7800FLV field-emission scanning electron microscope. These instruments are used by researchers for chemical and structural characterization of solid materials.
Proper citation: University of Michigan Electron Microbeam Analysis Core Facility (RRID:SCR_026750) Copy
Simulation lab that is designed as home. Provides space to researchers who want to observe participant behavior in more realistic environment. Offers environment that feels authentic and natural to human condition.
Proper citation: University of Michigan HomeLab Core Facility (RRID:SCR_026753) Copy
https://medicine.umich.edu/dept/radiology/research/radiology-3t-research-mri-lab
Human Research 3 Tesla Magnetic Resonance Imaging provides high quality anatomic and advanced MR imaging services for IRB-approved research studies and clinical trials with funds allocated for non-standard-of-care research MRI scans.
Proper citation: University of Michigan Human Research 3 Tesla Magnetic Resonance Imaging Core Facility (RRID:SCR_026754) Copy
https://dent.umich.edu/research/molecular-biology-core
Molecular Biology Core (MBC) is School of Dentistry core and provides real-time quantitative PCR service (ABI ViiA7, ABI-7500 instruments), methodology, technique and experiment design consultation, analytical software training, data analysis, statistics and result interpretation assistance
Proper citation: University of Michigan Dental School Molecular Biology Core Facility (RRID:SCR_026748) Copy
https://dent.umich.edu/research/core-facilities/microct-core
Core offers services and instruments. Offers Scanco μCT 100 micro-computed tomography system which provides high resolution scans of radio opaque specimens such as bone, contrasted soft tissue, bio materials, etc.
Proper citation: University of Michigan Dental School MicroCT Core Facility (RRID:SCR_026747) Copy
https://www.pathology.med.umich.edu/digital-pathology/services
Performs scanning on per-request basis; maintains secure database of scanned images and associated metadata; instructs and provides technical support to faculty and staff for DP use; supports of live-view microscopy for frozen sections and testing and validation of new whole-slide imaging solutions.
Proper citation: University of Michigan Digital Pathology Core Facility (RRID:SCR_026749) Copy
https://sites.lsa.umich.edu/isopaleolab/facilities/
Core specializes in precise measurements of rare isotopologues such as “clumped” isotopes of carbonate and CO2 and triple oxygen isotope distributions in waters, carbonates, phosphates and recently organics. Houses Nu Perspective IRMS mass spectrometers, EuroVector EA3000 and HT-PyrOH, NuCarb device for traditional carbon and oxygen isotopes, Thermo Fisher ISQ 7000 GC-MS, fully automated clumped isotope preparation line, semi-automated triple oxygen isotope preparation line, manual water fluorination line, multi-purpose vacuum extraction line, and ovens, balances, glassware, fume hoods, and other equipment used in experiments and sample preparation.
Proper citation: University of Michigan Isopaleo Lab Core Facility (RRID:SCR_026763) Copy
Research facility dedicated to the study and testing of various marine and hydrodynamic phenomena. It is part of the Department of Naval Architecture and Marine Engineering at the University of Michigan. Conducts research and experiments related to fluid dynamics, ship design, offshore engineering, and other areas relevant to marine and naval architecture.
Proper citation: University of Michigan Marine Hydrodynamics Lab Core Facility (RRID:SCR_026765) Copy
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