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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.med.upenn.edu/fmch/mixed-methods-research-lab
Fosters the use of qualitative and mixed methods research methodologies with focus on integrating key stakeholder perspectives and goals into research designs. Collaborates with investigators to address timely, pressing questions across diverse disciplines and works with investigators to provide conceptual as well as technical support for broad research programs, including clinical, community based, and implementation science research questions.
Proper citation: University of Pennsylvania Perelman School of Medicine Mixed Methods Research Lab Core Facility (RRID:SCR_022418) Copy
https://www.research.chop.edu/penn-microbial-culture-and-metabolomics-core
Provides equipment for aerobic and anaerobic culture of microbial species in both batch and continuous systems, as well as targeted metabolomic services of amino, bile, and short chain fatty acids. Offers training and usage for culture equipment; consultation regarding experimental design, and; anaerobic culture services. Examples of culture studies include isolation of microbial taxa from mammalian samples; interrogation of the physiology of microbial strains under different conditions (e.g., anaerobic/microaerobic/aerobic, differing nutrient limitations) using isolated strains or strains obtained from culture collections (another service offered by the core); co-culturing of defined microbial consortia to investigate microbe-microbe interactions, and; preparation of microbial products (live bacteria, heat-killed bacteria, bacterial supernatants) from single or defined-mixed microbial cultures for use in mammalian cell culture and/or animal model systems.
Proper citation: University of Pennsylvania Perelman School of Medicine Microbial Culture and Metabolomics Core Facility (RRID:SCR_022417) Copy
https://www.med.upenn.edu/jf/bsbcore/index.html
Provides unique equipment and expertise to facilitate modern biophysical characterization and structural analysis of proteins and other biomolecules., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: University of Pennsylvania Perelman School of Medicine Johnson Foundation Biophysical and Structural Biology Core Facility (RRID:SCR_022414) Copy
https://www.itmat.upenn.edu/sdab/
Core works with existing resources to provide targeted study design and biostatistics support to ITMAT/CTSA investigators.Services include protocol review, study design, proposal development, and performance of simple to potentially substantial complex analyses. SDAB integrates support available with HUP and CHOP Center for Human Phenomic Science (CHPSs), expertise and resources of faculty in Center for Clinical Epidemiology and Biostatistics / Department of Biostatistics and Epidemiology (CCEB/DBE), Biostatistics Analysis Center (BAC), and Biostatistics and Data Management Core (BDMC) at CHOP.
Proper citation: University of Pennsylvania Perelman School of Medicine ITMAT Study Design and Biostatistics Core Facility (RRID:SCR_022413) Copy
https://med-upenn.corefacilities.org/sc/4405/crispr-cas9-mouse-targeting-core/?tab=about
Core facilitates use of CRISPR/Cas9 genome editing technology to generate novel mouse genetic tools.
Proper citation: University of Pennsylvania Perelman School of Medicine CRISPR Cas9 Mouse Targeting Core Facility (RRID:SCR_022378) Copy
https://www.sbpdiscovery.org/biomedical-research/shared-resources/proteomics
Facility provides mass spectrometry based proteomics services with methods tailored to needs of scientific investigators for routine mass spectrometric analysis of peptides and proteins, identification of novel proteins, characterization of post translational modifications, and quantitative proteomics analysis of simple to complex biological samples. Core identifies, validates and develops new methods designed for characterization and identification of biologically important proteins. Supports users with software applications and development, data analysis and experimental design of proteomics studies. Expands its capabilities in large scale differential proteomics analysis and phosphoproteomics for unbiased discovery of potential biomarkers and mapping protein profiles.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Proteomics Core Facility (RRID:SCR_022225) Copy
Services include RNA quality control, amplification and labeling, array hybridization, scanning and data analysis, assisting customers in design and performance of microarray experiments, using Agilent (pre-made and custom) and Affymetrix arrays. Provides support for quantitation and quality assessment of DNA, RNA and protein on Agilent 2100 Bioanalyzer. Provides training and support for Agilent and Affymetrix Hybridization oven users. Provides support for microarray scanning and for data analysis with variety of software packages for both Agilent and Affymetrix platforms.Quantity and quality of your RNA, DNA, proteins and cells are determined with help of Agilent 2100 Bioanalyzer.
Proper citation: University of South Carolina at Columbia College of Pharmacy Microarray Core Facility (RRID:SCR_022211) Copy
Core mass spectrometry facility located in Department of Chemistry, University of Toronto, which houses several mass spectrometers. Services include:High resolution, accurate mass determinations of small molecules via EI, ESI and DART ionization;Mass determinations of intact peptides and proteins via ESI-QTOF-MS and MALDI-MS; HPLC-MS/MS analysis of protein digests via ESI-QTOF-MS; Quantitative analysis via HPLC-MS/MS using QqQ instrumentation.
Proper citation: University of Toronto Advanced Instrumentation for Molecular Structure Mass Spectrometry Laboratory Core Facility (RRID:SCR_022210) Copy
https://micron.hms.harvard.edu/
Light microscopy core is open to HMS researchers, including Affiliated hospitals. Supports imaging modalities ranging from wide field, TIRF, spinning disk and single point scanning confocal, multiphoton, FLIM and supper resolution. Microscopes are embedded within Departments of Microbiology, Immunology, and Genetics, housed in five microscope rooms on five floors of NRB and HIM.
Proper citation: Harvard Medical School Microscopy Resources On the North Quad Core Facility (RRID:SCR_022209) Copy
https://www.biomedicas.unam.mx/servicios/unidad-de-microscopia/
Core is specialized in stereology techniques, live cell imaging, CLSM (confocal microscopy), and STORM. Provided instruments include CONFOCAL microscopes Zeiss LSM 5 Pascal, Olympus BX51-WI,Olympus IX71 inverted microscope, Nikon Labophot-2 microscope,Nikon Optiphot 2 microscope.
Proper citation: National Autonomous University of Mexico Microscopy Core Facility (RRID:SCR_022204) Copy
Core produces mice and rats for biomedical research. Provides services for customers are researchers from Unicamp and other Institutions from Brazil.
Proper citation: State University of Campinas Multidisciplinary Center for Biological Investigantion on Laboratory Animals Science Core Facility (RRID:SCR_022203) Copy
https://vtpb.tamu.edu/flow-cytometry/
Provides flow cytometry experimental design, data collection, data analysis and cell sorting services; training for flow cytometers, imaging flow cytometer, and data analysis using IDEAS and FlowJo software;staff assisted flow cytometry and imaging flow cytometry data acquisition, cell sorting, and data analysis, experimental design and consultation services. FCF currently has Beckman Coulter Moflo Astrios cell sorter, Luminex/Amnis Image Stream X Mark II, Luminex/Amnis Cell Stream, and Becton Dickinson Accuri C6 flow cytometer. Astrios cell sorter is housed in ClassII BSC and has 3 lasers (405nm, 488nm, 642nm) and 11 detectors and can sort up to 6 populations simultaneously. Image Stream X Mark II is equipped with 20x, 40x, 60x objectives, 4 lasers (405nm, 488nm, 561nm, 642nm), 10 detection channels, EV mode for small particle detection, and an autosampler.Cell Stream is equipped with 3 lasers (405nm, 488nm, 642nm), 13 detection channels, EV mode for small particle detection, and autosampler. Accuri C6 is equipped with 2 lasers (488nm, 642nm), and 4 detection channels.
Proper citation: Texas A and M University College of Veterinary Medicine and Biomedical Sciences Flow Cytometry Core Facility (RRID:SCR_022169) Copy
https://cancer.dartmouth.edu/scientists-researchers/clinical-pharmacology
Supports Dartmouth Cancer Center investigators in design, performance, data analysis, and interpretation of pharmacology objectives in preclinical, clinical and epidemiological studies.
Proper citation: Dartmouth College Clinical Pharmacology Shared Resource Core Facility (RRID:SCR_000873) Copy
https://www.biotech.cornell.edu/core-facilities-brc/facilities/genomics-innovation-hub
Core complements services provided by BRC Genomics Facility.Working on collaborative model, protocol and method development by early adopters pave the way for larger scale production services.
Proper citation: Cornell University BRC Genomics Innovation Hub Core Facility (RRID:SCR_022547) Copy
http://www.hiim.unizg.hr/index.php/institut/glowlab
Multimodal preclinical in vivo imaging facility for small laboratory animals such as mice and rats. Expertise is in brain research, however it is possible to provide imaging services on any part of or on animal.Instruments include magnetic resonance imager (Bruker BioSpec 70/20 USR) and optical bioluminescence/fluorescence imager (Perkin Elmer IVIS Spectrum), fully equipped with anesthesia delivery and physiological monitoring/control system.Imaging unit is complemented by cell culture laboratory and small animal surgery room, allowing to set up and perform entire experimental protocols as needed. Provides longitudinal imaging services owing to animal housing unit within same space, equipped with individually ventilated cages for both rats and mice (Tecniplast Green line and Emmerald line). Home cage monitoring is also possible for mice as an additional service with our Tecniplast DVC cages.
Proper citation: University of Zagreb School of Medicine Laboratory for Regenerative Neuroscience Core Facility (RRID:SCR_022701) Copy
https://www.dental.upenn.edu/research/core-facilities/
Provides Becton Dickinson LSR II flow cytometer equipped with four lasers.Blue laser can be used to detect forward and side scatter and 4 colors (eg., FITC/Alexa 488, PE, PerCP-CY55, PE-CY7), red laser can be used to detect 2 colors (e.g., APC and APC-CY7), violet laser can be used to detect 2 colors (e.g., Pacific blue, Am cyan) and a UV laser which can also be used to detect 2 colors (e.g., INDO1 blue, Indo1-violet/DAPI). The instrument is located in Room 330 in the Levy Building (240 South 40th Street).
Proper citation: University of Pennsylvania Penn Dental Medicine Flow Cytometry Core Facility (RRID:SCR_022443) Copy
https://flowcytometrycore.vai.org/
Core provides cell analysis and sorting services. Instruments include Cytek Aurora, Beckman Coulter CytoFLEX S, Thermo Fisher Attune CytPix, SONY MA900, and BD FACSSymphony S6.
Proper citation: Van Andel Institute Flow Cytometry Core Facility (RRID:SCR_022685) Copy
https://drexel.edu/core-facilities/facilities/material-characterization/
Facility provides technical expertise and instrumentation including nanoscience and engineering, polymer research, biomedical engineering, and chemistry and physics of solid materials.Houses electron microscopes, X-ray diffractometers, X-ray photoelectron spectrometer and suite of sample preparation tools. Staff members provide expert consultation, training and assistance to MCC users. Core is involved in teaching both undergraduate and graduate level courses in Materials Science and Engineering, Mechanical Engineering and Mechanics, Biomedical Engineering, and Biology. Trained and certified users are welcome to work independently on our instruments.
Proper citation: Drexel University Materials Characterization Core Facility (RRID:SCR_022684) Copy
https://www.unmc.edu/physiology/research/echo-facility.html
Preclinical ultrasound imaging. Provided instruments include Vevo 3100, Vevo 3100 LAZR-X, Perkin Elmer Vega.
Proper citation: University of Nebraska Medical Center Echocardiography Imaging Core Facility (RRID:SCR_022683) Copy
https://www.vet.upenn.edu/research/core-resources-facilities/referral-center-for-animal-models
Core mission is to discover, create, characterize, treat, and share naturally occurring hereditary disorders in dogs and cats that are orthologous to those found in human patients.�Provides expertise in discovering, characterizing, and developing therapies for genetic disease in dogs and cats, which serve as models of same diseases that occur in children.�Specializes in molecular discovery of mutations, clinical phenotyping, biochemical and histological characterization, development of therapies which are translatable to human patients and preclinical trials in animal models of human disease.�
Proper citation: University of Pennsylvania Penn Vet Referral Center for Animal Models of Human Genetic Disease Core Facility (RRID:SCR_022440) Copy
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