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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ComplexHeatmap
 
Resource Report
Resource Website
1000+ mentions
ComplexHeatmap (RRID:SCR_017270) data processing software, software application, data visualization software, data analysis software, software resource Software package to arrange multiple heatmaps and support various annotation graphics. Used to visualize associations between different sources of data sets and to reveal potential patterns. arrange, multiple, heatmap, visualize, data, pattern, genomic, dataset, bio.tools is listed by: Debian
is listed by: bio.tools
German Cancer Research Center-Heidelberg Center for Personalized Oncology ;
BMBF
PMID:27207943 Free, Available for download, Freely available biotools:complexheatmap https://github.com/jokergoo/ComplexHeatmap, https://bio.tools/complexheatmap SCR_017270 2026-08-05 10:46:45 3266
SWISS-MODEL
 
Resource Report
Resource Website
1000+ mentions
SWISS-MODEL (RRID:SCR_018123) data or information resource, data access protocol, software resource, service resource, web service Software tool as fully automated protein structure homology modeling server, accessible via ExPASy web server, or from program DeepView Swiss Pdb-Viewer. Structural bioinformatics web-server dedicated to homology modeling of 3D protein structures. Used to make protein modelling accessible to all biochemists and molecular biologists. 3D protein structure, homology modeling server, protein modeling, structural bioinformatics, automated comparative modeling, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: ExPASy Bioinformatics Resource Portal
is related to: Swiss-PdbViewerDeepViewv4.0
has parent organization: University of Basel; Basel; Switzerland
provides: SWISS-MODEL Repository
PMID:12824332 Free, Freely available biotools:swiss-model_workspace, biotools:swiss_model https://bio.tools/swiss_model, https://bio.tools/swiss-model_workspace SCR_018123 2026-08-05 10:46:56 2796
SIGNOR
 
Resource Report
Resource Website
10+ mentions
SIGNOR (RRID:SCR_018485) data or information resource, data repository, database, storage service resource, service resource Software application to organize and store in structured format signaling information published in scientific literature. Information is stored as binary causative relationships between biological entities and can be represented graphically as activity flow. Each relationship is linked to literature reporting experimental evidence. Each node is annotated with chemical inhibitors that modulate its activity. Signaling information is mapped to human proteome. SIGNOR 2.0 stores manually annotated causal relationships between proteins and other biologically relevant entities including chemicals, phenotypes, complexes, etc with compliance to FAIR data principles. Signal transduction data, signaling information, published data collection, activity flow, chemical inhibitor, human proteome, manually annotated data, protein, protein relationship, FAIR data, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: REDIportal
Italian Association for Cancer Research ;
ELIXIR-IIB ;
Italian Node of the European ELIXIR infrastructure ;
EMBL-EBI
PMID:31665520 Free, Available for download, Freely available biotools:signor https://bio.tools/signor SCR_018485 SIGnaling Network Open Resource, SIGNOR 2.0 2026-08-05 10:47:01 40
EvidenceFinder
 
Resource Report
Resource Website
1+ mentions
EvidenceFinder (RRID:SCR_013764) software resource, web application A web application to assist in the identification of articles and research related to literature search terms. The search covers full text articles in the Europe PMC repository. Relevant papers are suggested to users based on the scientific term searched and the selection of questions, generated by the application, relevant to term searched. web application, software resource, literature search, bio.tools is used by: Europe PubMed Central
is listed by: Connected Researchers
is listed by: Debian
is listed by: bio.tools
is related to: Connected Researchers
is related to: Europe PubMed Central
has parent organization: Europe PubMed Central
Wellcome Trust 098231 DOI:10.1093/nar/gku1061 Free, Public biotools:evidence_finder https://bio.tools/evidence_finder SCR_013764 2026-08-05 10:46:03 3
ToppCluster
 
Resource Report
Resource Website
100+ mentions
ToppCluster (RRID:SCR_001503) ToppCluster data analysis service, resource, production service resource, service resource, analysis service resource A tool for performing multi-cluster gene functional enrichment analyses on large scale data (microarray experiments with many time-points, cell-types, tissue-types, etc.). It facilitates co-analysis of multiple gene lists and yields as output a rich functional map showing the shared and list-specific functional features. The output can be visualized in tabular, heatmap or network formats using built-in options as well as third-party software. It uses the hypergeometric test to obtain functional enrichment achieved via the gene list enrichment analysis option available in ToppGene. term enrichment, gene, analysis, gene enrichment analysis, connectivity, heatmap, ortholog, microarray, function, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: GenitoUrinary Development Molecular Anatomy Project
is related to: ToppGene Suite
NIDDK 1U01DK70219;
NIDDK P30DK078392;
NCRR U54 RR025216;
NIDCR U01DE020049
PMID:20484371 Free OMICS_02225, nlx_152801, biotools:toppcluster https://bio.tools/toppcluster SCR_001503 ToppCluster: A multiple gene list feature analyzer for the dissection of biological systems 2026-08-05 10:43:22 144
StatAlign
 
Resource Report
Resource Website
1+ mentions
StatAlign (RRID:SCR_001892) data processing software, software application, sequence analysis software, data analysis software, software resource Software package for Bayesian analysis of protein, DNA and RNA sequences. It utilizes multiple alignments, phylogenetic trees and evolutionary parameters to quantify uncertainty in these analyses. It is written in Java. software package, bayesian, protein, dna, rna, sequencing, java, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
PMID:23335014 Free, Available for download, Freely available biotools:StatAlign, OMICS_03743 https://bio.tools/StatAlign SCR_001892 StatAlign 2.0 2026-08-05 10:43:29 1
FACTA+.
 
Resource Report
Resource Website
1+ mentions
FACTA+. (RRID:SCR_001767) FACTA+ data access protocol, service resource, software resource, web service Text mining tool to discover associations between biomedical concepts from MEDLINE articles. Use the service from your browser or via a Web Service. The whole MEDLINE corpus containing more than 20 million articles is indexed with an efficient text search engine, and it allows you to navigate such associations and their textual evidence in a highly interactive manner - the system accepts arbitrary query terms and displays relevant concepts immediately. A broad range of important biomedical concepts are covered by the combination of a machine learning-based term recognizer and large-scale dictionaries for genes, proteins, diseases, and chemical compounds. There is also a FACTA+ visualization service that can be found here: http://www.nactem.ac.uk/facta-visualizer/ text mining, gene, protein, disease, symptom, drug, enzyme, compound, biomedical, association, machine learning, chemical, text-mining software, bio.tools is listed by: OMICtools
is listed by: FORCE11
is listed by: bio.tools
is listed by: Debian
is related to: MEDLINE
has parent organization: National Centre for Text Mining
JISC PMID:18772154 Free, Freely available biotools:facta_plus, nif-0000-10272, OMICS_01181 http://refine1-nactem.mc.man.ac.uk/facta/, https://bio.tools/facta_plus SCR_001767 Finding Associated Concepts with Text Analysis 2026-08-05 10:43:30 2
FusionCatcher
 
Resource Report
Resource Website
1+ mentions
FusionCatcher (RRID:SCR_000060) data processing software, software application, sequence analysis software, data analysis software, software resource Software that searches for novel/known fusion genes, translocations, and chimeras in RNA-seq data (paired-end reads from Illumina NGS platforms like Solexa and HiSeq) from diseased samples. fusion gene, known fusion gene, translocation, chimera, rna-seq data, hiseq, solexa, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1101/011650 Free, Available for download, Freely available biotools:fusioncatcher, OMICS_01348 https://github.com/ndaniel/fusioncatcher/blob/master/doc/manual.md, https://bio.tools/fusioncatcher http://code.google.com/p/fusioncatcher/ SCR_000060 2026-08-05 10:43:06 7
Dissect
 
Resource Report
Resource Website
Dissect (RRID:SCR_000058) Dissect data processing software, image analysis software, software application, alignment software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software transcriptome-to-genome alignment tool, which can identify and characterize transcriptomic events such as duplications, inversions, rearrangements and fusions. Structural events containing transcripts, transcriptome-to-genome alignment, identify and characterize transcriptomic events, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Simon Fraser University; British Columbia; Canada
PMID:22689759 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01346, biotools:dissect https://bio.tools/dissect SCR_000058 Dissect: DIScovery of Structural Events Containing Transcripts, DIScovery of Structural Events Containing Transcripts 2026-08-05 10:43:06 0
cpnDB: A Chaperonin Database
 
Resource Report
Resource Website
1+ mentions
cpnDB: A Chaperonin Database (RRID:SCR_002263) cpnDB data or information resource, database, data analysis service, production service resource, service resource, analysis service resource A curated collection of chaperonin sequence data collected from public databases or generated by a network of collaborators exploiting the cpn60 target in clinical, phylogenetic and microbial ecology studies. The database contains all available sequences for both group I and group II chaperonins. Users can search the database by Chaperonin type, group (I or II), BLAST, or other options, and can also enter and analyze FASTA sequences. chaperonin sequence, microbial ecology, phylogenetics, chaperonin, plastid, mitochondria, cytoplasm, sequence, blast, fasta, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Canadian Biotechnology Strategy ;
National Research Council Genomics and Health Initiative
PMID:15289485 Free, Freely available biotools:cpndb, OMICS_01511, nif-0000-02694 https://bio.tools/cpndb http://www.cpndb.ca/cpnDB/home.php SCR_002263 2026-08-05 10:43:36 3
Predictions for Entire Proteomes
 
Resource Report
Resource Website
500+ mentions
Predictions for Entire Proteomes (RRID:SCR_002803) data processing software, web application, software application, data analysis software, sequence analysis software, software resource Web application for sequence analysis and the prediction of protein structure and function. The user interface intakes protein sequences or alignments and returned multiple sequence alignments, motifs, and nuclear localization signals., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026. sequence analysis database, protein structure prediction, protein structure, protein function, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: Columbia University; New York; USA
BMBF PMID:24799431
DOI:10.1093/nar/gkh377
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00136, OMICS_07135, biotools:predictprotein https://bio.tools/predictprotein, https://sources.debian.org/src/predictprotein/ http://cubic.bioc.columbia.edu/pep/ SCR_002803 PredictProtein 2026-08-05 10:43:41 578
RegulonDB
 
Resource Report
Resource Website
100+ mentions
RegulonDB (RRID:SCR_003499) RegulonDB data or information resource, database Database on transcriptional regulation in Escherichia coli K-12 containing knowledge manually curated from original scientific publications, complemented with high throughput datasets and comprehensive computational predictions. Graphic and text-integrated environment with friendly navigation where regulatory information is always at hand. They provide integrated views to understand as well as organized knowledge in computable form. Users may submit data to make it publicly available. transcription, gene regulation, operon, bacteria, evolutionary conservation, regulatory phrase, transcriptional regulation, transcriptional regulatory network, bio.tools, FASEB list is listed by: OMICtools
is listed by: 3DVC
is listed by: bio.tools
is listed by: Debian
has parent organization: National Autonomous University of Mexico; Mexico City; Mexico
NIGMS GM071962;
NIGMS GM077678;
Consejo Nacional de Ciencia y Tecnologia 103686;
Consejo Nacional de Ciencia y Tecnologia 179997;
Programa de Apoyo a Proyectos de Investigacion e Innovacion Tecnologica IN210810;
Programa de Apoyo a Proyectos de Investigacion e Innovacion Tecnologica IN209312
PMID:23203884 nif-0000-03399, OMICS_01868, biotools:regulondb https://bio.tools/regulondb SCR_003499 2026-08-05 10:43:51 148
ProteomeXchange
 
Resource Report
Resource Website
5000+ mentions
ProteomeXchange (RRID:SCR_004055) data or information resource, data repository, portal, consortium, catalog, database, organization portal, storage service resource, service resource A data repository for proteomic data sets. The ProteomeExchange consortium, as a whole, aims to provide a coordinated submission of MS proteomics data to the main existing proteomics repositories, as well as to encourage optimal data dissemination. ProteomeXchange provides access to a number of public databases, and users can access and submit data sets to the consortium's PRIDE database and PASSEL/PeptideAtlas. consortium, database, proteomics, MS proteomics, protein, mass spectrometry, bio.tools, FASEB list uses: Proteomics Identifications (PRIDE)
uses: PeptideAtlas
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: bio.tools
is listed by: Debian
is affiliated with: Omics Discovery Index
is related to: Proteomics Identifications (PRIDE)
is related to: PeptideAtlas
is related to: SIB Swiss Institute of Bioinformatics
is related to: Mass spectrometry Interactive Virtual Environment (MassIVE)
is related to: European Bioinformatics Institute
is related to: ProteomeTools
is related to: Integrated Proteome Resources
has parent organization: European Bioinformatics Institute
European Union 260558 Public, The community can contribute to this resource r3d100012122, nlx_158620, biotools:proteomexchange http://proteomecentral.proteomexchange.org, https://bio.tools/proteomexchange, https://doi.org/10.17616/R32D29 SCR_004055 , ProteomeXchange, Proteome Exchange 2026-08-05 10:43:58 5192
ngLOC
 
Resource Report
Resource Website
10+ mentions
ngLOC (RRID:SCR_003150) ngLOC software resource, data analysis service, production service resource, service resource, analysis service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 5, 2023.An n-gram-based Bayesian classifier that predicts subcellular localization of proteins both in prokaryotes and eukaryotes. The downloadable version of this software with source code is freely available for academic use under the GNU General Public License. subcellular localization, protein, eukaryote, prokaryote, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22780965
PMID:17472741
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01629, biotools:ngloc https://bio.tools/ngloc SCR_003150 ngLOC - A Bayesian method for predicting protein subcellular localization 2026-08-05 10:43:46 22
ImaGene
 
Resource Report
Resource Website
100+ mentions
ImaGene (RRID:SCR_002178) software resource, data processing software, software application, data analysis software Software tool as convolutional neural network to quantify natural selection from genomic data.Supervised machine learning algorithm to predict natural selection and estimate selection coefficients from population genomic data. Can be used to estimate any parameter of interest from evolutionary population genetics model., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. microarray analysis, machine vision, convolutional neural network, quantify natural selection, genomic data, population genomic data, evolutionary population, genetics model, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Imperial College London ;
Politecnico di Milano
PMID:31757205 THIS RESOURCE IS NO LONGER IN SERVICE biotools:ImaGene, OMICS_00841 https://github.com/mfumagalli/ImaGene, https://bio.tools/ImaGene http://www.biodiscovery.com/software/imagene/ SCR_002178 2026-08-05 10:43:34 405
QualitySNPng
 
Resource Report
Resource Website
1+ mentions
QualitySNPng (RRID:SCR_002479) data processing software, software application, data visualization software, standalone software, software resource Software for the detection and visualization of single nucleotide polymorphisms (SNPs) from next generation sequencing data that uses a haplotype-based strategy. single nucleotide polymorphism, haplotype strategy, next generation sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23632165 Free, Available for download, Freely available biotools:qualitysnpng, OMICS_00070 https://bio.tools/qualitysnpng SCR_002479 2026-08-05 10:43:39 6
SynergyFinder
 
Resource Report
Resource Website
500+ mentions
SynergyFinder (RRID:SCR_019318) data processing software, software application, data visualization software, software toolkit, software resource Software R package as efficient implementations for all popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of synergy scores as either two dimensional or three dimensional interaction surface over dose matrix. Used to calculate and visualize synergy scores for drug combinations. Synergy scores, drug combinations, popular synergy scoring models, dimensional interaction surface, dose matrix, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is related to: SynergyFinder web application
DOI:10.1007/978-1-4939-7493-1_17 Free, Available for download, Freely available biotools:synergyfinder https://bio.tools/synergyfinder SCR_019318 synergyfinder 2026-08-05 10:47:12 510
fgsea
 
Resource Report
Resource Website
100+ mentions
fgsea (RRID:SCR_020938) software resource, data processing software, software application, data analysis software Software R package for fast preranked gene set enrichment analysis. Allows to make more permutations and get more fine grained p-values, which allows to use accurate stantard approaches to multiple hypothesis correction. Gene set enrichment analysis, preranked gene set, multiple hypothesis correction, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
DOI:10.1101/060012 Free, Available for download, Freely available biotools:fgsea https://github.com/ctlab/fgsea/, https://bio.tools/fgsea SCR_020938 fast gene set enrichment analysis, Fast Gene Set Enrichment Analysis, FGSEA 2026-08-05 10:47:19 185
Omics Data Paper Generator
 
Resource Report
Resource Website
1+ mentions
Omics Data Paper Generator (RRID:SCR_019809) software development tool, data processing software, documentation generation software, data access protocol, software application, software resource, workflow software, web service Software package for streamlined import of omics metadata from European Nucleotide Archive into OMICS Data Paper manuscript. Omics Data Paper R Shiny app demonstrates workflow for automatic import of ENA genomic metadata into omics data paper manuscript. Streamlined conversion of metadata into manuscript facilitates authoring of omics data papers, which allow omics dataset creators to receive credit for their work and to improve description and visibility of their datasets. Workflow, genomics, omics, FAIR data, data paper, G Power, European Nucleotide Archive, genomic metadata, omics data paper manuscript, streamlined conversion, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Shiny
Horizon 2020 764840 Free, Available for download, Freely available biotools:omics-data-paper-shinyapp-golem https://mdmtrv.shinyapps.io/Omics_data_paper/, https://bio.tools/omics-data-paper-shinyapp-golem SCR_019809 omicsdatapaper 2026-08-05 10:47:14 1
epitopepredict
 
Resource Report
Resource Website
1+ mentions
epitopepredict (RRID:SCR_019221) software application, simulation software, software resource Open source software tool as programmatic framework and command line tool designed to aid process of MHC binding prediction. Provides access to multiple binding prediction algorithms under single interface and scales for whole genomes using multiple target MHC alleles.Software should be run on Linux operating system. Ubuntu is recommended but most major distributions will be fine. Windows is not supported. Protein sequence, MHC binding prediction, whole genomes, multiple target MHC allele, epitope prediction, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:epitopepredict https://epitopepredict.readthedocs.io/en/latest/, https://bio.tools/epitopepredict SCR_019221 2026-08-05 10:47:12 2

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