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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://github.com/biocore/pynast
Software tool for aligning sequences to template alignment.
Proper citation: pynast (RRID:SCR_024189) Copy
http://www.bioinformatics.org/patristic/
Software Java program for calculating patristic distances and graphically comparing the components of genetic change.
Proper citation: Patristic (RRID:SCR_024154) Copy
https://docs.igdiscover.se/en/stable/
Software to analyze antibody repertoires and discover new V genes from high-throughput sequencing reads.Heavy chains, kappa and lambda light chains are supported (to discover VH, VK and VL genes)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: IgDiscover (RRID:SCR_024037) Copy
https://data.broadinstitute.org/alkesgroup/BOLT-LMM/
Software statistical tool for identifying genetic associations. Used for genome wide association studies in large cohorts.
Proper citation: BOLT-LMM (RRID:SCR_023978) Copy
https://quint-workflow.readthedocs.io/en/latest/QUINTintro.html
Software workflow includes suite of various software to form analysis pipeline of atlas-based quantifuication of labbeled features in histological images from mouse or rat brain. This workflow also suggests and explains with instructional videos the way these software work together. Used for quantification and spatial analysis of labelling in series of rodent brain section images based on available 3D reference atlases.
Proper citation: QUINT (RRID:SCR_023856) Copy
Open access integrated research platform, which links scientists, shared data, and analysis tools to accelerate Alzheimer’s disease research, disease preventions, treatments and cure. Unites diverse and geographically distributed network of data partners to foster cohort discovery, collaboration and sharing. Researchers can discover clinical, genetic, imaging and other data collected across many independent studies.
Proper citation: Global Alzheimers Association Interaction Network (RRID:SCR_023699) Copy
https://github.com/brainglobe/brainreg-segment
Software tool for manual segmentation of regions/objects within the brain. Brainreg-segment will only work if the user registers their data with brainreg first. Used for segmentation of 3D shapes in common anatomical space.
Proper citation: Brainreg-segment (RRID:SCR_023853) Copy
https://github.com/sanger-pathogens/iva
Software tool as de novo assembler designed to assemble virus genomes that have no repeat sequences,using Illumina read pairs sequenced from mixed populations at extremely high and variable depth.
Proper citation: IVA (RRID:SCR_024044) Copy
https://github.com/bioinfo-ut/PlasmidSeeker
Software tool as k-mer based program for identification of known plasmids from whole genome sequencing reads. Used for identification of known plasmids from bacterial whole genome sequencing reads.
Proper citation: PlasmidSeeker (RRID:SCR_024167) Copy
https://www.cancergenomeinterpreter.org/home
Platform that systematizes interpretation of cancer genomes and makes it automatic. Web tool to annotate genomic alterations and interpret their possible role in tumorigenesis and in response to anti cancer therapies. Used to support identification of tumor alterations that drive disease and/or which may be therapeutically actionable. Analyses mutations including single nucleotide changes and small insertions/deletions, copy number alterations including gene amplifications and deletions and translocations.
Proper citation: Cancer Genome Interpreter (RRID:SCR_023752) Copy
https://www.viewpoint.fr/product/zebrafish/cardiology/microzebralab
Software tool to extract cardiovascular parameters from transmitted light videos of zebrafish embryos or larvae. Used to investigate live and in non-invasive way scope of zebrafish larvae physiological parameters. Measures heartbeat and blood flow.
Proper citation: ViewPoint MicroZebraLab (RRID:SCR_023750) Copy
https://github.com/omnideconv/immunedeconv
Software R package for unified access to computational methods for estimating immune cell fractions from bulk RNA sequencing data.
Proper citation: Immunedeconv (RRID:SCR_023869) Copy
https://www.zeiss.com/microscopy/en/products/software/zeiss-zen-lite.html
Software tool for basic image acquisition and analysis. Zeiss ZEN microscopy software to control of axiocam microscope cameras, image transformation and measurements, image processing, image alignment for correlative microscopy, various visualization options.
Proper citation: Zeiss Zen Lite (RRID:SCR_023747) Copy
Software tool designed to simplify Multivariate analysis (correspondence analysis) of codon and amino acid usage. It also calculates standard indices of codon usage.
Proper citation: CodonW (RRID:SCR_023989) Copy
https://www.bibliometrix.org/home/
Software R package for comprehensive science mapping analysis. Used for quantitative research in scientometrics and bibliometrics that includes all main bibliometric methods of analysis.
Proper citation: bibliometrix (RRID:SCR_023744) Copy
https://www.cubi.bihealth.org/software/varfish/
Web application for quality control, filtering, prioritization, analysis, and user based annotation of DNA variant data with focus on rare disease genetics. Comprehensive DNA variant analysis for diagnostics and research.
Proper citation: VarFish (RRID:SCR_023710) Copy
https://github.com/mskcc/lohhla
Software tool to evaluate HLA loss using next-generation sequencing data. Computational tool to determine HLA allele-specific copy number from sequencing data.
Proper citation: LOHHLA (RRID:SCR_023690) Copy
https://pypi.org/project/oncoboxlib/
Software library to calculate Pathways Activation Levels. It takes file that contains gene symbols in HGNC format, their expression levels for one or more samples and calculates PAL values for each pathway in each sample.
Proper citation: oncoboxlib (RRID:SCR_023722) Copy
https://github.com/Martinsos/edlib
Software C/C++ (and Python) library for sequence alignment using edit (Levenshtein) distance.
Proper citation: Edlib (RRID:SCR_024078) Copy
https://github.com/GATB/MindTheGap
Software tool to perform detection and assembly of DNA insertion variants in NGS read datasets with respect to reference genome.Used to call insertions of any size, whether they are novel or duplicated, homozygous or heterozygous in the donor genome.
Proper citation: MindTheGap (RRID:SCR_024115) Copy
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