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https://www.cincinnatichildrens.org/research/cores/meg

Core facilitates study of normal and pathologic brain processes using magnetoencephalography.The purpose of the core is to make magnetoencephalography available to researchers across the institute.

Proper citation: Cincinnati Children's Hospital Magnetoencephalography Core Facility (RRID:SCR_022648) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dev-biology/core

Offers comprehensive CRISPR services to generate gene edited rodents and cells, and helps generate transgenic and chimeric mice via our microinjection service, cryopreserving unique mouse lines, and recovering them from liquid nitrogen storage via IVF and embryo transfer services.

Proper citation: Cincinnati Children's Hospital Transgenic Animal and Genome Editing Core Facility (RRID:SCR_022642) Copy   

•   Source: SciCrunch Registry

https://www.themiamiproject.org/research-resources/core-facilities/drug-discovery-core/

Core at Miami Project to Cure Paralysis leverages PerkinElmer Opera Phenix Plus high content screening system to provide assay development and phenotypic screening. Facility is also equipped with PerkinElmer Janus G3 liquid handler, featuring modular and variable dispense heads, to automate screening workflows and enhance throughput. Core supports phenotypic and target-based assays. Phenotypic assays range from 2D to 3D, widefield to confocal, and antibody to dye based. It collaborates with users to develop customized assays and analytical pipelines tailored to their specific needs. Current specializations include neurite tracing, lipid droplet quantification, cell viability, morphological and kinetic analyses, phagocytosis, cell marker detection, cell adhesion, among others.

Proper citation: Drug Discovery Core Facility (RRID:SCR_022542) Copy   

•   Source: SciCrunch Registry

https://www.mdc-berlin.de/genomics

Facility comprises Next Generation Sequencing, Single Cell Technologies and Data Management teams. Offers professional project counseling, library preparation, and sequence production support for Max Delbruck Center for Molecular Medicine and Berlin Institute of Health at Charite institutes in Berlin.

Proper citation: MDC and BIH Technology Platform Genomics Core Facility (RRID:SCR_022782) Copy   

•   Source: SciCrunch Registry

http://agl.tamu.edu/

Assists graduate students, staff and faculty launch, economize and expedite their research, especially when it involves DNA extraction and quality checks, targeted genotyping and DNA content analysis. Facilitates usage of complementary cores and assists with research planning and data analysis.AGL members have free lab access and reduced costs for services as well as one-on-one training and advising with AGL staff.

Proper citation: Texas A and M University AgriGenomics Laboratory Core Facility (RRID:SCR_022533) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/single-cell-genomics

Core to perform expression level analysis of thousands of genes in parallel.Uses RNA-Seq assays from Tecan Genomics, Takara and Illumina for samples with limited amounts of starting RNA. Microarray technology utilizing the Affymetrix GeneChip platform is also available.

Proper citation: Cincinnati Children's Hospital Single Cell Genomics Core Facility (RRID:SCR_022653) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/cardio-imaging

Offers imaging techniques using imaging and measurement tools. Offers consulting services ranging from educational seminars to assistance with grant and industry funding support.

Proper citation: Cincinnati Children's Hospital Cardiovascular Imaging Core Facility (RRID:SCR_022626) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/xd/research/research-cores/elemental-analysis/index.cfm

Provides highly sensitive elemental quantification, including sample preparation, data analysis, and experimental guidance, through Inductively Coupled Plasma Mass Spectrometry (ICP-MS) technology.

Proper citation: Oregon Health and Science University Elemental Analysis Core Facility (RRID:SCR_022746) Copy   

•   Source: SciCrunch Registry

https://aimi.psu.edu/

Connects industry members with Penn State research community of artificial intelligence and machine learning researchers and their students to solve real world problems and seize market opportunities.

Proper citation: Penn State University Center for Applications of Artificial Intelligence and Machine Learning to Industry Core Facility (RRID:SCR_022867) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/knight-cardiovascular-institute/center-radiochemistry-research

Provides access to tools for imaging with short lived radionuclides, data analysis and is integrated with campus centers SARIC and nuclear medicine clinic for quantitative imaging of these tracers in vivo that provides spatial and temporal data in order to improve our basic understanding of biochemical pathways, disease processes and help select personalized treatments that enhance clinical care. Highlights of our center include On-campus capacity to develop and produce radiopharmaceuticals to address specific research questions using in-vivo, real-time imaging;PET/CT, SPECT/CT (and soon PET/MRI) imaging capability to quantify organ perfusion, assess metabolic pathways, receptor function and density, and measure pharmacodynamics.Applications are directed toward range of models, ranging from small animals to non-human primates, to humans.

Proper citation: Oregon Health and Science University Center for Radiochemistry Research Core Facility (RRID:SCR_022745) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/biophysics-core

Core services including ensurance that purified proteins and other biomolecules of interest are uncompromised in terms of their structure and stability. Facilitates analyses of catalytic activities and functional interactions.Examines thermodynamic and kinetic parameters for association between proteins and small molecules.Facilitates hypothesis generation through coalescence of experimental data and computational modeling.Assists in setting up protein crystallization assays.

Proper citation: Oregon Health and Science University Biophysics Core Facility (RRID:SCR_022744) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/b/bmi/resource-service

Provides computational resources, services, and support to investigators including clinical research informatics, application and technology development, and bioinformatics analyses.

Proper citation: Cincinnati Children's Hospital Biomedical Informatics Core Facility (RRID:SCR_022622) Copy   

•   Source: SciCrunch Registry

https://www.dental.upenn.edu/research/core-facilities/tissue-processing-laboratory/

Laboratory is located in Room 429 of the Levy Building.Services include tissue processing; H&E staining, trichrome, and other staining; creation of frozen sections; and deparaffinization. Provides cryostat for use by investigators within Penn Dental Medicine; cryostat training is available for a fee. Investigators requiring the services of the Tissue Processing Laboratory should contact the facility to arrange a meeting to set up the appropriate protocols. Special handling, specimen orientation, and any unique aspects of the tissue being processed will be discussed at that time; in some instances, it may be advantageous for the investigator to be present initially when the specimens are being oriented in the hot paraffin prior to the actual sectioning.

Proper citation: University of Pennsylvania School of Dental Medicine Tissue Processing Laboratory Core Facility (RRID:SCR_022863) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/genomics/about/

Full service sequencing facility to assist with genetic and genomic research. Part of Integrated Genomics Cores. Offers comprehensive library services, NextGen sequencing and alternative technologies including long reads. Offers library preparations and multiple sequencing platforms including MiSeq, HiSeq, NovaSeq, NextSeq, BioNano, Oxford Nanopore. Services also include using techniques and data analyses via sister core BARC.

Proper citation: UNC School of Medicine Integrated Genomics Cores High Throughput Sequencing Core Facility (RRID:SCR_022620) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/xd/research/research-cores/bdp.cfm

Core provides designing studies and developing statistical analysis plans in clinical trials, clinical and community based intervention studies, laboratory experiments, and observational studies.Provides expertise in traditional and modern statistical methods.Can help with trial design and analysis, epidemiologic analysis, sample size and power, high dimensional data analysis, risk prediction, complex survey analysis, time-to-event and longitudinal models, and statistical simulation,data management and wrangling, analytic variable coding and data set creation, research database design, data visualization, manuscript preparation, statistical programming, and much more.

Proper citation: Oregon Health and Science University Biostatistics and Design Program Core Facility (RRID:SCR_022741) Copy   

•   Source: SciCrunch Registry

https://advancedimaging.vetmed.ucdavis.edu/

Fluorescence microscopy facility with two Leica confocal microscopes, one with superresolution capability,second with multi-photon imaging capability, and Zeiss Lightsheet microscope. Facility offers consultation, training, and support.

Proper citation: University of California at Davis Veterinary Medicine Advanced Imaging Core Facility (RRID:SCR_022862) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/c/critical/medialab

Develops high quality video and animation to enhance medical education.

Proper citation: Cincinnati Children's Hospital Critical Care Media Lab Core Facility (RRID:SCR_022629) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/viral-vector-core

Provides research grade retroviral, lentiviral and adeno associated virus vectors. Offers generation of stable producer lines, and non-GMP quality control testing including vector titer by functional assay FACS or PCR, endotoxin, mycoplasma, and USP sterility testing.Provides standard packaging plasmids, the investigator provides the viral vector to be used for the production run.

Proper citation: Cincinnati Children's Hospital Viral Vector Core Facility (RRID:SCR_022641) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/translational-trial-development-support-laboratory

Provides facilities and expertise to support clinical assay development from technology developed in academic laboratories.Provides assay development and testing support for early phase clinical trials with focus on cell and gene therapy.

Proper citation: Cincinnati Children's Hospital Translational Trial Development and Support Laboratory Core Facility (RRID:SCR_022640) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/service/p/pathology/mass-spectrometry

Provides analytical resource focusing on application of mass spectrometry and allied chromatographies to analysis of small molecules, generally of less than 1,000 daltons molecular weight, in complex clinical and biological samples.

Proper citation: Cincinnati Children's Hospital Mass Spectrometry Core Facility (RRID:SCR_022638) Copy   

•   Source: SciCrunch Registry