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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.mayo.edu/research/core-resources/antibody-hybridoma-core/overview
Core can generate custom monoclonal antibodies in mouse and hamster systems. Can also produce large amounts of antibodies (of all species) and recombinant proteins in-vitro. Purification is also available for various systems.
Proper citation: Mayo Clinic Antibody Hybridoma Core Facility (RRID:SCR_027544) Copy
Facility provides training and access to advanced light microscopy systems at an hourly rate. In addition, we are available to consult with and support users at every stage of a project including: experimental design, sample preparation, image acquisition, analysis, and data preparation.
Proper citation: University of Connecticut Advanced Light Microscopy Core Facility (RRID:SCR_027547) Copy
https://research.manchester.ac.uk/en/equipments/core-facility-for-advanced-metal-development
Core supports all processing of metal related activity and houses equipment in the areas of thermomechanical processing, additive manufacturing, mechanical testing (including testing under a variety of environments), thermomechanical simulation/testing and heat treatment.
Proper citation: University of Manchester Advanced Metal Development Core Facility (RRID:SCR_027557) Copy
https://nmrcore.uhnresearch.ca/
NMR Core Facility is equipped with NMR spectrometers allowing researchers to Characterize bio-molecular structures at the atomic resolution with exquisite details;Identify protein interactions with binding partners in order to understand their architecture;Study protein dynamic;Study protein post-translational modifications acting as molecular switches;Study structure-function relationships of biological proteins to gain insight into biological processes in relation to human disease;Screening of High-throughput drug-like leads for novel therapeutic targets;Study Metabolites of interest.Core facility houses high-field NMR spectrometers equipped with cryogenically cooled probes (1H or 13C optimized) for enhanced sensitivity.
Proper citation: University Health Network Nuclear Magnetic Resonance Core Facility (RRID:SCR_027548) Copy
Core supports biomarker discovery and enhancing future cancer research in the areas of genomics, proteomics and epidemiology. Provides serialized collections of biospeciments throughout patient prognosis. Clinical time point collections are based on input from our expert surgical, medical, and radiation oncologist teams.
Proper citation: University Health Network McCain GU Biobank (RRID:SCR_027521) Copy
Core services include Imaging Modalities:MRI,PET-MRI,CT,PET-CT,Ultrasound / X-Ray,Interventional / Biopsies;Consultation:Pre-grant submission consultations,Pre-trial launch consultations / site initiation visists,Feasibility assessments MRI physics consultation; Protocol Development / Site Feasibility:Industry site feasibility questionnaires, Protocol development of medical imaging studies and clinical trials; Post-Processing of Images:Tumour measurements, Volumetric measurements.
Proper citation: University Health Network Joint Department of Medical Imaging Research Office JDMI RO Core Facility (RRID:SCR_027520) Copy
https://pmlivingbiobank.uhnresearch.ca/
Core provides services for the use of Xenograft (PDX) models listed in open global catalogue of PDX models for comprehensive search and attribute filtering support for clinico-pathological and molecular data. Molecular data and visualization of profiled models could be accessed through the institute's portal.
Proper citation: University Health Network Princess Margaret Living PDX Core Facility (RRID:SCR_027523) Copy
https://www.pmgenomics.ca/pmgenomics/
Core is dedicated to providing access to cost-effective and high quality genomics services including standard and custom-tailored DNA sequencing using Illumina technologies, epigenomics, panel-based profiling (Luminex and Nanostring) and functional genomics. Single cell genomics applications on variety of popular platforms.
Proper citation: University Health Network Princess Margaret Genomics Centre PMGC Core Facility (RRID:SCR_027524) Copy
https://www.clf.stfc.ac.uk/Pages/Octopus-new.aspx
National imaging facility that offers access to single molecule imaging, confocal microscopy, superresolution imaging, light sheet microscopy, optical trapping and cryoscanning electron microscopy. Offers expert guidance and advice for light and electron microscopy experiments alongside advanced instruments for fluorescence and electron microscopy.
Proper citation: Science and Technology Facilities Council Central Laser Facility OCTOPUS Microscopy Core Facility (RRID:SCR_027515) Copy
https://uhnbiospecimenservices.com/
Core provide services for the enhancement and progression of novel and innovative research and discovery. Provides human biospecimen samples such as: fresh frozen and formalin fixed paraffin embedded (FFPE) tissue, compartmentalized blood components such as serum, plasma, and whole blood peripheral blood mononuclear cells (PBMCs) and other biofluids, including saliva and urine; Tissue microarray (TMA) construction and quantitative image analysis of TMA sections, Laser capture microdissection (LCM), digital slide scanning, quantitative image, and pathological/clinical analysis for various tumour sites and DNA/RNA extraction; support and guidance to researchers and biobanks on accessing, collecting, and using human biospecimens and associated data for health research.
Proper citation: University Health Network Biospecimen Services Core Facility (RRID:SCR_027519) Copy
https://pmlivingbiobank.uhnresearch.ca/
Core provides services for the use of patient-Derived tumor Organoid (PDO) model.Organoid models are derived from patient-derived xenograft tissues, primary tumors, and metastatic patient tissues. PMLB organoid repository includes models generated from colorectal, pancreatic, and lung cancer tissues.
Proper citation: University Health Network Princess Margaret Living Biobank PDO Core Facility (RRID:SCR_027530) Copy
Core provides services including Basic High-Throughput Sequencing Analysis, Advanced Data Analysis, High Performance Computing.
Proper citation: University Health Network Bioinformatics and High Performance Computing HPC Core Facility (RRID:SCR_027532) Copy
Offers services to support studies in medical fields across oncology, cardiology, metabolic diseases, radiotheranostics and more.Helps with study design to final data analysis, including GLP-compliant histopathology services.
Proper citation: University Health Network Spatio-Temporal Targeting and Amplification of Radiation Response Core Facility (RRID:SCR_027531) Copy
Core offers services in optical microscopy experiments including: confocal, multiphoton, super-resolution, FRAP, FRET, live-cell timelapse, whole-slide scanning, image analysis and more.
Proper citation: University Health Network Advanced Optical Microscopy Core Facility (RRID:SCR_027535) Copy
https://kdtflow.uhnresearch.ca/
Core offers cell sorting and flow cytometry services. Provided instruments include BD FACS Canto II, Beckman Cytoflex LX, BD FACS ARIA III, AutoMacs Cell Separator.
Proper citation: University Health Network Krembil Discovery Tower Flow Cytometry Core Facility (RRID:SCR_027529) Copy
https://chem.vt.edu/analyticalservices/crystallography.html
Core specializes in single-crystal structure determination of small molecules, inorganic materials, and minerals. The facility houses a Rigaku-Oxford Diffraction Synergy Single-Crystal X-ray Diffractometer equipped with both Cu and Mo sources, variable temperature capabilities (90 – 500 K) and the setup to perform high-pressure diamond-anvil studies.
Proper citation: Virginia Tech Crystallography Lab Core Facility (RRID:SCR_027620) Copy
Core provides data-related support to cancer researchers by offering services like study design consultation, data management, programming, and access to patient data. Its purpose is to help researchers develop and execute studies, manage data, analyze results, and ultimately accelerate cancer research by making large, complex datasets more accessible and usable. CDS team uses evidence-based standards and effective quality assurance procedures from project design to study end. All CDS study staff are HIPAA-compliant and certified in Human Subjects and Good Clinic Practice training.
Proper citation: Fred Hutchinson Cancer Center Collaborative Data Services Core Facility (RRID:SCR_027586) Copy
https://chem.vt.edu/analyticalservices/chromatograhy.html
Facility enables complete qualitative and quantitative analysis of components within complex sample matrices. Provides services for separating mixtures, and supports critical research across numerous fields, including:Chemistry and Biochemistry, Biology and Medicine, Environmental Science and Toxicology, Food, Nutrition, and Pharmaceutical Development. Provides extraction, separation, detection, and quantification of organic and other complex mixtures from gas, solid, or liquid matrices.
Proper citation: Virginia Tech Department of Chemistry Chromatography Core Facility (RRID:SCR_027622) Copy
https://www.sharedfacilities.pitt.edu/wpqic
Core is equipped with suite of cryostats and measurement systems for probing electrical, magnetic, and quantum properties at cryogenic temperatures. Sample preparation capabilities include tools for wafer processing, nanomaterial transfer, and inert atmosphere handling. Deposition systems support thin film growth and surface treatment using a variety of techniques. Wirebonding and related sample preparation tools enable precise device packaging and integration, supporting a broad range of experimental workflows in quantum and nanoscale science.
Proper citation: University of Pittsburgh Western Pennsylvania Quantum Information Core Facility (RRID:SCR_027582) Copy
https://www.bwhneurosciences.org/neurotechnology-studio/
Offers advanced instrumentation and expert support to advance understanding of brain function and brain disease by providing researchers with access to cutting-edge technologies. Provides access to advanced instrumentation for optical microscopy, genomics, metabolic imaging and other technologies, as well as image analysis software. Provides expert support and training, data quality and interpretation.
Proper citation: Brigham and Women’s Hospital NeuroTechnology Studio Core Facility (RRID:SCR_027687) Copy
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