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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Freestanding, nonprofit coordinating center for multi-center clinical trials and epidemiologic research that focus on projects involving eye disorders or type 1 diabetes.
Proper citation: Jaeb Center for Health Research (RRID:SCR_001513) Copy
Web software which helps users create a website or blog. WordPress software can be downloaded and installed with an appropriate web host and minimum requirements. There is also a service called WordPress.com which allows users to get started with a new and free WordPress-based blog in seconds, though it varies in several ways and is less flexible than the self-installed WordPress. An array of plugins and themes are available to further customize a site.
Proper citation: WordPress (RRID:SCR_001518) Copy
International, randomized, double-blinded trial to determine whether weaning to a casein hydrolysate formula during the first 6-8 months of life in place of cow milk based formula reduces the incidence of autoimmunity and type 1 diabetes in genetically susceptible newborn infants. 2160 eligible infants were randomized to test or control formulas when mothers decide to wean from exclusive breastfeeding. The participants will be monitored up to the age of 10 years for the appearance of diabetes-predictive autoantibodies and clinical type 1 diabetes. The TRIGR trial will determine whether delayed exposure to intact food proteins will reduce the chances of developing type 1 diabetes later in life. All babies in the study received the recommendation to breastfeed for at least the first six months of life. If a mother was unable to exclusively breastfeed before the baby was 8 months of age, her child was randomly assigned to one of two groups. One group of these babies received a trial formula based on extensively hydrolyzed protein; the other group received another trial formula containing a smaller amount of hydrolyzed protein. In the hydrolyzed formula, the big protein molecules have been split into very small fragments to provide a source of nutritional amino acids, but the fragments are likely too small to stimulate the immune system. The TRIGR trial will also be able to analyze whether exclusive breastfeeding per se can reduce the risk of the children to develop type 1 diabetes.
Proper citation: TRIGR (RRID:SCR_001550) Copy
Medical university in Stockholm, Sweden that offers more than fifty disciplines of medicine for study.
Proper citation: Karolinska Institute; Stockholm; Sweden (RRID:SCR_001548) Copy
Public doctoral university located in Manhattan, Kansas that is involved with research, especially agricultural.
Proper citation: Kansas State University; Kansas; USA (RRID:SCR_001533) Copy
https://github.com/CollasLab/edd
A ChIP-seq peak caller for detection of megabase domains of enrichment.
Proper citation: Enriched Domain Detector (RRID:SCR_001693) Copy
Geospatial software for monitoring and modeling the Earth system. Includes tools for GIS, image processing, surface analysis, vertical applications for land change analysis and earth trends exploration, and more.
Proper citation: IDRISI (RRID:SCR_001696) Copy
http://www.bioconductor.org/packages/devel/bioc/html/CNVrd2.html
A software package that uses next-generation sequencing data to measure human gene copy number for multiple samples, indentify SNPs tagging copy number variants and detect copy number polymorphic genomic regions.
Proper citation: CNVrd2 (RRID:SCR_001723) Copy
http://bioconductor.org/packages/2.13/bioc/html/sSeq.html
Software package to discover the genes that are differentially expressed between two conditions in RNA-seq experiments. Gene expression is measured in counts of transcripts and modeled with the Negative Binomial (NB) distribution using a shrinkage approach for dispersion estimation. The method of moment (MM) estimates for dispersion are shrunk towards an estimated target, which minimizes the average squared difference between the shrinkage estimates and the initial estimates. The exact per-gene probability under the NB model is calculated, and used to test the hypothesis that the expected expression of a gene in two conditions identically follow a NB distribution.
Proper citation: sSeq (RRID:SCR_001719) Copy
http://www.kcl.ac.uk/index.aspx
Public research university located in London, United Kingdom that offers undergraduate, graduate, and professional degree programs in medicine, economics, social sciences, etc.
Proper citation: King's College London; London; United Kingdom (RRID:SCR_001744) Copy
http://bioinformatics.dreamhosters.com/?page_id=113#Genomic_Protein_Sequence_Analysis
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 10th,2023. An R software package for detecting and correcting biases in RNA-Sequencing data.
Proper citation: RNASeqBias (RRID:SCR_001739) Copy
http://bioinformatics.med.yale.edu/group/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 10th,2023. An R code for Bayesian modeling of paired RNA-seq experiments.
Proper citation: pairedBayes (RRID:SCR_001738) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on March 28, 2017. Foundation that helps junior physicians and neuroscientists continue their research on Parkinson's Disease and related disorders, with financial support for professional and intellectual development. It promotes an international community of researchers, focusing on the young enthusiastic investigators and clinicians who might otherwise be forced to abandon their ideas and efforts.
Proper citation: Melvin Yahr International Parkinson's Disease Foundation (RRID:SCR_001652) Copy
http://sourceforge.net/projects/dnaclust/
Software program for clustering large number of short similar DNA sequences. It was originally designed for clustering targeted 16S rRNA pyrosequencing reads.
Proper citation: DNACLUST (RRID:SCR_001771) Copy
http://intermine.github.io/intermine.org/
An open source data warehouse system built for the integration and analysis of complex biological data that enables the creation of biological databases accessed by sophisticated web query tools. Parsers are provided for integrating data from many common biological data sources and formats, and there is a framework for adding data. InterMine includes a user-friendly web interface that works "out of the box" and can be easily customized for specific needs, as well as a powerful, scriptable web-service API to allow programmatic access to data.
Proper citation: InterMine (RRID:SCR_001772) Copy
Global nonprofit biological resource center (BRC) and research organization that provides biological products, technical services and educational programs to private industry, government and academic organizations. Its mission is to acquire, authenticate, preserve, develop and distribute biological materials, information, technology, intellectual property and standards for the advancement and application of scientific knowledge. The primary purpose of ATCC is to use its resources and experience as a BRC to become the world leader in standard biological reference materials management, intellectual property resource management and translational research as applied to biomaterial development, standardization and certification. ATCC characterizes cell lines, bacteria, viruses, fungi and protozoa, as well as develops and evaluates assays and techniques for validating research resources and preserving and distributing biological materials to the public and private sector research communities.
Proper citation: ATCC (RRID:SCR_001672) Copy
http://www.bioconductor.org/packages/release/bioc/html/unifiedWMWqPCR.html
Software package that implements the unified Wilcoxon-Mann-Whitney Test for qPCR data. This modified test allows for testing differential expression in qPCR data.
Proper citation: unifiedWMWqPCR (RRID:SCR_001706) Copy
https://github.com/sbotond/rlsim
Software package for simulating RNA-seq library preparation with parameter estimation.
Proper citation: rlsim (RRID:SCR_001703) Copy
http://www.bioconductor.org/packages/release/bioc/html/RSVSim.html
A software package for the simulation of deletions, insertions, inversions, tandem duplications and translocations of various sizes in any genome available as FASTA-file or data package in R. SV breakpoints can be placed uniformly accross the whole genome, with a bias towards repeat regions and regions of high homology (for hg19) or at user-supplied coordinates.
Proper citation: RSVSim (RRID:SCR_001777) Copy
Annual Reviews offers comprehensive, timely collections of critical reviews written by leading scientists. It publishes authoritative, analytic reviews in 37 focused disciplines within the Biomedical, Life, Physical, and Social Sciences. The mission of Annual Reviews is to provide systematic, periodic examinations of scholarly advances in a number of fields of science through critical authoritative reviews. The comprehensive critical review not only summarizes a topic but also roots out errors of fact or concept and provokes discussion that will lead to new research activity. The critical review is an essential part of the scientific method. Sponsors: Annual Reviews is a non-profit organization created and managed by scientists to serve science by publishing reviews in 40 different scientific fields.
Proper citation: Annual Reviews: A Nonprofit Scientific Publisher (RRID:SCR_001655) Copy
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