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http://www.rockefeller.edu/ddrc/

Core guides researchers in drug discovery by improving efficiency of their bioassays, identifying compounds and targets of function, and in utilizing technologies for measurement of drug/receptor interactions.Center also has spectroscopic and calorimetric equipment for use in studies of interactions of drugs with their targets.

Proper citation: Rockefeller University Fisher Drug Discovery Core Facility (RRID:SCR_020985) Copy   

•   Source: SciCrunch Registry

http://www.rockefeller.edu/genomics/

Core offers services and instruments to support genomics research. Houses Illumina NovaSeq, NextSeq, MiSeq sequencers, 10X Genomics Chromium Single Cell System, and Life Technologies QuantStudio 12K flex realtime PCR system. Provides several accessory instruments for sample quantity and quality validation: Agilent Bioanalyzer, Agilent TapeStation, NanoDrop spectrophotometer, and Qubit spectrophotometer.Offers full services for genomic DNA-Seq and RNA-Seq, specializing in preparation of libraries from very small amount of starting total RNA. Users can also prepare their own libraries and use the center�s sequencing-only services. Offers free consultations on experimental designs, library preparation options, sequencer choice, sequencing depth and coverage, and biological replicates.Performs initial sequencing data analysis for all users, and can assist with downstream analysis.

Proper citation: Rockefeller University Genomics Resource Center Core Facility (RRID:SCR_020986) Copy   

•   Source: SciCrunch Registry

https://pennstatehealthnews.org/topics/cryo-em/

Cryo-electron microscopy (cryo-EM) facility providesTitan Krios cryo-transmission electron microscope that is fully equipped for high-throughput data collection of the utmost quality possible. It has the ability to determine the atomic structure of a single protein or view molecules interacting in their cellular context. Provides guidance, training or data collection for researchers at the College of Medicine.Equipment includes Zeiss LSM 980 Cryo-Confocal Microscope,300 kV Krios Cryo-TEM for SPA and tomography, Equipped with Volta phase plates, bioquantum energy filter and K3 direct electron detector,200 kV thermionic JEOL 2100 for cryo-imaging, cryo-tomography, and standard imaging of stained grids.

Proper citation: Penn State Hershey College of Medicine cryo-EM Core Facility (RRID:SCR_021178) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/compchem/index.html

Core offers wide variety of services, including access to the Schrodinger platform and high-throughput computing. Services include examining molecular structures and mechanisms in atomic detail and provide graphically rich analysis suitable for inclusion in publications and grants.

Proper citation: University of Nebraska Medical Center Computational Chemistry Core Facility (RRID:SCR_021023) Copy   

•   Source: SciCrunch Registry

https://www.umass.edu/ials/light-microscopy

Core provides resources for imaging model organisms, tissue, cells, biomaterials, and artificial structures and houses equipment including almost every light microscopy imaging modality presently available. Cell culture facilities are also available nearby as well as other routine items necessary for biological imaging and material imaging. This facility has been designated Nikon Centers of Excellence, thus providing unique opportunity for training, demonstration, instrument development, and research.We excel in use of telemicroscopy through use of remote imaging sessions, remote control of all instruments, and remote data analysis sessions available to all users.Provides training to all users that plan to conduct experimentation. Following an initial consultation in which experimental requirements, expected outcomes, and careful scrutiny of feasibility, training and/or access is arranged through the Director.

Proper citation: University of Massachusetts Light Microscopy Core Facility (RRID:SCR_021148) Copy   

•   Source: SciCrunch Registry

https://www.rockefeller.edu/cemrc/

Offers new cryo-electron microscopy tools available to University researchers, allowing for visualization of three-dimensional structures of molecules and macromolecular complexes in solution.

Proper citation: Rockefeller University Cryo Electron Microscopy Resource Center Core Facility (RRID:SCR_021146) Copy   

•   Source: SciCrunch Registry

https://www.bmh.manchester.ac.uk/research/facilities/electron-microscopy/

Offers expertise and equipment tailored for biological samples mostly. Houses four electron microscopes.Preparation laboratory includes range of specialised room temperature and cryo sample preparation equipment, ultramicrotomes and suite of computer workstations for image processing.Electron microscopy staff are available to train and assist.

Proper citation: University of Manchester Electron Microscopy Core Facility (RRID:SCR_021147) Copy   

•   Source: SciCrunch Registry

https://htrc.uchicago.edu

Coordinated, centralized, and dedicated program for procuring, processing, dispersing and assessing all types of biospecimens together with downstream histology services. CAP Accredited.

Proper citation: University of Chicago Human Tissue Resource Center Core Facility (RRID:SCR_019199) Copy   

•   Source: SciCrunch Registry

https://www.ualberta.ca/medicine/research/corefacilities/flow-cytometry-facility/index.html

Flow Cytometry Facility offers analytical flow cytometry, cell sorting and data analysis.Instruments include FACSArias, FACSCanto II, LSR-Fortessas, Attune NxT, and Amnis ImageStream mkII.

Proper citation: University of Alberta Faculty of Medicine and Dentistry Flow Cytometry Core Facility (RRID:SCR_019195) Copy   

•   Source: SciCrunch Registry

https://voices.uchicago.edu/confocal/

Offers microscopy imaging, including bright field color and DIC, fluorescence multi-dimension,TIRFM including bleaching, ablation, FLIM and high resolution, highspeed, high sensitivity, confocal, and physiologic techniques, STED, GSD3D, lightsheet selective plane illumination and lattice lightsheet structured illumination super resolution microscopy.

Proper citation: University of Chicago Integrated Light Microscopy Core Facility (RRID:SCR_019197) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/cryo-electron-microscopy-laboratory/

Shared resource hosting advanced cryo–electron microscopes fitted with direct detectors as well as equipment for sample preparation.

Proper citation: New York University School of Medicine Langone Health Cryo-Electron Microscopy Laboratory Core Facility (RRID:SCR_019202) Copy   

•   Source: SciCrunch Registry

https://www.chemistry.ucsc.edu/research/facilities/index.html

Shared research facility dedicated to improving human health by finding next generation of therapeutic agents against wide variety of diseases. The CSC is driving innovation in drug discovery by bringing together experts in drug screening with cell and molecular biologists engaged in disease research. Has assembled diverse collection of compounds derived from marine organisms, setting our facility apart as a leader in the discovery of therapeutic natural products.

Proper citation: University of California, Santa Cruz Chemical Screening Center Core Facility (RRID:SCR_021114) Copy   

•   Source: SciCrunch Registry

https://lmf.mdibl.org/

Core provides professional scientific expertise in light microscopy. Offers access to hardware and software as well as expert guidance at any step of imaging project, from experimental design to image analysis.Comprises eight microscope systems including two laser scanning confocal microscopes including one Olympus inverted confocal microscope system (FV1000) and one Zeiss inverted confocal microscope system (LSM-980) equipped with Airy scan 2 for super resolution and 2-photon technology for in-vivo deep imaging with temperature controlled chamber. One spinning disk confocal including Nikon inverted spinning disk microscope system with incubation chamber (Eclipse Ti with Yokogawa disk CSU-W1), two Zeiss widefield microscopes for brightfield and epifluorescence illumination (Zeiss Apotome and Zeiss Colibri), three macroscopes systems to observe large samples or complete model organisms in brightfield and epifluorescence including one Olympus stereomicroscope system (MVX10) and two Zeiss stereomicroscope systems (SteREO Discovery V12), fully automated and one AxioZoom V16 , fully automated with ApoTome attachment.

Proper citation: Mount Desert Island Biological Laboratory Light Microscopy Core Facility (RRID:SCR_019166) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/flow-cytometry/

Offers Flow Cytometry analysis, Cell sorting, Flow Imaging analysis.Available cytometers include 4-color BD FACSCalibur,10-color BD FACSCanto 10-color Amnis ImageStream X Mk II imaging cytometer,Special-order 16-color BD LSR II,16-color BD LSR Fortessa,17-color BD FACS Aria SORP high-performance cell sorter,23-color BD FACSSymphony.

Proper citation: Penn State Hershey College of Medicine Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_021134) Copy   

•   Source: SciCrunch Registry

https://www.ualberta.ca/medicine/research/corefacilities/lipidomics-core/index.html

Core assists researchers in isolating and quantifying lipids and lipid related molecules in experimental samples.Core uses high performance liquid chromatography, gas chromatography, and fast protein liquid chromatography for both qualitative and quantitative analysis of lipids and lipoproteins, as well as other compounds by special request.Not-for-profit, pay-per-use facility, with graduated fee schedule based on client affiliation.

Proper citation: University of Alberta Faculty of Medicine and Dentistry Lipidomics Core Facility (RRID:SCR_019176) Copy   

•   Source: SciCrunch Registry

https://www.uclalipidomics.net/

Offers automated sample preparation and two distinct mass spectrometry platforms with services, ranging from shotgun lipidomics to isotope labeling and mathematical modeling of lipid flux parameters.Offers data analysis and consultation services to provide users with accurate analysis of lipid metabolic parameters.

Proper citation: University of California at Los Angeles Lipidomics Lab Core Facility (RRID:SCR_019210) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/rc/resources/petalibrary

Provides service to support storage, archival, and sharing of research data. Available at subsidized cost to any researcher affiliated with University of Colorado Boulder.

Proper citation: University of Colorado Boulder High Performance Computing PetaLibrary Core Facility (RRID:SCR_019299) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/cytometry-cell-sorting-laboratory

Provides access to flow cytometry and cell sorting technologies and instruments. If your research requires cytometric analysis, instruments acquire optical measurements using different lasers to detect fluorophores with high level of precision.

Proper citation: New York University Grossman School of Medicine Langone Health Cytometry and Cell Sorting Laboratory Core Facility (RRID:SCR_019179) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/flow-cytometry

Provides cytometry based services including cell sorting, flow cytometry and mass cytometry. Provides training, education, and experimental design assistance.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Flow Cytometry Shared Resource Core Facility (RRID:SCR_022035) Copy   

•   Source: SciCrunch Registry

https://mass-spec.ku.edu/

Provides range of mass spectrometry based services including small molecule analysis and quantitation, peptide and protein MW determination; MS based proteomics services and associated bioinformatics including: global proteome IDs and targeted proteomics, post-translational modification mapping, quantitative proteomics, consultation for designing proteomics experiments, thermal protein profiling and cellular thermal shift assay analysis.

Proper citation: University of Kansas Mass Spectrometry and Analytical Proteomics Core Facility (RRID:SCR_021857) Copy   

•   Source: SciCrunch Registry