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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.itntrialshare.org/
Immune tolerance data management and visualization portal for studies sponsored by Immune Tolerance Network (ITN) and collaborating investigators. Data from published studies are accessible to any user; data from current in-progress studies are accessible to study investigators and collaborators. Includes links to published Figures, tools for visualization and analysis of data, and ability to query study data by subject, group, or any other study parameter.
Proper citation: Immune Tolerance Network TrialShare (RRID:SCR_013699) Copy
http://james.psych.umn.edu/iiV/welcome.html
:iiV is an interactive brain imaging data display tool written in Java. It displays 3-D data set as slices perpendicular to the 3 major axis. Individual slice voxels are mapped thru a linear scaling, threshold and color table to displayable pixel values. Any number of slices from any number of data files may be arranged, annotated, overlaid, cropped, zoomed and rotated. iiV maintains the original data internally for mouse selection and display of original voxel values. If input locations map to a real world valued coordinates that mapping may be applied to display selected voxel locations in real coordinates. Slices may also include tracking crosshairs and automatically update to display the same region of the brain as selected in another slice. iiV includes a fairly complete set of editing commands including selection, drag, group, delete, and undo/redo commands. It also includes a script language for saving and reloading of the interactive display and creating animated demos. iiV supports reading ANALYZE, ECAT, ECAT7, DICOM, GIF, JPEG, PPM, Stimulate SDT, and raw data formats and saving what is displayed as scripts, GIF and PPM files. :
Proper citation: iiV (internet image Viewer) (RRID:SCR_013615) Copy
http://neuroinformatics.mitre.org/projects.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 15, 2013. A Java-based tool for managing and sharing MRI/DTI datasets, and related subject and protocol metadata. Data entry, data access, general query, reporting, analysis, and administrative operations occur through browser-based forms. NeuroServ works with a webserver (Tomcat) and a backend database (e.g., Postgres); a schema and over 40 forms are provided in the distribution. Support for DTI includes entry of multi-orientation raw DWI files, semi-automated normalization to the B0 image and quality filtering. Planned extensions include full DTI processing through image production and data sharing using the SSC incremental visiblity model.
Proper citation: NeuroServ (RRID:SCR_013617) Copy
http://www.bic.mni.mcgill.ca/software/mni_autoreg/
Web site last updated August 26, 1998 Automatic method for comparing different MRI datasets by visual inspection of equivalent anatomical planes. Implementation is based on multi-scale, three dimensional (3D) cross-correlation, to register a given volumetric data set to an average MRI brain (n > 300) aligned with the Talairach stereotaxic coordinate system. :
Proper citation: The MNI AutoReg Software Package (RRID:SCR_013621) Copy
http://icb.med.cornell.edu/crt/SigPath/DetailedInformation.xml
SigPath is a prototype of an information system for cell signaling pathways and networks. A primary emphasis of SigPath is that biochemical information can be stored both at the qualitative and quantitative levels. When information is stored quantitatively, SigPath can assist users in generating quantitative models that can be used to simulate how the concentrations of the molecules involved in a model change over time. For background, design goals, tutorials, and contact information, visit the SigPath Project Pages :Gs pathway, LSD_binds_serotonin 2AR, MAPK cascade, EGFR signaling and MAP kinase cascade, EGF receptors, mGluR activation :
Proper citation: Sigpath (RRID:SCR_013620) Copy
http://hbatlas.org/pages/publications
A research paper with supplementary materials reporting the generation and analysis of exon-level transcriptome and associated genotyping data. The experiment represented both males and females of multiple ethnicities and examines gene regulation and expression in different areas of the brain. A data set on the human brain transcriptome as well as insights into the transcriptional foundations of human neurodevelopment is provided.
Proper citation: Spatio-temporal transcriptome of the human brain (RRID:SCR_013743) Copy
Welcome to the Syracuse Biomaterials Institute! We are a new, interdisciplinary institute focused on research in biomaterials, smart medical devices, and biological/tissue-engineered constructs. Biomaterials are natural and synthetic substances designed to treat, augment, or replace tissues and organs of the human body as treatments to disease or injury. An outgrowth of the long-standing Biomaterials Group in the Biomedical and Chemical Engineering Department, the Syracuse Biomaterials Institute (SBI) was launched in Fall, 2007, through strategic investments by Syracuse University, New York State Foundation for Science, Technology and Innovation (NYSTAR), and private donations. SBI is a cohesive collection of highly collaborative faculty spanning eight (8) academic units, including faculty from SUNY Upstate Medical University and SUNY College of Environmental Science and Forestry. Our researchers are engaged in a wide spectrum of problems, ranging from fundamental studies of the biochemical and physical processes controlling cell functions to the development of new technologies for biomedical applications. In addition to our collaborative research and teaching activities, we are excited to be designing our future SBI home, planned for Fall 2009, that will collocate our research groups and central laboratory facilities. :jobs board, postdoctoral training program, graduate training program, portal :
Proper citation: Syracuse Biomaterials Institute (RRID:SCR_013626) Copy
i2b2 (Informatics for Integrating Biology and the Bedside) is an NIH-funded National Center for Biomedical Computing based at Partners HealthCare System. The i2b2 Center is developing a scalable informatics framework that will enable clinical researchers to use existing clinical data for discovery research and, when combined with IRB-approved genomic data, facilitate the design of targeted therapies for individual patients with diseases having genetic origin. For some resources (e.g. software) the use of the resource requires accepting a specific (e.g. OpenSource) license.
Proper citation: Informatics for Integrating Biology and the Bedside (RRID:SCR_013629) Copy
An Antibody supplier
Proper citation: Abnova Corporation (RRID:SCR_013592) Copy
A web application which allows users to collect data, perform complex analyses, and generate results. Users can upload data sets from their computer or from the internet for data analysis and graph creation which can be saved, printed, and downloaded. More than 15,000 statistical data sets are available.
Proper citation: StatCrunch (RRID:SCR_013992) Copy
The Theoretical and Computational Biophysics Group (TCBG), an NIH Resource for Macromolecular Modeling and Bioinformatics, was founded by Professor Klaus Schulten in 1989 and is located at the Beckman Institute of the University of Illinois at Urbana-Champaign (UIUC). The group is led by Professor Klaus Schulten (Physics, Biophysics, Chemistry) with Professors Laxmikant Kale (Computer Science), Zaida Luthey-Schulten (Chemistry) and Alek Aksimentiev (Physics), and with the Resource''s assistant director Dr. Emad Tajkhorshid (Biophysics). Research and development activities of the TCBG center on the structure and function of supramolecular systems in the living cell, and on the development of new algorithms and efficient computing tools for structural biology. :The TCBG brings the most advanced molecular modeling, bioinformatics, and computational technologies to bear on questions of biomedical relevance. We extend, refine and deliver these technologies in response to experimental progress and emerging needs of the wide biomedical research community. We magnify the impact of our work through direct collaboration with experimental researchers, the distribution of cutting-edge and user-friendly software, and via extensive training, service, and dissemination efforts. :cell, algorithm, simulation software, membrane potential, genome, molecule, ion channel, chromatin, Image Processing software, data Data visualization software, simulation software; Membrane Biophysics, Mechanobiology, Nanoengineering, Bioenergetics, Neurobiology, Molecular Dynamics, cellular membrane, osmotic pressure, proteins (use protein), Gatekeeper Protein, membrane, mechanosensitive channel of small conductance (MscS), Visual Molecular Dynamics (VMD), Quantum Biology, quantum chemistry, Molecular Dynamics Simulator, Nanoscale Imaging, cellular membrane tension, bacterial cell, electron paramagnetic measurements, computer modeling, atomic detail, computational microscope, Lipoproteins [high density lipoproteins (HDL)], Petascale Computing, Macromolecular Modeling, Bioinformatics, supramolecular systems, living cell, algorithms (use algorithm), computing tools, structural biology, molecular modeling, computational technologies, membrane proteins, structural information, molecular visualization, Molecular modeling tools, structural information, bioinformatics databases, molecular dynamics simulations, interactive modeling, collaborations, theoretical, experimental researchers, light energy, electrical membrane potentials (use membrane potential, add term as syn), synthesis of ATP, photosynthetic systems, storage and control of genetic information, classical and quantum dynamical motion of biopolymers, numerical experiments, non-equilibrium statistical mechanics, elasticity theory, theory of disordered systems, collaborative environment, Software Development, cells (use cell), molecular graphics viewer, static and dynamic structures, DNA sequencing, genomes (use genome), direct manipulation and observation, single molecules (use molecule), bioenergetic proteins, nanotechnology, steered/interactive molecular dynamics, dissemination, coarse-graining methods, residue-based and shape-based coarse graining, CG, polymeric systems, Computational Environment, Training, Workshops, Tutorials, Case Studies, Classes, research, Highly Cited, compute power, visualization equipment, desktop workstations, lipid bilayers, allow passage of ions across the membrane (use ion channel), mechanotransduction, membrane tension, 3-D graphics, built-in scripting, animating, analyzing, ideal DNA interbasepair helical parameters, plugin, nucleosomes, antialiasing, depthcueing, Molecular Representations, analysis and Data visualization software (use Image Processing software, and data Data visualization software, add terms as syn.), computer simulations (use simulation software), photosynthetic systems, computational clusters :
Proper citation: Theoretical and Computational Biophysics Group (TCBG) (RRID:SCR_013598) Copy
http://www.nitrc.org/projects/iterdrwsp/
Software which aims to better estimate the neuronal activation of an individual using the results of an independent component analysis (ICA) method applied to a temporally concatenated group of functional magnetic resonance imaging (fMRI) data (i.e., Tc-GICA method). This approach employs iterative LS solutions to refine both the individual SPs and TCs with an additional a priori assumption of sparseness in the SPs (i.e., minimally overlapping SPs) based on L(1)-norm minimization.
Proper citation: Iterative dual-regression with sparse prior (RRID:SCR_014128) Copy
http://actimetrics.com/products/limelight/
A video tracking system designed for high-throughput behavioral experiments. LimeLight can track up to 4 arenas at once and can collect images at up to 30 frames per second for one animal or up to 8 frames per second when tracking 4 arenas at once. The tracking system has 2 different hardware configurations: the 1-camera system can be used to record 1 to 4 animals at once, while for multiple animals, each one is placed in a separate arena in one quadrant of the image. The software contains productivity features such as flexible arena setup, user-defined behavior scoring, stimulus control, and various analytical functions for quantifying behavior. The program is designed for experiments such as Open Field, Plus Maze, Radial Arm Maze, Zero Maze, Novel Object Recognition, Conditioned Place Preference, and Barnes Maze.
Proper citation: Limelight (RRID:SCR_014254) Copy
http://www.nitrc.org/projects/lwdp/
A lightweight framework for setting up dependency-driven processing pipelines. The tool is essentially a configurable shell script (sh/bash), which can be included in other scripts and primarily provides a small number of utility functions for dependency checking and NFS-safe file locking for cluster processing.
Proper citation: Lightweight Data Pipeline (RRID:SCR_014135) Copy
A database where researchers can read and post reviews of publishing experiences with scientific journals. When writing comments, reviewers are adivsed to provide facts where possible, be specific, be honest, check the review, and offer constructive criticism when writing a negative report. Journalysis collates submitted reviews and data for each journal and provides useful summary information (metrics). Authors wanting to find out more about specific journals can search its databases and find the best journal for their next manuscript submission. Journals can use these reviews and metrics to demonstrate high publishing standards, or to improve standards where reviews may be negative.
Proper citation: Journalysis (RRID:SCR_014015) Copy
http://www.nitrc.org/projects/cmind_py_2014/
A python toolbox for analysis of MRI images. It relies on calls to a number of widely tested algorithms from the FMRIB software library (FSL) and the advanced normalization tools (ANTS) to provide analysis of simultaneously acquired ASL/BOLD fMRI data. It was developed for analyzing the datasets collected as part of the Cincinnati MR Imaging of NeuroDevelopment (C-MIND) project.
Proper citation: CMIND PY (RRID:SCR_014097) Copy
A collection of concise summaries of scientific articles that link back to the physical article. Users can contribute resources to the site and may choose to provide a summary; if they do not, Useful Science will do so. Summaries are then tagged with the appropriate topic. Topics that relate to everday life such as health, fitness, nutrition, and sleep are the main focus of the site.
Proper citation: Useful Science (RRID:SCR_013968) Copy
https://www.plos.org/article-level-metrics
A portal which provides access to article level metrics, PLOS news, and videos and presentations. PLOS ALMs provides altmetrics for every article published in PLOS. Researchers can stay up-to-date with their published work and share information about the impact of their publications with collaborators, funders, institutions, and the research community at large.
Proper citation: PLOS Article-Level Metrics (RRID:SCR_014022) Copy
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