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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.nitrc.org/projects/aperture/
A MATLAB-based toolbox for analysis of EEG, MEG, and ECoG data. APERTURE allows flexible multivariate analysis of ERPs and oscillatory activity and supports mass-univariate analysis with advanced statistical tests. Computations are accelerated using parallel computing supported through the MATLAB distributed computing toolbox. Examination of large, high-dimensional datasets is made simple through data visualization tools, including advanced plotting routines and generation of PDF reports with many figures.
Proper citation: APERTURE (RRID:SCR_014082) Copy
A software package for microplate reader control and microplate data analysis. It includes analysis templates for a variety of assays run on Molecular Devices microplate readers.
Proper citation: SoftMax Pro Data Acquisition and Analysis Software (RRID:SCR_014240) Copy
http://www.photonics.com/Product.aspx?PRID=47380
Image processing software used to modify and clarify sample images for FluoView FV1000 range of confocal laser scanning microscopes and Fluoview FV1000MPE multiphoton excitation systems. The software incorporates high-dynamic-range imaging, minimized signal-to-noise ratios, partial stitching with multiarea time-lapse imaging, and channel unmixing. The software also allows users to select specific areas of the whole sample, which can stitched together.
Proper citation: FluoView FV10-ASW software (RRID:SCR_014215) Copy
https://www.phenix-online.org/documentation/reference/phaser.html
Crystallographic software which solves structures using algorithms and automated rapid search calculations to perform molecular replacement and experimental phasing methods.
Proper citation: Phaser (RRID:SCR_014219) Copy
http://www.mrc-lmb.cam.ac.uk/harry/imosflm/ver721/introduction.html
Software which processes diffraction data/images and produces an MTZ file of reflection indices with their intensities, standard deviations, and other parameters. The MTZ file is passed onto other programs of the CCP4 program suite for further data reduction. iMosflm processes data from CCD and pixel detectors. It is available for Windows, Mac OSX and Linux platforms. Tutorials are available at the website.
Proper citation: iMosflm (RRID:SCR_014217) Copy
http://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/
Software for macromolecular model building, model completion and validation, and protein modelling using X-ray data. Coot displays maps and models and allows model manipulations such as idealization, rigid-body fitting, ligand search, Ramachandran plots, non-crystallographic symmetry and more. Source code is available.
Proper citation: Coot (RRID:SCR_014222) Copy
http://shelx.uni-ac.gwdg.de/SHELX/
A set of software programs that utilizes dual spaces algorithms for the determination of small and macromolecular crystal structures by single crystal X-ray and neutron diffraction. Libraries, extra files and environment variables are not required for the executables. SHELX is intended to be run on a command prompt but may be called from GUIs such as shelXle, Olex2, Oscail or WinGX, or hkl2map., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: SHELX (RRID:SCR_014220) Copy
Software designed to provide a multi-level hierachical approach for the most commonly used algorithms in macromolecular structure determination. Features include heavy atom searching, experimental phasing (including MAD and MIR), density modification, crystallographic refinement with maximum likelihood targets, and NMR structure calculation using NOEs, J-coupling, chemical shift, and dipolar coupling data. Modules, libraries, utility programs, tutorials, and a syntax manual are available on the website.
Proper citation: Crystallography and NMR System (CNS) (RRID:SCR_014223) Copy
http://www.nitrc.org/projects/cta_toolbox
A Matlab tool to perform statistical analysis on cortical thickness signals on brain surfaces obtained from Freesurfer. It is used for multi-resolutional analysis of such cortical thickness signals and detecting group differences. It is based on the Spectral Graph Wavelet Transform (SGWT) toolbox and provides plug and play methods for deriving Wavelet Multiscale Descriptor (WMD), cortical thickness smoothing using SGWT, Multivariate General Linear Model (MGLM), and False Discovery Rate (FDR).
Proper citation: Wisconsin Cortical Thickness Analysis (CTA) Toolbox (RRID:SCR_014180) Copy
http://www.nitrc.org/projects/bratumia
Segmentation software for multimodal image analysis of brain tumor studies. It performs volumetric segmentation of healthy and tumor tissues by employing multispectral MRI sequences. Segmented tissues include Gray Matter, White Matter, Cerebrospinal Fluid, necrotic core, edema, non-enhancing tumor and enhancing tumor.
Proper citation: BraTumIA (Brain Tumor Image Analysis) (RRID:SCR_014184) Copy
An online rental equipment marketplace which connects renters to instrument suppliers from various industries. Renters can rent directly from suppliers or request quotes from different suppliers.
Proper citation: KWIPPED (RRID:SCR_014061) Copy
A production service resource which allows researchers to conduct experimental procedures through the cloud. Researchers can ship samples for an experiment to Emerald, then design the experiment(s) over the web using ECL software. Emerald then conducts the experiment(s) in an automated lab as specified, organizing the data into a database in the cloud. Samples are then shipped back to the lab (within a metter of days) and results can be analyze ECL's data analysis suite. Standard experiment types include but are not limited to: analytical balance readings, light microscopy, solid phase extraction, flourescence thermodynamics, RNA extraction/cDNA prep, and Western blot. Additional experiment types may be contributed.
Proper citation: Emerald Cloud Lab (RRID:SCR_013976) Copy
http://www.nitrc.org/projects/openvibe
A multi-platform software dedicated to designing, testing and using brain-computer interfaces (BCI). OpenViBE is a software for real-time neurosciences that can be used to acquire, filter, process, classify and visualize brain signals in real time.
Proper citation: OpenViBE (RRID:SCR_014156) Copy
http://www.nitrc.org/projects/openwalnut/
Open source tool for multi-modal medical and brain data visualization. It is a tool for the scientific user and a powerful framework for the visualization researcher. It is written in Standard C++ and uses a number of portable libraries (e.g. Qt, Boost and OpenSceneGraph). It runs on common GNU/Linux operating systems, Mac OSX and Windows.
Proper citation: OpenWalnut (RRID:SCR_014157) Copy
http://www.nitrc.org/projects/csa-odf
A Matlab toolbox that computes the Q-Ball Imaging Orientation Distribution Function in Constant Solid Angle (CSA-ODF) for diffusion-weighted MRI.
Proper citation: Orientation Distribution Function in Constant Solid Angle (CSA-ODF) (RRID:SCR_014158) Copy
http://www.nitrc.org/projects/niistat/
A set of Matlab scripts for analyzing neuroimaging data from clinical populations. The NiiStat tools are designed to correlate behavioral data (task performance) with brain imaging data.
Proper citation: NiiStat (RRID:SCR_014152) Copy
http://www.cytobank.org/index.html
A cloud-based platform which allows users to analyze, visualize, and archive multiparamter cytometry data for single-cell biology. Multiple single-cell data sets can be analyzed and visualized simultaneously with a variety of graphics, inlcuding Sunburst, SPADE, and viSNE. Users can store and back up related data such as protocols, microscopy images, and presentations and collaborate and share analysis and data sets with other Cytobank users. Cytobank also provides a variety of services and training sessions to assist with experiment workflow.
Proper citation: Cytobank (RRID:SCR_014043) Copy
http://www.nitrc.org/projects/ruby-nifti/
A library for handling NIfTI data in the Ruby programming language. Ruby NIfTI supports basic read and write access to NIfTI files, including basic and extended header information and image information. It doesn't attempt to touch the image data but it does provide access to qform and sform orientation matrices. It also provides a nice interface to get at NIfTI info from within Ruby.
Proper citation: Ruby NIfTI (RRID:SCR_014164) Copy
http://www.nitrc.org/projects/pca-scalar-mesh
An implementation of standard PCA algorithms for use on scalar or vector data sets. Kernel PCA is implemented in this class, where the data sets are scalar or vector valued functions assigned at each of the points in a PointSet. A Gaussian Distance Kernel class is provided with the PCA class.
Proper citation: Principal Components Analysis of Scalar, Vector, and Mesh Vertex Data (RRID:SCR_014163) Copy
http://www.psygenet.org/web/PsyGeNET/menu;jsessionid=y6kqy9lqlxymr0nwwkkfo84
Knowledge platform on psychiatric disorders and their genes. Resource for exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of database and set of analysis tools and is the result of the integration of information from DisGeNET and data extracted from the literature by text mining, followed by curation by domain experts.
Proper citation: PsyGeNET (RRID:SCR_014406) Copy
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