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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.cores.emory.edu/ici/index.html
Provides light microscopy. Offers expertise in imaging for experimental needs.
Proper citation: Emory University Emory Integrated Cellular Imaging Core Facility (RRID:SCR_023534) Copy
https://www.huck.psu.edu/core-facilities/cryo-electron-microscopy-facility
Cryo-Electron Microscopy Facility houses FEI Titan Krios microscope that offers data collection for life sciences while incorporating materials science applications. Used for creating super high definition 3D images of atoms and molecules. Facility allows for fully automated atomic resolution single particle and high contrast tomography tilt-series data collection. Additional microscopy components permit a full range of materials science applications, including EELS, STEM, and DPC. Facility also houses ThermoFisher Arctica G2.
Proper citation: Pennsylvania State University Huck Institutes Cryo-Electron Microscopy Core Facility (RRID:SCR_024456) Copy
https://tnprc.tulane.edu/infectious-disease-aerobiology-core
Core focuses on infectious disease aerobiology. Core facilitates biomedical research efforts that require unique demands of aerosol and aerobiology in their respective performance.
Proper citation: Tulane University TNBRC Infectious Disease Aerobiology Core Facility (RRID:SCR_024608) Copy
https://tnprc.tulane.edu/clinical-pathology-core
Clinical Pathology Core performs clinical diagnostic testing for all research and colony animals. This includes complete blood counts, routine chemistry panels, and microbial culture workups. The lab is equipped with Sysmex XN1000v veterinary hematology analyzer, Beckman AU480 chemistry analyzer, and Matrix assisted laser desorption ionization time of flight MALDI-TOF instrument for microbe identification. CPC is staff with American Society of Clinical Pathologist certified licensed Medical Technologists.
Proper citation: Tulane University TNBRC Clinical Pathology Core Facility (RRID:SCR_024609) Copy
Core Facility offers equipment for wide range of light microscopy applications as well as access to advanced bioimaging software. Specialized staff offers personal training and assistance.
Proper citation: Aarhus University Bioimaging Core Facility (RRID:SCR_023876) Copy
https://www.beatson.gla.ac.uk/advanced-technologies/bair.html
Core to uncover and interrogate important molecular pathways in cancer. Offers training scientists in all stages of modern microscopical research from advice on experimental design and sample preparation, basic and advanced microscope operation and data acquisition through to quantitative image analysis and interpretation.
Proper citation: Beatson Institute for Cancer Research United Kingdom Beatson Advanced Imaging Resource Core Facility (RRID:SCR_023875) Copy
https://github.com/XSLiuLab/Pep2TCR
Web tool for CD4 TCR specificity prediction and biology applications. Used for accurate prediction of CD4 T cell receptor binding specificity through transfer learning and ensemble approach. Repository comprises codes of Pep2TCR, providing comprehensive guidance for researchers interested in Pep2TCR.
Proper citation: Pep2TCR (RRID:SCR_024721) Copy
MRI Research Center houses magnetic resonance scanners and highly qualified experienced staff for support of research projects with MR imaging component.
Proper citation: University of Chicago MRI Research Center Core Facility (RRID:SCR_024723) Copy
https://kimlab.io/brain-map/epDevAtlas/
Suite of open access resources including 3D atlases of early postnatally developing mouse brain and mapped cell type density growth charts, which can be used as standalone resources or to implement data integration. Web platform can be utilized to analyze and visualize the spatiotemporal growth of GABAergic, microglial, and cortical layer-specific cell type densities in 3D. Morphologically averaged symmetric template brains serve as the basis reference space and coordinate system with an isotropic resolution of 20 μm (XYZ in coronal plane). Average transformations were conducted at 20 μm voxel resolution by interpolating high resolution serial two photon tomography images from primarily Vip-IRES-Cre;Ai14 mice at postnatal (P) ages P4, P6, P8, P10, P12, and P14. For all ages, anatomical labels from the P56 Allen Mouse Brain Common Coordinate Framework (Allen CCFv3) were iteratively down registered to each early postnatal time point in a non-linear manner, aided by manual parcellations of landmarks in 3D, consistent with the Allen Mouse Reference Atlas Ontology.
Proper citation: Early Postnatal Developmental Mouse Brain Atlas (RRID:SCR_024725) Copy
https://tnprc.tulane.edu/anatomic-pathology-core
Anatomic Pathology Core is responsible for post-mortem examinations, tissue collection and distribution, fixation, processing, slide preparation, routine and special staining, and diagnostic gross and histologic pathology services. Processes and interprets biopsy specimens for both research and diagnostic purposes and provides tissue trimming, paraffin processing, sectioning, and routine and special staining for clinical and research staff and faculty. APC works closely with clinical veterinarians, and through diagnostic pathology on biopsies and necropsies, plays major role in monitoring and maintaining health of animals in breeding colonies.
Proper citation: Tulane University TNBRC Anatomic Pathology Core Facility (RRID:SCR_024606) Copy
https://www.huck.psu.edu/core-facilities/proteomics-and-mass-spectrometry-core-facility
Facility offers highly sensitive and accurate mass spectrometry analysis, including identification and quantitation of proteins by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS-MS) or by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-TOF-MS).
Proper citation: Pennsylvania State University Huck Institutes Proteomics and Mass Spectrometry Core Facility (RRID:SCR_024462) Copy
https://scikit-learn.org/stable/modules/generated/sklearn.svm.LinearSVC.html
Software application for linear support vector classification. Used in classification problems.
Proper citation: LinearSVC (RRID:SCR_024741) Copy
https://github.com/CahanLab/singleCellNet
Software tool to classify single cell RNA-Seq data across platforms and across species.
Proper citation: SingleCellNet (RRID:SCR_024742) Copy
https://github.com/nickpetersen93/LIQ_HD
Arduino code, 3D print design files, and tutorial video on how to build LIQ HD system. Open source tool for recording undisturbed two-bottle drinking behavior in home cage environment. All designs and software are open source to allow other researchers to build on the system and adapt LIQ HD to their animal home cages.
Proper citation: Lick Instance Quantifier Home cage Device (RRID:SCR_023802) Copy
https://www.huck.psu.edu/core-facilities/microscopy-facility
Microscopy facility specializes in areas of optical microscopy, electron microscopy, and histology. Facility is equipped with confocal microscopes, research fluorescence microscopes, and transmission and scanning electron microscopes. Research staff engage in experimentation, training, project collaboration, and consultation.
Proper citation: Pennsylvania State University Huck Institutes Microscopy Core Facility (RRID:SCR_024457) Copy
https://tnbrc.tulane.edu/cores-and-services/flow-cytometry
Core provides analytical flow cytometry services and live cell sorting under enhanced Biosafety Level 2 conditions. Instruments available include six analyzers ranging from 4-30 color acquisition and three sorters using 1-,2-,4-way, and plate sorting between 6-18 colors. Provides experimental and panel design consultation. Provides continued education in seminar format and one-on-one sessions with user.
Proper citation: Tulane University TNBRC Flow Cytometry Core Facility (RRID:SCR_024611) Copy
https://www.atypicaldiabetesnetwork.org/
Portal dedicated to characterizing, discovering and defining rare and atypical forms of diabetes. Network of universities, hospitals and clinics across the United States dedicated to better understanding atypical diabetes. Team of academic institutions and scientists collaborates with physicians and healthcare groups to identify those with atypical diabetes and learn more about their health.
Proper citation: Rare and Atypical Diabetes Network (RRID:SCR_024732) Copy
https://www.huck.psu.edu/core-facilities/fermentation-facility
Biotechnology pilot plant capable of research and pilot scale production of microbial cells, recombinant proteins, and other microbial products over wide range of controlled conditions. Facility provides equipment and expertise to university affiliated and independent government and industry researchers interested in fermentation and related technologies, including cell separation and disruption, biomolecule production and purification, and process monitoring.
Proper citation: Pennsylvania State University Huck Institutes CSL Behring Fermentation Core Facility (RRID:SCR_024459) Copy
https://tnprc.tulane.edu/confocal-microscopy-and-molecular-pathology-core
Core provides research support and training with molecular pathology skills, confocal microscopy, image analysis, and multicolor immunohistochemistry and in-situ hybridization techniques for internal and affiliate scientists. Services include assistance with experimental design, antibody selection, molecular probe selection, fixation and staining protocols, operating fluorescent and confocal microscopes, acquiring and storing imaging data, interpretation of results, and generation of publication-quality images. Image analysis services include assistance with capturing images for evaluation and with use of various image analysis software.
Proper citation: Tulane University TNBRC Confocal Microscopy and Molecular Pathology Core Facility (RRID:SCR_024613) Copy
https://tnprc.tulane.edu/pathogen-detection-and-quantification-core
THIS RESOURCE IS NO LONGER AVAILABLE. SAME SERVICES ARE AVAILABLE IN Molecular Virology and Sequencing Core. Documented on January 28,2025. Core provides services for maintaining Specific Pathogen Free status in macaque breeding colonies. Services include antibody detection in serum or plasma by Luminex-based assays and /or ELISA for SPF-agents like SIV, SRV, STLV, B virus, SFV. CMV, RRV, SVV, SV40, and LCV, and non-SPF infectious agents like measles, Burkholderia pseudomallei, Tripanosoma cruzi, Mycobacterium tuberculosis, and SARS-CoV-2. Offers services of cytokines quantification, and molecular assays for detection of SRV, CMV, SFV, and RRV.Performs nucleic acid purification from blood and tissue samples as well as qPRC for SIV viral load in plasma, cells, or tissue.
Proper citation: Tulane University TNPRC Pathogen Detection and Quantification Core Facility (RRID:SCR_024614) Copy
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