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https://www.augusta.edu/research/core/human-physiology.php

Core provides services including body/bone composition, comprehensive assessments of cardiovascular health (conduit vessel, microvascular, and central arterial stiffness), comprehensive assessment of lung health (spirometry, diffusion, lung clearance index, exhaled NO), and metabolic/exercise testing. Expanded core services in humans include oral glucose tolerance testing and continuous glucose monitoring, 24h ambulatory blood pressure monitoring, and assessments of autonomic nervous system, cognitive function, mitochondrial function, intramuscular fat, and electrocardiograms.

Proper citation: Augusta University Human Physiology Core Facility (RRID:SCR_027270) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/cruk-si-research/laboratory-operations/scientific-services.html

Offers processing fixed tissue for paraffin-embedded histology, cryo-microtomy, cell pellet processing, H+E staining and special histology stains or cellular material supplied. Immunohistochemistry, immunofluorescence and in-situ hybridisation service is available along with the capability to provide digital scanning and analysis. Many other techniques such as provision of tissue microarrays and other staining techniques such as TUNEL can be provided or set-up as required.

Proper citation: Cancer Research UK Scotland Institute Histology Core Facility (RRID:SCR_027306) Copy   

•   Source: SciCrunch Registry

https://emfacility.science.oregonstate.edu/

Core offers negative staining of protein, tissue processing including dehydration, fixation, staining and utra-microtomy, image biological samples at 80 keV on Generation 2 Titan with Rio CMOS side mount camera for low magnification too high magnification shots of cellular structures. Can also rapidly screen grids with Helios STEM in SEM capability. Provides Helios with auto slicenview and fully licensed Avizo for rendering 3D images of cells.

Proper citation: Oregon State University Electron Microscopy Core Facility (RRID:SCR_027308) Copy   

•   Source: SciCrunch Registry

https://www.iqm.unicamp.br/institucional/infraestrutura/cemuiq/lirmn

Institutional laboratory of Nuclear Magnetic Resonance (NMR) of the Institute of Chemistry of UNICAMP.The Institutional Nuclear Magnetic Resonance Laboratory has 6 NMR spectrometers, two for solids and four for solution probes, with the possibility of analyzing different nuclei.

Proper citation: State University of Campinas Institute of Chemistry Nuclear Magnetic Resonance Laboratory LIRMN-IQ Core Facility (RRID:SCR_027247) Copy   

•   Source: SciCrunch Registry

https://wertheim.scripps.ufl.edu/cores-and-technologies/genetic-perturbation-screening/

Core provides guidance in planning and helps with executing gene expression modulation experiments. Currently uses technology based on shRNA for gene knock-down and cDNA libraries for overexpression studies. Core is equipped with genome-wide retroviral shRNA libraries for both human and mouse genomes, Mammalian Gene Collection (MGC) cDNA library, as well as smaller focused sets targeting selected gene families.

Proper citation: Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology Genetic Perturbation Screening Core Facility (RRID:SCR_027255) Copy   

•   Source: SciCrunch Registry

https://research.weill.cornell.edu/core-facilities/human-therapeutic-organoid-core

Facility serves as central facility for human organoid technology to accelerate organoid-based scientific discovery. Provides human pluripotent stem cell (hPSC) derived as well as tissue derived cells and organoids.

Proper citation: Weill Cornell Medicine Human Therapeutic Organoid Core Facility (RRID:SCR_027251) Copy   

•   Source: SciCrunch Registry

https://www.ucl.ac.uk/lifesciences-faculty/laboratory-molecular-cell-biology/research/platforms-and-facilities/electron-microscopy

Electron microscopy facility specialising in cell biological electron microscopy for basic and medical research applications.

Proper citation: University College London LMCB Electron Microscopy Core Facility (RRID:SCR_027340) Copy   

•   Source: SciCrunch Registry

https://imss.lnma.mx/inicio.php

Core provides optical microscopy and histology services.

Proper citation: Mexican Social Security Institute National Laboratory of Advanced Microscopy IMSS Core Facility (RRID:SCR_027351) Copy   

•   Source: SciCrunch Registry

https://www.iqm.unicamp.br/institucional/infraestrutura/cemuiq/liafq/

Laboratory for Physicochemical Analysis of IQ-UNICAMP houses equipment for a range of analytical techniques:Thermal Analysis comprises techniques that measure the physical or chemical properties of a substance, or its reaction products, under controlled temperature variation;Atomic Spectrometry enables multi-element determination in solution samples;Elemental Analysis is used to determine the Carbon, Hydrogen, and Nitrogen content in solid and viscous samples.Nitrogen Physisorption is a technique used to determine the surface area and pore size of solid materials.

Proper citation: State University of Campinas LIAFQ-IQ Laboratory of Physicochemical Analysis Core Facility (RRID:SCR_027389) Copy   

•   Source: SciCrunch Registry

https://medresearch.umich.edu/labs-departments/labs/nucleic-acid-therapeutics

Nucleic Acid Therapeutics Core accelerates the development of gene-targeted therapies by providing custom oligonucleotide synthesis, expert consultation, and platform for cross-disciplinary collaboration.

Proper citation: University of Michigan Medical School Nucleic Acid Therapeutics Core Facility (RRID:SCR_027422) Copy   

•   Source: SciCrunch Registry

https://vrlab.isr.umich.edu/

Core provides flexible systems with built-in support for biometric data collection, dyadic interactions, and reproducible protocols. Provides access to pipelines that support reproducibility, custom data annotation, and seamless handoff to analysis tools in R, Python, and more. Provides access to IRB-ready templates and documentation, along with tested participant safety protocols and secure data management systems.

Proper citation: University of Michigan ISR-VR Lab Core Facility (RRID:SCR_027421) Copy   

•   Source: SciCrunch Registry

https://sc.edu/rc

Reporting to the Division of Information Technology, and working in close partnership with the Office of Research, works with researchers to improve their project performance and secure computing resources not only at the university level but beyond, to National Labs and other high profile HPC resources.

Proper citation: University of South Carolina Research Computing Core Facility (RRID:SCR_027488) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/advanced-technologies/deep-phenotyping.html

Core offers comprehensive pathologist-led spatial biology service comprising spatial proteomic, transcriptomic, and multiomic experimental design, including platform and panel selection, assay development, image acquisition, and digital image processing. The facility houses 2x Ventana Discovery Ultra autostainers, 2x 10 x Genomics Xenium platforms, a Lunaphore COMET, an Akoya PhenoImager, an Akoya PhenoCycler, an Olympus VS200 slide scanner and a Visiopharm image analysis suite.

Proper citation: CRUK Scotland Institute Deep Phenotyping Advanced Technology Core Facility (RRID:SCR_027366) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/advanced-technologies/molecular-technology.html

Core provides Next Generation Sequencing (NGS) services and Single Cell services predominantly focussing on single cell RNAseq. Processes samples for variety of cancer associated projects, in both mouse and human derived materials. Offers full end-to-end service, from initial study design and planning, through sample QC, full library preparation, sequencing and data return. Offers range of standard molecular tests covering, plasmid purifications, Sanger sequencing and mycoplasma screening.

Proper citation: Cancer Research UK Scotland Institute Molecular Technology Service Core Facility (RRID:SCR_027368) Copy   

•   Source: SciCrunch Registry

https://www.lsuhs.edu/centers/cardiovascular-diseases-and-sciences/research-resources/core-facilities

Core provides centralized service for performing technically challenging mouse models of cardiovascular disease, such as middle cerebral artery occlusion (MCAO) stroke model, coronary artery ligation model of myocardial ischemia, femoral artery ligation model of peripheral artery disease, and partial carotid artery ligation model of disturbed blood flow.

Proper citation: Louisiana State University in Shreveport Center for Cardiovascular Diseases and Sciences (CCDS) Surgical Models Core Facility (RRID:SCR_027497) Copy   

•   Source: SciCrunch Registry

https://www.lsuhs.edu/centers/cardiovascular-diseases-and-sciences/research-resources/core-facilities

Core provides centralized service for generating AAV particles for cardiovascular studies. The CCDS Virus Production Core offers the production of either pre-made (ex. AAV8-GFP, AAV8 mPCSK9 D377Y) or custom AAVs.

Proper citation: Louisiana State University in Shreveport Center for Cardiovascular Diseases and Sciences (CCDS) Virus Production Core Facility (RRID:SCR_027498) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/cancer/research/shared-resources/bioinformatics/

Georgia Cancer Center's Bioinformatics Core provides expertise in integrative computational based analysis solutions to basic, clinical, and translational research applications. Services include study design, analysis, and interpretation that may involve interaction with industry, government, and regulatory agencies in the areas of Clinical trials, Epidemiology, laboratory studies, in addition to data mining using local and national databases for hypotheses generation and scientific investigation.

Proper citation: Augusta University Bioinformatics Shared Resource Core Facility (RRID:SCR_027372) Copy   

•   Source: SciCrunch Registry

https://www.med.uvm.edu/bsr/home

Core offers bioinformatics and data modeling services. Focuses on support for reproducible, well documented, containerized, nextflow pipelines customized to address the specific research questions and biological systems of the investigators. Offers support from preprocessing -omics data, through data integration and manuscript support, based on grant support or a fee-for-service mechanism. Provides training for students and PIs in the form of individual help, seminars, and workshops.

Proper citation: University of Vermont Bioinformatics Shared Resource Core Facility (RRID:SCR_027493) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/light-microscopy/

Core services include: basic light microscopy (determine appropriate staining protocols and offer training and/or assistance in acquiring transmitted and fluorescent digital images with wide-field microscopes); optical sectioning (training and assistance in the use of confocal and multi-photon microscopes); whole slide scanning (brightfield or fluorescence mode). Laser MicroDissection instruments are available for isolating small areas of tissue or single cells. Total Interference Reflection Fluorescence (TIRF) microscopy is available for visualizing and quantifying cellular events localized at the basal plasma membrane. Live cell and tissue imaging can be done on both wide-field and confocal microscopes equipped with environmental chambers for heat/CO2 control.Investigators have access to Image Processing and Analysis workstations with variety of advanced software for extracting quantitative data from their images. They can also generate images and movies for presentations, grants and publications. Core is home to 2 LI-COR Odyssey, laser-based scanning systems for gels, Westerns, in-cell Westerns, ELISA/FLISA, EMSA/Gel Shift, Protein Detection, etc.

Proper citation: Cleveland Clinic Lerner Research Institute Light Microscopy Core Facility (RRID:SCR_027477) Copy   

•   Source: SciCrunch Registry

https://www.houstonmethodist.org/academic-institute/research/cores/

Core is fee-for-service research laboratory providing internal and external users a wide spectrum of electron microscopy (EM) techniques. As part of the Houston Methodist Research Institute Department of Neurology, we routinely process samples related to the peripheral nervous system but can help with the ultrastructural study of many biological samples.

Proper citation: Houston Methodist HMRI Neurology Electron Microscopy Core Facility (RRID:SCR_027479) Copy   

•   Source: SciCrunch Registry