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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.ncbi.nlm.nih.gov/biosystems/
Database that provides access to biological systems and their component genes, proteins, and small molecules, as well as literature describing those biosystems and other related data throughout Entrez. A biosystem, or biological system, is a group of molecules that interact directly or indirectly, where the grouping is relevant to the characterization of living matter. BioSystem records list and categorize components, such as the genes, proteins, and small molecules involved in a biological system. The companion FLink tool, in turn, allows you to input a list of proteins, genes, or small molecules and retrieve a ranked list of biosystems. A number of databases provide diagrams showing the components and products of biological pathways along with corresponding annotations and links to literature. This database was developed as a complementary project to (1) serve as a centralized repository of data; (2) connect the biosystem records with associated literature, molecular, and chemical data throughout the Entrez system; and (3) facilitate computation on biosystems data. The NCBI BioSystems Database currently contains records from several source databases: KEGG, BioCyc (including its Tier 1 EcoCyc and MetaCyc databases, and its Tier 2 databases), Reactome, the National Cancer Institute's Pathway Interaction Database, WikiPathways, and Gene Ontology (GO). It includes several types of records such as pathways, structural complexes, and functional sets, and is desiged to accomodate other record types, such as diseases, as data become available. Through these collaborations, the BioSystems database facilitates access to, and provides the ability to compute on, a wide range of biosystems data. If you are interested in depositing data into the BioSystems database, please contact them.
Proper citation: NCBI BioSystems Database (RRID:SCR_004690) Copy
A volunteer, not for profit organization providing leadership in supporting research of LeioMyoSarcoma, improving treatment outcomes of those affected by this disease as well as fostering awareness in the medical community and general public. All dollars go to research and awareness. Leiomyosarcoma is a rare form of cancer, which affects about four people in every million. It spreads through the blood stream and can affect the lungs, liver, blood vessels or any other soft tissue in the body. Presently there is no cure, only remission if it can be attained, and this rare cancer can reappear anywhere and at any time. Because of its rarity, few doctors know how to treat it and it attracts little research. The National LeioMyoSarcoma Foundation hosts several Fundraising events throughout the year.
Proper citation: National LeioMyoSarcoma Foundation (RRID:SCR_004692) Copy
A web-based browser for Gene Ontology terms and annotations, which is provided by the UniProtKB-GOA group at the EBI. It is able to offer a range of facilities including bulk downloads of GO annotation data which can be extensively filtered by a range of different parameters and GO slim set generation. The software for QuickGO is freely available under the Apache 2 license. QuickGO can supply GO term information and GO annotation data via REST web services.
Proper citation: QuickGO (RRID:SCR_004608) Copy
Network evaluating consensus-based common data elements (CDE) for traumatic brain injury (TBI) and psychological health (TBI-CDE, www.commondataelements.ninds.nih.gov/TBI.aspx) while extensively phenotyping a cohort of TBI patients across the injury spectrum from concussion to coma. Institutions that participate in the TBI Network will be able to track the outcomes of patients through a 3, 6 and 12-month followup program and compare outcomes with other participating institutions. For the three acute care centers, patients were enrolled that presented to the emergency department within 24 hours of head injury and required computed tomography (CT). For the rehabilitation center, referrals from acute hospitals were enrolled. Patients were consented to participate in components: clinical profile; blood draws for measurement of proteomic and genomic markers; 3T MRI within 2 weeks; three-month Glasgow Outcome Scale-Extended (GOS-E); and six-month TBI-CDE Core outcome assessments. A web-enabled database, imaging repository, and biospecimen bank was developed using the TBI-CDE recommendations. A total of 605 patients were enrolled. Of these subjects, 88% had a GCS 13-15, 5% had a GCS 9-12, and 7% had a GCS of 8 or less. Three-month GOS-E''s were obtained for 78% of the patients. Comprehensive 6-month outcome measures, including PTSD assessment, are ongoing until September 2011. Blood specimens were collected from 450 patients. Initial CTs for 605 patients and 235 patients with 3T MRI studies were transferred to an imaging repository. The TRACK TBI Network will provide qualified institutions access to a web-based version of key forms in tracking TBI outcomes for Quality Improvement and institutional benchmarking.
Proper citation: TRACK TBI Network (RRID:SCR_004723) Copy
Database providing access to quality controlled Open Access Journals. For a journal to be included it should exercise quality control on submitted papers through an editor, editorial board and/or a peer-review system. It is not be limited to particular languages or subject areas. Offering free online access to high quality full text content, plus excellent search tools, the portal enables researchers to find, use and re-use a vast range of materials with ease. The content of DOAJ will be even more visible and disseminated through this portal. The aim of the Directory is to increase the visibility and ease of use of open access scientific and scholarly journals thereby promoting their increased usage and impact. As of April 2014, DOAJ has 9,709 journals, 5,624 journals searchable at article level, 133 Countries and 1,600,991 articles. The database may be browsed by title or subject, or searched through the interface to for journals or articles.
Proper citation: DOAJ - Directory of Open Access Journals (RRID:SCR_004521) Copy
Collection based on a collaborative effort of popular neuroscience research software for the Debian operating system as well as Ubuntu and other derivatives. Popular packages include AFNI, FSL, PyMVPA and many others. It contains both unofficial or prospective packages which are not (yet) available from the main Debian archive, as well as backported or simply rebuilt packages also available elsewhere. A listing of current and planned projects is available if you want to get involved. The main goal of the project is to provide a versatile and convenient environment for neuroscientific research that is based on open-source software. To this end, the project offers a package repository that complements the main Debian (and Ubuntu) archive. NeuroDebian is not yet another Linux distribution, but rather an effort inside the Debian project itself. Software packages are fully integrated into the Debian system and from there will eventually migrate into Ubuntu as well. With NeuroDebian, installing and updating neuroscience software is no different from any other part of the operating system. Maintaining a research software environment becomes as easy as installing an editor. There is also virtual machine to test NeuroDebian on Windows or Mac OS. If you want to see your software packaged for Debian, please drop them a note.
Proper citation: neurodebian (RRID:SCR_004401) Copy
http://askdrwiki.com/mediawiki/index.php?title=Physician_Medical_Wiki
A medical, nonprofit, educational wiki created to support a collective online memory for physicians, nurses, and medical students. Users can publish review articles, clinical notes, pearls, and medical images on the site. Anyone with a medical background can contribute to or edit medical articles. Images include: EKG, x-ray, coronary angiograms, peripheral angiograms, structural angiograms, searchable angiograms, echocardiograms, and radiology. Tutorials include: EKG tutorials, coronary angiography tutorials, and ventriculography tutorials.
Proper citation: Ask Dr Wiki (RRID:SCR_004524) Copy
http://en.ecgpedia.org/wiki/Main_Page
Free online electrocardiography (ECG) course and textbook via a wiki where anyone can contribute and changes are supervised by physicians. Learn from cases and examples. It designed for medical professionals such as cardiac care nurses and physicians. All content is freely accessible. The information on this site should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. For questions like these we advise you to contact your physician.
Proper citation: ECGpedia (RRID:SCR_004486) Copy
http://www.researchinformatics.org/
An open-access portal for discussion, information sharing, and collaboration among those working to advance the rapidly developing field of clinical research informatics (CRI). We hope that you find the content useful and that you use our interactive features to contribute your knowledge and experience for the benefit of our community. Research Informatics.org Contents include: * CRI Initiatives * CRI News * CRI Events * CRI Resources * CRI Wiki * CRI Forum * CRI Blog
Proper citation: ResearchInformatics.org (RRID:SCR_004487) Copy
http://nematode.lab.nig.ac.jp/
Expression pattern map of the 100Mb genome of the nematode Caenorhabditis elegans through EST analysis and systematic whole mount in situ hybridization. NEXTDB is the database to integrate all information from their expression pattern project and to make the data available to the scientific community. Information available in the current version is as follows: * Map: Visual expression of the relationships among the cosmids, predicted genes and the cDNA clones. * Image: In situ hybridization images that are arranged by their developmental stages. * Sequence: Tag sequences of the cDNA clones are available. * Homology: Results of BLASTX search are available. Users of the data presented on our web pages should not publish the information without our permission and appropriate acknowledgment. Methods are available for: * In situ hybridization on whole mount embryos of C.elegans * Protocols for large scale in situ hybridization on C.elegans larvae
Proper citation: NEXTDB (RRID:SCR_004480) Copy
http://scientificdatasharing.com/
While many data sharing programs exist worldwide, widespread sharing of raw data has not yet won across-the-board acceptance in the scientific community, and the very existence of all these databases makes the approach fractured at best. The Data Sharing Project, launched last year by University of California-San Francisco Professor Michael Weiner, has two goals: One is to make widespread raw data sharing a reality initially in the realm of medicine through creation of a repository system accessible to all researchers; the second goal is to foster broad scientific support for this move and its adoption in other fields of research. With major projects such as the Human Genome Project demonstrating the tremendous scientific breakthroughs made possible by data sharing and with the decline of technological barriers impeding such efforts, the time has come to work to achieve widespread sharing of raw data worldwide. The Data Sharing Project proposes to further this goal initially in the field of medicine by working to create a raw data sharing program that will serve as a model to other disciplines attempting to make their own way in this arena. The Northern California Institute for Research and Education (NCIRE) together with the University of California-San Francisco and support from the Michael J. Fox Foundation is now in the process of canvassing the scientific community to analyze the best possible data sharing program and practices to establish in the field of medicine.
Proper citation: Scientific Data Sharing Project (RRID:SCR_004481) Copy
http://www.mscenter.org/research/tissue-bank/
Scientists throughout the world depend on the Rocky Mountain MS Center Tissue Bank to supply high quality human brain tissue and cerebral spinal fluid to support their research. Funded in part by the National MS Society, the Tissue Bank is one of only four MS-related tissue banks in the nation. The Tissue Bank has distributed specimens to more than 160 investigators worldwide and over 1,600 people have consented to be donors after death. Tissue banks provide a unique bridge between those who live with MS and the scientific community. Studies conducted with samples from the Center have led to several important discoveries and 130 publications. While deeply personal, the decision to donate has far-reaching effects as scientists unlock the mysteries of multiple sclerosis. If you would like to donate, arrangements must be made in advance because it is important that tissue is taken within a few hours of death. For more information on making a donation, visit the How To Donate section of this website and contact the Rocky Mountain MS Center Tissue Bank at 303.788.4030 x111.
Proper citation: Rocky Mountain MS Center Tissue Bank (RRID:SCR_004361) Copy
https://krieger.jhu.edu/neuroscience
Undergraduate Program in Neuroscience offers broad overview of field, as well as more advanced training in one of four specialized areas: cellular and molecular, cognitive, computational, or systems neuroscience.
Proper citation: Johns Hopkins University; Undergraduate Neuroscience Program (RRID:SCR_004638) Copy
http://www.mged.org/index.html
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 7, 2022. Functional Genomics Data Society - FGED Society, founded in 1999 as the MGED Society, advocates for open access to genomic data sets and works towards providing concrete solutions to achieve this. Our goal is to assure that investment in functional genomics data generates the maximum public benefit. Our work on defining minimum information specifications for reporting data in functional genomics papers have already enabled large data sets to be used and reused to their greater potential in biological and medical research. We work with other organizations to develop standards for biological research data quality, annotation and exchange. We facilitate the creation and use of software tools that build on these standards and allow researchers to annotate and share their data easily. We promote scientific discovery that is driven by genome wide and other biological research data integration and meta-analysis.
Proper citation: Functional Genomics Data Society (RRID:SCR_004358) Copy
SysMO-DB is a project that is creating a web-based platform, and tooling, for finding, sharing and exchanging Data, Models and Processes in Systems Biology. It was designed to support the SysMO Consortium (Systems Biology for Micro-Organisms), but the principles and methods employed are equally applicable to other multi-site Systems Biology projects. All code is open source and available for download. SEEK, a component of SysMO-DB, is a private community collaboration and asset sharing platform for Systems Biology models, data and protocols serving 120 research institutions throughout Europe. SEEK is the main web-based access point to the system and provides an access control layer to enable researchers to restrict access to collaborators, colleagues or other individuals until they are ready to share with the whole consortium or the wider community. The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that: * facilitates and maximizes the potential for data exchange between SysMO research groups; * maximizes the ''shelf life'' and utility of data generated by SysMO; * provides an integrated platform for the dissemination of the results of the SysMO projects to the scientific community; and * facilitates standardization of practices in Systems Biology for the interfacing of modeling and experimentation. We follow several key principles: * exploit what is already available, both within the consortium and outside it, and do not reinvent; * identify the least we can do to make a benefit and do this incrementally. SysMO-DB will soon be opening it up to the wider scientific community, but for now it is currently only available for those within the SysMO consortium.
Proper citation: SysMO-DB (RRID:SCR_004479) Copy
http://www.jtcancercenter.org/
Throughout the past 25 years, John Theurer Cancer Center at Hackensack University Medical Center has become one of the largest and most comprehensive cancer centers in the United States. Today, we are a top 50 U.S. News and World Report Best Hospitals for cancer the only cancer center in New Jersey with this prestigious designation. Its mission is to deliver extraordinary care that is multidisciplinary, personalized, innovative, and at the appropriate cost with superior outcomes to the most satisfied patients. Year after year, we have harnessed the newest technologies and retained world-class physicians, nurses and scientists to help service the needs of our patients within our 14 specialized cancer divisions.
Proper citation: John Theurer Cancer Center (RRID:SCR_004359) Copy
Public database of information about all clinical trials involving humans, this global initiative provides a single point of access to information about ongoing and completed clinical trials. It contains the trial registration data sets made available by data providers around the world meeting criteria for content and quality control. It also aims to: * To improve the comprehensiveness, completeness and accuracy of registered clinical trial data * To communicate and raise awareness of the need to register clinical trials * To ensure the accessibility of registered data * To build capacity for clinical trial registration * To encourage the utilization of registered data * To ensure the sustainability of the ICTRP The mission of the WHO International Clinical Trials Registry Platform is to ensure that a complete view of research is accessible to all those involved in health care decision making. This will improve research transparency and will ultimately strengthen the validity and value of the scientific evidence base. The registration of all interventional trials is a scientific, ethical and moral responsibility. The ICTRP: * Publishes the ICTRP Search Portal * Supports the WHO Registry Network * Supports countries and regions wanting to establish WHO-compliant clinical trial registries or policies on trial registration.
Proper citation: WHO International Clinical Trials Registry Platform (RRID:SCR_004475) Copy
http://www.rarebreeds.co.nz/genebank.html
Not yet vetted by NIF curator
Proper citation: Rare Breeds Gene Bank (RRID:SCR_010728) Copy
http://diana.imis.athena-innovation.gr/DianaTools/index.php?r=tarbase/index
Manually curated database of experimentally supported animal microRNA targets. Collection of experimentally supported miRNA gene interactions.
Proper citation: TarBase (RRID:SCR_010841) Copy
Provides sterile biologic implants of human bone and tissues used in spine, sports medicine, orthopedic, dental and other specialty surgeries.
Proper citation: RTI Biologics (RRID:SCR_010721) Copy
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