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https://www.med.uvm.edu/bsr/home

Core offers bioinformatics and data modeling services. Focuses on support for reproducible, well documented, containerized, nextflow pipelines customized to address the specific research questions and biological systems of the investigators. Offers support from preprocessing -omics data, through data integration and manuscript support, based on grant support or a fee-for-service mechanism. Provides training for students and PIs in the form of individual help, seminars, and workshops.

Proper citation: University of Vermont Bioinformatics Shared Resource Core Facility (RRID:SCR_027493) Copy   

•   Source: SciCrunch Registry

https://www.ucl.ac.uk/lifesciences-faculty/laboratory-molecular-cell-biology/research/platforms-and-facilities/electron-microscopy

Electron microscopy facility specialising in cell biological electron microscopy for basic and medical research applications.

Proper citation: University College London LMCB Electron Microscopy Core Facility (RRID:SCR_027340) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/light-microscopy/

Core services include: basic light microscopy (determine appropriate staining protocols and offer training and/or assistance in acquiring transmitted and fluorescent digital images with wide-field microscopes); optical sectioning (training and assistance in the use of confocal and multi-photon microscopes); whole slide scanning (brightfield or fluorescence mode). Laser MicroDissection instruments are available for isolating small areas of tissue or single cells. Total Interference Reflection Fluorescence (TIRF) microscopy is available for visualizing and quantifying cellular events localized at the basal plasma membrane. Live cell and tissue imaging can be done on both wide-field and confocal microscopes equipped with environmental chambers for heat/CO2 control.Investigators have access to Image Processing and Analysis workstations with variety of advanced software for extracting quantitative data from their images. They can also generate images and movies for presentations, grants and publications. Core is home to 2 LI-COR Odyssey, laser-based scanning systems for gels, Westerns, in-cell Westerns, ELISA/FLISA, EMSA/Gel Shift, Protein Detection, etc.

Proper citation: Cleveland Clinic Lerner Research Institute Light Microscopy Core Facility (RRID:SCR_027477) Copy   

•   Source: SciCrunch Registry

https://www.houstonmethodist.org/academic-institute/research/cores/

Core is fee-for-service research laboratory providing internal and external users a wide spectrum of electron microscopy (EM) techniques. As part of the Houston Methodist Research Institute Department of Neurology, we routinely process samples related to the peripheral nervous system but can help with the ultrastructural study of many biological samples.

Proper citation: Houston Methodist HMRI Neurology Electron Microscopy Core Facility (RRID:SCR_027479) Copy   

•   Source: SciCrunch Registry

https://rcgd.isr.umich.edu/research/facilities/zajonc-lab/

Core provides researchers with facilities to conduct experimental research, particularly within the Research Center for Group Dynamics (RCGD) and across the U-M campus. The labs offer adaptable room configurations, specialized software like E-Prime and z-Tree, and shared access to cutting-edge technology, including a new Virtual Reality (VR) Lab, to support a range of interdisciplinary research projects focused on human social behavior and dynamics.

Proper citation: University of Michigan Robert B. Zajonc Experimental Lab Core Facility (RRID:SCR_027478) Copy   

•   Source: SciCrunch Registry

https://imss.lnma.mx/inicio.php

Core provides optical microscopy and histology services.

Proper citation: Mexican Social Security Institute National Laboratory of Advanced Microscopy IMSS Core Facility (RRID:SCR_027351) Copy   

•   Source: SciCrunch Registry

https://chem.vt.edu/analyticalservices/surface-analysis-lab.html

Core offers contemporary surface analysis techniques, featuring the latest PHI VersaProbe III Scanning XPS Microscope, and expertise.

Proper citation: Virginia Tech VT Surface Analysis Laboratory Core Facility (RRID:SCR_027504) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/resources/deans-cores/neuropathology

Provides access to collection of human postmortem brain tissues, including fresh, frozen, and formalin-fixed paraffin-embedded (FFPE) specimens, along with detailed clinical histories and neuropathological assessments. Available histology services include processing and embedding, slide sectioning for FFPE and cryosections, immunohistochemistry (IHC), immunofluorescence (IF), and advanced RNA assays such as RNAscope, BaseScope, and miRscope. High-resolution digital slide imaging is performed using the GT450 scanner. CoRE scientists also collaborate with investigators and trainees to support project development, method optimization and troubleshooting, data analysis.

Proper citation: Icahn School of Medicine at Mount Sinai Neuropathology Brain Bank and Research CoRE Facility (RRID:SCR_027565) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/it/hpcs/

Core provides high memory parallel processing environments and software in support of the university research, academic, and cybersecurity missions. HPC clusters use multiple computers to process data in parallel, greatly reducing the time to solution for most computational science tasks. They also provide storage to manage very large data sets.

Proper citation: Augusta University High Performance Computing Core Facility (RRID:SCR_027680) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/human-immune-monitoring-center

Core provides team of experts in the characterization of immune profiles and treatment responses across a diverse range of diseases, such as cancer, autoimmunity, allergy, and neuro-immune disorders. Offers equipment in the field for research at Genomic, cellular and proteomic analysis. Develops assays to balance innovation with protocols and operating procedures to ensure data quality and reproducibility.

Proper citation: Icahn School of Medicine at Mount Sinai Human Immune Monitoring Center Core Facility (RRID:SCR_027571) Copy   

•   Source: SciCrunch Registry

https://medicine.tulane.edu/microbiology-immunology/flow-cytometry-and-cell-sorting-facility

Tulane University School of Medicine Department of Microbiology/Immunology Flow cytometry and cell sorting shared resource facility. Provides education, training and services, Applications include analysis and sorting of immune subsets and fluorescent-reporter expressing cells, DNA content, multi-plex bead assays and functional assays. Expert assistance with experimental design and data analysis, as well as instrument training, are available at no charge.

Proper citation: Tulane University School of Medicine Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_027605) Copy   

•   Source: SciCrunch Registry

https://www.mayo.edu/research/core-resources/antibody-hybridoma-core/overview

Core can generate custom monoclonal antibodies in mouse and hamster systems. Can also produce large amounts of antibodies (of all species) and recombinant proteins in-vitro. Purification is also available for various systems.

Proper citation: Mayo Clinic Antibody Hybridoma Core Facility (RRID:SCR_027544) Copy   

•   Source: SciCrunch Registry

http://confocal.uconn.edu

Facility provides training and access to advanced light microscopy systems at an hourly rate. In addition, we are available to consult with and support users at every stage of a project including: experimental design, sample preparation, image acquisition, analysis, and data preparation.

Proper citation: University of Connecticut Advanced Light Microscopy Core Facility (RRID:SCR_027547) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/research/core/proteomics.php

Facility for characterization and expression level quantitation of proteins (isolated or in an extract) and small molecules/metabolites by mass spectrometry (MS) and/or chromatography. Services include protein identification, labeled and label-free comparative proteomics by Orbitrap mass spectometry, protein/small molecule quantification using targeted mass spectometry (PRM and SRM/MRM mass spectometry), high throughput protein immune-protein assays (384-well Luminex/ELISA assay), etc.

Proper citation: Augusta University Proteomics and Mass Spectrometry Core Facility (RRID:SCR_027673) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/research/core/human-mri

Core dedicated to providing cutting-edge magnetic resonance imaging services for human participants. Provides Human 3 Tesla MRI system from Siemens for human research with proper IRB approval and approved MRI protocols.

Proper citation: Augusta University Human MRI Imaging Core Facility (RRID:SCR_027672) Copy   

•   Source: SciCrunch Registry

https://www.vai.org/research/collaborations/west-michigan-neurodegenerative-diseases-mind-program/?tabUrl=ipsc-platform

Core provides iPSC cell culture laboratory with access to curated and validated iPSC lines for neurodegeneration research. Provides robotic and fully automated high-content imaging system to perform high-throughput screening on living brain cells (iPSC derived through reprogramming) to understand the mechanisms behind neurodegeneration at the molecular level.

Proper citation: Van Andel Institute MiND iPSC and Screening Platform Core Facility (RRID:SCR_027675) Copy   

•   Source: SciCrunch Registry

https://www.inecol.mx/index.php/infraestructura/laboratorios/unidad-microscopia-avanzada

Core supports research in various scientific disciplines through advanced microscopy techniques (fluorescence, electron, and optical) and micro-CT. Provides technical services, consultation and training in advanced microscopy.

Proper citation: Institute of Ecology INECOL Advanced Microscopy Unit Core Facility (RRID:SCR_027676) Copy   

•   Source: SciCrunch Registry

https://info.umkc.edu/proteomics_core_lab/

Federally funded facility committed to advancing scientific research by delivering high-quality proteomic data. Provides proteomics analysis, technology, services, and rigorous quality standards.

Proper citation: University of Missouri Kansas City UMKC Proteomics Core Facility (RRID:SCR_027679) Copy   

•   Source: SciCrunch Registry

https://research.manchester.ac.uk/en/equipments/core-facility-for-advanced-metal-development

Core supports all processing of metal related activity and houses equipment in the areas of thermomechanical processing, additive manufacturing, mechanical testing (including testing under a variety of environments), thermomechanical simulation/testing and heat treatment.

Proper citation: University of Manchester Advanced Metal Development Core Facility (RRID:SCR_027557) Copy   

•   Source: SciCrunch Registry

https://nmrcore.uhnresearch.ca/

NMR Core Facility is equipped with NMR spectrometers allowing researchers to Characterize bio-molecular structures at the atomic resolution with exquisite details;Identify protein interactions with binding partners in order to understand their architecture;Study protein dynamic;Study protein post-translational modifications acting as molecular switches;Study structure-function relationships of biological proteins to gain insight into biological processes in relation to human disease;Screening of High-throughput drug-like leads for novel therapeutic targets;Study Metabolites of interest.Core facility houses high-field NMR spectrometers equipped with cryogenically cooled probes (1H or 13C optimized) for enhanced sensitivity.

Proper citation: University Health Network Nuclear Magnetic Resonance Core Facility (RRID:SCR_027548) Copy   

•   Source: SciCrunch Registry